Sophie Corvaisier

Affiliations
  • Normandie Univ, UNICAEN, CERMN, 14000, Caen, France.

Publications (21)

8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi.

European journal of medicinal chemistry
Avec: Cyril Fersing , Clotilde Boudot , Caroline Castera-Ducros , Emilie Pinault , Sébastien Hutter , Romain Paoli-Lombardo , Nicolas Primas , Julien Pedron , Line Seguy , Sandra Bourgeade-Delmas , Alix Sournia-Saquet , Jean-Luc Stigliani , Jean-Yves Brossas , Luc Paris , Alexis Valentin , Susan Wyllie , Alan H Fairlamb , Élisa Boutet-Robinet , Sophie Corvaisier , Marc Since , Aurélie Malzert-Fréon , Alexandre Destere , Dominique Mazier , Pascal Rathelot , Bertrand Courtioux , Nadine Azas , Pierre Verhaeghe , Patrice Vanelle

New 8-Nitroquinolinone Derivative Displaying Submicromolar

ACS medicinal chemistry letters
Avec: Julien Pedron , Clotilde Boudot , Jean-Yves Brossas , Emilie Pinault , Sandra Bourgeade-Delmas , Alix Sournia-Saquet , Elisa Boutet-Robinet , Alexandre Destere , Antoine Tronnet , Justine Bergé , Colin Bonduelle , Céline Deraeve , Geneviève Pratviel , Jean-Luc Stigliani , Luc Paris , Dominique Mazier , Sophie Corvaisier , Marc Since , Aurélie Malzert-Fréon , Susan Wyllie , Rachel Milne , Alan H Fairlamb , Alexis Valentin , Bertrand Courtioux , Pierre Verhaeghe

Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT

European journal of medicinal chemistry
Avec: François-Xavier Toublet , Julien Lalut , Bérénice Hatat , Cédric Lecoutey , Audrey Davis , Marc Since , Sophie Corvaisier , Thomas Freret , Jana Sopková-de Oliveira Santos , Sylvie Claeysen , Michel Boulouard , Patrick Dallemagne , Christophe Rochais

In vitro evaluation of NA1-115-7-loaded nanoemulsions, an MCL-1-specific inhibitor of natural origin, intended to treat B-cell lymphoproliferative disorders after oral administration.

International journal of pharmaceutics
Avec: Line Séguy , Florian Daressy , Sophia Lahlil , Sophie Corvaisier , Vincent Dumontet , Marc Litaudon , Cécile Apel , Fanny Roussi , Joëlle Wiels , Aude Robert , Anne-Claire Groo , Aurélie Malzert-Fréon

Synthesis, in vitro and in vivo biological evaluation of novel dual compounds targeting both acetylcholinesterase and serotonergic 5-HT

European journal of medicinal chemistry
Avec: Christophe Rochais , Cédric Lecoutey , Julien Lalut , Audrey Davis , Emilie Duval , Florence Gaven , Stacy Largillière , Gérald Née , Sophie Corvaisier , Jana Sopkova de Oliveira Santos , Marc Since , Thomas Freret , Romain Legrand , Noëlle Callizot , Sylvie Claeysen , Michel Boulouard , Patrick Dallemagne

Synthesis of Pyridoclax Analogues: Insight into Their Druggability by Investigating Their Physicochemical Properties and Interactions with Membranes.

ChemMedChem
Avec: Martina De Pascale , Domenico Iacopetta , Marc Since , Sophie Corvaisier , Véronique Vie , Gilles Paboeuf , Didier Hennequin , Serge Perato , Marcella De Giorgi , Maria Stefania Sinicropi , Jana Sopkova-De Oliveira Santos , Anne-Sophie Voisin-Chiret , Aurélie Malzert-Freon

Quality control of rigid endoscopes: a comparative study between ScopeControl® and surgeons' evaluation.

Surgical endoscopy
Avec: Pierre Courault , Stéphane Emery , Sofia Boudour , Françoise Rochefort , Alain Ruffion , Claude Dussart , Stéphane Corvaisier

Long-Term Music Exposure Prevents Age-Related Cognitive Deficits in Rats Independently of Hippocampal Neurogenesis.

