Kranti A Mapuskar

Affiliations

Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa Hospitals & Clinics, Iowa City, IA, USA.

Publications (26)

Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes.

Cell metabolism

Avec: Calvin S Carter , Sunny C Huang , Charles C Searby , Benjamin Cassaidy , Michael J Miller , Wojciech J Grzesik , Ted B Piorczynski , Thomas K Pak , Susan A Walsh , Michael Acevedo , Qihong Zhang , Ginger L Milne , Antentor O Hinton , Deng-Fu Guo , Robert Weiss , Kyle Bradberry , Eric B Taylor , Adam J Rauckhorst , David W Dick , Vamsidhar Akurathi , Kelly C Falls-Hubert , Brett A Wagner , Walter A Carter , Kai Wang , Andrew W Norris , Kamal Rahmouni , Garry R Buettner , Jason M Hansen , Douglas R Spitz , E Dale Abel , Val C Sheffield

Quantitative MRI Evaluation of Ferritin Overexpression in Non-Small-Cell Lung Cancer.

International journal of molecular sciences

Avec: Mekhla Singhania , Amira Zaher , Casey F Pulliam , Khaliunaa Bayanbold , Charles C Searby , Joshua D Schoenfeld , Melissa A Fath , Bryan G Allen , Douglas R Spitz , Michael S Petronek

Avasopasem manganese (GC4419) protects against cisplatin-induced chronic kidney disease: An exploratory analysis of renal metrics from a randomized phase 2b clinical trial in head and neck cancer patients.

Redox biology

Avec: K A Mapuskar , G Vasquez Martinez , C F Pulliam , M S Petronek , E J Steinbach , V Monga , M Furqan , J G Jetton , D P Saunders , A Pearce , S Davidson , L Pitre , N E Dunlap , R Fairbanks , C M Lee , S L Mott , K L Bodeker , Huang Cl , J M Buatti , C M Anderson , R A Beardsley , J T Holmlund , D Zepeda-Orozco , D R Spitz , B G Allen

Redox Regulation of Nrf2 in Cisplatin-Induced Kidney Injury.

Antioxidants (Basel, Switzerland)

Avec: Casey F Pulliam , Diana Zepeda-Orozco , Benjamin R Griffin , Muhammad Furqan , Douglas R Spitz , Bryan G Allen

Combination Therapy with Radiation and PARP Inhibition Enhances Responsiveness to Anti-PD-1 Therapy in Colorectal Tumor Models.

International journal of radiation oncology, biology, physics

Avec: Steven N Seyedin , M M Hasibuzzaman , Vivan Pham , Michael S Petronek , Cameron Callaghan , Amanda L Kalen , Sarah L Mott , Douglas R Spitz , Bryan G Allen , Joseph M Caster

Neoadjuvant Radiotherapy-Related Wound Morbidity in Soft Tissue Sarcoma: Perspectives for Radioprotective Agents.

Cancers

Avec: Cameron M Callaghan , M M Hasibuzzaman , Samuel N Rodman , Jessica E Goetz , Michael S Petronek , Emily J Steinbach , Benjamin J Miller , Casey F Pulliam , Mitchell C Coleman , Varun V Monga , Mohammed M Milhem , Douglas R Spitz , Bryan G Allen

Depletion of Labile Iron Induces Replication Stress and Enhances Responses to Chemoradiation in Non-Small-Cell Lung Cancer.

Antioxidants (Basel, Switzerland)

Avec: Khaliunaa Bayanbold , Mekhla Singhania , Melissa A Fath , Charles C Searby , