H Döhner

Affiliations

Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.

Publications (68)

Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.

The Journal of experimental medicine

Avec: Faisal Basheer , George Giotopoulos , Eshwar Meduri , Haiyang Yun , Milena Mazan , Daniel Sasca , Paolo Gallipoli , Ludovica Marando , Malgorzata Gozdecka , Ryan Asby , Olivia Sheppard , Monika Dudek , Lars Bullinger , Hartmut Döhner , Richard Dillon , Sylvie Freeman , Oliver Ottmann , Alan Burnett , Nigel Russell , Elli Papaemmanuil , Robert Hills , Peter Campbell , George S Vassiliou , Brian J P Huntly

Gemtuzumab Ozogamicin in

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Richard F Schlenk , Peter Paschka , Julia Krzykalla , Daniela Weber , Silke Kapp-Schwoerer , Verena I Gaidzik , Claudia Leis , Walter Fiedler , Thomas Kindler , Thomas Schroeder , Karin Mayer , Michael Lübbert , Mohammed Wattad , Katharina Götze , Heinz A Horst , Elisabeth Koller , Gerald Wulf , Jan Schleicher , Martin Bentz , Richard Greil , Bernd Hertenstein , Jürgen Krauter , Uwe Martens , David Nachbaur , Maisun Abu Samra , Michael Girschikofsky , Nadezda Basara , Axel Benner , Felicitas Thol , Michael Heuser , Arnold Ganser , Konstanze Döhner , Hartmut Döhner

Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with

Haematologica

Avec: Ali Bazarbachi , Gesine Bug , Frederic Baron , Eolia Brissot , Fabio Ciceri , Iman Abou Dalle , Hartmut Döhner , Jordi Esteve , Yngvar Floisand , Sebastian Giebel , Maria Gilleece , Norbert-Claude Gorin , Elias Jabbour , Mahmoud Aljurf , Hagop Kantarjian , Mohamed Kharfan-Dabaja , Myriam Labopin , Francesco Lanza , Florent Malard , Zinaida Peric , Thomas Prebet , Farhad Ravandi , Annalisa Ruggeri , Jaime Sanz , Christoph Schmid , Roni Shouval , Alexandros Spyridonidis , Jurjen Versluis , Norbert Vey , Bipin N Savani , Arnon Nagler , Mohamad Mohty

Monosomal karyotype and chromosome 17p loss or TP53 mutations in decitabine-treated patients with acute myeloid leukemia.

Annals of hematology

Avec: Heiko Becker , Dietmar Pfeifer , Gabriele Ihorst , Milena Pantic , Julius Wehrle , Björn H Rüter , Lars Bullinger , Björn Hackanson , Ulrich Germing , Andrea Kuendgen , Uwe Platzbecker , Konstanze Döhner , Arnold Ganser , Anne Hagemeijer , Pierre W Wijermans , Hartmut Döhner , Justus Duyster , Michael Lübbert

Early treatment with FCR versus watch and wait in patients with stage Binet A high-risk chronic lymphocytic leukemia (CLL): a randomized phase 3 trial.

Leukemia

Avec: Carmen D Herling , Florence Cymbalista , Carolin Groß-Ophoff-Müller , Jasmin Bahlo , Sandra Robrecht , Petra Langerbeins , Anna-Maria Fink , Othman Al-Sawaf , Raymonde Busch , Raphael Porcher , Bruno Cazin , Brigitte Dreyfus , Stefan Ibach , Stéphane Leprêtre , Kirsten Fischer , Florian Kaiser , Barbara Eichhorst , Clemens-Martin Wentner , Manuela A Hoechstetter , Hartmut Döhner , Veronique Leblond , Michael Kneba , Remi Letestu , Sebastian Böttcher , Stephan Stilgenbauer , Michael Hallek , Vincent Levy

Valproate and Retinoic Acid in Combination With Decitabine in Elderly Nonfit Patients With Acute Myeloid Leukemia: Results of a Multicenter, Randomized, 2 × 2, Phase II Trial.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Michael Lübbert , Olga Grishina , Claudia Schmoor , Richard F Schlenk , Edgar Jost , Martina Crysandt , Michael Heuser , Felicitas Thol , Helmut R Salih , Marcus M Schittenhelm , Ulrich Germing , Andrea Kuendgen , Katharina S Götze , Hans-Walter Lindemann , Carsten Müller-Tidow , Gerhard Heil , Sebastian Scholl , Gesine Bug , Carsten Schwaenen , Aristoteles Giagounidis , Andreas Neubauer , Jürgen Krauter , Wolfram Brugger , Maike De Wit , Ralph Wäsch , Heiko Becker , Annette M May , Justus Duyster , Konstanze Döhner , Arnold Ganser , Björn Hackanson , Hartmut Döhner , Auteur inconnu

Respiratory syncytial virus and human metapneumovirus after allogeneic hematopoietic stem cell transplantation: Impact of the immunodeficiency scoring index, viral load, and ribavirin treatment on the outcomes.

Transplant infectious disease : an official journal of the Transplantation Society

Avec: Mobil Akhmedov , Verena Wais , Elisa Sala , Adela Neagoie , Thanh Mai Nguyen , Andrea Gantner , Stephanie von Harsdorf , Florian Kuchenbauer , Axel Schubert , Detlef Michel , Hartmut Döhner , Donald Bunjes

Real-world experience of CPX-351 as first-line treatment for patients with acute myeloid leukemia.