Cerebral cortex (New York, N.Y. : 1991)
Avec: Lou Rizzolo , Marianne Leger , Sophie Corvaisier , Mathilde Groussard , Hervé Platel , Valentine Bouet , Pascale Schumann-Bard , Thomas Freret

Antikinetoplastid SAR study in 3-nitroimidazopyridine series: Identification of a novel non-genotoxic and potent anti-T. b. brucei hit-compound with improved pharmacokinetic properties.

European journal of medicinal chemistry
Avec: Cyril Fersing , Clotilde Boudot , Romain Paoli-Lombardo , Nicolas Primas , Emilie Pinault , Sébastien Hutter , Caroline Castera-Ducros , Youssef Kabri , Julien Pedron , Sandra Bourgeade-Delmas , Alix Sournia-Saquet , Jean-Luc Stigliani , Alexis Valentin , Amaya Azqueta , Damián Muruzabal , Alexandre Destere , Susan Wyllie , Alan H Fairlamb , Sophie Corvaisier , Marc Since , Aurélie Malzert-Fréon , Carole Di Giorgio , Pascal Rathelot , Nadine Azas , Bertrand Courtioux , Patrice Vanelle , Pierre Verhaeghe

Synthesis of antiplasmodial 2-aminothieno[3,2-d]pyrimidin-4(3H)-one analogues using the scaffold hopping strategy.

European journal of medicinal chemistry
Avec: Romain Mustière , Prisca Lagardère , Sébastien Hutter , Viviana Dell'Orco , Nadia Amanzougaghene , Shahin Tajeri , Jean-François Franetich , Sophie Corvaisier , Marc Since , Aurélie Malzert-Fréon , Nicolas Masurier , Vincent Lisowski , Pierre Verhaeghe , Dominique Mazier , Nadine Azas , Patrice Vanelle , Nicolas Primas

Improving Aqueous Solubility and In Vitro Pharmacokinetic Properties of the 3-Nitroimidazo[1,2-

Pharmaceuticals (Basel, Switzerland)
Avec: Romain Paoli-Lombardo , Nicolas Primas , Sandra Bourgeade-Delmas , Sébastien Hutter , Alix Sournia-Saquet , Clotilde Boudot , Emilie Brenot , Caroline Castera-Ducros , Sophie Corvaisier , Marc Since , Aurélie Malzert-Fréon , Bertrand Courtioux , Alexis Valentin , Pierre Verhaeghe , Nadine Azas , Pascal Rathelot , Patrice Vanelle

NA1-115-7, from Zygogynum pancheri, is a new selective MCL-1 inhibitor inducing the apoptosis of hematological cancer cells but non-toxic to normal blood cells or cardiomyocytes.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Avec: Florian Daressy , Line Séguy , Loëtitia Favre , Sophie Corvaisier , Cécile Apel , Anne-Claire Groo , Marc Litaudon , Vincent Dumontet , Aurélie Malzert-Fréon , Sandy Desrat , Fanny Roussi , Aude Robert , Joëlle Wiels

New antiplasmodial 4-amino-thieno[3,2-d]pyrimidines with improved intestinal permeability and microsomal stability.

European journal of medicinal chemistry
Avec: Prisca Lagardère , Romain Mustière , Nadia Amanzougaghene , Sébastien Hutter , Marion Casanova , Jean-François Franetich , Shahin Tajeri , Aurélie Malzert-Fréon , Sophie Corvaisier , Nadine Azas , Patrice Vanelle , Pierre Verhaeghe , Nicolas Primas , Dominique Mazier , Nicolas Masurier , Vincent Lisowski

Novel thienopyrimidones targeting hepatic and erythrocytic stages of Plasmodium parasites with increased microsomal stability.

