Thomas Burgoyne

Affiliations

Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London SW3 6NP, UK.
UCL Institute of Ophthalmology, University College London, London EC1V 9EL, UK.

Publications (26)

UA-Zero as a Uranyl Acetate Replacement When Diagnosing Primary Ciliary Dyskinesia by Transmission Electron Microscopy.

Diagnostics (Basel, Switzerland)

Avec: Andreia Lucia Pinto , Ranjit Kaur Rai , Amelia Shoemark , Claire Hogg , Thomas Burgoyne

SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Miao Gui , Jacob T Croft , Davide Zabeo , Vajradhar Acharya , Justin M Kollman , Thomas Burgoyne , Johanna L Höög , Alan Brown

Tetherin antagonism by SARS-CoV-2 ORF3a and spike protein enhances virus release.

EMBO reports

Avec: Hazel Stewart , Roberta Palmulli , Kristoffer H Johansen , Naomi McGovern , Ola M Shehata , George W Carnell , Hannah K Jackson , Jin S Lee , Jonathan C Brown , Thomas Burgoyne , Jonathan L Heeney , Klaus Okkenhaug , Andrew E Firth , Andrew A Peden , James R Edgar

Ciliary Feature Counter: A program for the Quantitative Assessment of Cilia to Diagnose Primary Ciliary Dyskinesia.

Diagnostics (Basel, Switzerland)

Avec: Andreia L Pinto , Ranjit K Rai , Claire Hogg , Thomas Burgoyne

Selective Ablation of Megalin in the Retinal Pigment Epithelium Results in Megaophthalmos, Macromelanosome Formation and Severe Retina Degeneration.

Investigative ophthalmology & visual science

Avec: Tina Storm , Thomas Burgoyne , Joshua L Dunaief , Erik I Christensen , Clare Futter , Rikke Nielsen

Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity.

Journal of extracellular vesicles

Avec: Silvia Oggero , Monica de Gaetano , Simone Marcone , Stephen Fitzsimons , Andreia L Pinto , Dinara Ikramova , Mary Barry , David Burke , Trinidad Montero-Melendez , Dianne Cooper , Thomas Burgoyne , Orina Belton , Lucy V Norling , Eoin P Brennan , Catherine Godson , Mauro Perretti

PCD Detect: enhancing ciliary features through image averaging and classification.

American journal of physiology. Lung cellular and molecular physiology

Avec: Amelia Shoemark , Andreia L Pinto , Mitali P Patel , Farheen Daudvohra , Claire Hogg , Hannah M Mitchison , Thomas Burgoyne

Ultrastructural insight into SARS-CoV-2 entry and budding in human airway epithelium.

Nature communications

Avec: Andreia L Pinto , Ranjit K Rai , Jonathan C Brown , Paul Griffin , James R Edgar , Anand Shah , Aran Singanayagam , Claire Hogg , Wendy S Barclay , Clare E Futter , Thomas Burgoyne

Changes in Mitochondrial Size and Morphology in the RPE and Photoreceptors of the Developing and Ageing Zebrafish.

Cells

Avec: Thomas Burgoyne , Maria Toms , Chris Way , Dhani Tracey-White , Clare E Futter , Mariya Moosajee

Developmental Expression of the Cell Cycle Regulator p16

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Avec: Cristina Martinez-Fernandez de la Camara , Tina Storm , Ahmed Salman , Thomas Burgoyne , Martin Qvist Rasmussen , Harry O Orlans , Angela J Russell , Stephen G Davies , Alun R Barnard , Robert E MacLaren

Impaired Lysosome Reformation in Chloroquine-Treated Retinal Pigment Epithelial Cells.

Investigative ophthalmology & visual science

Avec: M Helena Cardoso , Michael J Hall , Thomas Burgoyne , Pedro Fale , Tina Storm , Cristina Escrevente , Pedro Antas , Miguel C Seabra , Clare E Futter

Age-specific nasal epithelial responses to SARS-CoV-2 infection.