Blood cancer journal

Avec: Christina Rautenberg , Friedrich Stölzel , Christoph Röllig , Matthias Stelljes , Verena Gaidzik , Michael Lauseker , Oliver Kriege , Mareike Verbeek , Julia Marie Unglaub , Felicitas Thol , Stefan W Krause , Mathias Hänel , Charlotte Neuerburg , Vladan Vucinic , Christian-Friedrich Jehn , Julia Severmann , Maxi Wass , Lars Fransecky , Jens Chemnitz , Udo Holtick , Kerstin Schäfer-Eckart , Josephine Schröder , Sabrina Kraus , William Krüger , Ulrich Kaiser , Sebastian Scholl , Kathrin Koch , Lea Henning , Guido Kobbe , Rainer Haas , Nael Alakel , Maximilian-Alexander Röhnert , Katja Sockel , Maher Hanoun , Uwe Platzbecker , Tobias A W Holderried , Anke Morgner , Michael Heuser , Tim Sauer , Katharina S Götze , Eva Wagner-Drouet , Konstanze Döhner , Hartmut Döhner , Christoph Schliemann , Johannes Schetelig , Martin Bornhäuser , Ulrich Germing , Thomas Schroeder , Jan Moritz Middeke

Clonal evolution in chronic lymphocytic leukemia is scant in relapsed but accelerated in refractory cases after chemo(immune) therapy.

Haematologica

Avec: Marc Zapatka , Eugen Tausch , Selcen Öztürk , Deyan Yordanov Yosifov , Martina Seiffert , Thorsten Zenz , Christof Schneider , Johannes Blöhdorn , Hartmut Döhner , Daniel Mertens , Peter Lichter , Stephan Stilgenbauer

Couples Coping With Hematological Cancer: Support Within and Outside the Couple - Findings From a Qualitative Analysis of Dyadic Interviews.

Frontiers in psychology

Avec: Daniela Bodschwinna , Gregor Weissflog , Hartmut Döhner , Dietger Niederwieser , Anja Mehnert-Theuerkauf , Harald Gündel , Jochen Ernst , Ute Goerling , Klaus Hönig

Guadecitabine vs TC in relapsed/refractory AML after intensive chemotherapy: randomized phase 3 ASTRAL-2 trial.

Blood advances

Avec: Gail J Roboz , Guillermo F Sanz , Elizabeth A Griffiths , Karen W L Yee , Hagop M Kantarjian , Christian Récher , Michael T Byrne , Elzbieta Patkowska , Hee Je Kim , Xavier Thomas , Ine Moors , Wendy Stock , Arpad Illes , Pierre Fenaux , Yasushi Miyazaki , Takahiro Yamauchi , Casey O'Connell , Yong Hao , Harold Neal Keer , Mohammad Azab , Hartmut Döhner

Long-term follow-up of VIALE-A: Venetoclax and azacitidine in chemotherapy-ineligible untreated acute myeloid leukemia.

American journal of hematology

Avec: Keith W Pratz , Brian A Jonas , Vinod Pullarkat , Michael J Thirman , Jacqueline S Garcia , Hartmut Döhner , Christian Récher , Walter Fiedler , Kazuhito Yamamoto , Jianxiang Wang , Sung-Soo Yoon , Ofir Wolach , Su-Peng Yeh , Brian Leber , Jordi Esteve , Jiri Mayer , Kimmo Porkka , Árpád Illés , Roberto M Lemoli , Mehmet Turgut , Grace Ku , Catherine Miller , Ying Zhou , Meng Zhang , Brenda Chyla , Jalaja Potluri , Courtney D DiNardo

International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data.

Blood

Avec: Daniel A Arber , Attilio Orazi , Robert P Hasserjian , Michael J Borowitz , Katherine R Calvo , Hans-Michael Kvasnicka , Sa A Wang , Adam Bagg , Tiziano Barbui , Susan Branford , Carlos E Bueso-Ramos , Jorge E Cortes , Paola Dal Cin , Courtney D DiNardo , Hervé Dombret , Eric J Duncavage , Benjamin L Ebert , Elihu H Estey , Fabio Facchetti , Kathryn Foucar , Naseema Gangat , Umberto Gianelli , Lucy A Godley , Nicola Gökbuget , Jason Gotlib , Eva Hellström-Lindberg , Gabriela S Hobbs , Ronald Hoffman , Elias J Jabbour , Jean-Jacques Kiladjian , Richard A Larson , Michelle M Le Beau , Mignon L-C Loh , Bob Löwenberg , Elizabeth Macintyre , Luca Malcovati , Charles G Mullighan , Charlotte Niemeyer , Olatoyosi M Odenike , Seishi Ogawa , Alberto Orfao , Elli Papaemmanuil , Francesco Passamonti , Kimmo Porkka , Ching-Hon Pui , Jerald P Radich , Andreas Reiter , Maria Rozman , Martina Rudelius , Michael R Savona , Charles A Schiffer , Annette Schmitt-Graeff , Akiko Shimamura , Jorge Sierra , Wendy A Stock , Richard M Stone , Martin S Tallman , Jürgen Thiele , Hwei-Fang Tien , Alexandar Tzankov , Alessandro M Vannucchi , Paresh Vyas , Andrew H Wei , Olga K Weinberg , Agnieszka Wierzbowska , Mario Cazzola , Hartmut Döhner , Ayalew Tefferi

Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial.

Leukemia

Avec: Nikolaus Jahn , Ekaterina Jahn , Maral Saadati , Lars Bullinger , Richard A Larson , Tiziana Ottone , Sergio Amadori , Thomas W Prior , Joseph M Brandwein , Frederick R Appelbaum , Bruno C Medeiros , Martin S Tallman , Gerhard Ehninger , Michael Heuser , Arnold Ganser , Celine Pallaud , Insa Gathmann , Julia Krzykalla , Axel Benner , Clara D Bloomfield , Christian Thiede , Richard M Stone , Hartmut Döhner , Konstanze Döhner

Intensive chemotherapy with or without gemtuzumab ozogamicin in patients with NPM1-mutated acute myeloid leukaemia (AMLSG 09-09): a randomised, open-label, multicentre, phase 3 trial.

