Navlot S Pabla

Publications (15)

Ribociclib mitigates cisplatin-associated kidney injury through retinoblastoma-1 dependent mechanisms.

Biochemical pharmacology

Avec: Ji Young Kim , Laura A Jayne , Yuntao Bai , Mei Ji He Ho Feng , Matthew A Clark , Sangwoon Chung , John W Christman , Rachel E Cianciolo , Navjot Singh Pabla

A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective.

bioRxiv : the preprint server for biology

Avec: Han Wee Ong , Yi Liang , William Richardson , Emily R Lowry , Carrow I Wells , Xiangrong Chen , Margaux Silvestre , Kelvin Dempster , Josie A Silvaroli , Jeffery L Smith , Hynek Wichterle , Navjot S Pabla , Sila K Ultanir , Alex N Bullock , David H Drewry , Alison D Axtman

SOX9 promotes stress-responsive transcription of VGF nerve growth factor inducible gene in renal tubular epithelial cells.

The Journal of biological chemistry

Avec: Ji Young Kim , Yuntao Bai , Laura A Jayne , Ferdos Abdulkader , Megha Gandhi , Tayla Perreau , Samir V Parikh , David S Gardner , Alan J Davidson , Veronika Sander , Min-Ae Song , Amandeep Bajwa , Navjot Singh Pabla

Kidney toxicity of the BRAF-kinase inhibitor vemurafenib is driven by off-target ferrochelatase inhibition.

Kidney international

Avec: Yuntao Bai , Ji Young Kim , Bijay Bisunke , Laura A Jayne , Josie A Silvaroli , Michael S Balzer , Megha Gandhi , Kevin M Huang , Veronika Sander , Jason Prosek , Rachel E Cianciolo , Sharyn D Baker , Alex Sparreboom , Kenar D Jhaveri , Katalin Susztak , Amandeep Bajwa , Navjot Singh Pabla

Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology.

bioRxiv : the preprint server for biology

Avec: Anna Castano , Margaux Silvestre , Carrow I Wells , Jennifer L Sanderson , Carla A Ferrer , Han Wee Ong , Yi Lang , William Richardson , Josie A Silvaroli , Frances M Bashore , Jeffery L Smith , Isabelle M Genereux , Kelvin Dempster , David H Drewry , Navlot S Pabla , Alex N Bullock , Tim A Benke , Sila Ultanir , Alison D Axtman

Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2.

bioRxiv : the preprint server for biology

Avec: Frances M Bashore , Sophia M Min , Xiangrong Chen , Stefanie Howell , Caroline H Rinderle , Gabriel Morel , Josie A Silvaroli , Carrow I Wells , Bruce A Bunnell , David H Drewry , Navjot S Pabla , Sila K Ultanir , Alex N Bullock , Alison D Axtman

Circadian clock disruption and growth of kidney cysts in autosomal dominant polycystic kidney disease.

bioRxiv : the preprint server for biology

Avec: Abeda Jamadar , Christopher J Ward , Viji Remadevi , Meekha M Varghese , Navjot S Pabla , Michelle L Gumz , Reena Rao

BMX kinase mediates gilteritinib resistance in FLT3-mutated AML through microenvironmental factors.

Blood advances

Avec: Daelynn R Buelow , Bhavana Bhatnagar , Shelley J Orwick , Jae Yoon Jeon , Eric D Eisenmann , Jack C Stromatt , Navjot Singh Pabla , James S Blachly , Sharyn D Baker , Bradley W Blaser

Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective.

ACS chemical neuroscience

Tubular mitochondrial pyruvate carrier disruption elicits redox adaptations that protect from acute kidney injury.