Nature microbiology

Avec: Maximillian N J Woodall , Ana-Maria Cujba , Kaylee B Worlock , Katie-Marie Case , Tereza Masonou , Masahiro Yoshida , Krzysztof Polanski , Ni Huang , Rik G H Lindeboom , Lira Mamanova , Liam Bolt , Laura Richardson , Batuhan Cakir , Samuel Ellis , Machaela Palor , Thomas Burgoyne , Andreia Pinto , Dale Moulding , Timothy D McHugh , Aarash Saleh , Eliz Kilich , Puja Mehta , Chris O'Callaghan , Jie Zhou , Wendy Barclay , Paolo DeCoppi , Colin R Butler , Mario Cortina-Borja , Heloise Vinette , Sunando Roy , Judith Breuer , Rachel C Chambers , Wendy E Heywood , Kevin Mills , Robert E Hynds , Sarah A Teichmann , Kerstin B Meyer , Marko Z Nikolić , Claire M Smith

Combined approaches, including long-read sequencing, address the diagnostic challenge of HYDIN in primary ciliary dyskinesia.

European journal of human genetics : EJHG

Avec: Andrew Fleming , Miranda Galey , Lizi Briggs , Matthew Edwards , Claire Hogg , Shibu John , Sam Wilkinson , Ellie Quinn , Ranjit Rai , Tom Burgoyne , Andy Rogers , Mitali P Patel , Paul Griffin , Steven Muller , Siobhan B Carr , Michael R Loebinger , Jane S Lucas , Anand Shah , Ricardo Jose , Hannah M Mitchison , Amelia Shoemark , Danny E Miller , Deborah J Morris-Rosendahl

Remodeling of the Basal Labyrinth of Retinal Pigment Epithelial Cells With Osmotic Challenge, Age, and Disease.

Investigative ophthalmology & visual science

Avec: Matthew J Hayes , Thomas Burgoyne , Silene T Wavre-Shapton , Tanya Tolmachova , Miguel C Seabra , Clare E Futter

Physiological and Pathophysiological Aspects of Primary Cilia-A Literature Review with View on Functional and Structural Relationships in Cartilage.

International journal of molecular sciences

Avec: Friedrich Barsch , Tanja Niedermair , Andreas Mamilos , Volker H Schmitt , David Grevenstein , Maximilian Babel , Thomas Burgoyne , Amelia Shoemark , Christoph Brochhausen

Membrane trafficking in the retinal pigment epithelium at a glance.

Journal of cell science

Avec: Tina Storm , Thomas Burgoyne , Clare E Futter

Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells.

PLoS biology

Avec: Teresa Buenaventura , Stavroula Bitsi , William E Laughlin , Thomas Burgoyne , Zekun Lyu , Affiong I Oqua , Hannah Norman , Emma R McGlone , Andrey S Klymchenko , Ivan R Corrêa , Abigail Walker , Asuka Inoue , Aylin Hanyaloglu , Jak Grimes , Zsombor Koszegi , Davide Calebiro , Guy A Rutter , Stephen R Bloom , Ben Jones , Alejandra Tomas

Tetherin antagonism by SARS-CoV-2 enhances virus release: multiple mechanisms including ORF3a-mediated defective retrograde traffic.

bioRxiv : the preprint server for biology

Zebrafish Motile Cilia as a Model for Primary Ciliary Dyskinesia.

International journal of molecular sciences

Avec: Andreia L Pinto , Margarida Rasteiro , Catarina Bota , Sara Pestana , Pedro Sampaio , Claire Hogg , Thomas Burgoyne , Susana S Lopes

Loss of REP1 impacts choroidal melanogenesis and vasculogenesis in choroideremia.

Biochimica et biophysica acta. Molecular basis of disease

Avec: Hajrah Sarkar , Dhani Tracey-White , Ahmed M Hagag , Thomas Burgoyne , Neelima Nair , Lasse D Jensen , Malia M Edwards , Mariya Moosajee

Rescue of cone and rod photoreceptor function in a CDHR1-model of age-related retinal degeneration.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Imran H Yusuf , Thomas Burgoyne , Ahmed Salman , Michelle E McClements , Robert E MacLaren , Peter Charbel Issa

Functional Changes Within the Rod Inner Segment Ellipsoid in Wildtype Mice: An Optical Coherence Tomography and Electron Microscopy Study.

Investigative ophthalmology & visual science

Avec: Bruce A Berkowitz , Robert H Podolsky , Karen Lins Childers , Tom Burgoyne , Giulia De Rossi , Haohua Qian , Robin Roberts , Ryan Katz , Rida Waseem , Cole Goodman

Immunobiology of a rationally-designed AAV2 capsid following intravitreal delivery in mice.

Gene therapy

Avec: Michael Whitehead , Andrew Sage , Tom Burgoyne , Andrew Osborne , Patrick Yu-Wai-Man , Keith R Martin

Disruption of CFAP418 interaction with lipids causes widespread abnormal membrane-associated cellular processes in retinal degenerations.