The Lancet. Haematology

Avec: Hartmut Döhner , Daniela Weber , Julia Krzykalla , Walter Fiedler , Michael W M Kühn , Thomas Schroeder , Karin Mayer , Michael Lübbert , Mohammed Wattad , Katharina Götze , Lars Fransecky , Elisabeth Koller , Gerald Wulf , Jan Schleicher , Mark Ringhoffer , Richard Greil , Bernd Hertenstein , Jürgen Krauter , Uwe M Martens , David Nachbaur , Maisun Abu Samra , Sigrid Machherndl-Spandl , Nadezda Basara , Claudia Leis , Anika Schrade , Silke Kapp-Schwoerer , Sibylle Cocciardi , Lars Bullinger , Felicitas Thol , Michael Heuser , Peter Paschka , Verena I Gaidzik , Maral Saadati , Axel Benner , Richard F Schlenk , Konstanze Döhner , Arnold Ganser , Auteur inconnu

Risk factors and characteristics influencing humoral response to COVID-19 vaccination in patients after allogeneic stem cell transplantation.

Frontiers in immunology

Avec: Marie Luise Hütter-Krönke , Adela Neagoie , Igor Wolfgang Blau , Verena Wais , Lam Vuong , Andrea Gantner , Johann Ahn , Olaf Penack , Jacqueline Schnell , Klaus Axel Nogai , Bettina Eberspächer , Maral Saadati , Axel Benner , Lars Bullinger , Hartmut Döhner , Donald Bunjes , Elisa Sala

Desmoplastic Small Round Cell Tumors: Clinical Presentation, Molecular Characterization, and Therapeutic Approach of Seven Patients.

Sarcoma

Avec: Verena I Gaidzik , Regine Mayer-Steinacker , Mathias Wittau , Markus Schultheiß , Alexandra V Baer , Kathrin Oehl-Huber , Sonja Dahlum , Anja Fischer , Uwe Gerstenmaier , Thomas Seufferlein , Andreas Buck , Ambros Beer , Wolfgang Thaiss , Peter Möller , Hartmut Döhner , Reiner Siebert , Ralf Marienfeld , Thomas F E Barth

Prognostic and predictive impact of genetic markers in patients with CLL treated with obinutuzumab and venetoclax.

Blood

Avec: Eugen Tausch , Christof Schneider , Sandra Robrecht , Can Zhang , Anna Dolnik , Johannes Bloehdorn , Jasmin Bahlo , Othman Al-Sawaf , Matthias Ritgen , Anna-Maria Fink , Barbara Eichhorst , Karl-Anton Kreuzer , Maneesh Tandon , Kathryn Humphrey , Yanwen Jiang , William Schary , Lars Bullinger , Daniel Mertens , Michele Porro Lurà , Michael Kneba , Hartmut Döhner , Kirsten Fischer , Michael Hallek , Stephan Stilgenbauer

TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition.

Leukemia

Avec: Shiva Bamezai , Deniz Demir , Alex Jose Pulikkottil , Fabio Ciccarone , Elena Fischbein , Amit Sinha , Chiara Borga , Geertruy Te Kronnie , Lüder-Hinrich Meyer , Fabian Mohr , Maria Götze , Paola Caiafa , Klaus-Michael Debatin , Konstanze Döhner , Hartmut Döhner , Irene González-Menéndez , Leticia Quintanilla-Fend , Tobias Herold , Irmela Jeremias , Michaela Feuring-Buske , Christian Buske , Vijay P S Rawat

Prognostic model for newly diagnosed CLL patients in Binet stage A: results of the multicenter, prospective CLL1 trial of the German CLL study group.

Leukemia

Avec: Manuela A Hoechstetter , Raymonde Busch , Barbara Eichhorst , Andreas Bühler , Dirk Winkler , Jasmin Bahlo , Sandra Robrecht , Michael J Eckart , Ursula Vehling-Kaiser , Georg Jacobs , Ulrich Jäger , Hans Jürgen Hurtz , Georg Hopfinger , Frank Hartmann , Harald Fuss , Wolfgang Abenhardt , Ilona Blau , Werner Freier , Lothar Müller , Maria Goebeler , Clemens Wendtner , Kirsten Fischer , Carmen D Herling , Michael Starck , Martin Bentz , Bertold Emmerich , Hartmut Döhner , Stephan Stilgenbauer , Michael Hallek

Oxidative stress as candidate therapeutic target to overcome microenvironmental protection of CLL.

Leukemia

Avec: Deyan Yordanov Yosifov , Irina Idler , Nupur Bhattacharya , Michaela Reichenzeller , Viola Close , Daria Ezerina , Annika Scheffold , Billy Michael Chelliah Jebaraj , Sabrina Kugler , Johannes Bloehdorn , Jasmin Bahlo , Sandra Robrecht , Barbara Eichhorst , Kirsten Fischer , Anja Weigel , Hauke Busch , Peter Lichter , Hartmut Döhner , Tobias P Dick , Stephan Stilgenbauer , Daniel Mertens

Management of acute promyelocytic leukemia: updated recommendations from an expert panel of the European LeukemiaNet.

Blood

Avec: Miguel A Sanz , Pierre Fenaux , Martin S Tallman , Elihu H Estey , Bob Löwenberg , Tomoki Naoe , Eva Lengfelder , Hartmut Döhner , Alan K Burnett , Sai-Juan Chen , Vikram Mathews , Harry Iland , Eduardo Rego , Hagop Kantarjian , Lionel Adès , Giuseppe Avvisati , Pau Montesinos , Uwe Platzbecker , Farhad Ravandi , Nigel H Russell , Francesco Lo-Coco

Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation.

Nature communications

Avec: Sibylle Cocciardi , Anna Dolnik , Silke Kapp-Schwoerer , Frank G Rücker , Susanne Lux , Tamara J Blätte , Sabrina Skambraks , Jan Krönke , Florian H Heidel , Tina M Schnöder , Andrea Corbacioglu , Verena I Gaidzik , Peter Paschka , Veronica Teleanu , Gudrun Göhring , Felicitas Thol , Michael Heuser , Arnold Ganser , Daniela Weber , Eric Sträng , Hans A Kestler , Hartmut Döhner , Lars Bullinger , Konstanze Döhner

INPART - a psycho-oncological intervention for partners of patients with haemato-oncological disease - study protocol.

