Dirk Schadendorf

Affiliations

University Hospital Essen, Essen, Germany; German Cancer Consortium, Heidelberg, Germany. Electronic address: Dirk.Schadendorf@uk-essen.de.

Publications (100)

The concepts of rechallenge and retreatment in melanoma: A proposal for consensus definitions.

European journal of cancer (Oxford, England : 1990)

Avec: Christoffer Gebhardt , Paolo Ascierto , Victoria Atkinson , Pippa Corrie , Reinhard Dummer , Dirk Schadendorf

Author Correction: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma.

Nature medicine

Avec: David Liu , Bastian Schilling , Derek Liu , Antje Sucker , Elisabeth Livingstone , Livnat Jerby-Arnon , Lisa Zimmer , Ralf Gutzmer , Imke Satzger , Carmen Loquai , Stephan Grabbe , Natalie Vokes , Claire A Margolis , Jake Conway , Meng Xiao He , Haitham Elmarakeby , Felix Dietlein , Diana Miao , Adam Tracy , Helen Gogas , Simone M Goldinger , Jochen Utikal , Christian U Blank , Ricarda Rauschenberg , Dagmar von Bubnoff , Angela Krackhardt , Benjamin Weide , Sebastian Haferkamp , Felix Kiecker , Ben Izar , Levi Garraway , Aviv Regev , Keith Flaherty , Annette Paschen , Eliezer M Van Allen , Dirk Schadendorf

Chondroitin polymerizing factor (CHPF) promotes development of malignant melanoma through regulation of CDK1.

Cell death & disease

Avec: Wei Sun , Fang Zhao , Yu Xu , Kai Huang , Xianling Guo , Biqiang Zheng , Xin Liu , Zhiguo Luo , Yunyi Kong , Midie Xu , Dirk Schadendorf , Yong Chen

Adjuvant therapy with pegylated interferon-alfa2b vs observation in stage II B/C patients with ulcerated primary: Results of the European Organisation for Research and Treatment of Cancer 18081 randomised trial.

European journal of cancer (Oxford, England : 1990)

Avec: Alexander M M Eggermont , Piotr Rutkowski , Caroline Dutriaux , Rainer Hofman-Wellenhof , Peter Dziewulski , Maria Marples , Floren Grange , Catherine Lok , Elisabetta Pennachioli , Caroline Robert , Alexander C J van Akkooi , Lars Bastholt , Alessandro Minisini , Ernest Marshall , François Salès , Jean-Jacques Grob , Oliver Bechter , Dirk Schadendorf , Sandrine Marreaud , Michal Kicinski , Stefan Suciu , Alessandro A E Testori

Overall survival at 5 years of follow-up in a phase III trial comparing ipilimumab 10 mg/kg with 3 mg/kg in patients with advanced melanoma.

Journal for immunotherapy of cancer

Avec: Paolo Antonio Ascierto , Michele Del Vecchio , Andrzej Mackiewicz , Caroline Robert , Vanna Chiarion-Sileni , Ana Arance , Céleste Lebbé , Inge Marie Svane , Catriona McNeil , Piotr Rutkowski , Carmen Loquai , Laurent Mortier , Omid Hamid , Lars Bastholt , Brigitte Dreno , Dirk Schadendorf , Claus Garbe , Marta Nyakas , Jean-Jacques Grob , Luc Thomas , Gabriella Liszkay , Michael Smylie , Christoph Hoeller , Virginia Ferraresi , Florent Grange , Ralf Gutzmer , Joanna Pikiel , Fareeda Hosein , Burcin Simsek , Michele Maio

Author Correction: Tertiary lymphoid structures improve immunotherapy and survival in melanoma.

Nature

Avec: Rita Cabrita , Martin Lauss , Adriana Sanna , Marco Donia , Mathilde Skaarup Larsen , Shamik Mitra , Iva Johansson , Bengt Phung , Katja Harbst , Johan Vallon-Christersson , Alison van Schoiack , Kristina Lövgren , Sarah Warren , Karin Jirström , Håkan Olsson , Kristian Pietras , Christian Ingvar , Karolin Isaksson , Dirk Schadendorf , Henrik Schmidt , Lars Bastholt , Ana Carneiro , Jennifer A Wargo , Inge Marie Svane , Göran Jönsson

Drug-induced sarcoidosis-like reaction in adjuvant immunotherapy: Increased rate and mimicker of metastasis.

European journal of cancer (Oxford, England : 1990)

Avec: Eleftheria Chorti , Theodora Kanaki , Lisa Zimmer , Eva Hadaschik , Selma Ugurel , Emmanouil Gratsias , Alexander Roesch , Francesco Bonella , Thomas E Wessendorf , Julia Wälscher , Dirk Theegarten , Dirk Schadendorf , Elisabeth Livingstone

Vitiligo expansion and extent correlate with durable response in anti-programmed death 1 antibody treatment for advanced melanoma: A multi-institutional retrospective study.

The Journal of dermatology

Avec: Taisuke Matsuya , Yasuhiro Nakamura , Shigeto Matsushita , Ryota Tanaka , Yukiko Teramoto , Yuri Asami , Jiro Uehara , Megumi Aoki , Kentaro Yamamura , Yoshiyuki Nakamura , Yasuhiro Fujisawa , Elisabeth Livingstone , Lisa Zimmer , Dirk Schadendorf , Hiroshi Kagamu , Manabu Fujimoto , Masaru Honma , Akemi Ishida-Yamamoto , Ryuichiro Araki , Akifumi Yamamoto

Long-term outcomes in patients with BRAF V600-mutant metastatic melanoma receiving dabrafenib monotherapy: Analysis from phase 2 and 3 clinical trials.

European journal of cancer (Oxford, England : 1990)

Avec: Axel Hauschild , Paolo A Ascierto , Dirk Schadendorf , Jean Jacques Grob , Antoni Ribas , Felix Kiecker , Caroline Dutriaux , Lev V Demidov , Céleste Lebbé , Piotr Rutkowski , Christian U Blank , Ralf Gutzmer , Michael Millward , Richard Kefford , Tomas Haas , Anthony D'Amelio , Eduard Gasal , Bijoyesh Mookerjee , Paul B Chapman

GNAQ and GNA11 mutant nonuveal melanoma: a subtype distinct from both cutaneous and uveal melanoma.

The British journal of dermatology

Avec: E Livingstone , A Zaremba , S Horn , S Ugurel , B Casalini , M Schlaak , J C Hassel , R Herbst , J S Utikal , B Weide , R Gutzmer , F Meier , C Koelsche , E Hadaschik , A Sucker , H Reis , S Merkelbach-Bruse , M Siewert , F Sahm , A von Deimling , I Cosgarea , L Zimmer , D Schadendorf , B Schilling , K G Griewank

Macrophages/Microglia Represent the Major Source of Indolamine 2,3-Dioxygenase Expression in Melanoma Metastases of the Brain.

Frontiers in immunology

Avec: Dayana Herrera-Rios , Sadaf S Mughal , Sarah Teuber-Hanselmann , Daniela Pierscianek , Antje Sucker , Philipp Jansen , Tobias Schimming , Joachim Klode , Julia Reifenberger , Jörg Felsberg , Kathy Keyvani , Benedikt Brors , Ulrich Sure , Guido Reifenberger , Dirk Schadendorf , Iris Helfrich

Metastatic Merkel cell carcinoma and myasthenia gravis: contraindication for therapy with immune checkpoint inhibitors?

Journal for immunotherapy of cancer

Avec: Anne Zaremba , Eleftheria Chorti , Finja Jockenhöfer , Saskia Bolz , Selma Sirin , Martin Glas , Jürgen C Becker , Selma Ugurel , Alexander Roesch , Dirk Schadendorf , Elisabeth Livingstone , Tim Hagenacker , Lisa Zimmer

Cardiovascular Adverse Events Associated With BRAF and MEK Inhibitors: A Systematic Review and Meta-analysis.

JAMA network open

Avec: Raluca I Mincu , Amir A Mahabadi , Lars Michel , Simone M Mrotzek , Dirk Schadendorf , Tienush Rassaf , Matthias Totzeck

Impact of American Joint Committee on Cancer 8th edition classification on staging and survival of patients with melanoma.

European journal of cancer (Oxford, England : 1990)

Avec: Theodora Kanaki , Andreas Stang , Ralf Gutzmer , Lisa Zimmer , Eleftheria Chorti , Antje Sucker , Selma Ugurel , Eva Hadaschik , Nikolai S Gräger , Imke Satzger , Dirk Schadendorf , Elisabeth Livingstone

B-type natriuretic peptides for the prediction of cardiovascular events and mortality in patients living with HIV: Results from the HIV-HEART study.

