Matthew B Frieman

Affiliations
  • Department of Microbiology and Immunology, The University of Maryland School of Medicine, Baltimore, MD, United States. Electronic address: MFrieman@som.umaryland.edu.

Publications (50)

The continued epidemic threat of SARS-CoV-2 and implications for the future of global public health.

Current opinion in virology
Avec: Timothy P Sheahan ,

NVX-CoV2373 vaccine protects cynomolgus macaque upper and lower airways against SARS-CoV-2 challenge.

Vaccine
Avec: Mimi Guebre-Xabier , Nita Patel , Jing-Hui Tian , Bin Zhou , Sonia Maciejewski , Kristal Lam , Alyse D Portnoff , Michael J Massare , Pedro A Piedra , Larry Ellingsworth , Gregory Glenn , Gale Smith

Functional Landscape of SARS-CoV-2 Cellular Restriction.

bioRxiv : the preprint server for biology
Avec: Laura Martin-Sancho , Mary K Lewinski , Lars Pache , Charlotte A Stoneham , Xin Yin , Dexter Pratt , Christopher Churas , Sara B Rosenthal , Sophie Liu , Paul D De Jesus , Alan M O'Neill , Anshu P Gounder , Courtney Nguyen , Yuan Pu , Aaron L Oom , Lisa Miorin , Ariel Rodriguez-Frandsen , Matthew Urbanowski , Megan L Shaw , Max W Chang , Christopher Benner , Adolfo García-Sastre , Trey Ideker , Judd F Hultquist , John Guatelli , Sumit K Chanda

Selective Naked-Eye Detection of SARS-CoV-2 Mediated by N Gene Targeted Antisense Oligonucleotide Capped Plasmonic Nanoparticles.

ACS nano
Avec: Parikshit Moitra , Maha Alafeef , Ketan Dighe , Dipanjan Pan

A SARS-CoV-2 Delta Variant Case Manifesting as Extensive Placental Infection and Fetal Transmission.

Gynecologic and obstetric investigation
Avec: Wei-Bin Shen , Shifa Turan , Bingbing Wang , Liviu Cojocaru , Christopher Harman , James Logue , E Albert Reece , Peixin Yang

Pyrimidine biosynthesis inhibitors synergize with nucleoside analogs to block SARS-CoV-2 infection.

bioRxiv : the preprint server for biology
Avec: David C Schultz , Robert M Johnson , Kasirajan Ayyanathan , Jesse Miller , Kanupriya Whig , Brinda Kamalia , Mark Dittmar , Stuart Weston , Holly L Hammond , Carly Dillen , Lauren Castellana , Jae Seung Lee , Minghua Li , Emily Lee , Samuel Constant , Marc Ferrer , Christoph A Thaiss , Sara Cherry

SARS-CoV-2 variant spike and accessory gene mutations alter pathogenesis.

Proceedings of the National Academy of Sciences of the United States of America
Avec: Marisa E McGrath , Yong Xue , Carly Dillen , Lauren Oldfield , N Assad-Garcia , Jayshree Zaveri , Natasha Singh , Lauren Baracco , Louis J Taylor , Sanjay Vashee ,

2',3' cyclic-nucleotide 3'-phosphodiesterase (CNP) inhibits SARS-CoV-2 virion assembly by blocking infection-induced mitochondria depolarization.

bioRxiv : the preprint server for biology
Avec: James Logue , Victoria M Melville , Jeremy Ardanuy ,

Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance.

bioRxiv : the preprint server for biology
Avec: Timothy R O'Meara , Etsuro Nanishi , Marisa E McGrath , Soumik Barman , Danica Dong , Carly Dillen , Manisha Menon , Hyuk-Soo Seo , Sirano Dhe-Paganon , Robert K Ernst , Ofer Levy , David J Dowling

Immunogenicity and protection of a variant nanoparticle vaccine that confers broad neutralization against SARS-CoV-2 variants.

Nature communications
Avec: James Logue , Robert M Johnson , Nita Patel , Bin Zhou , Sonia Maciejewski , Bryant Foreman , Haixia Zhou , Alyse D Portnoff , Jing-Hui Tian , Asma Rehman , Marisa E McGrath , Robert E Haupt , Stuart M Weston , Lauren Baracco , Holly Hammond , Mimi Guebre-Xabier , Carly Dillen , M Madhangi , Ann M Greene , Michael J Massare , Greg M Glenn , Gale Smith ,

Functional landscape of SARS-CoV-2 cellular restriction.