BMC cancer

Avec: Inga Lorenz , Daniela Bodschwinna , Nina Hallensleben , Hartmut Döhner , Dietger Niederwieser , Tanja Zimmermann , Anja Mehnert , Harald Gündel , Jochen Ernst , Klaus Hoenig

KIT D816 mutated/CBF-negative acute myeloid leukemia: a poor-risk subtype associated with systemic mastocytosis.

Leukemia

Avec: Mohamad Jawhar , Konstanze Döhner , Sebastian Kreil , Juliana Schwaab , Khalid Shoumariyeh , Manja Meggendorfer , Lambert L F Span , Stephan Fuhrmann , Nicole Naumann , Hans-Peter Horny , Karl Sotlar , Boris Kubuschok , Nikolas von Bubnoff , Karsten Spiekermann , Michael Heuser , Georgia Metzgeroth , Alice Fabarius , Stefan Klein , Wolf-Karsten Hofmann , Hanneke C Kluin-Nelemans , Torsten Haferlach , Hartmut Döhner , Nicholas C P Cross , Wolfgang R Sperr , Peter Valent , Andreas Reiter

Enasidenib plus azacitidine versus azacitidine alone in patients with newly diagnosed, mutant-IDH2 acute myeloid leukaemia (AG221-AML-005): a single-arm, phase 1b and randomised, phase 2 trial.

The Lancet. Oncology

Avec: Courtney D DiNardo , Andre C Schuh , Eytan M Stein , Pau Montesinos , Andrew H Wei , Stéphane de Botton , Amer M Zeidan , Amir T Fathi , Hagop M Kantarjian , John M Bennett , Mark G Frattini , Patricia Martin-Regueira , Frederik Lersch , Jing Gong , Maroof Hasan , Paresh Vyas , Hartmut Döhner

Deregulated expression of circular RNAs in acute myeloid leukemia.

Blood advances

Avec: Susanne Lux , Tamara J Blätte , Bernhard Gillissen , Antje Richter , Sibylle Cocciardi , Sabrina Skambraks , Klaus Schwarz , Hubert Schrezenmeier , Hartmut Döhner , Konstanze Döhner , Anna Dolnik , Lars Bullinger

Prognostic impact of prevalent chronic lymphocytic leukemia stereotyped subsets: analysis within prospective clinical trials of the German CLL Study Group (GCLLSG).

Haematologica

Avec: Sonia Jaramillo , Andreas Agathangelidis , Christof Schneider , Jasmin Bahlo , Sandra Robrecht , Eugen Tausch , Johannes Bloehdorn , Manuela Hoechstetter , Kirsten Fischer , Barbara Eichhorst , Valentin Goede , Michael Hallek , Hartmut Döhner , Richard Rosenquist , Paolo Ghia , Kostas Stamatopoulos , Stephan Stilgenbauer

Genomic heterogeneity in core-binding factor acute myeloid leukemia and its clinical implication.

Blood advances

Avec: Nikolaus Jahn , Tobias Terzer , Eric Sträng , Anna Dolnik , Sibylle Cocciardi , Ekaterina Panina , Andrea Corbacioglu , Julia Herzig , Daniela Weber , Anika Schrade , Katharina Götze , Thomas Schröder , Michael Lübbert , Dominique Wellnitz , Elisabeth Koller , Richard F Schlenk , Verena I Gaidzik , Peter Paschka , Frank G Rücker , Michael Heuser , Felicitas Thol , Arnold Ganser , Axel Benner , Hartmut Döhner , Lars Bullinger , Konstanze Döhner

Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial.

Blood

Avec: Silke Kapp-Schwoerer , Daniela Weber , Andrea Corbacioglu , Verena I Gaidzik , Peter Paschka , Jan Krönke , Frauke Theis , Frank G Rücker , Maria-Veronica Teleanu , Ekaterina Panina , Nikolaus Jahn , Julia Herzig , Lena Kubanek , Anika Schrade , Gudrun Göhring , Walter Fiedler , Thomas Kindler , Thomas Schroeder , Karin T Mayer , Michael Lübbert , Mohammed Wattad , Katharina S Götze , Heinz A Horst , Elisabeth Koller , Gerald Wulf , Jan Schleicher , Martin Bentz , Jürgen Krauter , Lars Bullinger , Julia Krzykalla , Axel Benner , Richard F Schlenk , Felicitas Thol , Michael Heuser , Arnold Ganser , Hartmut Döhner , Konstanze Döhner

Comprehensive CRISPR-Cas9 screens identify genetic determinants of drug responsiveness in multiple myeloma.

Blood advances

Avec: Stephan R Bohl , Laura K Schmalbrock , Imke Bauhuf , Tatjana Meyer , Anna Dolnik , Martin Szyska , Tamara J Blätte , Sarah Knödler , Linda Röhner , Denise Miller , Miriam Kull , Christian Langer , Hartmut Döhner , Anthony Letai , Frederik Damm , Dirk Heckl , Lars Bullinger , Jan Krönke

Modeling the B-cell receptor signaling on single cell level reveals a stable network circuit topology between nonmalignant B cells and chronic lymphocytic leukemia cells and between untreated cells and cells treated with kinase inhibitors.

International journal of cancer

Avec: Christine Wolf , Carsten Maus , Michael R O Persicke , Katharina Filarsky , Eugen Tausch , Christof Schneider , Hartmut Döhner , Stephan Stilgenbauer , Peter Lichter , Thomas Höfer , Daniel Mertens

Distinguishing AML from MDS: a fixed blast percentage may no longer be optimal.

Blood

Avec: Elihu Estey , Robert P Hasserjian , Hartmut Döhner

Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.

Nature communications

Avec: Yuen Lam Dora Ng , Evelyn Ramberger , Stephan R Bohl , Anna Dolnik , Christian Steinebach , Theresia Conrad , Sina Müller , Oliver Popp , Miriam Kull , Mohamed Haji , Michael Gütschow , Hartmut Döhner , Wolfgang Walther , Ulrich Keller , Lars Bullinger , Philipp Mertins , Jan Krönke

Cancer care in German centers of excellence during the first 2 years of the COVID-19 pandemic.

