Shigeki Higashiyama

Affiliations

Division of Cell Growth and Tumor Regulation, PROS, 3 Bunkyo-cho, Matsuyama, Ehime 790-8577.
Department of Biochemistry and Molecular Genetics, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan.

Publications (12)

The E3 ubiquitin ligase MIB2 enhances inflammation by degrading the deubiquitinating enzyme CYLD.

The Journal of biological chemistry

Avec: Atsushi Uematsu , Kohki Kido , Hirotaka Takahashi , Chikako Takahashi , Yuta Yanagihara , Noritaka Saeki , Shuhei Yoshida , Masashi Maekawa , Mamoru Honda , Tsutomu Kai , Kouhei Shimizu , Shigeki Higashiyama , Yuuki Imai , Fuminori Tokunaga , Tatsuya Sawasaki

KCTD10 Biology: An Adaptor for the Ubiquitin E3 Complex Meets Multiple Substrates: Emerging Divergent Roles of the cullin-3/KCTD10 E3 Ubiquitin Ligase Complex in Various Cell Lines.

BioEssays : news and reviews in molecular, cellular and developmental biology

Avec: Masashi Maekawa , Shigeki Higashiyama

Automated measurement of bone scan index from a whole-body bone scintigram.

International journal of computer assisted radiology and surgery

Avec: Akinobu Shimizu , Hayato Wakabayashi , Takumi Kanamori , Atsushi Saito , Kazuhiro Nishikawa , Hiromitsu Daisaki , Shigeaki Higashiyama , Joji Kawabe

Roles of Pyk2 in signal transduction after gonadotropin-releasing hormone receptor stimulation.

Journal of cellular physiology

Avec: Shiho Okitsu-Sakurayama , Sayomi Higa-Nakamine , Hidetsugu Torihara , Shigeki Higashiyama , Hideyuki Yamamoto

CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP.

Life science alliance

Avec: Kanako Nishiyama , Masashi Maekawa , Tomoya Nakagita , Jun Nakayama , Takeshi Kiyoi , Mami Chosei , Akari Murakami , Yoshiaki Kamei , Hiroyuki Takeda , Yasutsugu Takada , Shigeki Higashiyama

Highly concentrated trehalose induces prohealing senescence-like state in fibroblasts via CDKN1A/p21.

Communications biology

Avec: Jun Muto , Shinji Fukuda , Kenji Watanabe , Xiuju Dai , Teruko Tsuda , Takeshi Kiyoi , Kenji Kameda , Ryosuke Kawakami , Hideki Mori , Ken Shiraishi , Masamoto Murakami , Takeshi Imamura , Shigeki Higashiyama , Yasuhiro Fujisawa , Yoichi Mizukami , Koji Sayama

SPOP is essential for DNA replication licensing through maintaining translation of CDT1 and CDC6 in HaCaT cells.

Biochemical and biophysical research communications

Avec: Sayoko Sanada , Masashi Maekawa , Sota Tate , Hiroki Nakaoka , Yasuhiro Fujisawa , Koji Sayama , Shigeki Higashiyama

Schlafen 11 further sensitizes BRCA-deficient cells to PARP inhibitors through single-strand DNA gap accumulation behind replication forks.

Oncogene

Avec: Hiroshi Onji , Sota Tate , Tomohisa Sakaue , Kohei Fujiwara , Shiho Nakano , Miho Kawaida , Nobuyuki Onishi , Takashi Matsumoto , Wataru Yamagami , Takashi Sugiyama , Shigeki Higashiyama , Yves Pommier , Yusuke Kobayashi , Junko Murai

Cullin-3/KCTD10 complex is essential for K27-polyubiquitination of EIF3D in human hepatocellular carcinoma HepG2 cells.

Biochemical and biophysical research communications

Avec: Masashi Maekawa , Hiromi Hiyoshi , Jun Nakayama , Kohki Kido , Tatsuya Sawasaki , Kentaro Semba , Eiji Kubota , Takashi Joh , Shigeki Higashiyama

Cullin-3/KCTD10 E3 complex is essential for Rac1 activation through RhoB degradation in human epidermal growth factor receptor 2-positive breast cancer cells.