Molecular metabolism

Avec: Adam J Rauckhorst , Gabriela Vasquez Martinez , Gabriel Mayoral Andrade , Hsiang Wen , Ji Young Kim , Aaron Simoni , Claudia Robles-Planells , Kranti A Mapuskar , Prerna Rastogi , Emily J Steinbach , Michael L McCormick , Bryan G Allen , Navjot S Pabla , Ashley R Jackson , Mitchell C Coleman , Douglas R Spitz , Eric B Taylor , Diana Zepeda-Orozco

Genome-Wide CRISPR Screen Identifies Phospholipid Scramblase 3 as the Biological Target of Mitoprotective Drug SS-31.

Journal of the American Society of Nephrology : JASN

Avec: Josie A Silvaroli , Bijay Bisunke , Ji Young Kim , Amanda Stayton , Laura A Jayne , Shirely A Martinez , Christopher Nguyen , Prisha S Patel , Thitinee Vanichapol , Vivek Verma , Juheb Akhter , Subhashini Bolisetty , Sethu M Madhavan , Cem Kuscu , Christopher C Coss , Diana Zepeda-Orozco , Samir V Parikh , Anjali A Satoskar , Alan J Davidson , James D Eason , Hazel H Szeto , Navjot Singh Pabla , Amandeep Bajwa

A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury.

Nature communications

Avec: Ji Young Kim , Yuntao Bai , Laura A Jayne , Ralph D Hector , Avinash K Persaud , Su Sien Ong , Shreshtha Rojesh , Radhika Raj , Mei Ji He Ho Feng , Sangwoon Chung , Rachel E Cianciolo , John W Christman , Moray J Campbell , David S Gardner , Sharyn D Baker , Alex Sparreboom , Rajgopal Govindarajan , Harpreet Singh , Taosheng Chen , Ming Poi , Katalin Susztak , Stuart R Cobb , Navjot Singh Pabla

Involvement of the CDKL5-SOX9 signaling axis in rhabdomyolysis-associated acute kidney injury.

American journal of physiology. Renal physiology

Avec: Ji Young Kim , Yuntao Bai , Laura A Jayne , Rachel E Cianciolo , Amandeep Bajwa , Navjot Singh Pabla

IL-22 is secreted by proximal tubule cells and regulates DNA damage response and cell death in acute kidney injury.

Kidney international

Avec: Kensei Taguchi , Sho Sugahara , Bertha C Elias , Navjot S Pabla , Guillaume Canaud , Craig R Brooks

Tubular Mitochondrial Pyruvate Carrier Disruption Elicits Redox Adaptations that Protect from Acute Kidney Injury.

bioRxiv : the preprint server for biology

Avec: Adam J Rauckhorst , Gabriela Vasquez Martinez , Gabriel Mayoral Andrade , Hsiang Wen , Ji Young Kim , Aaron Simoni , Kranti A Mapuskar , Prerna Rastogi , Emily J Steinbach , Michael L McCormick , Bryan G Allen , Navjot S Pabla , Ashley R Jackson , Mitchell C Coleman , Douglas R Spitz , Eric B Taylor , Diana Zepeda-Orozco