Journal of cancer research and clinical oncology

Avec: Volker Arndt , Daniela Doege , Stefan Fröhling , Peter Albers , Hana Algül , Ralf Bargou , Carsten Bokemeyer , Martin Bornhäuser , Christian H Brandts , Peter Brossart , Sara Yvonne Brucker , Tim H Brümmendorf , Hartmut Döhner , Norbert Gattermann , Michael Hallek , Volker Heinemann , Ulrich Keilholz , Thomas Kindler , Cornelia von Levetzow , Florian Lordick , Ulf Peter Neumann , Christoph Peters , Dirk Schadendorf , Stephan Stilgenbauer , Thomas Zander , Daniel Zips , Delia Braun , Thomas Seufferlein , Gerd Nettekoven , Michael Baumann

How I treat refractory and relapsed acute myeloid leukemia.

Blood

Avec: Felicitas R Thol , Hartmut Döhner , Arnold Ganser

Survival outcomes in patients with acute myeloid leukaemia who received subsequent therapy for relapse in QUAZAR AML-001.

British journal of haematology

Avec: Farhad Ravandi , Hartmut Döhner , Andrew H Wei , Pau Montesinos , Michael Pfeilstöcker , Cristina Papayannidis , Yinzhi Lai , Kefeng Wang , Wendy L See , Daniel Lopes de Menezes , Erica Petrlik , Thomas Prebet , Gail J Roboz

Neurological complications of the central nervous system after allogeneic stem cell transplantation: the role of TA-TMA as a potential underreported cause.

Transplantation and cellular therapy

Avec: Elisa Sala , Adela M Neagoie , Jan Lewerenz , Maral Saadati , Axel Benner , Andrea Gantner , Verena Wais , Hartmut Döhner , Donald Bunjes

Rituximab and obinutuzumab differentially hijack the B cell receptor and NOTCH1 signaling pathways.

iScience

Avec: Jennifer Edelmann , Arran D Dokal , Emma Vilventhraraja , Karlheinz Holzmann , David Britton , Tetyana Klymenko , Hartmut Döhner , Mark Cragg , Andrejs Braun , Pedro Cutillas , John G Gribben

Integrative prognostic models predict long-term survival after immunochemotherapy in chronic lymphocytic leukemia patients.

Haematologica

Avec: Johannes Bloehdorn , Julia Krzykalla , Karlheinz Holzmann , Andreas Gerhardinger , Billy Michael Chelliah Jebaraj , Jasmin Bahlo , Kathryn Humphrey , Eugen Tausch , Sandra Robrecht , Daniel Mertens , Christof Schneider , Kirsten Fischer , Michael Hallek , Hartmut Döhner , Axel Benner , Stephan Stilgenbauer

Randomized phase-II trial evaluating induction therapy with idarubicin and etoposide plus sequential or concurrent azacitidine and maintenance therapy with azacitidine.

Leukemia

Avec: R F Schlenk , D Weber , W Herr , G Wulf , H R Salih , H G Derigs , A Kuendgen , M Ringhoffer , B Hertenstein , U M Martens , M Grießhammer , H Bernhard , J Krauter , M Girschikofsky , D Wolf , E Lange , J Westermann , E Koller , S Kremers , M Wattad , M Heuser , F Thol , G Göhring , D Haase , V Teleanu , V Gaidzik , A Benner , K Döhner , A Ganser , P Paschka ,

Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were increased by immune checkpoint inhibition.

Cancer immunology, immunotherapy : CII

Avec: Jochen Greiner , Marlies Götz , Susanne Hofmann , Hubert Schrezenmeier , Markus Wiesneth , Lars Bullinger , Hartmut Döhner , Vanessa Schneider

International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia.

Blood

Avec: Adalgisa Condoluci , Lodovico Terzi di Bergamo , Petra Langerbeins , Manuela A Hoechstetter , Carmen D Herling , Lorenzo De Paoli , Julio Delgado , Kari G Rabe , Massimo Gentile , Michael Doubek , Francesca R Mauro , Giorgia Chiodin , Mattias Mattsson , Jasmin Bahlo , Giovanna Cutrona , Jana Kotaskova , Clara Deambrogi , Karin E Smedby , Valeria Spina , Alessio Bruscaggin , Wei Wu , Riccardo Moia , Elena Bianchi , Bernhard Gerber , Emanuele Zucca , Silke Gillessen , Michele Ghielmini , Franco Cavalli , Georg Stussi , Mark A Hess , Tycho S Baumann , Antonino Neri , Manlio Ferrarini , Richard Rosenquist , Francesco Forconi , Robin Foà , Sarka Pospisilova , Fortunato Morabito , Stephan Stilgenbauer , Hartmut Döhner , Sameer A Parikh , William G Wierda , Emili Montserrat , Gianluca Gaidano , Michael Hallek , Davide Rossi

Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.

Nature communications

Avec: Johannes Bloehdorn , Andrejs Braun , Amaro Taylor-Weiner , Billy Michael Chelliah Jebaraj , Sandra Robrecht , Julia Krzykalla , Heng Pan , Adam Giza , Gulnara Akylzhanova , Karlheinz Holzmann , Annika Scheffold , Harvey E Johnston , Ru-Fang Yeh , Tetyana Klymenko , Eugen Tausch , Barbara Eichhorst , Lars Bullinger , Kirsten Fischer , Martin Weisser , Tadeusz Robak , Christof Schneider , John Gribben , Lekh N Dahal , Mathew J Carter , Olivier Elemento , Dan A Landau , Donna S Neuberg , Mark S Cragg , Axel Benner , Michael Hallek , Catherine J Wu , Hartmut Döhner , Stephan Stilgenbauer , Daniel Mertens

Adjunctive Volasertib in Patients With Acute Myeloid Leukemia not Eligible for Standard Induction Therapy: A Randomized, Phase 3 Trial.