Cancer science

Avec: Akari Murakami , Masashi Maekawa , Katsuhisa Kawai , Jun Nakayama , Nobukazu Araki , Kentaro Semba , Tomohiko Taguchi , Yoshiaki Kamei , Yasutsugu Takada , Shigeki Higashiyama

Prognostic significance of pretreatment 18F-fluorodeoxyglucose positron emission tomography evaluation using metabolic tumor volume of the primary tumor and lymph nodes in advanced hypopharyngeal cancer.

Head & neck

Avec: Eiichiro Okazaki , Joji Kawabe , Masahiro Oishi , Masako Hosono , Shigeaki Higashiyama , Yuichi Teranishi , Susumu Shiomi , Hiroyoshi Iguchi , Yukio Miki

Study of the Usefulness of Bone Scan Index Calculated From 99m-Technetium- Hydroxymethylene Diphosphonate (

Current medical imaging

Avec: Shigeaki Higashiyama , Atsushi Yoshida , Joji Kawabe

Réseau de co-auteurs

Masashi Maekawa 6 collaborations

Shigeaki Higashiyama 3 collaborations

Joji Kawabe 3 collaborations

Jun Nakayama 3 collaborations

Kohki Kido 2 collaborations

Tatsuya Sawasaki 2 collaborations

Takeshi Kiyoi 2 collaborations

Akari Murakami 2 collaborations

Yoshiaki Kamei 2 collaborations

Yasutsugu Takada 2 collaborations

Yasuhiro Fujisawa 2 collaborations

Koji Sayama 2 collaborations

Sota Tate 2 collaborations

Kentaro Semba 2 collaborations

Atsushi Uematsu 1 collaboration

Hirotaka Takahashi 1 collaboration

Chikako Takahashi 1 collaboration

Yuta Yanagihara 1 collaboration

Noritaka Saeki 1 collaboration

Shuhei Yoshida 1 collaboration

Mamoru Honda 1 collaboration

Tsutomu Kai 1 collaboration

Kouhei Shimizu 1 collaboration

Yuuki Imai 1 collaboration

Fuminori Tokunaga 1 collaboration

Akinobu Shimizu 1 collaboration

Hayato Wakabayashi 1 collaboration

Takumi Kanamori 1 collaboration

Atsushi Saito 1 collaboration

Kazuhiro Nishikawa 1 collaboration

Hiromitsu Daisaki 1 collaboration

Shiho Okitsu-Sakurayama 1 collaboration

Sayomi Higa-Nakamine 1 collaboration

Hidetsugu Torihara 1 collaboration

Hideyuki Yamamoto 1 collaboration

Kanako Nishiyama 1 collaboration

Tomoya Nakagita 1 collaboration

Mami Chosei 1 collaboration

Hiroyuki Takeda 1 collaboration

Jun Muto 1 collaboration

Shinji Fukuda 1 collaboration

Kenji Watanabe 1 collaboration

Xiuju Dai 1 collaboration

Teruko Tsuda 1 collaboration

Kenji Kameda 1 collaboration

Ryosuke Kawakami 1 collaboration

Hideki Mori 1 collaboration

Ken Shiraishi 1 collaboration

Masamoto Murakami 1 collaboration

Takeshi Imamura 1 collaboration

Yoichi Mizukami 1 collaboration

Sayoko Sanada 1 collaboration

Hiroki Nakaoka 1 collaboration

Hiroshi Onji 1 collaboration

Tomohisa Sakaue 1 collaboration

Kohei Fujiwara 1 collaboration

Shiho Nakano 1 collaboration

Miho Kawaida 1 collaboration

Nobuyuki Onishi 1 collaboration

Takashi Matsumoto 1 collaboration

Wataru Yamagami 1 collaboration

Takashi Sugiyama 1 collaboration

Yves Pommier 1 collaboration

Yusuke Kobayashi 1 collaboration

Junko Murai 1 collaboration

Hiromi Hiyoshi 1 collaboration

Eiji Kubota 1 collaboration

Takashi Joh 1 collaboration

Katsuhisa Kawai 1 collaboration

Nobukazu Araki 1 collaboration

Tomohiko Taguchi 1 collaboration

Eiichiro Okazaki 1 collaboration

Masahiro Oishi 1 collaboration

Masako Hosono 1 collaboration

Yuichi Teranishi 1 collaboration

Susumu Shiomi 1 collaboration

Hiroyoshi Iguchi 1 collaboration

Yukio Miki 1 collaboration

Atsushi Yoshida 1 collaboration