JCI insight

Avec: Anna M Clark , Dongmei Yu , Grace Neiswanger , Daniel Zhu , Junhuang Zou , J Alan Maschek , Thomas Burgoyne , Jun Yang

Daily Light Onset and Plasma Membrane Tethers Regulate Mitochondria Redistribution within the Retinal Pigment Epithelium.

Cells

Avec: Matilde V Neto , Giulia De Rossi , Bruce A Berkowitz , Miguel C Seabra , Philip J Luthert , Clare E Futter , Thomas Burgoyne

Symmetric arrangement of mitochondria:plasma membrane contacts between adjacent photoreceptor cells regulated by Opa1.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Ingrid P Meschede , Nicholas C Ovenden , Miguel C Seabra , Clare E Futter , Marcela Votruba , Michael E Cheetham , Thomas Burgoyne

Réseau de co-auteurs

Clare E Futter 7 collaborations

Claire Hogg 6 collaborations

Andreia L Pinto 5 collaborations

Amelia Shoemark 4 collaborations

Tina Storm 4 collaborations

Miguel C Seabra 4 collaborations

Jonathan C Brown 3 collaborations

James R Edgar 3 collaborations

Tom Burgoyne 3 collaborations

Hazel Stewart 2 collaborations

Roberta Palmulli 2 collaborations

Kristoffer H Johansen 2 collaborations

Naomi McGovern 2 collaborations

Ola M Shehata 2 collaborations

George W Carnell 2 collaborations

Hannah K Jackson 2 collaborations

Jin S Lee 2 collaborations

Jonathan L Heeney 2 collaborations

Klaus Okkenhaug 2 collaborations

Andrew E Firth 2 collaborations

Andrew A Peden 2 collaborations

Ranjit K Rai 2 collaborations

Mitali P Patel 2 collaborations

Hannah M Mitchison 2 collaborations

Paul Griffin 2 collaborations

Anand Shah 2 collaborations

Dhani Tracey-White 2 collaborations

Mariya Moosajee 2 collaborations

Ahmed Salman 2 collaborations

Robert E MacLaren 2 collaborations

Bruce A Berkowitz 2 collaborations

Giulia De Rossi 2 collaborations

Andreia Lucia Pinto 1 collaboration

Ranjit Kaur Rai 1 collaboration

Miao Gui 1 collaboration

Jacob T Croft 1 collaboration

Davide Zabeo 1 collaboration

Vajradhar Acharya 1 collaboration

Justin M Kollman 1 collaboration

Johanna L Höög 1 collaboration

Alan Brown 1 collaboration

Joshua L Dunaief 1 collaboration

Erik I Christensen 1 collaboration

Clare Futter 1 collaboration

Rikke Nielsen 1 collaboration

Silvia Oggero 1 collaboration

Monica de Gaetano 1 collaboration

Simone Marcone 1 collaboration

Stephen Fitzsimons 1 collaboration

Dinara Ikramova 1 collaboration

Mary Barry 1 collaboration

David Burke 1 collaboration

Trinidad Montero-Melendez 1 collaboration

Dianne Cooper 1 collaboration

Orina Belton 1 collaboration

Lucy V Norling 1 collaboration

Eoin P Brennan 1 collaboration

Catherine Godson 1 collaboration

Mauro Perretti 1 collaboration

Farheen Daudvohra 1 collaboration

Aran Singanayagam 1 collaboration

Wendy S Barclay 1 collaboration

Maria Toms 1 collaboration

Chris Way 1 collaboration

Cristina Martinez-Fernandez de la Camara 1 collaboration

Martin Qvist Rasmussen 1 collaboration

Harry O Orlans 1 collaboration

Angela J Russell 1 collaboration

Stephen G Davies 1 collaboration

Alun R Barnard 1 collaboration

M Helena Cardoso 1 collaboration

Michael J Hall 1 collaboration

Pedro Fale 1 collaboration

Cristina Escrevente 1 collaboration

Pedro Antas 1 collaboration

Maximillian N J Woodall 1 collaboration

Ana-Maria Cujba 1 collaboration

Kaylee B Worlock 1 collaboration

Katie-Marie Case 1 collaboration

Tereza Masonou 1 collaboration

Masahiro Yoshida 1 collaboration

Krzysztof Polanski 1 collaboration

Ni Huang 1 collaboration

Rik G H Lindeboom 1 collaboration

Lira Mamanova 1 collaboration