HemaSphere

Avec: Hartmut Döhner , Argiris Symeonidis , Dries Deeren , Judit Demeter , Miguel A Sanz , Achilles Anagnostopoulos , Jordi Esteve , Walter Fiedler , Kimmo Porkka , Hee-Je Kim , Je-Hwan Lee , Kensuke Usuki , Stefano D'Ardia , Chul Won Jung , Olga Salamero , Heinz-August Horst , Christian Recher , Philippe Rousselot , Irwindeep Sandhu , Koen Theunissen , Felicitas Thol , Konstanze Döhner , Veronica Teleanu , Daniel J DeAngelo , Tomoki Naoe , Mikkael A Sekeres , Valerie Belsack , Miaomiao Ge , Tillmann Taube , Oliver G Ottmann

Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results.

Leukemia

Avec: Frank G Rücker , Ling Du , Tamara J Luck , Axel Benner , Julia Krzykalla , Insa Gathmann , Maria Teresa Voso , Sergio Amadori , Thomas W Prior , Joseph M Brandwein , Frederick R Appelbaum , Bruno C Medeiros , Martin S Tallman , Lynn Savoie , Jorge Sierra , Celine Pallaud , Miguel A Sanz , Joop H Jansen , Dietger Niederwieser , Thomas Fischer , Gerhard Ehninger , Michael Heuser , Arnold Ganser , Lars Bullinger , Richard A Larson , Clara D Bloomfield , Richard M Stone , Hartmut Döhner , Christian Thiede , Konstanze Döhner

A 2:1 randomized, open-label, phase II study of selinexor vs. physician's choice in older patients with relapsed or refractory acute myeloid leukemia.

Leukemia & lymphoma

Avec: Kendra Sweet , Bhavana Bhatnagar , Hartmut Döhner , Will Donnellan , Olga Frankfurt , Michael Heuser , Vamsi Kota , Hongtao Liu , Emmanuel Raffoux , Gail J Roboz , Christoph Röllig , Margaret M Showel , Stephen A Strickland , Susana Vives , Shijie Tang , Thaddeus J Unger , Anita Joshi , Yao Shen , Mariano J Alvarez , Andrea Califano , Marsha Crochiere , Yosef Landesman , Michael Kauffman , Jatin Shah , Sharon Shacham , Michael R Savona , Pau Montesinos

Oral azacitidine prolongs survival of patients with AML in remission independently of measurable residual disease status.

Blood

Avec: Gail J Roboz , Farhad Ravandi , Andrew H Wei , Hervé Dombret , Felicitas Thol , Maria Teresa Voso , Andre C Schuh , Kimmo Porkka , Ignazia La Torre , Barry Skikne , Jianhua Zhong , C L Beach , Alberto Risueño , Daniel L Menezes , Gert Ossenkoppele , Hartmut Döhner

Measurable Residual Disease Response and Prognosis in Treatment-Naïve Acute Myeloid Leukemia With Venetoclax and Azacitidine.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Keith W Pratz , Brian A Jonas , Vinod Pullarkat , Christian Recher , Andre C Schuh , Michael J Thirman , Jacqueline S Garcia , Courtney D DiNardo , Vladimir Vorobyev , Nicola S Fracchiolla , Su-Peng Yeh , Jun Ho Jang , Muhit Ozcan , Kazuhito Yamamoto , Arpad Illes , Ying Zhou , Monique Dail , Brenda Chyla , Jalaja Potluri , Hartmut Döhner

Obinutuzumab (GA-101), ibrutinib, and venetoclax (GIVe) frontline treatment for high-risk chronic lymphocytic leukemia.

Blood

Avec: Henriette Huber , Simone Edenhofer , Julia von Tresckow , Sandra Robrecht , Can Zhang , Eugen Tausch , Christof Schneider , Johannes Bloehdorn , Moritz Fürstenau , Peter Dreger , Matthias Ritgen , Thomas Illmer , Anna L Illert , Jan Dürig , Sebastian Böttcher , Carsten U Niemann , Michael Kneba , Anna-Maria Fink , Kirsten Fischer , Hartmut Döhner , Michael Hallek , Barbara Eichhorst , Stephan Stilgenbauer

Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients.

Journal of hematology & oncology

Avec: Adriane Halik , Marlon Tilgner , Patricia Silva , Natalia Estrada , Robert Altwasser , Ekaterina Jahn , Michael Heuser , Hsin-An Hou , Marta Pratcorona , Robert K Hills , Klaus H Metzeler , Laurene Fenwarth , Anna Dolnik , Christine Terre , Klara Kopp , Olga Blau , Martin Szyska , Friederike Christen , Jan Krönke , Loïc Vasseur , Bob Löwenberg , Jordi Esteve , Peter J M Valk , Matthieu Duchmann , Wen-Chien Chou , David C Linch , Hartmut Döhner , Rosemary E Gale , Konstanze Döhner , Lars Bullinger , Kenichi Yoshida , Frederik Damm

Rearrangements involving 11q23.3/KMT2A in adult AML: mutational landscape and prognostic implications - a HARMONY study.

Leukemia

Avec: Alberto Hernández-Sánchez , Teresa González , Marta Sobas , Eric Sträng , Gastone Castellani , María Abáigar , Peter J M Valk , Ángela Villaverde Ramiro , Axel Benner , Klaus H Metzeler , Raúl Azibeiro , Jesse M Tettero , Joaquín Martínez-López , Marta Pratcorona , Javier Martínez Elicegui , Ken I Mills , Christian Thiede , Guillermo Sanz , Konstanze Döhner , Michael Heuser , Torsten Haferlach , Amin T Turki , Dirk Reinhardt , Renate Schulze-Rath , Martje Barbus , Jesús María Hernández-Rivas , Brian Huntly , Gert Ossenkoppele , Hartmut Döhner , Lars Bullinger

Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia.

