Michelle E McClements

Affiliations

1 Nuffield Laboratory of Ophthalmology, Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.

Publications (11)

A Quantitative Chloride Channel Conductance Assay for Efficacy Testing of AAV.BEST1.

Human gene therapy methods

Avec: Shaun R Wood , Cristina Martinez-Fernandez de la Camara , Maria I Patrício , Carolina Uggenti , Sumathi Sekaran , Alun R Barnard , Forbes D Manson , Robert E MacLaren

AAV2/8 Anti-angiogenic Gene Therapy Using Single-Chain Antibodies Inhibits Murine Choroidal Neovascularization.

Molecular therapy. Methods & clinical development

Avec: Chris P Hughes , Neil M J O'Flynn , Maureen Gatherer , Jennifer A Scott , Robert E MacLaren , Srinivas Goverdhan , Martin J Glennie , Andrew J Lotery

The Location of Exon 4 Mutations in RP1 Raises Challenges for Genetic Counseling and Gene Therapy.

American journal of ophthalmology

Avec: Anika Nanda , Penny Clouston , Morag E Shanks , Robert E MacLaren

Effect of AAV-Mediated Rhodopsin Gene Augmentation on Retinal Degeneration Caused by the Dominant P23H Rhodopsin Mutation in a Knock-In Murine Model.

Human gene therapy

Avec: Harry O Orlans , Alun R Barnard , Maria I Patrício , Robert E MacLaren

Repair of Retinal Degeneration following Ex Vivo Minicircle DNA Gene Therapy and Transplantation of Corrected Photoreceptor Progenitors.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Alona O Barnea-Cramer , Mandeep Singh , Dominik Fischer , Samantha De Silva , Alun R Barnard , Robert E MacLaren

Characterizing the cellular immune response to subretinal AAV gene therapy in the murine retina.

Molecular therapy. Methods & clinical development

Avec: Laurel C Chandler , Imran H Yusuf , Cristina Martinez-Fernandez de la Camara , Robert E MacLaren , Kanmin Xue

Functional expression of complement factor I following AAV-mediated gene delivery in the retina of mice and human cells.

Gene therapy

Avec: Anna K Dreismann , Alun R Barnard , Elise Orhan , Jane P Hughes , Peter J Lachmann , Robert E MacLaren

Insights on the Regeneration Potential of Müller Glia in the Mammalian Retina.

Cells

Avec: Ahmed Salman , Robert E MacLaren

AAV Induced Expression of Human Rod and Cone Opsin in Bipolar Cells of a Mouse Model of Retinal Degeneration.

BioMed research international

Avec: Federica Staurenghi , Meike Visel , John G Flannery , Robert E MacLaren , Jasmina Cehajic-Kapetanovic

Rescue of cone and rod photoreceptor function in a CDHR1-model of age-related retinal degeneration.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Imran H Yusuf , Thomas Burgoyne , Ahmed Salman , Robert E MacLaren , Peter Charbel Issa

CRISPR DNA Base Editing Strategies for Treating Retinitis Pigmentosa Caused by Mutations in

Genes

Avec: Maria Kaukonen , Robert E MacLaren

Réseau de co-auteurs

Robert E MacLaren 11 collaborations

Alun R Barnard 4 collaborations

Cristina Martinez-Fernandez de la Camara 2 collaborations

Maria I Patrício 2 collaborations

Imran H Yusuf 2 collaborations

Ahmed Salman 2 collaborations

Shaun R Wood 1 collaboration

Carolina Uggenti 1 collaboration

Sumathi Sekaran 1 collaboration

Forbes D Manson 1 collaboration

Chris P Hughes 1 collaboration

Neil M J O'Flynn 1 collaboration

Maureen Gatherer 1 collaboration

Jennifer A Scott 1 collaboration

Srinivas Goverdhan 1 collaboration

Martin J Glennie 1 collaboration

Andrew J Lotery 1 collaboration

Anika Nanda 1 collaboration

Penny Clouston 1 collaboration

Morag E Shanks 1 collaboration

Harry O Orlans 1 collaboration

Alona O Barnea-Cramer 1 collaboration

Mandeep Singh 1 collaboration

Dominik Fischer 1 collaboration

Samantha De Silva 1 collaboration

Laurel C Chandler 1 collaboration

Kanmin Xue 1 collaboration

Anna K Dreismann 1 collaboration

Elise Orhan 1 collaboration

Jane P Hughes 1 collaboration

Peter J Lachmann 1 collaboration

Federica Staurenghi 1 collaboration

Meike Visel 1 collaboration

John G Flannery 1 collaboration

Jasmina Cehajic-Kapetanovic 1 collaboration

Thomas Burgoyne 1 collaboration

Peter Charbel Issa 1 collaboration

Maria Kaukonen 1 collaboration