Molecular cell
Avec: Laura Martin-Sancho , Mary K Lewinski , Lars Pache , Charlotte A Stoneham , Xin Yin , Mark E Becker , Dexter Pratt , Christopher Churas , Sara B Rosenthal , Sophie Liu , Stuart Weston , Paul D De Jesus , Alan M O'Neill , Anshu P Gounder , Courtney Nguyen , Yuan Pu , Heather M Curry , Aaron L Oom , Lisa Miorin , Ariel Rodriguez-Frandsen , Fan Zheng , Chunxiang Wu , Yong Xiong , Matthew Urbanowski , Megan L Shaw , Max W Chang , Christopher Benner , Thomas J Hope , Adolfo García-Sastre , Trey Ideker , Judd F Hultquist , John Guatelli , Sumit K Chanda

Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 in nonhuman primates following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination.

bioRxiv : the preprint server for biology
Avec: Matthew J Gorman , Nita Patel , Mimi Guebre-Xabier , Alex Zhu , Caroline Atyeo , Krista M Pullen , Carolin Loos , Yenny Goez-Gazi , Ricardo Carrion , Jing-Hui Tian , Dansu Yaun , Kathryn Bowman , Bin Zhou , Sonia Maciejewski , Marisa E McGrath , James Logue , David Montefiori , Colin Mann , Sharon Schendel , Fatima Amanat , Florian Krammer , Erica Ollmann Saphire , Douglas Lauffenburger , Ann M Greene , Alyse D Portnoff , Michael J Massare , Larry Ellingsworth , Gregory Glenn , Gale Smith , Galit Alter

Novel TLR4 adjuvant elicits protection against homologous and heterologous Influenza A infection.

Vaccine
Avec: Robert E Haupt , Erin M Harberts , Robert J Kitz , Shirin Strohmeier , Florian Krammer , Robert K Ernst ,

Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2.

Nature
Avec: David C Schultz , Robert M Johnson , Kasirajan Ayyanathan , Jesse Miller , Kanupriya Whig , Brinda Kamalia , Mark Dittmar , Stuart Weston , Holly L Hammond , Carly Dillen , Jeremy Ardanuy , Louis Taylor , Jae Seung Lee , Minghua Li , Emily Lee , Clarissa Shoffler , Christopher Petucci , Samuel Constant , Marc Ferrer , Christoph A Thaiss , Sara Cherry

mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant.

Communications biology
Avec: Etsuro Nanishi , Marisa E McGrath , Timothy R O'Meara , Soumik Barman , Jingyou Yu , Huahua Wan , Carly A Dillen , Manisha Menon , Hyuk-Soo Seo , Kijun Song , Andrew Z Xu , Luke Sebastian , Byron Brook , Anna-Nicole Bosco , Francesco Borriello , Robert K Ernst , Dan H Barouch , Sirano Dhe-Paganon , Ofer Levy , David J Dowling

The mRNA vaccine BNT162b2 demonstrates impaired T

Research square
Avec: Byron Brook , Benoit Fatou , Abhinav Kumar Checkervarty , Soumik Barman , Cali Sweitzer , Anna-Nicole Bosco , Amy C Sherman , Lindsey R Baden , Elena Morrocchi , Guzman Sanchez-Schmitz , Paolo Palma , Etsuro Nanishi , Timothy R O'Meara , Marisa E McGrath , Dheeraj Soni , Simon D van Haren , Al Ozonoff , Joann Diray-Arce , Hanno Steen , David J Dowling , Ofer Levy

Enhancing the protection of influenza virus vaccines with BECC TLR4 adjuvant in aged mice.

Scientific reports
Avec: Robert Haupt , Lauren Baracco , Erin M Harberts , Madhumathi Loganathan , Lucas J Kerstetter , Florian Krammer , Lynda Coughlan , Robert K Ernst ,

A neonatal mouse model characterizes transmissibility of SARS-CoV-2 variants and reveals a role for ORF8.