International journal of cardiology

Avec: Nico Reinsch , Hendrik Streeck , Volker Holzendorf , Christina Schulze , Till Neumann , Norbert H Brockmeyer , Jan Kehrmann , Dirk Schadendorf , Stefan Esser , Auteur inconnu

Sequence-dependent cross-resistance of combined radiotherapy plus BRAF

European journal of cancer (Oxford, England : 1990)

Avec: B Shannan , J Matschke , H Chauvistré , F Vogel , D Klein , F Meier , D Westphal , J Bruns , R Rauschenberg , J Utikal , A Forschner , C Berking , P Terheyden , E Dabrowski , R Gutzmer , D Rafei-Shamsabadi , F Meiss , L Heinzerling , L Zimmer , Elisabeth Livingstone , Renáta Váraljai , A Hoewner , S Horn , J Klode , M Stuschke , B Scheffler , A Marchetto , G Sannino , T G P Grünewald , D Schadendorf , V Jendrossek , A Roesch

Evaluation of Two Dosing Regimens for Nivolumab in Combination With Ipilimumab in Patients With Advanced Melanoma: Results From the Phase IIIb/IV CheckMate 511 Trial.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Celeste Lebbé , Nicolas Meyer , Laurent Mortier , Ivan Marquez-Rodas , Caroline Robert , Piotr Rutkowski , Alexander M Menzies , Thomas Eigentler , Paolo A Ascierto , Michael Smylie , Dirk Schadendorf , Mazhar Ajaz , Inge Marie Svane , Rene Gonzalez , Linda Rollin , Jennifer Lord-Bessen , Abdel Saci , Elena Grigoryeva , Jacopo Pigozzo

Unmet information needs of patients with melanoma in Germany.

Melanoma research

Avec: Julia Brütting , Maike Bergmann , Marlene Garzarolli , Ricarda Rauschenberg , Christiane Weber , Carola Berking , Wolfgang Tilgen , Dirk Schadendorf , Friedegund Meier , Auteur inconnu

[Cutaneous angiosarcoma clinically presenting as Quincke's edema].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete

Avec: M Albrecht , E Hadaschik , L Zimmer , E Livingstone , R Hamacher , S Bauer , D Schadendorf , S Ugurel

Durable Complete Response in a Melanoma Patient With Unknown Primary, Associated With Sequential and Severe Multi-Organ Toxicity After a Single Dose of CTLA-4 Plus PD-1 Blockade: A Case Report.

Frontiers in oncology

Avec: Johanna Matull , Elisabeth Livingstone , Axel Wetter , Lisa Zimmer , Anne Zaremba , Harald Lahner , Dirk Schadendorf , Selma Ugurel

Rationale for Immune Checkpoint Inhibitors Plus Targeted Therapy in Metastatic Melanoma: A Review.

JAMA oncology

Avec: Reinhard Dummer , Paolo A Ascierto , Paul Nathan , Caroline Robert , Dirk Schadendorf

Combined PD-1, BRAF and MEK inhibition in advanced BRAF-mutant melanoma: safety run-in and biomarker cohorts of COMBI-i.

Nature medicine

Avec: Reinhard Dummer , Celeste Lebbé , Victoria Atkinson , Mario Mandalà , Paul D Nathan , Ana Arance , Erika Richtig , Naoya Yamazaki , Caroline Robert , Dirk Schadendorf , Hussein A Tawbi , Paolo A Ascierto , Antoni Ribas , Keith T Flaherty , Neha Pakhle , Catarina D Campbell , Daniel Gusenleitner , Aisha Masood , Jan C Brase , Eduard Gasal , Georgina V Long

Robustness of convolutional neural networks in recognition of pigmented skin lesions.

European journal of cancer (Oxford, England : 1990)

Avec: Roman C Maron , Sarah Haggenmüller , Christof von Kalle , Jochen S Utikal , Friedegund Meier , Frank F Gellrich , Axel Hauschild , Lars E French , Max Schlaak , Kamran Ghoreschi , Heinz Kutzner , Markus V Heppt , Sebastian Haferkamp , Wiebke Sondermann , Dirk Schadendorf , Bastian Schilling , Achim Hekler , Eva Krieghoff-Henning , Jakob N Kather , Stefan Fröhling , Daniel B Lipka , Titus J Brinker

Clinical impact of COVID-19 on patients with cancer treated with immune checkpoint inhibition.

Journal for immunotherapy of cancer

Avec: Aljosja Rogiers , Ines Pires da Silva , Chiara Tentori , Carlo Alberto Tondini , Joseph M Grimes , Megan H Trager , Sharon Nahm , Leyre Zubiri , Michael Manos , Peter Bowling , Arielle Elkrief , Neha Papneja , Maria Grazia Vitale , April A N Rose , Jessica S W Borgers , Severine Roy , Joanna Mangana , Thiago Pimentel Muniz , Tim Cooksley , Jeremy Lupu , Alon Vaisman , Samuel D Saibil , Marcus O Butler , Alexander M Menzies , Matteo S Carlino , Michael Erdmann , Carola Berking , Lisa Zimmer , Dirk Schadendorf , Laura Pala , Paola Queirolo , Christian Posch , Axel Hauschild , Reinhard Dummer , John Haanen , Christian U Blank , Caroline Robert , Ryan J Sullivan , Paolo Antonio Ascierto , Wilson H Miller , F Stephen Hodi , Karijn P M Suijkerbuijk , Kerry L Reynolds , Osama E Rahma , Paul C Lorigan , Richard D Carvajal , Serigne Lo , Mario Mandala , Georgina V Long

Comparison of mutation profiles in primary melanomas and corresponding nodal naevi using next-generation sequencing.

Clinical and experimental dermatology

Avec: T Gambichler , E-M Rohrmoser , K Horny , A Sucker , D Schadendorf , M Skrygan , L Susok , M Stücker , J C Becker

High-resolution three-dimensional imaging for precise staging in melanoma.

European journal of cancer (Oxford, England : 1990)

Avec: Simon F Merz , Philipp Jansen , Ricarda Ulankiewicz , Lea Bornemann , Tobias Schimming , Klaus Griewank , Zülal Cibir , Andreas Kraus , Ingo Stoffels , Timo Aspelmeier , Sven Brandau , Dirk Schadendorf , Eva Hadaschik , Gernot Ebel , Matthias Gunzer , Joachim Klode

Integrated analysis of a phase 2 study of cemiplimab in advanced cutaneous squamous cell carcinoma: extended follow-up of outcomes and quality of life analysis.

Journal for immunotherapy of cancer

Avec: Danny Rischin , Nikhil I Khushalani , Chrysalyne D Schmults , Alexander Guminski , Anne Lynn S Chang , Karl D Lewis , Annette M Lim , Leonel Hernandez-Aya , Brett G M Hughes , Dirk Schadendorf , Axel Hauschild , Alesha A Thai , Elizabeth Stankevich , Jocelyn Booth , Suk-Young Yoo , Siyu Li , Zhen Chen , Emmanuel Okoye , Chieh-I Chen , Vera Mastey , Medha Sasane , Israel Lowy , Matthew G Fury , Michael R Migden

TERT promoter mutations are associated with longer progression-free and overall survival in patients with BRAF-mutant melanoma receiving BRAF and MEK inhibitor therapy.

European journal of cancer (Oxford, England : 1990)

Avec: Carl M Thielmann , Johanna Matull , Anne Zaremba , Rajmohan Murali , Eleftheria Chorti , Georg Lodde , Philipp Jansen , Rudolf Herbst , Patrick Terheyden , Jochen Utikal , Claudia Pföhler , Jens Ulrich , Alexander Kreuter , Peter Mohr , Ralf Gutzmer , Friedegund Meier , Edgar Dippel , Michael Weichenthal , Julia Kretz , Inga Möller , Antje Sucker , Annette Paschen , Elisabeth Livingstone , Lisa Zimmer , Eva Hadaschik , Selma Ugurel , Dirk Schadendorf , Klaus G Griewank

Relatlimab and Nivolumab versus Nivolumab in Untreated Advanced Melanoma.

The New England journal of medicine

Avec: Hussein A Tawbi , Dirk Schadendorf , Evan J Lipson , Paolo A Ascierto , Luis Matamala , Erika Castillo Gutiérrez , Piotr Rutkowski , Helen J Gogas , Christopher D Lao , Juliana Janoski De Menezes , Stéphane Dalle , Ana Arance , Jean-Jacques Grob , Shivani Srivastava , Mena Abaskharoun , Melissa Hamilton , Sarah Keidel , Katy L Simonsen , Anne Marie Sobiesk , Bin Li , F Stephen Hodi , Georgina V Long , Auteur inconnu

Real-World Therapy with Pembrolizumab: Outcomes and Surrogate Endpoints for Predicting Survival in Advanced Melanoma Patients in Germany.

