Robert E Hynds

Affiliations

Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.

Publications (21)

Expansion of Human Airway Basal Stem Cells and Their Differentiation as 3D Tracheospheres.

Methods in molecular biology (Clifton, N.J.)

Avec: Colin R Butler , Sam M Janes , Adam Giangreco

Stem Cell-derived Respiratory Epithelial Cell Cultures as Human Disease Models.

American journal of respiratory cell and molecular biology

Avec: Jessica C Orr ,

COVID-19: Extensive epithelial damage and ciliary dyskinesia in hospitalised patients.

Rhinology

Avec: D D H Lee , D Cardinale , Y Saman , R A Hirst , N Wilson , V Corden , A Rutman , T de Haro , R E Hynds , T McHugh , P Rea , C M Smith , C Oâ Callaghan

Lentiviral expression of wildtype LAMA3A restores cell adhesion in airway basal cells from children with epidermolysis bullosa.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Chun Hang Lau , Maral J Rouhani , Elizabeth F Maughan , Jessica C Orr , Krishna K Kolluri , David R Pearce , Elizabeth Haughey , Liam Sutton , Sam Flatau , Pablo Lopez Balboa , Maria Laura Bageta , Christopher O'Callaghan , Claire M Smith , Sam M Janes , Richard Hewitt , Gabriela Petrof , Anna E Martinez , John A McGrath , Colin R Butler ,

Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer.

Frontiers in oncology

Avec: David R Pearce , Ayse U Akarca , Roel P H De Maeyer , Emily Kostina , Ariana Huebner , Monica Sivakumar , Takahiro Karasaki , Kavina Shah , Sam M Janes , Nicholas McGranahan , Venkat Reddy , Arne N Akbar , David A Moore , Teresa Marafioti , Charles Swanton ,

Stem Cells, Cell Therapies and Bioengineering in Lung Biology and Diseases 2023.

American journal of physiology. Lung cellular and molecular physiology

Avec: Chelsea M Magin , Laertis Ikonomou , Yael Aschner , Michael F Beers , Janette K Burgess , Rebecca L Heise , Patrick S Hume , Anna D Krasnodembskaya , Shirley H J Mei , Alexander V Misharin , Jin-Ah Park , Susan D Reynolds , Daniel J Tschumperlin , Alicia E Tanneberger , Sriram Vaidyanathan , Christopher M Waters , Patricia J Zettler , Daniel J Weiss , Amy L Ryan

Immune Surveillance in Clinical Regression of Preinvasive Squamous Cell Lung Cancer.

Cancer discovery

Avec: Adam Pennycuick , Vitor H Teixeira , Khalid AbdulJabbar , Shan E Ahmed Raza , Tom Lund , Ayse U Akarca , Rachel Rosenthal , Lukas Kalinke , Deepak P Chandrasekharan , Christodoulos P Pipinikas , Henry Lee-Six , Kate H C Gowers , Jake Y Henry , Fraser R Millar , Yeman B Hagos , Celine Denais , Mary Falzon , David A Moore , Sophia Antoniou , Pascal F Durrenberger , Andrew J Furness , Bernadette Carroll , Claire Marceaux , Marie-Liesse Asselin-Labat , William Larson , Courtney Betts , Lisa M Coussens , Ricky M Thakrar , Jeremy George , Charles Swanton , Christina Thirlwell , Peter J Campbell , Teresa Marafioti , Yinyin Yuan , Sergio A Quezada , Nicholas McGranahan , Sam M Janes

Using a Three-Dimensional Collagen Matrix to Deliver Respiratory Progenitor Cells to Decellularized Trachea In Vivo.

Tissue engineering. Part C, Methods

Avec: Nick J I Hamilton , Kate H C Gowers , Angela Tait , Colin R Butler , Colin Hopper , Alan J Burns , Martin A Birchall , Mark Lowdell , Sam M Janes

Non-Invasive Longitudinal Bioluminescence Imaging of Human Mesoangioblasts in Bioengineered Esophagi.

Tissue engineering. Part C, Methods

Avec: Claire Crowley , Colin R Butler , Carlotta Camilli , Krishna K Kolluri , Sam M Janes , Paolo De Coppi , Luca Urbani

Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories.

Open biology

Avec: Kristopher K Frese , David R Pearce , Eva Grönroos , Caroline Dive , Charles Swanton

Stem cells, cell therapies, and bioengineering in lung biology and disease 2021.