Blood

Avec: Eric J Duncavage , Adam Bagg , Robert P Hasserjian , Courtney D DiNardo , Lucy A Godley , Ilaria Iacobucci , Siddhartha Jaiswal , Luca Malcovati , Alessandro M Vannucchi , Keyur P Patel , Daniel A Arber , Maria E Arcila , Rafael Bejar , Nancy Berliner , Michael J Borowitz , Susan Branford , Anna L Brown , Catherine A Cargo , Hartmut Döhner , Brunangelo Falini , Guillermo Garcia-Manero , Torsten Haferlach , Eva Hellström-Lindberg , Annette S Kim , Jeffery M Klco , Rami Komrokji , Mignon Lee-Cheun Loh , Sanam Loghavi , Charles G Mullighan , Seishi Ogawa , Attilio Orazi , Elli Papaemmanuil , Andreas Reiter , David M Ross , Michael Savona , Akiko Shimamura , Radek C Skoda , Francesc Solé , Richard M Stone , Ayalew Tefferi , Matthew J Walter , David Wu , Benjamin L Ebert , Mario Cazzola

Prognostic impact of NPM1 and FLT3 mutations in patients with AML in first remission treated with oral azacitidine.

Blood

Avec: Hartmut Döhner , Andrew H Wei , Gail J Roboz , Pau Montesinos , Felicitas R Thol , Farhad Ravandi , Hervé Dombret , Kimmo Porkka , Irwindeep Sandhu , Barry Skikne , Wendy L See , Manuel Ugidos , Alberto Risueño , Esther T Chan , Anjan Thakurta , C L Beach , Daniel Lopes de Menezes

In vivo kinetics of early, non-random methylome and transcriptome changes induced by DNA-hypomethylating treatment in primary AML blasts.

Leukemia

Avec: Gabriele Greve , Geoffroy Andrieux , Pascal Schlosser , Nadja Blagitko-Dorfs , Usama-Ur Rehman , Tobias Ma , Dietmar Pfeifer , Gerhard Heil , Andreas Neubauer , Jürgen Krauter , Michael Heuser , Helmut R Salih , Konstanze Döhner , Hartmut Döhner , Björn Hackanson , Melanie Boerries , Michael Lübbert

Optimization of Radiolabeling of a [

Cancers

Avec: Gordon Winter , Carmen Hamp-Goldstein , Gabriel Fischer , Peter Kletting , Gerhard Glatting , Christoph Solbach , Hendrik Herrmann , Elisa Sala , Michaela Feuring , Hartmut Döhner , Ambros J Beer , Donald Bunjes , Vikas Prasad

Safety and efficacy of talacotuzumab plus decitabine or decitabine alone in patients with acute myeloid leukemia not eligible for chemotherapy: results from a multicenter, randomized, phase 2/3 study.

Leukemia

Avec: Pau Montesinos , Gail J Roboz , Claude-Eric Bulabois , Marion Subklewe , Uwe Platzbecker , Yishai Ofran , Cristina Papayannidis , Agnieszka Wierzbowska , Ho Jin Shin , Vadim Doronin , Stefan Deneberg , Su-Peng Yeh , Mehmet Ali Ozcan , Steven Knapper , Jorge Cortes , Daniel A Pollyea , Gert Ossenkoppele , Sergio Giralt , Hartmut Döhner , Michael Heuser , Liang Xiu , Indrajeet Singh , Fei Huang , Julie S Larsen , Andrew H Wei

DNA methylation of chronic lymphocytic leukemia with differential response to chemotherapy.

Scientific data

Avec: Deyan Yordanov Yosifov , Johannes Bloehdorn , Hartmut Döhner , Peter Lichter , Stephan Stilgenbauer , Daniel Mertens

Measurable residual disease monitoring in acute myeloid leukemia with t(8;21)(q22;q22.1): results from the AML Study Group.

Blood

Avec: Frank G Rücker , Mridul Agrawal , Andrea Corbacioglu , Daniela Weber , Silke Kapp-Schwoerer , Verena I Gaidzik , Nikolaus Jahn , Thomas Schroeder , Mohammed Wattad , Michael Lübbert , Elisabeth Koller , Thomas Kindler , Katharina Götze , Mark Ringhoffer , Jörg Westermann , Walter Fiedler , Heinz A Horst , Richard Greil , Roland Schroers , Karin Mayer , Thomas Heinicke , Jürgen Krauter , Richard F Schlenk , Felicitas Thol , Michael Heuser , Arnold Ganser , Lars Bullinger , Peter Paschka , Hartmut Döhner , Konstanze Döhner

Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription.

Haematologica

Avec: Jennifer Edelmann , Karlheinz Holzmann , Eugen Tausch , Emily A Saunderson , Billy M C Jebaraj , Daniela Steinbrecher , Anna Dolnik , Tamara J Blätte , Dan A Landau , Jenny Saub , Sven Estenfelder , Stefan Ibach , Florence Cymbalista , Veronique Leblond , Alain Delmer , Jasmin Bahlo , Sandra Robrecht , Kirsten Fischer , Valentin Goede , Lars Bullinger , Catherine J Wu , Daniel Mertens , Gabriella Ficz , John G Gribben , Michael Hallek , Hartmut Döhner , Stephan Stilgenbauer

Short telomeres are associated with inferior outcome, genomic complexity, and clonal evolution in chronic lymphocytic leukemia.

Leukemia

Avec: Billy Michael Chelliah Jebaraj , Eugen Tausch , Dan A Landau , Jasmin Bahlo , Sandra Robrecht , Amaro N Taylor-Weiner , Johannes Bloehdorn , Annika Scheffold , Daniel Mertens , Sebastian Böttcher , Michael Kneba , Ulrich Jäger , Thorsten Zenz , Michael K Wenger , Guenter Fingerle-Rowson , Clemens Wendtner , Anna-Maria Fink , Catherine J Wu , Barbara Eichhorst , Kirsten Fischer , Michael Hallek , Hartmut Döhner , Stephan Stilgenbauer

Oral Azacitidine (CC-486) for the Treatment of Myeloid Malignancies.