Cancers

Avec: Peter Mohr , Emilie Scherrer , Chalid Assaf , Marc Bender , Carola Berking , Sheenu Chandwani , Thomas Eigentler , Imke Grimmelmann , Ralf Gutzmer , Sebastian Haferkamp , Jessica C Hassel , Axel Hauschild , Rudolf Herbst , Ruixuan Jiang , Katharina C Kähler , Clemens Krepler , Alexander Kreuter , Ulrike Leiter , Carmen Loquai , Friedegund Meier , Claudia Pföhler , Anja Rudolph , Dirk Schadendorf , Maximo Schiavone , Gaston Schley , Patrick Terheyden , Selma Ugurel , Jens Ulrich , Jochen Utikal , Carsten Weishaupt , Julia Welzel , Michael Weichenthal

Immune Checkpoint Blockade for Metastatic Uveal Melanoma: Re-Induction following Resistance or Toxicity.

Cancers

Avec: Elias A T Koch , Anne Petzold , Anja Wessely , Edgar Dippel , Anja Gesierich , Ralf Gutzmer , Jessica C Hassel , Sebastian Haferkamp , Katharina C Kähler , Harald Knorr , Nicole Kreuzberg , Ulrike Leiter , Carmen Loquai , Friedegund Meier , Markus Meissner , Peter Mohr , Claudia Pföhler , Farnaz Rahimi , Dirk Schadendorf , Beatrice Schell , Max Schlaak , Patrick Terheyden , Kai-Martin Thoms , Beatrice Schuler-Thurner , Selma Ugurel , Jens Ulrich , Jochen Utikal , Michael Weichenthal , Fabian Ziller , Carola Berking , Markus V Heppt

Persister state-directed transitioning and vulnerability in melanoma.

Nature communications

Avec: Heike Chauvistré , Batool Shannan , Sheena M Daignault-Mill , Robert J Ju , Daniel Picard , Stefanie Egetemaier , Renáta Váraljai , Christine S Gibhardt , Antonio Sechi , Farnusch Kaschani , Oliver Keminer , Samantha J Stehbens , Qin Liu , Xiangfan Yin , Kirujan Jeyakumar , Felix C E Vogel , Clemens Krepler , Vito W Rebecca , Linda Kubat , Smiths S Lueong , Jan Forster , Susanne Horn , Marc Remke , Michael Ehrmann , Annette Paschen , Jürgen C Becker , Iris Helfrich , Daniel Rauh , Markus Kaiser , Sheraz Gul , Meenhard Herlyn , Ivan Bogeski , José Neptuno Rodríguez-López , Nikolas K Haass , Dirk Schadendorf , Alexander Roesch

Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity.

Journal for immunotherapy of cancer

Avec: Beatrice Thier , Fang Zhao , Simone Stupia , Alicia Brüggemann , Johannes Koch , Nina Schulze , Susanne Horn , Christoph Coch , Gunther Hartmann , Antje Sucker , Dirk Schadendorf , Annette Paschen

MEK inhibitors for pre-treated, NRAS-mutated metastatic melanoma: A multi-centre, retrospective study.

European journal of cancer (Oxford, England : 1990)

Avec: Martin Salzmann , Johannes Pawlowski , Carmen Loquai , David A Rafei-Shamsabadi , Frank Meiss , Selma Ugurel , Dirk Schadendorf , Friedegund Meier , Alexander H Enk , Jessica C Hassel

Adjuvant pembrolizumab versus placebo in resected high-risk stage II melanoma: Health-related quality of life from the randomized phase 3 KEYNOTE-716 study.

European journal of cancer (Oxford, England : 1990)

Avec: Muhammad A Khattak , Jason J Luke , Georgina V Long , Paolo A Ascierto , Piotr Rutkowski , Dirk Schadendorf , Caroline Robert , Jean-Jacques Grob , Luis de la Cruz Merino , Michele Del Vecchio , Francesco Spagnolo , Jacek Mackiewicz , Vanna Chiarion-Sileni , Matteo S Carlino , Peter Mohr , Federica De Galitiis , Merrick I Ross , Zeynep Eroglu , Ke Chen , Ruixuan Jiang , Mizuho Fukunaga-Kalabis , Clemens Krepler , Alexander M M Eggermont , John M Kirkwood

Efficacy and safety of immune checkpoint inhibitors in young adults with metastatic melanoma.

European journal of cancer (Oxford, England : 1990)

Avec: Selina K Wong , Steven M Blum , Xiaopeng Sun , Inês P Da Silva , Leyre Zubiri , Fei Ye , Kun Bai , Kevin Zhang , Selma Ugurel , Lisa Zimmer , Elisabeth Livingstone , Dirk Schadendorf , Patricio Serra-Bellver , Eva Muñoz-Couselo , Carolina Ortiz , Julia Lostes , Roberto M Huertas , Ana Arance , Lisa Pickering , Georgina V Long , Matteo S Carlino , Elizabeth I Buchbinder , Leticia Vázquez-Cortés , Diego Jara-Casas , Iván Márquez-Rodas , Iván R González-Espinoza , Justin M Balko , Alexander M Menzies , Ryan J Sullivan , Douglas B Johnson

The Latest Option: Nivolumab and Relatlimab in Advanced Melanoma.

Current oncology reports

Avec: Lea Jessica Albrecht , Elisabeth Livingstone , Lisa Zimmer , Dirk Schadendorf

Alternatives and reduced need for sentinel lymph node biopsy (SLNB) staging for melanoma.

European journal of cancer (Oxford, England : 1990)

Avec: Alexander C J van Akkooi , Dirk Schadendorf , Alexander M M Eggermont

Brain metastasis and survival outcomes after first-line therapy in metastatic melanoma: a multicenter DeCOG study on 1704 patients from the prospective skin cancer registry ADOREG.

Journal for immunotherapy of cancer

Avec: Cindy Franklin , Peter Mohr , Leonie Bluhm , Friedegund Meier , Marlene Garzarolli , Michael Weichenthal , Katharina Kähler , Imke Grimmelmann , Ralf Gutzmer , Jochen Utikal , Patrick Terheyden , Rudolf Herbst , Sebastian Haferkamp , Claudia Pfoehler , Andrea Forschner , Ulrike Leiter , Fabian Ziller , Frank Meiss , Jens Ulrich , Alexander Kreuter , Christoffer Gebhardt , Julia Welzel , Bastian Schilling , Martin Kaatz , Karin Scharfetter-Kochanek , Edgar Dippel , Dorothee Nashan , Michael Sachse , Carsten Weishaupt , Harald Löffler , Thilo Gambichler , Carmen Loquai , Lucie Heinzerling , Stephan Grabbe , Dirk Debus , Gaston Schley , Jessica C Hassel , Gerhard Weyandt , Maike Trommer , Georg Lodde , Jan-Malte Placke , Lisa Zimmer , Elisabeth Livingstone , Jürgen Christian Becker , Susanne Horn , Dirk Schadendorf , Selma Ugurel

Immune checkpoint inhibition in patients with NRAS mutated and NRAS wild type melanoma: a multicenter Dermatologic Cooperative Oncology Group study on 637 patients from the prospective skin cancer registry ADOREG.

European journal of cancer (Oxford, England : 1990)

Avec: Anne Zaremba , Peter Mohr , Ralf Gutzmer , Friedegund Meier , Claudia Pföhler , Michael Weichenthal , Patrick Terheyden , Andrea Forschner , Ulrike Leiter , Jens Ulrich , Jochen Utikal , Julia Welzel , Martin Kaatz , Christoffer Gebhardt , Rudolf Herbst , Anca Sindrilaru , Edgar Dippel , Michael Sachse , Frank Meiss , Lucie Heinzerling , Sebastian Haferkamp , Carsten Weishaupt , Harald Löffler , Sophia Kreft , Klaus Griewank , Elisabeth Livingstone , Dirk Schadendorf , Selma Ugurel , Lisa Zimmer

Health-related quality of life with nivolumab plus relatlimab versus nivolumab monotherapy in patients with previously untreated unresectable or metastatic melanoma: RELATIVITY-047 trial.

European journal of cancer (Oxford, England : 1990)

Avec: Dirk Schadendorf , Hussein Tawbi , Evan J Lipson , F Stephen Hodi , Piotr Rutkowski , Helen Gogas , Christopher D Lao , Jean-Jacques Grob , Andriy Moshyk , Jennifer Lord-Bessen , Melissa Hamilton , Shien Guo , Ling Shi , Sarah Keidel , Georgina V Long

Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses.

Immunity

Avec: Felix Bayerl , Philippa Meiser , Sainitin Donakonda , Anna Hirschberger , Sebastian B Lacher , Anna-Marie Pedde , Chris D Hermann , Anais Elewaut , Moritz Knolle , Lukas Ramsauer , Thomas J Rudolph , Simon Grassmann , Rupert Öllinger , Nicole Kirchhammer , Marcel Trefny , Martina Anton , Dirk Wohlleber , Bastian Höchst , Anne Zaremba , Achim Krüger , Roland Rad , Anna C Obenauf , Dirk Schadendorf , Alfred Zippelius , Veit R Buchholz , Barbara U Schraml , Jan P Böttcher

Falling off the screening grid-Predictors for postponed utilization of psycho-oncological support in cancer patients and its implications for distress assessment and management.