European journal of medicinal chemistry
Avec: Prisca Lagardère , Romain Mustière , Nadia Amanzougaghene , Sébastien Hutter , Marion Casanova , Jean-François Franetich , Shahin Tajeri , Aurélie Malzert-Fréon , Sophie Corvaisier , Marc Since , Nadine Azas , Patrice Vanelle , Pierre Verhaeghe , Nicolas Primas , Dominique Mazier , Nicolas Masurier , Vincent Lisowski

A Biomimetic Multiparametric Assay to Characterise Anti-Amyloid Drugs.

International journal of molecular sciences
Avec: Willy Smeralda , Marc Since , Sophie Corvaisier , Dimitri Fayolle , Julien Cardin , Sylvain Duprey , Jean-Pierre Jourdan , Christophe Cullin , Aurélie Malzert-Freon

Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer's Disease.

Molecules (Basel, Switzerland)
Avec: François-Xavier Toublet , Cédric Lecoutey , Julien Lalut , Bérénice Hatat , Audrey Davis , Marc Since , Sophie Corvaisier , Thomas Freret , Jana Sopkova de Oliveira Santos , Sylvie Claeysen , Michel Boulouard , Patrick Dallemagne , Christophe Rochais

Microplate assay for lipophilicity determination using intrinsic fluorescence of drugs: Application to a promising anticancer lead, pyridoclax.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Avec: Willy Smeralda , Marc Since , Sophie Corvaisier , Rémi Legay , Anne-Sophie Voisin-Chiret , Aurélie Malzert-Freon

Pharmacotechnical Development of a Nasal Drug Delivery Composite Nanosystem Intended for Alzheimer's Disease Treatment.

Pharmaceutics
Avec: Thomas Adnet , Anne-Claire Groo , Céline Picard , Audrey Davis , Sophie Corvaisier , Marc Since , Frédéric Bounoure , Christophe Rochais , Loïc Le Pluart , Patrick Dallemagne , Aurélie Malzert-Fréon

Active Targeted Nanoemulsions for Repurposing of Tegaserod in Alzheimer's Disease Treatment.

Pharmaceutics
Avec: Line Séguy , Léna Guyon , Manon Maurel , Pascal Verdié , Audrey Davis , Sophie Corvaisier , Vincent Lisowski , Patrick Dallemagne , Anne-Claire Groo , Aurélie Malzert-Fréon

β-Amyloid peptide interactions with biomimetic membranes: A multiparametric characterization.

International journal of biological macromolecules
Avec: Willy Smeralda , Marc Since , Julien Cardin , Sophie Corvaisier , Sophie Lecomte , Christophe Cullin , Aurélie Malzert-Fréon

Fast Anxiolytic-Like Effect Observed in the Rat Conditioned Defensive Burying Test, after a Single Oral Dose of Natural Protein Extract Products.

Nutrients
Avec: Thomas Freret , Stacy Largilliere , Gerald Nee , Melanie Coolzaet , Sophie Corvaisier , Michel Boulouard