American journal of physiology. Lung cellular and molecular physiology

Avec: Laertis Ikonomou , Mattias Magnusson , Ruben Dries , Erica L Herzog , Zea Borok , Jin-Ah Park , Steven Skolasinski , Janette K Burgess , Leigh Turner , Sarah M Mojarad , John E Mahoney , Thomas Lynch , Mareike Lehmann , Victor J Thannickal , Jamie L Hook , Andrew E Vaughan , Evan T Hoffman , Daniel J Weiss , Amy L Ryan

Modest increase of KIF11 expression exposes fragilities in the mitotic spindle, causing chromosomal instability.

Journal of cell science

Avec: Katie L Dale , Jonathan W Armond , Elina Vladimirou

Lung viral infection modelling in a bioengineered whole-organ.

Biomaterials

Avec: Fabio Tommasini , Thomas Benoist , Soichi Shibuya , Maximillian N J Woodall , Eleonora Naldi , Machaela Palor , Jessica C Orr , Giovanni Giuseppe Giobbe , Elizabeth F Maughan , Tarek Saleh , Asllan Gjinovci , J Ciaran Hutchinson , Owen J Arthurs , Sam M Janes , Nicola Elvassore , Claire M Smith , Federica Michielin , Alessandro Filippo Pellegata , Paolo De Coppi

National Heart, Lung, and Blood Institute and Building Respiratory Epithelium and Tissue for Health (BREATH) Consortium Workshop Report: Moving Forward in Lung Regeneration.

American journal of respiratory cell and molecular biology

Avec: William J Zacharias , Marko Z Nikolić , Melanie Königshoff , Oliver Eickelberg , Reinoud Gosens , Paolo de Coppi , Sam M Janes , Edward Morrisey , Hans Clevers , Amy L Ryan , Barry R Stripp , Xin Sun , Carla F Kim , Qing S Lin

SHOC2 phosphatase-dependent RAF dimerization mediates resistance to MEK inhibition in RAS-mutant cancers.

Nature communications

Avec: Greg G Jones , Isabel Boned Del Río , Sibel Sari , Aysen Sekerim , Lucy C Young , Nicole Hartig , Itziar Areso Zubiaur , Mona A El-Bahrawy , Rob E Hynds , Winnie Lei , Miriam Molina-Arcas , Julian Downward , Pablo Rodriguez-Viciana

The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis.

Nature communications

Avec: Hannah V Woodcock , Jessica D Eley , Delphine Guillotin , Manuela Platé , Carmel B Nanthakumar , Matteo Martufi , Simon Peace , Gerard Joberty , Daniel Poeckel , Robert B Good , Adam R Taylor , Nico Zinn , Matthew Redding , Ellen J Forty , Charles Swanton , Morten Karsdal , Toby M Maher , Andrew Fisher , Giovanna Bergamini , Richard P Marshall , Andy D Blanchard , Paul F Mercer , Rachel C Chambers

Higher throughput drug screening for rare respiratory diseases: readthrough therapy in primary ciliary dyskinesia.

The European respiratory journal

Avec: Dani Do Hyang Lee , Daniela Cardinale , Ersilia Nigro , Colin R Butler , Andrew Rutman , Mahmoud R Fassad , Robert A Hirst , Dale Moulding , Alexander Agrotis , Elisabeth Forsythe , Daniel Peckham , Evie Robson , Claire M Smith , Satyanarayana Somavarapu , Philip L Beales , Stephen L Hart , Sam M Janes , Hannah M Mitchison , Robin Ketteler , Christopher O'Callaghan

Exploiting the potential of lung stem cells to develop pro-regenerative therapies.

Biology open

Avec:

Open questions in human lung organoid research.

Frontiers in pharmacology

Avec: Tessa Hughes , Krijn K Dijkstra , Emma L Rawlins ,

Ciliated Epithelial Cell Differentiation at Air-Liquid Interface Using Commercially Available Culture Media.

Methods in molecular biology (Clifton, N.J.)

Avec: Dani Do Hyang Lee , Alina Petris , Christopher O'Callaghan

Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions.

Nature medicine

Avec: Vitor H Teixeira , Christodoulos P Pipinikas , Adam Pennycuick , Henry Lee-Six , Deepak Chandrasekharan , Jennifer Beane , Tiffany J Morris , Anna Karpathakis , Andrew Feber , Charles E Breeze , Paschalis Ntolios , Mary Falzon , Arrigo Capitanio , Bernadette Carroll , Pascal F Durrenberger , Georgia Hardavella , James M Brown , Andy G Lynch , Henry Farmery , Dirk S Paul , Rachel C Chambers , Nicholas McGranahan , Neal Navani , Ricky M Thakrar , Charles Swanton , Stephan Beck , Phillip Jeremy George , Avrum Spira , Peter J Campbell , Christina Thirlwell , Sam M Janes