Liam Bolt 1 collaboration

Laura Richardson 1 collaboration

Batuhan Cakir 1 collaboration

Samuel Ellis 1 collaboration

Machaela Palor 1 collaboration

Andreia Pinto 1 collaboration

Dale Moulding 1 collaboration

Timothy D McHugh 1 collaboration

Aarash Saleh 1 collaboration

Eliz Kilich 1 collaboration

Puja Mehta 1 collaboration

Chris O'Callaghan 1 collaboration

Jie Zhou 1 collaboration

Wendy Barclay 1 collaboration

Paolo DeCoppi 1 collaboration

Colin R Butler 1 collaboration

Mario Cortina-Borja 1 collaboration

Heloise Vinette 1 collaboration

Sunando Roy 1 collaboration

Judith Breuer 1 collaboration

Rachel C Chambers 1 collaboration

Wendy E Heywood 1 collaboration

Kevin Mills 1 collaboration

Robert E Hynds 1 collaboration

Sarah A Teichmann 1 collaboration

Kerstin B Meyer 1 collaboration

Marko Z Nikolić 1 collaboration

Claire M Smith 1 collaboration

Andrew Fleming 1 collaboration

Miranda Galey 1 collaboration

Lizi Briggs 1 collaboration

Matthew Edwards 1 collaboration

Shibu John 1 collaboration

Sam Wilkinson 1 collaboration

Ellie Quinn 1 collaboration

Ranjit Rai 1 collaboration

Andy Rogers 1 collaboration

Steven Muller 1 collaboration

Siobhan B Carr 1 collaboration

Michael R Loebinger 1 collaboration

Jane S Lucas 1 collaboration

Ricardo Jose 1 collaboration

Danny E Miller 1 collaboration

Deborah J Morris-Rosendahl 1 collaboration

Matthew J Hayes 1 collaboration

Silene T Wavre-Shapton 1 collaboration

Tanya Tolmachova 1 collaboration

Friedrich Barsch 1 collaboration

Tanja Niedermair 1 collaboration

Andreas Mamilos 1 collaboration

Volker H Schmitt 1 collaboration

David Grevenstein 1 collaboration

Maximilian Babel 1 collaboration

Christoph Brochhausen 1 collaboration

Teresa Buenaventura 1 collaboration

Stavroula Bitsi 1 collaboration

William E Laughlin 1 collaboration

Zekun Lyu 1 collaboration

Affiong I Oqua 1 collaboration

Hannah Norman 1 collaboration

Emma R McGlone 1 collaboration

Andrey S Klymchenko 1 collaboration

Ivan R Corrêa 1 collaboration

Abigail Walker 1 collaboration

Asuka Inoue 1 collaboration

Aylin Hanyaloglu 1 collaboration

Jak Grimes 1 collaboration

Zsombor Koszegi 1 collaboration

Davide Calebiro 1 collaboration

Guy A Rutter 1 collaboration

Stephen R Bloom 1 collaboration

Ben Jones 1 collaboration

Alejandra Tomas 1 collaboration

Margarida Rasteiro 1 collaboration

Catarina Bota 1 collaboration

Sara Pestana 1 collaboration

Pedro Sampaio 1 collaboration

Susana S Lopes 1 collaboration

Hajrah Sarkar 1 collaboration

Ahmed M Hagag 1 collaboration

Neelima Nair 1 collaboration

Lasse D Jensen 1 collaboration

Malia M Edwards 1 collaboration

Imran H Yusuf 1 collaboration

Michelle E McClements 1 collaboration

Peter Charbel Issa 1 collaboration

Robert H Podolsky 1 collaboration

Karen Lins Childers 1 collaboration

Haohua Qian 1 collaboration

Robin Roberts 1 collaboration

Ryan Katz 1 collaboration

Rida Waseem 1 collaboration

Cole Goodman 1 collaboration

Michael Whitehead 1 collaboration

Andrew Sage 1 collaboration

Andrew Osborne 1 collaboration

Patrick Yu-Wai-Man 1 collaboration

Keith R Martin 1 collaboration

Anna M Clark 1 collaboration

Dongmei Yu 1 collaboration

Grace Neiswanger 1 collaboration

Daniel Zhu 1 collaboration

Junhuang Zou 1 collaboration

J Alan Maschek 1 collaboration

Jun Yang 1 collaboration

Matilde V Neto 1 collaboration

Philip J Luthert 1 collaboration

Ingrid P Meschede 1 collaboration

Nicholas C Ovenden 1 collaboration

Marcela Votruba 1 collaboration

Michael E Cheetham 1 collaboration