Psycho-oncology

Avec: Raya Rausch , Alexander Bäuerle , Vanessa Rentrop , Christoph Jansen , Felix Nensa , Stefan Palm , Mitra Tewes , Dirk Schadendorf , Eva-Maria Skoda , Martin Teufel

Long-term outcomes and persistent toxicities following BRAF/MEK inhibitor therapy for advanced melanoma.

European journal of cancer (Oxford, England : 1990)

Avec: Rachel S Goodman , Lorenza Di Guardo , Andrea Maurichi , Brendan Kirwin , Adnan Khattak , Vito Vanella , Joanna Lee , Aleigha Lawless , Juliane Czapla , Andrea Spagnoletti , Margherita Ambrosini , Elisabeth Livingstone , Georgina V Long , Ryan J Sullivan , Matteo S Carlino , Victoria Atkinson , Claudia Trojanello , Paolo A Ascierto , Dirk Schadendorf , Lydia Warburton , Alexander M Menzies , Mario Santinami , Douglas B Johnson

COMBI-r: A Prospective, Non-Interventional Study of Dabrafenib Plus Trametinib in Unselected Patients with Unresectable or Metastatic BRAF V600-Mutant Melanoma.

Cancers

Avec: Carola Berking , Elisabeth Livingstone , Dirk Debus , Carmen Loquai , Michael Weichenthal , Ulrike Leiter , Felix Kiecker , Peter Mohr , Thomas K Eigentler , Janina Remy , Katharina Schober , Markus V Heppt , Imke von Wasielewski , Dirk Schadendorf , Ralf Gutzmer

Five-Year Analysis of Adjuvant Pembrolizumab or Placebo in Stage III Melanoma.

NEJM evidence

Avec: Alexander M M Eggermont , Michal Kicinski , Christian U Blank , Mario Mandala , Georgina V Long , Victoria Atkinson , Stéphane Dalle , Andrew Haydon , Andrey Meshcheryakov , Adnan Khattak , Matteo S Carlino , Shahneen Sandhu , James Larkin , Susana Puig , Paolo A Ascierto , Piotr Rutkowski , Dirk Schadendorf , Marye Boers-Sonderen , Anna Maria Di Giacomo , Alfonsus J M van den Eertwegh , Jean-Jacques Grob , Ralf Gutzmer , Rahima Jamal , Alexander C J van Akkooi , Paul Lorigan , Dmitri Grebennik , Clemens Krepler , Sandrine Marreaud , Stefan Suciu , Caroline Robert

Overall Survival and Response with Nivolumab and Relatlimab in Advanced Melanoma.

NEJM evidence

Avec: Georgina V Long , F Stephen Hodi , Evan J Lipson , Dirk Schadendorf , Paolo A Ascierto , Luis Matamala , Pamela Salman , Erika Castillo Gutiérrez , Piotr Rutkowski , Helen J Gogas , Christopher D Lao , Juliana Janoski De Menezes , Stéphane Dalle , Ana Arance , Jean-Jacques Grob , Sarah Keidel , Anadil Shaikh , Anne Marie Sobiesk , Sonia Dolfi , Hussein A Tawbi

Deep learning based histological classification of adnex tumors.

European journal of cancer (Oxford, England : 1990)

Avec: Philipp Jansen , Jean Le'Clerc Arrastia , Daniel Otero Baguer , Maximilian Schmidt , Jennifer Landsberg , Jörg Wenzel , Michael Emberger , Dirk Schadendorf , Eva Hadaschik , Peter Maass , Klaus Georg Griewank

Determining the cut-off value for the Minimal Documentation System (MIDOS2) screening tool to initiate specialized palliative care based on patient's subjective need for palliative support and symptom burden in inpatients with advanced cancer.

Journal of cancer research and clinical oncology

Avec: Anna Heinzelmann , Mitra Tewes , Sandy Müller , Ulrich Sure , Ken Herrmann , Dirk Schadendorf , Eva Warnecke , Raya Rausch , Eva-Maria Skoda , Maria Rosa Salvador Comino

Interdisciplinary management of skin cancer.

Laryngo- rhino- otologie

Avec: Victoria Rudolph , Anna-Sophia Leven , Robin Eisenburger , Dirk Schadendorf , Susanne Wiegand

Anti-PD-1 alone or in combination with anti-CTLA-4 for advanced melanoma patients with liver metastases.

European journal of cancer (Oxford, England : 1990)

Avec: Ines Pires da Silva , Isabel Li , Selma Ugurel , Patricio Serra-Bellver , Avanti Andhale , Hannah Burnette , Francisco Aya , Jordan W Conway , Jorja Braden , Matteo S Carlino , Alexander M Menzies , Michael Weichenthal , Peter Mohr , Ralf Gutzmer , Ana M Arance , Douglas B Johnson , Paul Lorigan , Dirk Schadendorf , Serigne N Lo , Georgina V Long

Requirements for a dashboard optimized for melanoma patient care through user-centered context exploration.

Scientific reports

Avec: Eva Maria Hartmann , Alisa Küper , Jessica Swoboda , Georg Christian Lodde , Elisabeth Livingstone , Catharina Lena Beckmann , Dirk Schadendorf , Sabine Sachweh

A phase 2 open-label study of cemiplimab in patients with advanced cutaneous squamous cell carcinoma (EMPOWER-CSCC-1): Final long-term analysis of Groups 1, 2, and 3, and primary analysis of fixed-dose treatment Group 6.

Journal of the American Academy of Dermatology

Avec: Brett G M Hughes , Alexander Guminski , Samantha Bowyer , Michael R Migden , Chrysalyne D Schmults , Nikhil I Khushalani , Anne Lynn S Chang , Jean-Jacques Grob , Karl D Lewis , George Ansstas , Fiona Day , Rahul Ladwa , Brian N Stein , Eva Muñoz Couselo , Friedegund Meier , Axel Hauschild , Dirk Schadendorf , Nicole Basset-Seguin , Badri Modi , Sophie Dalac-Rat , Lara A Dunn , Lukas Flatz , Laurent Mortier , Sarah Guégan , Lucie M Heinzerling , Janice M Mehnert , Sabiha Trabelsi , Ainara Soria-Rivas , Alexander J Stratigos , Claas Ulrich , Deborah J Wong , Marie Beylot-Barry , Paolo Bossi , Cristina Bugés Sánchez , Sunandana Chandra , Caroline Robert , Jeffery S Russell , Ann W Silk , Jocelyn Booth , Suk-Young Yoo , Frank Seebach , Israel Lowy , Matthew G Fury , Danny Rischin

Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced Melanoma.

The New England journal of medicine

Avec: Jedd D Wolchok , Vanna Chiarion-Sileni , Piotr Rutkowski , C Lance Cowey , Dirk Schadendorf , John Wagstaff , Paola Queirolo , Reinhard Dummer , Marcus O Butler , Andrew G Hill , Michael A Postow , Caroline Gaudy-Marqueste , Theresa Medina , Christopher D Lao , John Walker , Iván Márquez-Rodas , John B A G Haanen , Massimo Guidoboni , Michele Maio , Patrick Schöffski , Matteo S Carlino , Shahneen Sandhu , Céleste Lebbé , Paolo A Ascierto , Georgina V Long , Corey Ritchings , Ayman Nassar , Margarita Askelson , Melanie Pe Benito , Wenjia Wang , F Stephen Hodi , James Larkin , Auteur inconnu

Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility.

