Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation.


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
02 05 2019
Historique:
received: 04 03 2018
accepted: 28 03 2019
entrez: 4 5 2019
pubmed: 3 5 2019
medline: 14 6 2019
Statut: epublish

Résumé

Mutations in the nucleophosmin 1 (NPM1) gene are considered founder mutations in the pathogenesis of acute myeloid leukemia (AML). To characterize the genetic composition of NPM1 mutated (NPM1

Identifiants

pubmed: 31048683
doi: 10.1038/s41467-019-09745-2
pii: 10.1038/s41467-019-09745-2
pmc: PMC6497712
doi:

Substances chimiques

NPM1 protein, human 0
Nuclear Proteins 0
Nucleophosmin 117896-08-9

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2031

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Auteurs

Sibylle Cocciardi (S)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany.

Anna Dolnik (A)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany.

Silke Kapp-Schwoerer (S)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany.

Frank G Rücker (FG)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany.

Susanne Lux (S)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany.

Tamara J Blätte (TJ)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany.

Sabrina Skambraks (S)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany.

Jan Krönke (J)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany.

Florian H Heidel (FH)

Department of Internal Medicine II, Hematology and Oncology, Friedrich-Schiller-University Medical Center, Jena, 07743, Germany.
Leibniz-Institute on Aging, Fritz-Lipmann-Institute, Jena, 07745, Germany.

Tina M Schnöder (TM)

Department of Internal Medicine II, Hematology and Oncology, Friedrich-Schiller-University Medical Center, Jena, 07743, Germany.
Leibniz-Institute on Aging, Fritz-Lipmann-Institute, Jena, 07745, Germany.

Andrea Corbacioglu (A)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany.

Verena I Gaidzik (VI)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany.

Peter Paschka (P)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany.

Veronica Teleanu (V)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany.

Gudrun Göhring (G)

Institute of Cell & Molecular Pathology, Hannover Medical School, Hannover, 30625, Germany.

Felicitas Thol (F)

Department of Haematology, Haemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, 30625, Germany.

Michael Heuser (M)

Department of Haematology, Haemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, 30625, Germany.

Arnold Ganser (A)

Department of Haematology, Haemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, 30625, Germany.

Daniela Weber (D)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany.

Eric Sträng (E)

Institute of Medical Systems Biology, Ulm University, Ulm, 30625, Germany.

Hans A Kestler (HA)

Institute of Medical Systems Biology, Ulm University, Ulm, 30625, Germany.

Hartmut Döhner (H)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany.

Lars Bullinger (L)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany. lars.bullinger@charite.de.
Department of Hematology, Oncology and Tumorimmunology, Charité University Medicine, Berlin, 13353, Germany. lars.bullinger@charite.de.

Konstanze Döhner (K)

Department of Internal Medicine III, University Hospital of Ulm, Ulm, 89081, Germany. konstanze.doehner@uniklinik-ulm.de.

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Classifications MeSH