Nature communications
Avec: Bruno A Rodriguez-Rodriguez , Grace O Ciabattoni , Ralf Duerr , Ana M Valero-Jimenez , Stephen T Yeung , Keaton M Crosse , Austin R Schinlever , Lucie Bernard-Raichon , Joaquin Rodriguez Galvan , Marisa E McGrath , Sanjay Vashee , Yong Xue , Cynthia A Loomis , Kamal M Khanna , Ken Cadwell , Ludovic Desvignes , Mila B Ortigoza , Meike Dittmann

Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity.

bioRxiv : the preprint server for biology
Avec: Etsuro Nanishi , Francesco Borriello , Timothy R O'Meara , Marisa E McGrath , Yoshine Saito , Robert E Haupt , Hyuk-Soo Seo , Simon D van Haren , Byron Brook , Jing Chen , Joann Diray-Arce , Simon Doss-Gollin , Maria De Leon , Katherine Chew , Manisha Menon , Kijun Song , Andrew Z Xu , Timothy M Caradonna , Jared Feldman , Blake M Hauser , Aaron G Schmidt , Amy C Sherman , Lindsey R Baden , Robert K Ernst , Carly Dillen , Stuart M Weston , Robert M Johnson , Holly L Hammond , Romana Mayer , Allen Burke , Maria E Bottazzi , Peter J Hotez , Ulrich Strych , Aiquan Chang , Jingyou Yu , Dan H Barouch , Sirano Dhe-Paganon , Ivan Zanoni , Al Ozonoff , Ofer Levy , David J Dowling

Comorbid diabetes results in immune dysregulation and enhanced disease severity following MERS-CoV infection.

JCI insight
Avec: Kirsten A Kulcsar , Christopher M Coleman , Sarah E Beck ,

Phase 1-2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine.

The New England journal of medicine
Avec: Cheryl Keech , Gary Albert , Iksung Cho , Andreana Robertson , Patricia Reed , Susan Neal , Joyce S Plested , Mingzhu Zhu , Shane Cloney-Clark , Haixia Zhou , Gale Smith , Nita Patel , Robert E Haupt , James Logue , Marisa McGrath , Stuart Weston , Pedro A Piedra , Chinar Desai , Kathleen Callahan , Maggie Lewis , Patricia Price-Abbott , Neil Formica , Vivek Shinde , Louis Fries , Jason D Lickliter , Paul Griffin , Bethanie Wilkinson , Gregory M Glenn

Defining the risk of SARS-CoV-2 variants on immune protection.

Nature
Avec: Marciela M DeGrace , Elodie Ghedin , Florian Krammer , Alba Grifoni , Arghavan Alisoltani , Galit Alter , Rama R Amara , Ralph S Baric , Dan H Barouch , Jesse D Bloom , Louis-Marie Bloyet , Gaston Bonenfant , Adrianus C M Boon , Eli A Boritz , Debbie L Bratt , Traci L Bricker , Liliana Brown , William J Buchser , Juan Manuel Carreño , Liel Cohen-Lavi , Tamarand L Darling , Meredith E Davis-Gardner , Bethany L Dearlove , Han Di , Meike Dittmann , Nicole A Doria-Rose , Daniel C Douek , Christian Drosten , Venkata-Viswanadh Edara , Ali Ellebedy , Thomas P Fabrizio , Guido Ferrari , Will M Fischer , William C Florence , Ron A M Fouchier , John Franks , Adolfo García-Sastre , Adam Godzik , Ana Silvia Gonzalez-Reiche , Aubree Gordon , Bart L Haagmans , Peter J Halfmann , David D Ho , Michael R Holbrook , Yaoxing Huang , Sarah L James , Lukasz Jaroszewski , Trushar Jeevan , Robert M Johnson , Terry C Jones , Astha Joshi , Yoshihiro Kawaoka , Lisa Kercher , Marion P G Koopmans , Bette Korber , Eilay Koren , Richard A Koup , Eric B LeGresley , Jacob E Lemieux , Mariel J Liebeskind , Zhuoming Liu , Brandi Livingston , James P Logue , Yang Luo , Adrian B McDermott , Margaret J McElrath , Victoria A Meliopoulos , Vineet D Menachery , David C Montefiori , Barbara Mühlemann , Vincent J Munster , Jenny E Munt , Manoj S Nair , Antonia Netzl , Anna M Niewiadomska , Sijy O'Dell , Andrew Pekosz , Stanley Perlman , Marjorie C Pontelli , Barry Rockx , Morgane Rolland , Paul W Rothlauf , Sinai Sacharen , Richard H Scheuermann , Stephen D Schmidt , Michael Schotsaert , Stacey Schultz-Cherry , Robert A Seder , Mayya Sedova , Alessandro Sette , Reed S Shabman , Xiaoying Shen , Pei-Yong Shi , Maulik Shukla , Viviana Simon , Spencer Stumpf , Nancy J Sullivan , Larissa B Thackray , James Theiler , Paul G Thomas , Sanja Trifkovic , Sina Türeli , Samuel A Turner , Maria A Vakaki , Harm van Bakel , Laura A VanBlargan , Leah R Vincent , Zachary S Wallace , Li Wang , Maple Wang , Pengfei Wang , Wei Wang , Scott C Weaver , Richard J Webby , Carol D Weiss , David E Wentworth , Stuart M Weston , Sean P J Whelan , Bradley M Whitener , Samuel H Wilks , Xuping Xie , Baoling Ying , Hyejin Yoon , Bin Zhou , Tomer Hertz , Derek J Smith , Michael S Diamond , Diane J Post , Mehul S Suthar

SARS-CoV-2 invades cognitive centers of the brain and induces Alzheimer's-like neuropathology.

bioRxiv : the preprint server for biology
Avec: Wei-Bin Shen , Montasir Elahi , James Logue , Penghua Yang , Lauren Baracco , E Albert Reece , Bingbing Wang , Ling Li , Thomas G Blanchard , Zhe Han , Robert A Rissman , Peixin Yang

SARS-CoV-2 ORF8 modulates lung inflammation and clinical disease progression.

PLoS pathogens
Avec: Marisa E McGrath , Yong Xue , Louis Taylor , Carly Dillen , Jeremy Ardanuy , Norberto Gonzalez-Juarbe , Lauren Baracco , Raymond Kim , Rebecca Hart , Nacyra Assad-Garcia , Sanjay Vashee ,

Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance.

The Journal of allergy and clinical immunology
Avec: Timothy R O'Meara , Etsuro Nanishi , Marisa E McGrath , Soumik Barman , Danica Dong , Carly Dillen , Manisha Menon , Hyuk-Soo Seo , Sirano Dhe-Paganon , Robert K Ernst , Ofer Levy , David J Dowling

CNP blocks mitochondrial depolarization and inhibits SARS-CoV-2 replication in vitro and in vivo.

PLoS pathogens
Avec: James Logue , Victoria M Melville , Jeremy Ardanuy ,

A Yeast Suppressor Screen Used To Identify Mammalian SIRT1 as a Proviral Factor for Middle East Respiratory Syndrome Coronavirus Replication.

Journal of virology
Avec: Stuart Weston , Krystal L Matthews , Rachel Lent , Alexandra Vlk , Rob Haupt , Tami Kingsbury ,

Broad Anti-coronavirus Activity of Food and Drug Administration-Approved Drugs against SARS-CoV-2

Journal of virology
Avec: Stuart Weston , Christopher M Coleman , Robert Haupt , James Logue , Krystal Matthews , Yize Li , Hanako M Reyes , Susan R Weiss ,

COVID-19: Knowns, Unknowns, and Questions.

mSphere
Avec: Stuart Weston ,

An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice.

Science translational medicine
Avec: Etsuro Nanishi , Francesco Borriello , Timothy R O'Meara , Marisa E McGrath , Yoshine Saito , Robert E Haupt , Hyuk-Soo Seo , Simon D van Haren , Cecilia B Cavazzoni , Byron Brook , Soumik Barman , Jing Chen , Joann Diray-Arce , Simon Doss-Gollin , Maria De Leon , Alejandra Prevost-Reilly , Katherine Chew , Manisha Menon , Kijun Song , Andrew Z Xu , Timothy M Caradonna , Jared Feldman , Blake M Hauser , Aaron G Schmidt , Amy C Sherman , Lindsey R Baden , Robert K Ernst , Carly Dillen , Stuart M Weston , Robert M Johnson , Holly L Hammond , Romana Mayer , Allen Burke , Maria E Bottazzi , Peter J Hotez , Ulrich Strych , Aiquan Chang , Jingyou Yu , Peter T Sage , Dan H Barouch , Sirano Dhe-Paganon , Ivan Zanoni , Al Ozonoff , Ofer Levy , David J Dowling

Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M vaccination.

Cell reports. Medicine
Avec: Matthew J Gorman , Nita Patel , Mimi Guebre-Xabier , Alex L Zhu , Caroline Atyeo , Krista M Pullen , Carolin Loos , Yenny Goez-Gazi , Ricardo Carrion , Jing-Hui Tian , Dansu Yuan , Kathryn A Bowman , Bin Zhou , Sonia Maciejewski , Marisa E McGrath , James Logue , David Montefiori , Colin Mann , Sharon Schendel , Fatima Amanat , Florian Krammer , Erica Ollmann Saphire , Douglas A Lauffenburger , Ann M Greene , Alyse D Portnoff , Michael J Massare , Larry Ellingsworth , Gregory Glenn , Gale Smith , Galit Alter

Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail.

Nature microbiology
Avec: Jinhui Dong , Seth J Zost , Allison J Greaney , Tyler N Starr , Adam S Dingens , Elaine C Chen , Rita E Chen , James Brett Case , Rachel E Sutton , Pavlo Gilchuk , Jessica Rodriguez , Erica Armstrong , Christopher Gainza , Rachel S Nargi , Elad Binshtein , Xuping Xie , Xianwen Zhang , Pei-Yong Shi , James Logue , Stuart Weston , Marisa E McGrath , Tyler Brady , Kevin M Tuffy , Helen Bright , Yueh-Ming Loo , Patrick M McTamney , Mark T Esser , Robert H Carnahan , Michael S Diamond , Jesse D Bloom , James E Crowe

The SKI complex is a broad-spectrum, host-directed antiviral drug target for coronaviruses, influenza, and filoviruses.

Proceedings of the National Academy of Sciences of the United States of America
Avec: Stuart Weston , Lauren Baracco , Chloe Keller , Krystal Matthews , Marisa E McGrath , James Logue , Janie Liang , Julie Dyall , Michael R Holbrook , Lisa E Hensley , Peter B Jahrling , Wenbo Yu , Alexander D MacKerell ,

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

Science (New York, N.Y.)
Avec: David E Gordon , Joseph Hiatt , Mehdi Bouhaddou , Veronica V Rezelj , Svenja Ulferts , Hannes Braberg , Alexander S Jureka , Kirsten Obernier , Jeffrey Z Guo , Jyoti Batra , Robyn M Kaake , Andrew R Weckstein , Tristan W Owens , Meghna Gupta , Sergei Pourmal , Erron W Titus , Merve Cakir , Margaret Soucheray , Michael McGregor , Zeynep Cakir , Gwendolyn Jang , Matthew J O'Meara , Tia A Tummino , Ziyang Zhang , Helene Foussard , Ajda Rojc , Yuan Zhou , Dmitry Kuchenov , Ruth Hüttenhain , Jiewei Xu , Manon Eckhardt , Danielle L Swaney , Jacqueline M Fabius , Manisha Ummadi , Beril Tutuncuoglu , Ujjwal Rathore , Maya Modak , Paige Haas , Kelsey M Haas , Zun Zar Chi Naing , Ernst H Pulido , Ying Shi , Inigo Barrio-Hernandez , Danish Memon , Eirini Petsalaki , Alistair Dunham , Miguel Correa Marrero , David Burke , Cassandra Koh , Thomas Vallet , Jesus A Silvas , Caleigh M Azumaya , Christian Billesbølle , Axel F Brilot , Melody G Campbell , Amy Diallo , Miles Sasha Dickinson , Devan Diwanji , Nadia Herrera , Nick Hoppe , Huong T Kratochvil , Yanxin Liu , Gregory E Merz , Michelle Moritz , Henry C Nguyen , Carlos Nowotny , Cristina Puchades , Alexandrea N Rizo , Ursula Schulze-Gahmen , Amber M Smith , Ming Sun , Iris D Young , Jianhua Zhao , Daniel Asarnow , Justin Biel , Alisa Bowen , Julian R Braxton , Jen Chen , Cynthia M Chio , Un Seng Chio , Ishan Deshpande , Loan Doan , Bryan Faust , Sebastian Flores , Mingliang Jin , Kate Kim , Victor L Lam , Fei Li , Junrui Li , Yen-Li Li , Yang Li , Xi Liu , Megan Lo , Kyle E Lopez , Arthur A Melo , Frank R Moss , Phuong Nguyen , Joana Paulino , Komal Ishwar Pawar , Jessica K Peters , Thomas H Pospiech , Maliheh Safari , Smriti Sangwan , Kaitlin Schaefer , Paul V Thomas , Aye C Thwin , Raphael Trenker , Eric Tse , Tsz Kin Martin Tsui , Feng Wang , Natalie Whitis , Zanlin Yu , Kaihua Zhang , Yang Zhang , Fengbo Zhou , Daniel Saltzberg , Auteur inconnu , Anthony J Hodder , Amber S Shun-Shion , Daniel M Williams , Kris M White , Romel Rosales , Thomas Kehrer , Lisa Miorin , Elena Moreno , Arvind H Patel , Suzannah Rihn , Mir M Khalid , Albert Vallejo-Gracia , Parinaz Fozouni , Camille R Simoneau , Theodore L Roth , David Wu , Mohd Anisul Karim , Maya Ghoussaini , Ian Dunham , Francesco Berardi , Sebastian Weigang , Maxime Chazal , Jisoo Park , James Logue , Marisa McGrath , Stuart Weston , Robert Haupt , C James Hastie , Matthew Elliott , Fiona Brown , Kerry A Burness , Elaine Reid , Mark Dorward , Clare Johnson , Stuart G Wilkinson , Anna Geyer , Daniel M Giesel , Carla Baillie , Samantha Raggett , Hannah Leech , Rachel Toth , Nicola Goodman , Kathleen C Keough , Abigail L Lind , Auteur inconnu , Reyna J Klesh , Kafi R Hemphill , Jared Carlson-Stevermer , Jennifer Oki , Kevin Holden , Travis Maures , Katherine S Pollard , Andrej Sali , David A Agard , Yifan Cheng , James S Fraser , Adam Frost , Natalia Jura , Tanja Kortemme , Aashish Manglik , Daniel R Southworth , Robert M Stroud , Dario R Alessi , Paul Davies , Trey Ideker , Carmen Abate , Nolwenn Jouvenet , Georg Kochs , Brian Shoichet , Melanie Ott , Massimo Palmarini , Kevan M Shokat , Adolfo García-Sastre , Jeremy A Rassen , Robert Grosse , Oren S Rosenberg , Kliment A Verba , Christopher F Basler , Marco Vignuzzi , Andrew A Peden , Pedro Beltrao , Nevan J Krogan

Discovery of a Novel Inhibitor of Coronavirus 3CL Protease for the Potential Treatment of COVID-19.

bioRxiv : the preprint server for biology
Avec: Britton Boras , Rhys M Jones , Brandon J Anson , Dan Arenson , Lisa Aschenbrenner , Malina A Bakowski , Nathan Beutler , Joseph Binder , Emily Chen , Heather Eng , Holly Hammond , Jennifer Hammond , Robert E Haupt , Robert Hoffman , Eugene P Kadar , Rob Kania , Emi Kimoto , Melanie G Kirkpatrick , Lorraine Lanyon , Emma K Lendy , Jonathan R Lillis , James Logue , Suman A Luthra , Chunlong Ma , Stephen W Mason , Marisa E McGrath , Stephen Noell , R Scott Obach , Matthew N O'Brien , Rebecca O'Connor , Kevin Ogilvie , Dafydd Owen , Martin Pettersson , Matthew R Reese , Thomas F Rogers , Michelle I Rossulek , Jean G Sathish , Norimitsu Shirai , Claire Steppan , Martyn Ticehurst , Lawrence W Updyke , Stuart Weston , Yuao Zhu , Jun Wang , Arnab K Chatterjee , Andrew D Mesecar , Annaliesa S Anderson , Charlotte Allerton

Phage-like particle vaccines are highly immunogenic and protect against pathogenic coronavirus infection and disease.

NPJ vaccines
Avec: Bennett J Davenport , Alexis Catala , Stuart M Weston , Robert M Johnson , Jeremy Ardanuy , Holly L Hammond , Carly Dillen , Carlos E Catalano , Thomas E Morrison

PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19.

Communications biology
Avec: James Logue , Arup R Chakraborty , Robert Johnson , Girija Goyal , Melissa Rodas , Louis J Taylor , Lauren Baracco , Marisa E McGrath , Robert Haupt , Brooke A Furlong , Mercy Soong , Pranav Prabhala , Viktor Horvath , Kenneth E Carlson , Stuart Weston , Donald E Ingber , Melvin L DePamphilis ,

Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq.

Nature communications
Avec: Sara Sunshine , Andreas S Puschnik , Joseph M Replogle , Matthew T Laurie , Jamin Liu , Beth Shoshana Zha , James K Nuñez , Janie R Byrum , Aidan H McMorrow , Juliane Winkler , Xiaojie Qiu , Oren S Rosenberg , Manuel D Leonetti , Chun Jimmie Ye , Jonathan S Weissman , Joseph L DeRisi , Marco Y Hein

Oral pharmacokinetics and efficacy of oral phospholipid remdesivir nucleoside prodrugs against SARS-CoV-2 in mice.

Antimicrobial agents and chemotherapy
Avec: Aaron F Carlin , James R Beadle , Jeremy Ardanuy , Alex E Clark , Victoria Rhodes , Aaron F Garretson , Joyce A Murphy , Nadejda Valiaeva , Robert T Schooley , Karl Y Hostetler

Viral RNA and Infectious Influenza Virus on Mobile Phones of Patients With Influenza in Hong Kong and the United States.

The Journal of infectious diseases
Avec: Jingyi Xiao , P Jacob Bueno de Mesquita , Nancy H L Leung , Oluwasanmi Adenaiye , Sheldon Tai , Filbert Hong , Daniel K W Chu , Dennis K M Ip , Benjamin J Cowling , Donald K Milton

Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19.

Nature communications
Avec: Britton Boras , Rhys M Jones , Brandon J Anson , Dan Arenson , Lisa Aschenbrenner , Malina A Bakowski , Nathan Beutler , Joseph Binder , Emily Chen , Heather Eng , Holly Hammond , Jennifer Hammond , Robert E Haupt , Robert Hoffman , Eugene P Kadar , Rob Kania , Emi Kimoto , Melanie G Kirkpatrick , Lorraine Lanyon , Emma K Lendy , Jonathan R Lillis , James Logue , Suman A Luthra , Chunlong Ma , Stephen W Mason , Marisa E McGrath , Stephen Noell , R Scott Obach , Matthew N O' Brien , Rebecca O'Connor , Kevin Ogilvie , Dafydd Owen , Martin Pettersson , Matthew R Reese , Thomas F Rogers , Romel Rosales , Michelle I Rossulek , Jean G Sathish , Norimitsu Shirai , Claire Steppan , Martyn Ticehurst , Lawrence W Updyke , Stuart Weston , Yuao Zhu , Kris M White , Adolfo García-Sastre , Jun Wang , Arnab K Chatterjee , Andrew D Mesecar , Annaliesa S Anderson , Charlotte Allerton

Antibodies elicited by SARS-CoV-2 infection or mRNA vaccines have reduced neutralizing activity against Beta and Omicron pseudoviruses.

Science translational medicine
Avec: Benjamin L Sievers , Saborni Chakraborty , Yong Xue , Terri Gelbart , Joseph C Gonzalez , Arianna G Cassidy , Yarden Golan , Mary Prahl , Stephanie L Gaw , Prabhu S Arunachalam , Catherine A Blish , Scott D Boyd , Mark M Davis , Prasanna Jagannathan , Kari C Nadeau , Bali Pulendran , Upinder Singh , Richard H Scheuermann , Sanjay Vashee , Taia T Wang , Gene S Tan

SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 immunogenicity in baboons and protection in mice.

Nature communications
Avec: Jing-Hui Tian , Nita Patel , Robert Haupt , Haixia Zhou , Stuart Weston , Holly Hammond , James Logue , Alyse D Portnoff , James Norton , Mimi Guebre-Xabier , Bin Zhou , Kelsey Jacobson , Sonia Maciejewski , Rafia Khatoon , Malgorzata Wisniewska , Will Moffitt , Stefanie Kluepfel-Stahl , Betty Ekechukwu , James Papin , Sarathi Boddapati , C Jason Wong , Pedro A Piedra , Michael J Massare , Louis Fries , Karin Lövgren Bengtsson , Linda Stertman , Larry Ellingsworth , Gregory Glenn , Gale Smith

Animal models for COVID-19.

Nature
Avec: César Muñoz-Fontela , William E Dowling , Simon G P Funnell , Pierre-S Gsell , A Ximena Riveros-Balta , Randy A Albrecht , Hanne Andersen , Ralph S Baric , Miles W Carroll , Marco Cavaleri , Chuan Qin , Ian Crozier , Kai Dallmeier , Leon de Waal , Emmie de Wit , Leen Delang , Erik Dohm , W Paul Duprex , Darryl Falzarano , Courtney L Finch , Barney S Graham , Lisa E Gralinski , Kate Guilfoyle , Bart L Haagmans , Geraldine A Hamilton , Amy L Hartman , Sander Herfst , Suzanne J F Kaptein , William B Klimstra , Ivana Knezevic , Philip R Krause , Jens H Kuhn , Roger Le Grand , Mark G Lewis , Wen-Chun Liu , Pauline Maisonnasse , Anita K McElroy , Vincent Munster , Nadia Oreshkova , Angela L Rasmussen , Joana Rocha-Pereira , Barry Rockx , Estefanía Rodríguez , Thomas F Rogers , Francisco J Salguero , Michael Schotsaert , Koert J Stittelaar , Hendrik Jan Thibaut , Chien-Te Tseng , Júlia Vergara-Alert , Martin Beer , Trevor Brasel , Jasper F W Chan , Adolfo García-Sastre , Johan Neyts , Stanley Perlman , Douglas S Reed , Juergen A Richt , Chad J Roy , Joaquim Segalés , Seshadri S Vasan , Ana María Henao-Restrepo , Dan H Barouch

Safety and immunogenicity following a homologous booster dose of a SARS-CoV-2 recombinant spike protein vaccine (NVX-CoV2373): a secondary analysis of a randomised, placebo-controlled, phase 2 trial.

The Lancet. Infectious diseases
Avec: Raburn M Mallory , Neil Formica , Susan Pfeiffer , Bethanie Wilkinson , Alex Marcheschi , Gary Albert , Heather McFall , Michelle Robinson , Joyce S Plested , Mingzhu Zhu , Shane Cloney-Clark , Bin Zhou , Gordon Chau , Andreana Robertson , Sonia Maciejewski , Holly L Hammond , Lauren Baracco , James Logue , Gale Smith , Nita Patel , Gregory M Glenn , Auteur inconnu

Mucosal and Systemic Responses to Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination Determined by Severity of Primary Infection.

mSphere
Avec: Mohammad M Sajadi , Amber Myers , James Logue , Saman Saadat , Narjes Shokatpour , James Quinn , Michelle Newman , Meagan Deming , Zahra Rikhtegaran Tehrani , Laurence S Magder , Maryam Karimi , Abdolrahim Abbasi , Mike Shlyak , Lauren Baracco , Shane Crotty , Anthony D Harris

Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice.

NPJ vaccines
Avec: Etsuro Nanishi , Francesco Borriello , Hyuk-Soo Seo , Timothy R O'Meara , Marisa E McGrath , Yoshine Saito , Jing Chen , Joann Diray-Arce , Kijun Song , Andrew Z Xu , Soumik Barman , Manisha Menon , Danica Dong , Timothy M Caradonna , Jared Feldman , Blake M Hauser , Aaron G Schmidt , Lindsey R Baden , Robert K Ernst , Carly Dillen , Jingyou Yu , Aiquan Chang , Luuk Hilgers , Peter Paul Platenburg , Sirano Dhe-Paganon , Dan H Barouch , Al Ozonoff , Ivan Zanoni , David J Dowling , Ofer Levy

Dipeptidyl Peptidase 4/Midline-1 Axis Promotes T Lymphocyte Motility in Atherosclerosis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Avec: Xiaoquan Rao , Michael Razavi , Georgeta Mihai , Yingying Wei , Zachary Braunstein , Xiao Jian Sun , Quan Gong , Jun Chen , Gang Zhao , Zheng Liu , Michael J Quon , Lingli Dong , Sanjay Rajagopalan , Jixin Zhong

SARS-CoV-2 ORF6 protein does not antagonize interferon signaling in respiratory epithelial Calu-3 cells during infection.

mBio
Avec: Minghua Li , Kasirajan Ayyanathan , Mark Dittmar , Jesse Miller , Iulia Tapescu , Jae Seung Lee , Marisa E McGrath , Yong Xue , Sanjay Vashee , David C Schultz , Sara Cherry

Placental SARS-CoV-2 infection and its implications for increased risk of adverse pregnancy outcomes.

American journal of perinatology
Avec: Bingbing Wang , Wei-Bin Shen , Courtney Townsel , Lauren Baracco , James Logue , E Albert Reece , Peixin Yang

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James Logue 19 collaborations
Marisa E McGrath 19 collaborations
Stuart Weston 14 collaborations
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