Réseau de co-auteurs

Ji Young Kim 8 collaborations

Navjot Singh Pabla 7 collaborations

Navjot S Pabla 7 collaborations

Laura A Jayne 6 collaborations

Josie A Silvaroli 6 collaborations

Yuntao Bai 5 collaborations

Rachel E Cianciolo 4 collaborations

Carrow I Wells 4 collaborations

Alex N Bullock 4 collaborations

David H Drewry 4 collaborations

Alison D Axtman 4 collaborations

Amandeep Bajwa 4 collaborations

Han Wee Ong 3 collaborations

William Richardson 3 collaborations

Xiangrong Chen 3 collaborations

Margaux Silvestre 3 collaborations

Kelvin Dempster 3 collaborations

Jeffery L Smith 3 collaborations

Sila K Ultanir 3 collaborations

Sharyn D Baker 3 collaborations

Diana Zepeda-Orozco 3 collaborations

Mei Ji He Ho Feng 2 collaborations

Sangwoon Chung 2 collaborations

John W Christman 2 collaborations

Yi Liang 2 collaborations

Emily R Lowry 2 collaborations

Hynek Wichterle 2 collaborations

Megha Gandhi 2 collaborations

Samir V Parikh 2 collaborations

David S Gardner 2 collaborations

Alan J Davidson 2 collaborations

Veronika Sander 2 collaborations

Bijay Bisunke 2 collaborations

Alex Sparreboom 2 collaborations

Katalin Susztak 2 collaborations

Frances M Bashore 2 collaborations

Adam J Rauckhorst 2 collaborations

Gabriela Vasquez Martinez 2 collaborations

Gabriel Mayoral Andrade 2 collaborations

Hsiang Wen 2 collaborations

Aaron Simoni 2 collaborations

Kranti A Mapuskar 2 collaborations

Prerna Rastogi 2 collaborations

Emily J Steinbach 2 collaborations

Michael L McCormick 2 collaborations

Bryan G Allen 2 collaborations

Ashley R Jackson 2 collaborations

Mitchell C Coleman 2 collaborations

Douglas R Spitz 2 collaborations

Eric B Taylor 2 collaborations

Matthew A Clark 1 collaboration

Ferdos Abdulkader 1 collaboration

Tayla Perreau 1 collaboration

Min-Ae Song 1 collaboration

Michael S Balzer 1 collaboration

Kevin M Huang 1 collaboration

Jason Prosek 1 collaboration

Kenar D Jhaveri 1 collaboration

Anna Castano 1 collaboration

Jennifer L Sanderson 1 collaboration

Carla A Ferrer 1 collaboration

Yi Lang 1 collaboration

Isabelle M Genereux 1 collaboration

Tim A Benke 1 collaboration

Sila Ultanir 1 collaboration

Sophia M Min 1 collaboration

Stefanie Howell 1 collaboration

Caroline H Rinderle 1 collaboration

Gabriel Morel 1 collaboration

Bruce A Bunnell 1 collaboration

Abeda Jamadar 1 collaboration

Christopher J Ward 1 collaboration

Viji Remadevi 1 collaboration

Meekha M Varghese 1 collaboration

Michelle L Gumz 1 collaboration

Reena Rao 1 collaboration

Daelynn R Buelow 1 collaboration

Bhavana Bhatnagar 1 collaboration

Shelley J Orwick 1 collaboration

Jae Yoon Jeon 1 collaboration

Eric D Eisenmann 1 collaboration

Jack C Stromatt 1 collaboration

James S Blachly 1 collaboration

Bradley W Blaser 1 collaboration

Claudia Robles-Planells 1 collaboration

Amanda Stayton 1 collaboration

Shirely A Martinez 1 collaboration

Christopher Nguyen 1 collaboration

Prisha S Patel 1 collaboration

Thitinee Vanichapol 1 collaboration

Vivek Verma 1 collaboration

Juheb Akhter 1 collaboration

Subhashini Bolisetty 1 collaboration

Sethu M Madhavan 1 collaboration

Cem Kuscu 1 collaboration

Christopher C Coss 1 collaboration

Anjali A Satoskar 1 collaboration

James D Eason 1 collaboration

Hazel H Szeto 1 collaboration

Ralph D Hector 1 collaboration

Avinash K Persaud 1 collaboration

Su Sien Ong 1 collaboration

Shreshtha Rojesh 1 collaboration

Radhika Raj 1 collaboration

Moray J Campbell 1 collaboration

Rajgopal Govindarajan 1 collaboration

Harpreet Singh 1 collaboration

Taosheng Chen 1 collaboration

Ming Poi 1 collaboration

Stuart R Cobb 1 collaboration

Kensei Taguchi 1 collaboration

Sho Sugahara 1 collaboration

Bertha C Elias 1 collaboration

Guillaume Canaud 1 collaboration

Craig R Brooks 1 collaboration