Jeremy R Keown

Affiliations

School of Biological Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand.

ORCID: 0000-0003-0159-9257

Publications (24)

The RING domain of TRIM69 promotes higher-order assembly.

Acta crystallographica. Section D, Structural biology

Avec: Joy Yang , Moyra M Black , David C Goldstone

Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins.

Nature communications

Avec: Max Renner , Wanwisa Dejnirattisai , Loïc Carrique , Itziar Serna Martin , Dimple Karia , Serban L Ilca , Shu F Ho , Abhay Kotecha , Juthathip Mongkolsapaya , Gavin R Screaton , Jonathan M Grimes

Crystal structure of protein tyrosine phosphatase-2 from Cydia pomonella granulovirus.

Acta crystallographica. Section F, Structural biology communications

Avec: Guangmei Huang , Michael R Oliver , David C Goldstone , Peter Metcalf

A method for analyzing the composition of viral nucleoprotein complexes, produced by heterologous expression in bacteria.

Virology

Avec: Melissa N Webby , Matthew P Sullivan , Kavestri M Yegambaram , Mazdak Radjainia , Richard L Kingston

Structure of an H3N2 influenza virus nucleoprotein.

Acta crystallographica. Section F, Structural biology communications

Avec: Michael L Knight , Haitian Fan , David L V Bauer , Jonathan M Grimes , Ervin Fodor ,

Characterization of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification.

Nucleic acids research

Avec: Hannah T Baddock , Sanja Brolih , Yuliana Yosaatmadja , Malitha Ratnaweera , Marcin Bielinski , Lonnie P Swift , Abimael Cruz-Migoni , Haitian Fan , Alexander P Walker , Garrett M Morris , Jonathan M Grimes , Ervin Fodor , Christopher J Schofield , Opher Gileadi , Peter J McHugh

A structural understanding of influenza virus genome replication.

Trends in microbiology

Avec: Zihan Zhu , Ervin Fodor ,

Design, Synthesis, and Biological Evaluation of Novel Indoles Targeting the Influenza PB2 Cap Binding Region.

Journal of medicinal chemistry

Avec: David C McGowan , Wendy Balemans , Werner Embrechts , Magali Motte , Christophe Buyck , Jordi Corbera , Mario Funes , Laura Moreno , Ludwig Cooymans , Abdellah Tahri , Julien Eymard , Bart Stoops , Rudy Strijbos , Joke Van den Berg , Ervin Fodor , Jonathan M Grimes , Anil Koul , Tim H M Jonckers , Pierre Raboisson , Jérôme Guillemont

Structures of influenza A virus RNA polymerase offer insight into viral genome replication.

Nature

Avec: Haitian Fan , Alexander P Walker , Loïc Carrique , Itziar Serna Martin , Dimple Karia , Jane Sharps , Narin Hengrung , Els Pardon , Jan Steyaert , Jonathan M Grimes , Ervin Fodor

Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.

Nature communications

Avec: Zihan Zhu , Loïc Carrique , Haitian Fan , Alexander P Walker , Itziar Serna Martin , Els Pardon , Jan Steyaert , Ervin Fodor , Jonathan M Grimes

Structural Analysis of the Menangle Virus P Protein Reveals a Soft Boundary between Ordered and Disordered Regions.

Viruses

Avec: Melissa N Webby , Nicole Herr , Esther M M Bulloch , Michael Schmitz , David C Goldstone , Richard L Kingston

Structural and biophysical characterization of the Borna disease virus 1 phosphoprotein.

Acta crystallographica. Section F, Structural biology communications

Avec: Jack D Whitehead , Jonathan M Grimes ,

NlpC/P60 peptidoglycan hydrolases of Trichomonas vaginalis have complementary activities that empower the protozoan to control host-protective lactobacilli.

PLoS pathogens

Avec: Michael J Barnett , Jully Pinheiro , Jacob Biboy , Joe Gray , Ioana-Wilhelmina Lucinescu , Waldemar Vollmer , Robert P Hirt , Augusto Simoes-Barbosa , David C Goldstone

Atomic structure of a nudivirus occlusion body protein determined from a 70-year-old crystal sample.

Nature communications

Avec: Adam D Crawshaw , Jose Trincao , Loïc Carrique , Richard J Gildea , Sam Horrell , Anna J Warren , Danny Axford , Robin Owen , Gwyndaf Evans , Annie Bézier , Peter Metcalf , Jonathan M Grimes

A Dissection of Oligomerization by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family.

Journal of molecular biology

Avec: Yunyuan Sun , Moyra M Black , Charlène Raclot , Nicholas Demarais , Didier Trono , Priscilla Turelli , David C Goldstone

The SARS-CoV-2 RNA polymerase is a viral RNA capping enzyme.

Nucleic acids research

Avec: Alexander P Walker , Haitian Fan , Michael L Knight , Jonathan M Grimes , Ervin Fodor

Publisher Correction: Parallel evolution in the emergence of highly pathogenic avian influenza A viruses.

Nature communications

Avec: Marina Escalera-Zamudio , Michael Golden , Bernardo Gutiérrez , Julien Thézé , Jeremy Russell Keown , Loic Carrique , Thomas A Bowden , Oliver G Pybus

Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix.

Nature communications

Avec: Michael R Oliver , Christopher R Horne , Safal Shrestha , Lung-Yu Liang , Samuel N Young , Jarrod J Sandow , Andrew I Webb , David C Goldstone , Isabelle S Lucet , Natarajan Kannan , Peter Metcalf , James M Murphy

Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation.

Nature communications

Avec: Ecco Staller , Loïc Carrique , Olivia C Swann , Haitian Fan , Carol M Sheppard , Wendy S Barclay , Jonathan M Grimes , Ervin Fodor

Protein target highlights in CASP15: Analysis of models by structure providers.

Proteins

Avec: Leila T Alexander , Janani Durairaj , Andriy Kryshtafovych , Luciano A Abriata , Yusupha Bayo , Gira Bhabha , Cécile Breyton , Simon G Caulton , James Chen , Séraphine Degroux , Damian C Ekiert , Benedikte S Erlandsen , Peter L Freddolino , Dominic Gilzer , Chris Greening , Jonathan M Grimes , Rhys Grinter , Manickam Gurusaran , Marcus D Hartmann , Charlie J Hitchman , Ashleigh Kropp , Petri Kursula , Andrew L Lovering , Bruno Lemaitre , Andrea Lia , Shiheng Liu , Maria Logotheti , Shuze Lu , Sigurbjörn Markússon , Mitchell D Miller , George Minasov , Hartmut H Niemann , Felipe Opazo , George N Phillips , Owen R Davies , Samuel Rommelaere , Monica Rosas-Lemus , Pietro Roversi , Karla Satchell , Nathan Smith , Mark A Wilson , Kuan-Lin Wu , Xian Xia , Han Xiao , Wenhua Zhang , Z Hong Zhou , Krzysztof Fidelis , Maya Topf , John Moult , Torsten Schwede

Enisamium is a small molecule inhibitor of the influenza A virus and SARS-CoV-2 RNA polymerases.

bioRxiv : the preprint server for biology

Avec: Alexander P Walker , Haitian Fan , Victor Margitich , Jonathan M Grimes , Ervin Fodor , Aartjan J W Te Velthuis

Host ANP32A mediates the assembly of the influenza virus replicase.

Nature

Avec: Loïc Carrique , Haitian Fan , Alexander P Walker , Jane Sharps , Ecco Staller , Wendy S Barclay , Ervin Fodor , Jonathan M Grimes

Parallel evolution in the emergence of highly pathogenic avian influenza A viruses.

Nature communications

Avec: Marina Escalera-Zamudio , Michael Golden , Bernardo Gutiérrez , Julien Thézé , Jeremy Russell Keown , Loic Carrique , Thomas A Bowden , Oliver G Pybus

The C-Terminal Domains of the PB2 Subunit of the Influenza A Virus RNA Polymerase Directly Interact with Cellular GTPase Rab11a.

Journal of virology

Avec: Hana Veler , Haitian Fan , Jane Sharps , Marjorie Fournier , Jonathan M Grimes , Ervin Fodor