Clinical lymphoma, myeloma & leukemia

Avec: Guillermo Garcia-Manero , Hartmut Döhner , Andrew H Wei , Ignazia La Torre , Barry Skikne , C L Beach , Valeria Santini

Survivin' Acute Myeloid Leukaemia-A Personalised Target for inv(16) Patients.

International journal of molecular sciences

Avec: Jochen Greiner , Elliott Brown , Lars Bullinger , Robert K Hills , Vanessa Morris , Hartmut Döhner , Ken I Mills , Barbara-Ann Guinn

Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study.

Blood

Avec: Eytan M Stein , Courtney D DiNardo , Amir T Fathi , Alice S Mims , Keith W Pratz , Michael R Savona , Anthony S Stein , Richard M Stone , Eric S Winer , Christopher S Seet , Hartmut Döhner , Daniel A Pollyea , James K McCloskey , Olatoyosi Odenike , Bob Löwenberg , Gert J Ossenkoppele , Prapti A Patel , Mikhail Roshal , Mark G Frattini , Frederik Lersch , Aleksandra Franovic , Salah Nabhan , Bin Fan , Sung Choe , Hongfang Wang , Bin Wu , Lei Hua , Caroline Almon , Michael Cooper , Hagop M Kantarjian , Martin S Tallman

Mutant Isocitrate Dehydrogenase 1 Inhibitor Ivosidenib in Combination With Azacitidine for Newly Diagnosed Acute Myeloid Leukemia.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Courtney D DiNardo , Anthony S Stein , Eytan M Stein , Amir T Fathi , Olga Frankfurt , Andre C Schuh , Hartmut Döhner , Giovanni Martinelli , Prapti A Patel , Emmanuel Raffoux , Peter Tan , Amer M Zeidan , Stéphane de Botton , Hagop M Kantarjian , Richard M Stone , Mark G Frattini , Frederik Lersch , Jing Gong , Diego A Gianolio , Vickie Zhang , Aleksandra Franovic , Bin Fan , Meredith Goldwasser , Scott Daigle , Sung Choe , Bin Wu , Thomas Winkler , Paresh Vyas

Midostaurin in patients with acute myeloid leukemia and FLT3-TKD mutations: a subanalysis from the RATIFY trial.

Blood advances

Avec: Maria Teresa Voso , Richard A Larson , Dan Jones , Guido Marcucci , Thomas Prior , Jürgen Krauter , Michael Heuser , Serena Lavorgna , Josep Nomdedeu , Susan M Geyer , Alison Walker , Andrew H Wei , Jorge Sierra , Miguel A Sanz , Joseph M Brandwein , Theo M de Witte , Joop H Jansen , Dietger Niederwieser , Frederick R Appelbaum , Bruno C Medeiros , Martin S Tallman , Richard F Schlenk , Arnold Ganser , Sergio Amadori , Yuan Cheng , YinMiao Chen , Celine Pallaud , Ling Du , Alfonso Piciocchi , Gerhard Ehninger , John Byrd , Christian Thiede , Konstanze Döhner , Richard M Stone , Hartmut Döhner , Clara D Bloomfield , Francesco Lo-Coco

Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin.

Blood

Avec: Laura K Schmalbrock , Anna Dolnik , Sibylle Cocciardi , Eric Sträng , Frauke Theis , Nikolaus Jahn , Ekaterina Panina , Tamara J Blätte , Julia Herzig , Sabrina Skambraks , Frank G Rücker , Verena I Gaidzik , Peter Paschka , Walter Fiedler , Helmut R Salih , Gerald Wulf , Thomas Schroeder , Michael Lübbert , Richard F Schlenk , Felicitas Thol , Michael Heuser , Richard A Larson , Arnold Ganser , Hendrik G Stunnenberg , Saverio Minucci , Richard M Stone , Clara D Bloomfield , Hartmut Döhner , Konstanze Döhner , Lars Bullinger

Genetic alterations in Thai adult patients with acute myeloid leukemia and myelodysplastic syndrome-excess blasts detected by next-generation sequencing technique.

Annals of hematology

Avec: Weerapat Owattanapanich , Julia Herzig , Nikolaus Jahn , Ekaterina Panina , Theera Ruchutrakool , Smith Kungwankiattichai , Surapol Issaragrisil , Hartmut Döhner , Konstanze Döhner

Réseau de co-auteurs

Hartmut Döhner 67 collaborations

Lars Bullinger 21 collaborations

Konstanze Döhner 21 collaborations

Michael Heuser 18 collaborations

Stephan Stilgenbauer 15 collaborations

Arnold Ganser 13 collaborations

Axel Benner 11 collaborations

Felicitas Thol 11 collaborations

Michael Hallek 11 collaborations

Sandra Robrecht 10 collaborations

Kirsten Fischer 10 collaborations

Michael Lübbert 9 collaborations

Jasmin Bahlo 9 collaborations

Eugen Tausch 9 collaborations

Daniel Mertens 9 collaborations

Anna Dolnik 9 collaborations

Richard F Schlenk 8 collaborations

Verena I Gaidzik 8 collaborations

Barbara Eichhorst 8 collaborations

Richard M Stone 8 collaborations

Andrew H Wei 8 collaborations

Johannes Bloehdorn 8 collaborations

Peter Paschka 7 collaborations

Julia Krzykalla 7 collaborations

Walter Fiedler 7 collaborations

Jürgen Krauter 7 collaborations

Christof Schneider 7 collaborations

Courtney D DiNardo 7 collaborations

Daniela Weber 6 collaborations

Thomas Schroeder 6 collaborations

Gail J Roboz 6 collaborations

Martin S Tallman 6 collaborations

Nikolaus Jahn 6 collaborations

Pau Montesinos 6 collaborations

Frank G Rücker 6 collaborations

Silke Kapp-Schwoerer 5 collaborations

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Kimmo Porkka 5 collaborations

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None None 2 collaborations

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Frank Hartmann 1 collaboration

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