Nature genetics

Avec: Maria Teresa Landi , D Timothy Bishop , Stuart MacGregor , Mitchell J Machiela , Alexander J Stratigos , Paola Ghiorzo , Myriam Brossard , Donato Calista , Jiyeon Choi , Maria Concetta Fargnoli , Tongwu Zhang , Monica Rodolfo , Adam J Trower , Chiara Menin , Jacobo Martinez , Andreas Hadjisavvas , Lei Song , Irene Stefanaki , Richard Scolyer , Rose Yang , Alisa M Goldstein , Miriam Potrony , Katerina P Kypreou , Lorenza Pastorino , Paola Queirolo , Cristina Pellegrini , Laura Cattaneo , Matthew Zawistowski , Pol Gimenez-Xavier , Arantxa Rodriguez , Lisa Elefanti , Siranoush Manoukian , Licia Rivoltini , Blair H Smith , Maria A Loizidou , Laura Del Regno , Daniela Massi , Mario Mandala , Kiarash Khosrotehrani , Lars A Akslen , Christopher I Amos , Per A Andresen , Marie-Françoise Avril , Esther Azizi , H Peter Soyer , Veronique Bataille , Bruna Dalmasso , Lisa M Bowdler , Kathryn P Burdon , Wei V Chen , Veryan Codd , Jamie E Craig , Tadeusz Dębniak , Mario Falchi , Shenying Fang , Eitan Friedman , Sarah Simi , Pilar Galan , Zaida Garcia-Casado , Elizabeth M Gillanders , Scott Gordon , Adele Green , Nelleke A Gruis , Johan Hansson , Mark Harland , Jessica Harris , Per Helsing , Anjali Henders , Marko Hočevar , Veronica Höiom , David Hunter , Christian Ingvar , Rajiv Kumar , Julie Lang , G Mark Lathrop , Jeffrey E Lee , Xin Li , Jan Lubiński , Rona M Mackie , Maryrose Malt , Josep Malvehy , Kerrie McAloney , Hamida Mohamdi , Anders Molven , Eric K Moses , Rachel E Neale , Srdjan Novaković , Dale R Nyholt , Håkan Olsson , Nicholas Orr , Lars G Fritsche , Joan Anton Puig-Butille , Abrar A Qureshi , Graham L Radford-Smith , Juliette Randerson-Moor , Celia Requena , Casey Rowe , Nilesh J Samani , Marianna Sanna , Dirk Schadendorf , Hans-Joachim Schulze , Lisa A Simms , Mark Smithers , Fengju Song , Anthony J Swerdlow , Nienke van der Stoep , Nicole A Kukutsch , Alessia Visconti , Leanne Wallace , Sarah V Ward , Lawrie Wheeler , Richard A Sturm , Amy Hutchinson , Kristine Jones , Michael Malasky , Aurelie Vogt , Weiyin Zhou , Karen A Pooley , David E Elder , Jiali Han , Belynda Hicks , Nicholas K Hayward , Peter A Kanetsky , Chad Brummett , Grant W Montgomery , Catherine M Olsen , Caroline Hayward , Alison M Dunning , Nicholas G Martin , Evangelos Evangelou , Graham J Mann , Georgina Long , Paul D P Pharoah , Douglas F Easton , Jennifer H Barrett , Anne E Cust , Goncalo Abecasis , David L Duffy , David C Whiteman , Helen Gogas , Arcangela De Nicolo , Margaret A Tucker , Julia A Newton-Bishop , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Ketty Peris , Stephen J Chanock , Florence Demenais , Kevin M Brown , Susana Puig , Eduardo Nagore , Jianxin Shi , Mark M Iles , Matthew H Law

Effect of a Face-Aging Mobile App-Based Intervention on Skin Cancer Protection Behavior in Secondary Schools in Brazil: A Cluster-Randomized Clinical Trial.

JAMA dermatology

Avec: Titus J Brinker , Bianca Lisa Faria , Olber Moreira de Faria , Joachim Klode , Dirk Schadendorf , Jochen S Utikal , Ute Mons , Eva Krieghoff-Henning , Oscar Campos Lisboa , Ana Carla Cruz Oliveira , Henrique Augusto Lino , Breno Bernardes-Souza

Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology.

PLoS pathogens

Avec: Paul David , Malgorzata Drabczyk-Pluta , Eva Pastille , Torben Knuschke , Tanja Werner , Nadine Honke , Dominik A Megger , Ilseyar Akhmetzyanova , Namir Shaabani , Annette Eyking-Singer , Elke Cario , Olivia Kershaw , Achim D Gruber , Matthias Tenbusch , Kirsten K Dietze , Mirko Trilling , Jia Liu , Dirk Schadendorf , Hendrik Streeck , Karl S Lang , Youhua Xie , Lisa Zimmer , Barbara Sitek , Annette Paschen , Astrid M Westendorf , Ulf Dittmer , Gennadiy Zelinskyy

Oncocardiology: new challenges, new opportunities.

Herz

Avec: Lars Michel , Dirk Schadendorf , Tienush Rassaf

Adjuvant nivolumab plus ipilimumab or nivolumab monotherapy versus placebo in patients with resected stage IV melanoma with no evidence of disease (IMMUNED): a randomised, double-blind, placebo-controlled, phase 2 trial.

Lancet (London, England)

Avec: Lisa Zimmer , Elisabeth Livingstone , Jessica C Hassel , Michael Fluck , Thomas Eigentler , Carmen Loquai , Sebastian Haferkamp , Ralf Gutzmer , Friedegund Meier , Peter Mohr , Axel Hauschild , Bastian Schilling , Christian Menzer , Felix Kieker , Edgar Dippel , Alexander Rösch , Jan-Christoph Simon , Beate Conrad , Silvia Körner , Christine Windemuth-Kieselbach , Leonora Schwarz , Claus Garbe , Jürgen C Becker , Dirk Schadendorf , Auteur inconnu

Association of BRAF V600E/K Mutation Status and Prior BRAF/MEK Inhibition With Pembrolizumab Outcomes in Advanced Melanoma: Pooled Analysis of 3 Clinical Trials.

JAMA oncology

Avec: Igor Puzanov , Antoni Ribas , Caroline Robert , Jacob Schachter , Marta Nyakas , Adil Daud , Ana Arance , Matteo S Carlino , Steven J O'Day , Georgina V Long , Kim A Margolin , Reinhard Dummer , Dirk Schadendorf , Jose Lutzky , Paolo A Ascierto , Ahmad Tarhini , Jianxin Lin , Robin Mogg , Blanca Homet Moreno , Nageatte Ibrahim , Omid Hamid

ECG Changes in Melanoma Patients Undergoing Cancer Therapy-Data From the ECoR Registry.

Journal of clinical medicine

Avec: Julia Pohl , Raluca-Ileana Mincu , Simone Maria Mrotzek , Lena Hinrichs , Lars Michel , Elisabeth Livingstone , Lisa Zimmer , Reza Wakili , Dirk Schadendorf , Tienush Rassaf , Matthias Totzeck

Retraction Note to: cGMP-phosphodiesterase 6, transducin and Wnt5a/Frizzled-2-signaling control cGMP and Ca

Cellular and molecular life sciences : CMLS

Avec: Alexandr V Bazhin , Vojtech Tambor , Boyan Dikov , Pavel P Philippov , Dirk Schadendorf , Stefan B Eichmüller

Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma.

Nature medicine

Five-Year Analysis of Adjuvant Dabrafenib plus Trametinib in Stage III Melanoma.

The New England journal of medicine

Avec: Reinhard Dummer , Axel Hauschild , Mario Santinami , Victoria Atkinson , Mario Mandalà , John M Kirkwood , Vanna Chiarion Sileni , James Larkin , Marta Nyakas , Caroline Dutriaux , Andrew Haydon , Caroline Robert , Laurent Mortier , Jacob Schachter , Thierry Lesimple , Ruth Plummer , Kohinoor Dasgupta , Eduard Gasal , Monique Tan , Georgina V Long , Dirk Schadendorf

Efficacy of PD-1-based immunotherapy after radiologic progression on targeted therapy in stage IV melanoma.

European journal of cancer (Oxford, England : 1990)

Avec: Sophia Kreft , Anja Gesierich , Thomas Eigentler , Cindy Franklin , Sara Valpione , Selma Ugurel , Jochen Utikal , Sebastian Haferkamp , Christian Blank , James Larkin , Claus Garbe , Dirk Schadendorf , Paul Lorigan , Bastian Schilling

Deep neural networks are superior to dermatologists in melanoma image classification.

European journal of cancer (Oxford, England : 1990)

Avec: Titus J Brinker , Achim Hekler , Alexander H Enk , Carola Berking , Sebastian Haferkamp , Axel Hauschild , Michael Weichenthal , Joachim Klode , Dirk Schadendorf , Tim Holland-Letz , Christof von Kalle , Stefan Fröhling , Bastian Schilling , Jochen S Utikal

Comparing artificial intelligence algorithms to 157 German dermatologists: the melanoma classification benchmark.

European journal of cancer (Oxford, England : 1990)

Avec: Titus J Brinker , Achim Hekler , Axel Hauschild , Carola Berking , Bastian Schilling , Alexander H Enk , Sebastian Haferkamp , Ante Karoglan , Christof von Kalle , Michael Weichenthal , Elke Sattler , Dirk Schadendorf , Maria R Gaiser , Joachim Klode , Jochen S Utikal

Patient-reported outcomes in patients with resected, high-risk melanoma with BRAF

The Lancet. Oncology

Avec: Dirk Schadendorf , Axel Hauschild , Mario Santinami , Victoria Atkinson , Mario Mandalà , Vanna Chiarion-Sileni , James Larkin , Marta Nyakas , Caroline Dutriaux , Andrew Haydon , Caroline Robert , Laurent Mortier , Thierry Lesimple , Ruth Plummer , Jacob Schachter , Kohinoor Dasgupta , Stephanie Manson , Roy Koruth , Bijoyesh Mookerjee , Richard Kefford , Reinhard Dummer , John M Kirkwood , Georgina V Long

Correction to: Long-term safety and efficacy of vismodegib in patients with advanced basal cell carcinoma: final update of the pivotal ERIVANCE BCC study.