Réseau de co-auteurs

Marc Since 14 collaborations
Aurélie Malzert-Fréon 12 collaborations
Pierre Verhaeghe 7 collaborations
Sébastien Hutter 6 collaborations
Nicolas Primas 6 collaborations
Nadine Azas 6 collaborations
Patrice Vanelle 6 collaborations
Dominique Mazier 5 collaborations
Audrey Davis 5 collaborations
Thomas Freret 5 collaborations
Patrick Dallemagne 5 collaborations
Clotilde Boudot 4 collaborations
Sandra Bourgeade-Delmas 4 collaborations
Alix Sournia-Saquet 4 collaborations
Alexis Valentin 4 collaborations
Bertrand Courtioux 4 collaborations
Michel Boulouard 4 collaborations
Christophe Rochais 4 collaborations
Anne-Claire Groo 4 collaborations
Vincent Lisowski 4 collaborations
Caroline Castera-Ducros 3 collaborations
Emilie Pinault 3 collaborations
Romain Paoli-Lombardo 3 collaborations
Julien Pedron 3 collaborations
Jean-Luc Stigliani 3 collaborations
Susan Wyllie 3 collaborations
Alan H Fairlamb 3 collaborations
Alexandre Destere 3 collaborations
Pascal Rathelot 3 collaborations
Julien Lalut 3 collaborations
Cédric Lecoutey 3 collaborations
Sylvie Claeysen 3 collaborations
Line Séguy 3 collaborations
Aurélie Malzert-Freon 3 collaborations
Romain Mustière 3 collaborations
Prisca Lagardère 3 collaborations
Nadia Amanzougaghene 3 collaborations
Shahin Tajeri 3 collaborations
Jean-François Franetich 3 collaborations
Nicolas Masurier 3 collaborations
Willy Smeralda 3 collaborations
Cyril Fersing 2 collaborations
Jean-Yves Brossas 2 collaborations
Luc Paris 2 collaborations
François-Xavier Toublet 2 collaborations
Bérénice Hatat 2 collaborations
Florian Daressy 2 collaborations
Vincent Dumontet 2 collaborations
Marc Litaudon 2 collaborations
Cécile Apel 2 collaborations
Fanny Roussi 2 collaborations
Joëlle Wiels 2 collaborations
Aude Robert 2 collaborations
Jana Sopkova de Oliveira Santos 2 collaborations
Anne-Sophie Voisin-Chiret 2 collaborations
Marion Casanova 2 collaborations
Julien Cardin 2 collaborations
Christophe Cullin 2 collaborations
Line Seguy 1 collaboration
Élisa Boutet-Robinet 1 collaboration
Elisa Boutet-Robinet 1 collaboration
Antoine Tronnet 1 collaboration
Justine Bergé 1 collaboration
Colin Bonduelle 1 collaboration
Céline Deraeve 1 collaboration
Geneviève Pratviel 1 collaboration
Rachel Milne 1 collaboration
Jana Sopková-de Oliveira Santos 1 collaboration
Sophia Lahlil 1 collaboration
Emilie Duval 1 collaboration
Florence Gaven 1 collaboration
Stacy Largillière 1 collaboration
Gérald Née 1 collaboration
Romain Legrand 1 collaboration
Noëlle Callizot 1 collaboration
Martina De Pascale 1 collaboration
Domenico Iacopetta 1 collaboration
Véronique Vie 1 collaboration
Gilles Paboeuf 1 collaboration
Didier Hennequin 1 collaboration
Serge Perato 1 collaboration
Marcella De Giorgi 1 collaboration
Maria Stefania Sinicropi 1 collaboration
Jana Sopkova-De Oliveira Santos 1 collaboration
Pierre Courault 1 collaboration
Stéphane Emery 1 collaboration
Sofia Boudour 1 collaboration
Françoise Rochefort 1 collaboration
Alain Ruffion 1 collaboration
Claude Dussart 1 collaboration
Stéphane Corvaisier 1 collaboration
Lou Rizzolo 1 collaboration
Marianne Leger 1 collaboration
Mathilde Groussard 1 collaboration
Hervé Platel 1 collaboration
Valentine Bouet 1 collaboration
Pascale Schumann-Bard 1 collaboration
Youssef Kabri 1 collaboration
Amaya Azqueta 1 collaboration
Damián Muruzabal 1 collaboration
Carole Di Giorgio 1 collaboration
Viviana Dell'Orco 1 collaboration
Emilie Brenot 1 collaboration
Loëtitia Favre 1 collaboration
Sandy Desrat 1 collaboration
Dimitri Fayolle 1 collaboration
Sylvain Duprey 1 collaboration
Jean-Pierre Jourdan 1 collaboration
Rémi Legay 1 collaboration
Thomas Adnet 1 collaboration
Céline Picard 1 collaboration
Frédéric Bounoure 1 collaboration
Loïc Le Pluart 1 collaboration
Léna Guyon 1 collaboration
Manon Maurel 1 collaboration
Pascal Verdié 1 collaboration
Sophie Lecomte 1 collaboration
Stacy Largilliere 1 collaboration
Gerald Nee 1 collaboration
Melanie Coolzaet 1 collaboration