Tomoya Nakagita

Affiliations

Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.
Proteo-Science Center, Ehime University, Ehime 791-8577, Japan.

Publications (16)

Asymmetric Synthesis of Photophore-Containing Lactisole Derivatives to Elucidate Sweet Taste Receptors.

Molecules (Basel, Switzerland)

Avec: Akiko Ishida , Zetryana Puteri Tachrim , Lei Wang , Takumi Misaka , Makoto Hashimoto

A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins.

Biochemical pharmacology

Avec: Ryosuke Segawa , Hiroyuki Takeda , Takeshi Yokoyama , Momoha Ishida , Chihiro Miyata , Taiji Saito , Ryosuke Ishihara , Yusuke Sasano , Naoki Kanoh , Yoshiharu Iwabuchi , Mineyuki Mizuguchi , Masahiro Hiratsuka , Noriyasu Hirasawa

Ligand binding to human prostaglandin E receptor EP

Nature chemical biology

Avec: Yosuke Toyoda , Kazushi Morimoto , Ryoji Suno , Shoichiro Horita , Keitaro Yamashita , Kunio Hirata , Yusuke Sekiguchi , Satoshi Yasuda , Mitsunori Shiroishi , Tomoko Shimizu , Yuji Urushibata , Yuta Kajiwara , Tomoaki Inazumi , Yunhon Hotta , Hidetsugu Asada , Takanori Nakane , Yuki Shiimura , Kyoshiro Tsuge , Suguru Yoshida , Tomoko Kuribara , Takamitsu Hosoya , Yukihiko Sugimoto , Norimichi Nomura , Miwa Sato , Takatsugu Hirokawa , Masahiro Kinoshita , Takeshi Murata , Kiyoshi Takayama , Masaki Yamamoto , Shuh Narumiya , So Iwata , Takuya Kobayashi

Ibuprofen, a Nonsteroidal Anti-Inflammatory Drug, is a Potent Inhibitor of the Human Sweet Taste Receptor.

Chemical senses

Avec: Chiaki Taketani , Masataka Narukawa , Takatsugu Hirokawa , Takuya Kobayashi , Takumi Misaka

A single residue confers selective loss of sugar sensing in wrynecks.

Current biology : CB

Avec: Julia F Cramer , Eliot T Miller , Meng-Ching Ko , Qiaoyi Liang , Glenn Cockburn , Massimiliano Cardinale , Leonida Fusani , Yasuka Toda , Maude W Baldwin

Evolution of the primate glutamate taste sensor from a nucleotide sensor.

Current biology : CB

Avec: Yasuka Toda , Takashi Hayakawa , Akihiro Itoigawa , Yosuke Kurihara , Masahiro Hayashi , Ryuichi Ashino , Amanda D Melin , Yoshiro Ishimaru , Shoji Kawamura , Hiroo Imai , Takumi Misaka

Evaluation of Cell-Free Synthesized Human Channel Proteins for In Vitro Channel Research.

Membranes

Avec: Rei Nishiguchi , Toyohisa Tanaka , Jun Hayashida , Wei Zhou , Hiroyuki Takeda

Structural insights into the differences among lactisole derivatives in inhibitory mechanisms against the human sweet taste receptor.

PloS one

Avec: Akiko Ishida , Takumi Matsuya , Takuya Kobayashi , Masataka Narukawa , Takatsugu Hirokawa , Makoto Hashimoto , Takumi Misaka

CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP.

Life science alliance

Avec: Kanako Nishiyama , Masashi Maekawa , Jun Nakayama , Takeshi Kiyoi , Mami Chosei , Akari Murakami , Yoshiaki Kamei , Hiroyuki Takeda , Yasutsugu Takada , Shigeki Higashiyama

Early origin of sweet perception in the songbird radiation.

Science (New York, N.Y.)

Avec: Yasuka Toda , Meng-Ching Ko , Qiaoyi Liang , Eliot T Miller , Alejandro Rico-Guevara , Ayano Sakakibara , Kana Uemura , Timothy Sackton , Takashi Hayakawa , Simon Yung Wa Sin , Yoshiro Ishimaru , Takumi Misaka , Pablo Oteiza , James Crall , Scott V Edwards , William Buttemer , Shuichi Matsumura , Maude W Baldwin

Recent progress in the use of diaziridine-based sweetener derivatives to elucidate the chemoreception mechanism of the sweet taste receptor.

RSC advances

Avec: Makoto Hashimoto , Takumi Misaka

Synergism, Bifunctionality, and the Evolution of a Gradual Sensory Trade-off in Hummingbird Taste Receptors.

Molecular biology and evolution

Avec: Glenn Cockburn , Meng-Ching Ko , Keren R Sadanandan , Eliot T Miller , Amanda Monte , Sungbo Cho , Eugeni Roura , Yasuka Toda , Maude W Baldwin

A comprehensive interaction study provides a potential domain interaction network of human death domain superfamily proteins.

Cell death and differentiation

Avec: Wei Zhou , Naoe Kaneko , Hiroyuki Takeda , Junya Masumoto

Ibuprofen inhibits oral NaCl response through transmembrane channel-like 4.