BMC cancer

Avec: Aleksandar Sekulic , Michael R Migden , Nicole Basset-Seguin , Claus Garbe , Anja Gesierich , Christopher D Lao , Chris Miller , Laurent Mortier , Dedee F Murrell , Omid Hamid , Jorge F Quevedo , Jeannie Hou , Edward McKenna , Natalie Dimier , Sarah Williams , Dirk Schadendorf , Axel Hauschild , Auteur inconnu

Targeting the Atf7ip-Setdb1 Complex Augments Antitumor Immunity by Boosting Tumor Immunogenicity.

Cancer immunology research

Avec: Hai Hu , Alireza Khodadadi-Jamayran , Igor Dolgalev , Hyunwoo Cho , Sana Badri , Luis A Chiriboga , Briana Zeck , Miguel Lopez De Rodas Gregorio , Catríona M Dowling , Kristen Labbe , Jiehui Deng , Ting Chen , Hua Zhang , Paul Zappile , Ze Chen , Beatrix Ueberheide , Angeliki Karatza , Han Han , Michela Ranieri , Sittinon Tang , George Jour , Iman Osman , Antje Sucker , Dirk Schadendorf , Aristotelis Tsirigos , Kurt A Schalper , Vamsidhar Velcheti , Hsin-Yi Huang , Yujuan Jin , Hongbin Ji , John T Poirier , Fei Li , Kwok-Kin Wong

Male fertility during and after immune checkpoint inhibitor therapy: A cross-sectional pilot study.

European journal of cancer (Oxford, England : 1990)

Avec: Martin Salzmann , Georgi Tosev , Melanie Heck , Dirk Schadendorf , Imad Maatouk , Alexander H Enk , Martin Hartmann , Jessica C Hassel

Factors Influencing the Adjuvant Therapy Decision: Results of a Real-World Multicenter Data Analysis of 904 Melanoma Patients.

Cancers

Avec: Georg Lodde , Andrea Forschner , Jessica Hassel , Lena M Wulfken , Friedegund Meier , Peter Mohr , Katharina Kähler , Bastian Schilling , Carmen Loquai , Carola Berking , Svea Hüning , Kerstin Schatton , Christoffer Gebhardt , Julia Eckardt , Ralf Gutzmer , Lydia Reinhardt , Valerie Glutsch , Ulrike Nikfarjam , Michael Erdmann , Andreas Stang , Bernd Kowall , Alexander Roesch , Selma Ugurel , Lisa Zimmer , Dirk Schadendorf , Elisabeth Livingstone

Response to Combined Peptide Receptor Radionuclide Therapy and Checkpoint Immunotherapy with Ipilimumab Plus Nivolumab in Metastatic Merkel Cell Carcinoma.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Avec: Justin Ferdinandus , Wolfgang P Fendler , Katharina Lueckerath , Christoph Berliner , Sabine Kurzidem , Eva Hadaschik , Joachim Klode , Lisa Zimmer , Elisabeth Livingstone , Dirk Schadendorf , Ken Herrmann , Juergen C Becker , Selma Ugurel

Indirect treatment comparison of nivolumab versus placebo as adjuvant treatment for resected melanoma.

European journal of cancer (Oxford, England : 1990)

Avec: Jeffrey S Weber , Paolo A Ascierto , Mark R Middleton , Delphine Hennicken , Roberto Zoffoli , Anne Pieters , Adenike Amadi , Katrin Kupas , Srividya Kotapati , Andriy Moshyk , Dirk Schadendorf

Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Jedd D Wolchok , Vanna Chiarion-Sileni , Rene Gonzalez , Jean-Jacques Grob , Piotr Rutkowski , Christopher D Lao , C Lance Cowey , Dirk Schadendorf , John Wagstaff , Reinhard Dummer , Pier Francesco Ferrucci , Michael Smylie , Marcus O Butler , Andrew Hill , Ivan Márquez-Rodas , John B A G Haanen , Massimo Guidoboni , Michele Maio , Patrick Schöffski , Matteo S Carlino , Céleste Lebbé , Grant McArthur , Paolo A Ascierto , Gregory A Daniels , Georgina V Long , Tuba Bas , Corey Ritchings , James Larkin , F Stephen Hodi

Prognostic and predictive value of AJCC-8 staging in the phase III EORTC1325/KEYNOTE-054 trial of pembrolizumab vs placebo in resected high-risk stage III melanoma.

European journal of cancer (Oxford, England : 1990)

Avec: Alexander M M Eggermont , Christian U Blank , Mario Mandala , Georgina V Long , Victoria G Atkinson , Stéphane Dalle , Andrew Haydon , Mikhail Lichinitser , Adnan Khattak , Matteo S Carlino , Shahneen Sandhu , James Larkin , Susana Puig , Paolo A Ascierto , Piotr Rutkowski , Dirk Schadendorf , Rutger Koornstra , Leonel Hernandez-Aya , Anna Maria Di Giacomo , Alfonsus Jm van den Eertwegh , Jean-Jacques Grob , Ralf Gutzmer , Rahima Jamal , Paul C Lorigan , Robert Lupinacci , Clemens Krepler , Nageatte Ibrahim , Michal Kicinski , Sandrine Marreaud , Alexander C van Akkooi , Stefan Suciu , Caroline Robert

Apoptotic Gastritis in Melanoma Patients Treated With PD-1-Based Immune Checkpoint Inhibition - Clinical and Histopathological Findings Including the Diagnostic Value of Anti-Caspase-3 Immunohistochemistry.

Frontiers in oncology

Avec: Jan-Malte Placke , Josefine Rawitzer , Henning Reis , Jassin Rashidi-Alavijeh , Elisabeth Livingstone , Selma Ugurel , Eva Hadaschik , Klaus Griewank , Kurt Werner Schmid , Dirk Schadendorf , Alexander Roesch , Lisa Zimmer

Outcome of melanoma patients with elevated LDH treated with first-line targeted therapy or PD-1-based immune checkpoint inhibition.

European journal of cancer (Oxford, England : 1990)

Avec: Sarah Knispel , Maximilian Gassenmaier , Alexander M Menzies , Carmen Loquai , Douglas B Johnson , Cindy Franklin , Ralf Gutzmer , Jessica C Hassel , Carsten Weishaupt , Thomas Eigentler , Bastian Schilling , Patrick Schummer , Judith Sirokay , Felix Kiecker , Carina N Owen , Maria I Fleischer , Christopher Cann , Katharina C Kähler , Peter Mohr , Leonie Bluhm , Dennis Niebel , Kai-Martin Thoms , Simone M Goldinger , Lydia Reinhardt , Friedegund Meier , Carola Berking , Raphael Reinhard , Laura Susok , Paolo A Ascierto , Konstantin Drexler , Claudia Pföhler , Julia Tietze , Lucie Heinzerling , Elisabeth Livingstone , Selma Ugurel , Georgina V Long , Andreas Stang , Dirk Schadendorf , Lisa Zimmer

Leptomeningeal disease from melanoma-Poor prognosis despite new therapeutic modalities.

European journal of cancer (Oxford, England : 1990)

Avec: Eleftheria Chorti , Sied Kebir , Misbah S Ahmed , Kathy Keyvani , Lale Umutlu , Theodora Kanaki , Anne Zaremba , Finja Reinboldt-Jockenhoefer , Sarah Knispel , Emmanouil Gratsias , Alexander Roesch , Selma Ugurel , Björn Scheffler , Dirk Schadendorf , Elisabeth Livingstone , Friedegund Meier , Martin Glas , Lisa Zimmer

Patterns of care and follow-up care of patients with uveal melanoma in German-speaking countries: a multinational survey of the German Dermatologic Cooperative Oncology Group (DeCOG).

Journal of cancer research and clinical oncology

Avec: Theresa Steeb , Anja Wessely , Mareike Alter , Christiane Bayerl , Armin Bender , Guido Bruning , Evelyn Dabrowski , Dirk Debus , Nina Devereux , Edgar Dippel , Konstantin Drexler , Pia Dücker , Reinhard Dummer , Steffen Emmert , Peter Elsner , Alexander Enk , Christoffer Gebhardt , Anja Gesierich , Matthias Goebeler , Sergij Goerdt , Steven Goetze , Ralf Gutzmer , Sebastian Haferkamp , Gesina Hansel , Jessica C Hassel , Lucie Heinzerling , Katharina C Kähler , Kjell M Kaume , Wolfgang Krapf , Nicole Kreuzberg , Percy Lehmann , Elisabeth Livingstone , Harald Löffler , Carmen Loquai , Cornelia Mauch , Johanna Mangana , Friedegund Meier , Markus Meissner , Rose K C Moritz , Lara Valeska Maul , Verena Müller , Peter Mohr , Alexander Navarini , Ahn Van Nguyen , Christiane Pfeiffer , Claudia Pföhler , Christian Posch , Erika Richtig , Rainer Rompel , Michael M Sachse , Stefanie Sauder , Dirk Schadendorf , Kerstin Schatton , Hans-Joachim Schulze , Erwin Schultz , Bastian Schilling , Matthias Schmuth , Jan C Simon , Markus Streit , Patrick Terheyden , Alexander Thiem , Thomas Tüting , Julia Welzel , Gerhard Weyandt , Ulrich Wesselmann , Uwe Wollina , Mirjana Ziemer , Lisa Zimmer , Markus Zutt , Carola Berking , Max Schlaak , Markus V Heppt , Auteur inconnu

Circulating tumour DNA in patients with advanced melanoma treated with dabrafenib or dabrafenib plus trametinib: a clinical validation study.