Réseau de co-auteurs

Sam M Janes 10 collaborations

Colin R Butler 5 collaborations

Charles Swanton 5 collaborations

Jessica C Orr 3 collaborations

David R Pearce 3 collaborations

Christopher O'Callaghan 3 collaborations

Claire M Smith 3 collaborations

Nicholas McGranahan 3 collaborations

Amy L Ryan 3 collaborations

Elizabeth F Maughan 2 collaborations

Krishna K Kolluri 2 collaborations

Ayse U Akarca 2 collaborations

David A Moore 2 collaborations

Teresa Marafioti 2 collaborations

Laertis Ikonomou 2 collaborations

Janette K Burgess 2 collaborations

Jin-Ah Park 2 collaborations

Daniel J Weiss 2 collaborations

Adam Pennycuick 2 collaborations

Vitor H Teixeira 2 collaborations

Christodoulos P Pipinikas 2 collaborations

Henry Lee-Six 2 collaborations

Kate H C Gowers 2 collaborations

Mary Falzon 2 collaborations

Pascal F Durrenberger 2 collaborations

Bernadette Carroll 2 collaborations

Ricky M Thakrar 2 collaborations

Christina Thirlwell 2 collaborations

Peter J Campbell 2 collaborations

Paolo De Coppi 2 collaborations

Rachel C Chambers 2 collaborations

Dani Do Hyang Lee 2 collaborations

Adam Giangreco 1 collaboration

D D H Lee 1 collaboration

D Cardinale 1 collaboration

Y Saman 1 collaboration

R A Hirst 1 collaboration

N Wilson 1 collaboration

V Corden 1 collaboration

A Rutman 1 collaboration

T de Haro 1 collaboration

R E Hynds 1 collaboration

T McHugh 1 collaboration

P Rea 1 collaboration

C M Smith 1 collaboration

C Oâ Callaghan 1 collaboration

Chun Hang Lau 1 collaboration

Maral J Rouhani 1 collaboration

Elizabeth Haughey 1 collaboration

Liam Sutton 1 collaboration

Sam Flatau 1 collaboration

Pablo Lopez Balboa 1 collaboration

Maria Laura Bageta 1 collaboration

Richard Hewitt 1 collaboration

Gabriela Petrof 1 collaboration

Anna E Martinez 1 collaboration

John A McGrath 1 collaboration

Roel P H De Maeyer 1 collaboration

Emily Kostina 1 collaboration

Ariana Huebner 1 collaboration

Monica Sivakumar 1 collaboration

Takahiro Karasaki 1 collaboration

Kavina Shah 1 collaboration

Venkat Reddy 1 collaboration

Arne N Akbar 1 collaboration

Chelsea M Magin 1 collaboration

Yael Aschner 1 collaboration

Michael F Beers 1 collaboration

Rebecca L Heise 1 collaboration

Patrick S Hume 1 collaboration

Anna D Krasnodembskaya 1 collaboration

Shirley H J Mei 1 collaboration

Alexander V Misharin 1 collaboration

Susan D Reynolds 1 collaboration

Daniel J Tschumperlin 1 collaboration

Alicia E Tanneberger 1 collaboration

Sriram Vaidyanathan 1 collaboration

Christopher M Waters 1 collaboration

Patricia J Zettler 1 collaboration

Khalid AbdulJabbar 1 collaboration

Shan E Ahmed Raza 1 collaboration

Tom Lund 1 collaboration

Rachel Rosenthal 1 collaboration

Lukas Kalinke 1 collaboration

Deepak P Chandrasekharan 1 collaboration

Jake Y Henry 1 collaboration

Fraser R Millar 1 collaboration

Yeman B Hagos 1 collaboration

Celine Denais 1 collaboration

Sophia Antoniou 1 collaboration

Andrew J Furness 1 collaboration

Claire Marceaux 1 collaboration

Marie-Liesse Asselin-Labat 1 collaboration

William Larson 1 collaboration

Courtney Betts 1 collaboration

Lisa M Coussens 1 collaboration

Jeremy George 1 collaboration

Yinyin Yuan 1 collaboration

Sergio A Quezada 1 collaboration

Nick J I Hamilton 1 collaboration

Angela Tait 1 collaboration

Colin Hopper 1 collaboration

Alan J Burns 1 collaboration

Martin A Birchall 1 collaboration

Mark Lowdell 1 collaboration

Claire Crowley 1 collaboration

Carlotta Camilli 1 collaboration

Luca Urbani 1 collaboration

Kristopher K Frese 1 collaboration

Eva Grönroos 1 collaboration

Caroline Dive 1 collaboration

Mattias Magnusson 1 collaboration