Biochemical and biophysical research communications

Avec: Yoichi Kasahara , Masataka Narukawa , Keiko Abe , Takumi Misaka , Tomiko Asakura

Vibrational analysis of acetylcholine binding to the M

RSC advances

Avec: Kohei Suzuki , Kota Katayama , Yuji Sumii , Ryoji Suno , Hirokazu Tsujimoto , So Iwata , Takuya Kobayashi , Norio Shibata , Hideki Kandori

Modeling the structure of the transmembrane domain of T1R3, a subunit of the sweet taste receptor, with neohesperidin dihydrochalcone using molecular dynamics simulation.

Bioscience, biotechnology, and biochemistry

Avec: Takumi Matsuya , Masataka Narukawa , Takuya Kobayashi , Takatsugu Hirokawa , Takumi Misaka

Réseau de co-auteurs

Takumi Misaka 8 collaborations

Takuya Kobayashi 5 collaborations

Hiroyuki Takeda 4 collaborations

Takatsugu Hirokawa 4 collaborations

Masataka Narukawa 4 collaborations

Yasuka Toda 4 collaborations

Makoto Hashimoto 3 collaborations

Eliot T Miller 3 collaborations

Meng-Ching Ko 3 collaborations

Maude W Baldwin 3 collaborations

Akiko Ishida 2 collaborations

Ryoji Suno 2 collaborations

So Iwata 2 collaborations

Qiaoyi Liang 2 collaborations

Glenn Cockburn 2 collaborations

Takashi Hayakawa 2 collaborations

Yoshiro Ishimaru 2 collaborations

Wei Zhou 2 collaborations

Takumi Matsuya 2 collaborations

Zetryana Puteri Tachrim 1 collaboration

Lei Wang 1 collaboration

Ryosuke Segawa 1 collaboration

Takeshi Yokoyama 1 collaboration

Momoha Ishida 1 collaboration

Chihiro Miyata 1 collaboration

Taiji Saito 1 collaboration

Ryosuke Ishihara 1 collaboration

Yusuke Sasano 1 collaboration

Naoki Kanoh 1 collaboration

Yoshiharu Iwabuchi 1 collaboration

Mineyuki Mizuguchi 1 collaboration

Masahiro Hiratsuka 1 collaboration

Noriyasu Hirasawa 1 collaboration

Yosuke Toyoda 1 collaboration

Kazushi Morimoto 1 collaboration

Shoichiro Horita 1 collaboration

Keitaro Yamashita 1 collaboration

Kunio Hirata 1 collaboration

Yusuke Sekiguchi 1 collaboration

Satoshi Yasuda 1 collaboration

Mitsunori Shiroishi 1 collaboration

Tomoko Shimizu 1 collaboration

Yuji Urushibata 1 collaboration

Yuta Kajiwara 1 collaboration

Tomoaki Inazumi 1 collaboration

Yunhon Hotta 1 collaboration

Hidetsugu Asada 1 collaboration

Takanori Nakane 1 collaboration

Yuki Shiimura 1 collaboration

Kyoshiro Tsuge 1 collaboration

Suguru Yoshida 1 collaboration

Tomoko Kuribara 1 collaboration

Takamitsu Hosoya 1 collaboration

Yukihiko Sugimoto 1 collaboration

Norimichi Nomura 1 collaboration

Miwa Sato 1 collaboration

Masahiro Kinoshita 1 collaboration

Takeshi Murata 1 collaboration

Kiyoshi Takayama 1 collaboration

Masaki Yamamoto 1 collaboration

Shuh Narumiya 1 collaboration

Chiaki Taketani 1 collaboration

Julia F Cramer 1 collaboration

Massimiliano Cardinale 1 collaboration

Leonida Fusani 1 collaboration

Akihiro Itoigawa 1 collaboration

Yosuke Kurihara 1 collaboration

Masahiro Hayashi 1 collaboration

Ryuichi Ashino 1 collaboration

Amanda D Melin 1 collaboration

Shoji Kawamura 1 collaboration

Hiroo Imai 1 collaboration

Rei Nishiguchi 1 collaboration

Toyohisa Tanaka 1 collaboration

Jun Hayashida 1 collaboration

Kanako Nishiyama 1 collaboration

Masashi Maekawa 1 collaboration

Jun Nakayama 1 collaboration

Takeshi Kiyoi 1 collaboration

Mami Chosei 1 collaboration

Akari Murakami 1 collaboration

Yoshiaki Kamei 1 collaboration

Yasutsugu Takada 1 collaboration

Shigeki Higashiyama 1 collaboration

Alejandro Rico-Guevara 1 collaboration

Ayano Sakakibara 1 collaboration

Kana Uemura 1 collaboration

Timothy Sackton 1 collaboration

Simon Yung Wa Sin 1 collaboration

Pablo Oteiza 1 collaboration

James Crall 1 collaboration

Scott V Edwards 1 collaboration

William Buttemer 1 collaboration

Shuichi Matsumura 1 collaboration

Keren R Sadanandan 1 collaboration

Amanda Monte 1 collaboration

Sungbo Cho 1 collaboration

Eugeni Roura 1 collaboration

Naoe Kaneko 1 collaboration

Junya Masumoto 1 collaboration

Yoichi Kasahara 1 collaboration

Keiko Abe 1 collaboration

Tomiko Asakura 1 collaboration

Kohei Suzuki 1 collaboration

Kota Katayama 1 collaboration

Yuji Sumii 1 collaboration

Hirokazu Tsujimoto 1 collaboration

Norio Shibata 1 collaboration

Hideki Kandori 1 collaboration