The Lancet. Oncology

Avec: Mahrukh M Syeda , Jennifer M Wiggins , Broderick C Corless , Georgina V Long , Keith T Flaherty , Dirk Schadendorf , Paul D Nathan , Caroline Robert , Antoni Ribas , Michael A Davies , Jean Jacques Grob , Eduard Gasal , Matthew Squires , Mahtab Marker , James Garrett , Jan C Brase , David Polsky

Mental Health Burden of German Cancer Patients before and after the Outbreak of COVID-19: Predictors of Mental Health Impairment.

International journal of environmental research and public health

Avec: Alexander Bäuerle , Venja Musche , Kira Schmidt , Adam Schweda , Madeleine Fink , Benjamin Weismüller , Hannah Kohler , Ken Herrmann , Mitra Tewes , Dirk Schadendorf , Eva-Maria Skoda , Martin Teufel

Mutations in the IFNγ-JAK-STAT Pathway Causing Resistance to Immune Checkpoint Inhibitors in Melanoma Increase Sensitivity to Oncolytic Virus Treatment.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Tan-Trieu Nguyen , LeeAnn Ramsay , Mozhdeh Ahanfeshar-Adams , Mathieu Lajoie , Dirk Schadendorf , Tommy Alain , Ian R Watson

Arenavirus Induced CCL5 Expression Causes NK Cell-Mediated Melanoma Regression.

Frontiers in immunology

Avec: Hilal Bhat , Gregor Zaun , Thamer A Hamdan , Judith Lang , Tom Adomati , Rosa Schmitz , Sarah-Kim Friedrich , Michael Bergerhausen , Lamin B Cham , Fanghui Li , Murtaza Ali , Fan Zhou , Vishal Khairnar , Vikas Duhan , Tim Brandenburg , Yara Maria Machlah , Maximilian Schiller , Arshia Berry , Haifeng Xu , Jörg Vollmer , Dieter Häussinger , Beatrice Thier , Aleksandra A Pandyra , Dirk Schadendorf , Annette Paschen , Martin Schuler , Philipp A Lang , Karl S Lang

Genetic characterization of advanced conjunctival melanoma and response to systemic treatment.

European journal of cancer (Oxford, England : 1990)

Avec: Georg C Lodde , Philipp Jansen , Inga Möller , Antje Sucker , Jessica C Hassel , Andrea Forschner , Julia Eckardt , Friedegund Meier , Lydia Reinhardt , Katharina C Kähler , Mirjana Ziemer , Max Schlaak , Farnaz Rahimi , Kerstin Schatton , Frank Meiss , Ralf Gutzmer , Claudia Pföhler , Patrick Terheyden , Bastian Schilling , Michael Sachse , Markus V Heppt , Anca Sindrilaru , Ulrike Leiter , Anne Zaremba , Carl M Thielmann , Selma Ugurel , Lisa Zimmer , Eva Hadaschik , Nikolaos E Bechrakis , Dirk Schadendorf , Henrike Westekemper , Elisabeth Livingstone , Klaus G Griewank , Auteur inconnu

Metabolic imaging with FDG-PET and time to progression in patients discontinuing immune-checkpoint inhibition for metastatic melanoma.

Cancer imaging : the official publication of the International Cancer Imaging Society

Avec: Justin Ferdinandus , Anne Zaremba , Lisa Zimmer , Lale Umutlu , Robert Seifert , Francesco Barbato , Selma Ugurel , Eleftheria Chorti , Viktor Grünwald , Ken Herrmann , Dirk Schadendorf , Wolfgang Peter Fendler , Elisabeth Livingstone

PIVOT-12: a phase III study of adjuvant bempegaldesleukin plus nivolumab in resected stage III/IV melanoma at high risk for recurrence.

Future oncology (London, England)

Avec: Alexander Mm Eggermont , Paolo A Ascierto , Nikhil I Khushalani , Dirk Schadendorf , Genevieve Boland , Jeffrey Weber , Karl D Lewis , Daniel Johnson , Gareth Rivalland , Adnan Khattak , Margarita Majem , Helen Gogas , Georgina V Long , Sue L Currie , David Chien , Mary A Tagliaferri , Matteo S Carlino , Adi Diab

Clinical Models to Define Response and Survival With Anti-PD-1 Antibodies Alone or Combined With Ipilimumab in Metastatic Melanoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Inês Pires da Silva , Tasnia Ahmed , Jennifer L McQuade , Caroline A Nebhan , John J Park , Judith M Versluis , Patricio Serra-Bellver , Yasir Khan , Tim Slattery , Honey K Oberoi , Selma Ugurel , Lauren E Haydu , Rudolf Herbst , Jochen Utikal , Claudia Pföhler , Patrick Terheyden , Michael Weichenthal , Ralf Gutzmer , Peter Mohr , Rajat Rai , Jessica L Smith , Richard A Scolyer , Ana M Arance , Lisa Pickering , James Larkin , Paul Lorigan , Christian U Blank , Dirk Schadendorf , Michael A Davies , Matteo S Carlino , Douglas B Johnson , Georgina V Long , Serigne N Lo , Alexander M Menzies

Impact of radiotherapy and sequencing of systemic therapy on survival outcomes in melanoma patients with previously untreated brain metastasis: a multicenter DeCOG study on 450 patients from the prospective skin cancer registry ADOREG.

Journal for immunotherapy of cancer

Avec: Cindy Franklin , Peter Mohr , Leonie Bluhm , Imke Grimmelmann , Ralf Gutzmer , Friedegund Meier , Marlene Garzarolli , Michael Weichenthal , Claudia Pfoehler , Rudolf Herbst , Patrick Terheyden , Jochen Utikal , Jens Ulrich , Dirk Debus , Sebastian Haferkamp , Martin Kaatz , Andrea Forschner , Ulrike Leiter , Dorothee Nashan , Alexander Kreuter , Michael Sachse , Julia Welzel , Lucie Heinzerling , Frank Meiss , Carsten Weishaupt , Thilo Gambichler , Gerhard Weyandt , Edgar Dippel , Kerstin Schatton , Eren Celik , Maike Trommer , Iris Helfrich , Alexander Roesch , Lisa Zimmer , Elisabeth Livingstone , Dirk Schadendorf , Susanne Horn , Selma Ugurel

Prognostic and predictive value of β-blockers in the EORTC 1325/KEYNOTE-054 phase III trial of pembrolizumab versus placebo in resected high-risk stage III melanoma.

European journal of cancer (Oxford, England : 1990)

Avec: Oliver J Kennedy , Michal Kicinski , Sara Valpione , Sara Gandini , Stefan Suciu , Christian U Blank , Georgina V Long , Victoria G Atkinson , Stéphane Dalle , Andrew M Haydon , Andrey Meshcheryakov , Adnan Khattak , Matteo S Carlino , Shahneen Sandhu , James Larkin , Susana Puig , Paolo A Ascierto , Piotr Rutkowski , Dirk Schadendorf , Rutger Koornstra , Leonel Hernandez-Aya , Anna M Di Giacomo , Alfonsus J M van den Eertwegh , Jean-Jacques Grob , Ralf Gutzmer , Rahima Jamal , Alexander C J van Akkooi , Caroline Robert , Alexander M M Eggermont , Paul Lorigan , Mario Mandala

Role of Tumor-Infiltrating B Cells in Clinical Outcome of Patients with Melanoma Treated With Dabrafenib Plus Trametinib.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Jan C Brase , Robert F H Walter , Alexander Savchenko , Daniel Gusenleitner , James Garrett , Tobias Schimming , Renata Varaljai , Deborah Castelletti , Ju Kim , Naveen Dakappagari , Ken Schultz , Caroline Robert , Georgina V Long , Paul D Nathan , Antoni Ribas , Keith T Flaherty , Boguslawa Karaszewska , Jacob Schachter , Antje Sucker , Kurt W Schmid , Lisa Zimmer , Elisabeth Livingstone , Eduard Gasal , Dirk Schadendorf , Alexander Roesch

Immune Checkpoint Blockade for Metastatic Uveal Melanoma: Patterns of Response and Survival According to the Presence of Hepatic and Extrahepatic Metastasis.