Ruben Dries 1 collaboration

Erica L Herzog 1 collaboration

Zea Borok 1 collaboration

Steven Skolasinski 1 collaboration

Leigh Turner 1 collaboration

Sarah M Mojarad 1 collaboration

John E Mahoney 1 collaboration

Thomas Lynch 1 collaboration

Mareike Lehmann 1 collaboration

Victor J Thannickal 1 collaboration

Jamie L Hook 1 collaboration

Andrew E Vaughan 1 collaboration

Evan T Hoffman 1 collaboration

Katie L Dale 1 collaboration

Jonathan W Armond 1 collaboration

Elina Vladimirou 1 collaboration

Fabio Tommasini 1 collaboration

Thomas Benoist 1 collaboration

Soichi Shibuya 1 collaboration

Maximillian N J Woodall 1 collaboration

Eleonora Naldi 1 collaboration

Machaela Palor 1 collaboration

Giovanni Giuseppe Giobbe 1 collaboration

Tarek Saleh 1 collaboration

Asllan Gjinovci 1 collaboration

J Ciaran Hutchinson 1 collaboration

Owen J Arthurs 1 collaboration

Nicola Elvassore 1 collaboration

Federica Michielin 1 collaboration

Alessandro Filippo Pellegata 1 collaboration

William J Zacharias 1 collaboration

Marko Z Nikolić 1 collaboration

Melanie Königshoff 1 collaboration

Oliver Eickelberg 1 collaboration

Reinoud Gosens 1 collaboration

Paolo de Coppi 1 collaboration

Edward Morrisey 1 collaboration

Hans Clevers 1 collaboration

Barry R Stripp 1 collaboration

Xin Sun 1 collaboration

Carla F Kim 1 collaboration

Qing S Lin 1 collaboration

Greg G Jones 1 collaboration

Isabel Boned Del Río 1 collaboration

Sibel Sari 1 collaboration

Aysen Sekerim 1 collaboration

Lucy C Young 1 collaboration

Nicole Hartig 1 collaboration

Itziar Areso Zubiaur 1 collaboration

Mona A El-Bahrawy 1 collaboration

Rob E Hynds 1 collaboration

Winnie Lei 1 collaboration

Miriam Molina-Arcas 1 collaboration

Julian Downward 1 collaboration

Pablo Rodriguez-Viciana 1 collaboration

Hannah V Woodcock 1 collaboration

Jessica D Eley 1 collaboration

Delphine Guillotin 1 collaboration

Manuela Platé 1 collaboration

Carmel B Nanthakumar 1 collaboration

Matteo Martufi 1 collaboration

Simon Peace 1 collaboration

Gerard Joberty 1 collaboration

Daniel Poeckel 1 collaboration

Robert B Good 1 collaboration

Adam R Taylor 1 collaboration

Nico Zinn 1 collaboration

Matthew Redding 1 collaboration

Ellen J Forty 1 collaboration

Morten Karsdal 1 collaboration

Toby M Maher 1 collaboration

Andrew Fisher 1 collaboration

Giovanna Bergamini 1 collaboration

Richard P Marshall 1 collaboration

Andy D Blanchard 1 collaboration

Paul F Mercer 1 collaboration

Daniela Cardinale 1 collaboration

Ersilia Nigro 1 collaboration

Andrew Rutman 1 collaboration

Mahmoud R Fassad 1 collaboration

Robert A Hirst 1 collaboration

Dale Moulding 1 collaboration

Alexander Agrotis 1 collaboration

Elisabeth Forsythe 1 collaboration

Daniel Peckham 1 collaboration

Evie Robson 1 collaboration

Satyanarayana Somavarapu 1 collaboration

Philip L Beales 1 collaboration

Stephen L Hart 1 collaboration

Hannah M Mitchison 1 collaboration

Robin Ketteler 1 collaboration

Tessa Hughes 1 collaboration

Krijn K Dijkstra 1 collaboration

Emma L Rawlins 1 collaboration

Alina Petris 1 collaboration

Deepak Chandrasekharan 1 collaboration

Jennifer Beane 1 collaboration

Tiffany J Morris 1 collaboration

Anna Karpathakis 1 collaboration

Andrew Feber 1 collaboration

Charles E Breeze 1 collaboration

Paschalis Ntolios 1 collaboration

Arrigo Capitanio 1 collaboration

Georgia Hardavella 1 collaboration

James M Brown 1 collaboration

Andy G Lynch 1 collaboration

Henry Farmery 1 collaboration

Dirk S Paul 1 collaboration

Neal Navani 1 collaboration

Stephan Beck 1 collaboration

Phillip Jeremy George 1 collaboration

Avrum Spira 1 collaboration