Réseau de co-auteurs

Jonathan M Grimes 14 collaborations

Ervin Fodor 11 collaborations

Haitian Fan 9 collaborations

David C Goldstone 6 collaborations

Loïc Carrique 6 collaborations

Alexander P Walker 6 collaborations

Itziar Serna Martin 3 collaborations

Peter Metcalf 3 collaborations

Jane Sharps 3 collaborations

Moyra M Black 2 collaborations

Dimple Karia 2 collaborations

Michael R Oliver 2 collaborations

Melissa N Webby 2 collaborations

Richard L Kingston 2 collaborations

Michael L Knight 2 collaborations

Zihan Zhu 2 collaborations

Els Pardon 2 collaborations

Jan Steyaert 2 collaborations

Marina Escalera-Zamudio 2 collaborations

Michael Golden 2 collaborations

Bernardo Gutiérrez 2 collaborations

Julien Thézé 2 collaborations

Jeremy Russell Keown 2 collaborations

Loic Carrique 2 collaborations

Thomas A Bowden 2 collaborations

Oliver G Pybus 2 collaborations

Ecco Staller 2 collaborations

Wendy S Barclay 2 collaborations

Joy Yang 1 collaboration

Max Renner 1 collaboration

Wanwisa Dejnirattisai 1 collaboration

Serban L Ilca 1 collaboration

Shu F Ho 1 collaboration

Abhay Kotecha 1 collaboration

Juthathip Mongkolsapaya 1 collaboration

Gavin R Screaton 1 collaboration

Guangmei Huang 1 collaboration

Matthew P Sullivan 1 collaboration

Kavestri M Yegambaram 1 collaboration

Mazdak Radjainia 1 collaboration

David L V Bauer 1 collaboration

Hannah T Baddock 1 collaboration

Sanja Brolih 1 collaboration

Yuliana Yosaatmadja 1 collaboration

Malitha Ratnaweera 1 collaboration

Marcin Bielinski 1 collaboration

Lonnie P Swift 1 collaboration

Abimael Cruz-Migoni 1 collaboration

Garrett M Morris 1 collaboration

Christopher J Schofield 1 collaboration

Opher Gileadi 1 collaboration

Peter J McHugh 1 collaboration

David C McGowan 1 collaboration

Wendy Balemans 1 collaboration

Werner Embrechts 1 collaboration

Magali Motte 1 collaboration

Christophe Buyck 1 collaboration

Jordi Corbera 1 collaboration

Mario Funes 1 collaboration

Laura Moreno 1 collaboration

Ludwig Cooymans 1 collaboration

Abdellah Tahri 1 collaboration

Julien Eymard 1 collaboration

Bart Stoops 1 collaboration

Rudy Strijbos 1 collaboration

Joke Van den Berg 1 collaboration

Anil Koul 1 collaboration

Tim H M Jonckers 1 collaboration

Pierre Raboisson 1 collaboration

Jérôme Guillemont 1 collaboration

Narin Hengrung 1 collaboration

Nicole Herr 1 collaboration

Esther M M Bulloch 1 collaboration

Michael Schmitz 1 collaboration

Jack D Whitehead 1 collaboration

Michael J Barnett 1 collaboration

Jully Pinheiro 1 collaboration

Jacob Biboy 1 collaboration

Joe Gray 1 collaboration

Ioana-Wilhelmina Lucinescu 1 collaboration

Waldemar Vollmer 1 collaboration

Robert P Hirt 1 collaboration

Augusto Simoes-Barbosa 1 collaboration

Adam D Crawshaw 1 collaboration

Jose Trincao 1 collaboration

Richard J Gildea 1 collaboration

Sam Horrell 1 collaboration

Anna J Warren 1 collaboration

Danny Axford 1 collaboration

Robin Owen 1 collaboration

Gwyndaf Evans 1 collaboration

Annie Bézier 1 collaboration

Yunyuan Sun 1 collaboration

Charlène Raclot 1 collaboration

Nicholas Demarais 1 collaboration

Didier Trono 1 collaboration

Priscilla Turelli 1 collaboration

Christopher R Horne 1 collaboration

Safal Shrestha 1 collaboration

Lung-Yu Liang 1 collaboration

Samuel N Young 1 collaboration

Jarrod J Sandow 1 collaboration

Andrew I Webb 1 collaboration

Isabelle S Lucet 1 collaboration

Natarajan Kannan 1 collaboration

James M Murphy 1 collaboration

Olivia C Swann 1 collaboration

Carol M Sheppard 1 collaboration

Leila T Alexander 1 collaboration

Janani Durairaj 1 collaboration

Andriy Kryshtafovych 1 collaboration

Luciano A Abriata 1 collaboration

Yusupha Bayo 1 collaboration

Gira Bhabha 1 collaboration

Cécile Breyton 1 collaboration

Simon G Caulton 1 collaboration

James Chen 1 collaboration

Séraphine Degroux 1 collaboration

Damian C Ekiert 1 collaboration

Benedikte S Erlandsen 1 collaboration

Peter L Freddolino 1 collaboration

Dominic Gilzer 1 collaboration

Chris Greening 1 collaboration

Rhys Grinter 1 collaboration

Manickam Gurusaran 1 collaboration

Marcus D Hartmann 1 collaboration

Charlie J Hitchman 1 collaboration

Ashleigh Kropp 1 collaboration

Petri Kursula 1 collaboration

Andrew L Lovering 1 collaboration

Bruno Lemaitre 1 collaboration

Andrea Lia 1 collaboration

Shiheng Liu 1 collaboration

Maria Logotheti 1 collaboration

Shuze Lu 1 collaboration

Sigurbjörn Markússon 1 collaboration

Mitchell D Miller 1 collaboration

George Minasov 1 collaboration

Hartmut H Niemann 1 collaboration

Felipe Opazo 1 collaboration

George N Phillips 1 collaboration

Owen R Davies 1 collaboration

Samuel Rommelaere 1 collaboration

Monica Rosas-Lemus 1 collaboration

Pietro Roversi 1 collaboration

Karla Satchell 1 collaboration

Nathan Smith 1 collaboration

Mark A Wilson 1 collaboration

Kuan-Lin Wu 1 collaboration

Xian Xia 1 collaboration

Han Xiao 1 collaboration

Wenhua Zhang 1 collaboration

Z Hong Zhou 1 collaboration

Krzysztof Fidelis 1 collaboration

Maya Topf 1 collaboration

John Moult 1 collaboration

Torsten Schwede 1 collaboration

Victor Margitich 1 collaboration

Aartjan J W Te Velthuis 1 collaboration

Hana Veler 1 collaboration

Marjorie Fournier 1 collaboration