Cancers

Avec: Elias A T Koch , Anne Petzold , Anja Wessely , Edgar Dippel , Anja Gesierich , Ralf Gutzmer , Jessica C Hassel , Sebastian Haferkamp , Bettina Hohberger , Katharina C Kähler , Harald Knorr , Nicole Kreuzberg , Ulrike Leiter , Carmen Loquai , Friedegund Meier , Markus Meissner , Peter Mohr , Claudia Pföhler , Farnaz Rahimi , Dirk Schadendorf , Beatrice Schell , Max Schlaak , Patrick Terheyden , Kai-Martin Thoms , Beatrice Schuler-Thurner , Selma Ugurel , Jens Ulrich , Jochen Utikal , Michael Weichenthal , Fabian Ziller , Carola Berking , Markus V Heppt , On Behalf Of The German Dermatologic Cooperative Oncology Group DeCOG Committee Ocular Melanoma

The concepts of rechallenge and retreatment with immune checkpoint blockade in melanoma patients.

European journal of cancer (Oxford, England : 1990)

Avec: Anne Zaremba , Alexander M M Eggermont , Caroline Robert , Reinhardt Dummer , Selma Ugurel , Elisabeth Livingstone , Paolo A Ascierto , Georgina V Long , Dirk Schadendorf , Lisa Zimmer

Skin cancer classification via convolutional neural networks: systematic review of studies involving human experts.

European journal of cancer (Oxford, England : 1990)

Avec: Sarah Haggenmüller , Roman C Maron , Achim Hekler , Jochen S Utikal , Catarina Barata , Raymond L Barnhill , Helmut Beltraminelli , Carola Berking , Brigid Betz-Stablein , Andreas Blum , Stephan A Braun , Richard Carr , Marc Combalia , Maria-Teresa Fernandez-Figueras , Gerardo Ferrara , Sylvie Fraitag , Lars E French , Frank F Gellrich , Kamran Ghoreschi , Matthias Goebeler , Pascale Guitera , Holger A Haenssle , Sebastian Haferkamp , Lucie Heinzerling , Markus V Heppt , Franz J Hilke , Sarah Hobelsberger , Dieter Krahl , Heinz Kutzner , Aimilios Lallas , Konstantinos Liopyris , Mar Llamas-Velasco , Josep Malvehy , Friedegund Meier , Cornelia S L Müller , Alexander A Navarini , Cristián Navarrete-Dechent , Antonio Perasole , Gabriela Poch , Sebastian Podlipnik , Luis Requena , Veronica M Rotemberg , Andrea Saggini , Omar P Sangueza , Carlos Santonja , Dirk Schadendorf , Bastian Schilling , Max Schlaak , Justin G Schlager , Mildred Sergon , Wiebke Sondermann , H Peter Soyer , Hans Starz , Wilhelm Stolz , Esmeralda Vale , Wolfgang Weyers , Alexander Zink , Eva Krieghoff-Henning , Jakob N Kather , Christof von Kalle , Daniel B Lipka , Stefan Fröhling , Axel Hauschild , Harald Kittler , Titus J Brinker

Guideline-Based Context-Sensitive Decision Modeling for Melanoma Patients.

Studies in health technology and informatics

Avec: Catharina Lena Beckmann , Georg Lodde , Elisabeth Livingstone , Dirk Schadendorf , Britta Böckmann

Cancer care in German centers of excellence during the first 2 years of the COVID-19 pandemic.

Journal of cancer research and clinical oncology

Avec: Volker Arndt , Daniela Doege , Stefan Fröhling , Peter Albers , Hana Algül , Ralf Bargou , Carsten Bokemeyer , Martin Bornhäuser , Christian H Brandts , Peter Brossart , Sara Yvonne Brucker , Tim H Brümmendorf , Hartmut Döhner , Norbert Gattermann , Michael Hallek , Volker Heinemann , Ulrich Keilholz , Thomas Kindler , Cornelia von Levetzow , Florian Lordick , Ulf Peter Neumann , Christoph Peters , Dirk Schadendorf , Stephan Stilgenbauer , Thomas Zander , Daniel Zips , Delia Braun , Thomas Seufferlein , Gerd Nettekoven , Michael Baumann

Spartalizumab or placebo in combination with dabrafenib and trametinib in patients with

Journal for immunotherapy of cancer

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Genetic and methylation profiles distinguish benign, malignant and spitzoid melanocytic tumors.

International journal of cancer

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Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Reinhard Dummer , Keith T Flaherty , Caroline Robert , Ana Arance , Jan Willem B de Groot , Claus Garbe , Helen J Gogas , Ralf Gutzmer , Ivana Krajsová , Gabriella Liszkay , Carmen Loquai , Mario Mandalà , Dirk Schadendorf , Naoya Yamazaki , Alessandra di Pietro , Jean Cantey-Kiser , Michelle Edwards , Paolo A Ascierto

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Avec: Jeffrey S Weber , Dirk Schadendorf , Michele Del Vecchio , James Larkin , Victoria Atkinson , Michael Schenker , Jacopo Pigozzo , Helen Gogas , Stéphane Dalle , Nicolas Meyer , Paolo A Ascierto , Shahneen Sandhu , Thomas Eigentler , Ralf Gutzmer , Jessica C Hassel , Caroline Robert , Matteo S Carlino , Anna Maria Di Giacomo , Marcus O Butler , Eva Muñoz-Couselo , Michael P Brown , Piotr Rutkowski , Andrew Haydon , Jean-Jacques Grob , Jacob Schachter , Paola Queirolo , Luis de la Cruz-Merino , Andre van der Westhuizen , Alexander M Menzies , Sandra Re , Tuba Bas , Veerle de Pril , Julia Braverman , Daniel J Tenney , Hao Tang , Georgina V Long

Réseau de co-auteurs

Elisabeth Livingstone 31 collaborations

Lisa Zimmer 28 collaborations

Ralf Gutzmer 25 collaborations

Georgina V Long 25 collaborations

Selma Ugurel 24 collaborations

Paolo A Ascierto 21 collaborations

Caroline Robert 20 collaborations

Friedegund Meier 18 collaborations

None None 17 collaborations

Sebastian Haferkamp 15 collaborations

Peter Mohr 15 collaborations

Carmen Loquai 14 collaborations

Piotr Rutkowski 14 collaborations

Matteo S Carlino 14 collaborations

Bastian Schilling 13 collaborations

Axel Hauschild 13 collaborations

Reinhard Dummer 12 collaborations

Jean-Jacques Grob 12 collaborations

Carola Berking 12 collaborations

Michael Weichenthal 12 collaborations

Jochen Utikal 11 collaborations

Jessica C Hassel 11 collaborations

Antje Sucker 10 collaborations

Anne Zaremba 10 collaborations

Patrick Terheyden 10 collaborations

James Larkin 10 collaborations

Eva Hadaschik 9 collaborations

Claudia Pföhler 9 collaborations

Christian U Blank 8 collaborations

Annette Paschen 8 collaborations

Alexander Roesch 8 collaborations

Alexander M Menzies 8 collaborations

Edgar Dippel 8 collaborations

Ulrike Leiter 8 collaborations

Victoria Atkinson 7 collaborations

Alexander M M Eggermont 7 collaborations

Ana Arance 7 collaborations

Markus V Heppt 7 collaborations

Jens Ulrich 7 collaborations

Helen Gogas 6 collaborations

Laurent Mortier 6 collaborations

Eleftheria Chorti 6 collaborations

Antoni Ribas 6 collaborations

Eduard Gasal 6 collaborations

Philipp Jansen 6 collaborations

Joachim Klode 6 collaborations

Thomas Eigentler 6 collaborations

Max Schlaak 6 collaborations

F Stephen Hodi 6 collaborations

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Stéphane Dalle 6 collaborations

Katharina C Kähler 6 collaborations

Lucie Heinzerling 6 collaborations

Christoffer Gebhardt 5 collaborations

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Vanna Chiarion-Sileni 5 collaborations

Claus Garbe 5 collaborations

Keith T Flaherty 5 collaborations

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Mario Mandala 5 collaborations

Clemens Krepler 5 collaborations

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Julia Welzel 5 collaborations

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Susanne Horn 5 collaborations

Frank Meiss 5 collaborations

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Paul Lorigan 5 collaborations

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Caroline Dutriaux 4 collaborations

Alexander C J van Akkooi 4 collaborations

Michal Kicinski 4 collaborations

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Marta Nyakas 4 collaborations

D Schadendorf 4 collaborations

Mario Mandalà 4 collaborations

Paul D Nathan 4 collaborations

Hussein A Tawbi 4 collaborations

Jan C Brase 4 collaborations

Christof von Kalle 4 collaborations

Achim Hekler 4 collaborations

Stefan Fröhling 4 collaborations

Marcus O Butler 4 collaborations

Paola Queirolo 4 collaborations

Klaus Griewank 4 collaborations

Georg Lodde 4 collaborations

Alexander Kreuter 4 collaborations

Alexander H Enk 4 collaborations

Cindy Franklin 4 collaborations

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Ken Herrmann 4 collaborations

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Imke Satzger 3 collaborations

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Omid Hamid 3 collaborations

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L Zimmer 3 collaborations

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Daniel Gusenleitner 3 collaborations

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E Livingstone 2 collaborations

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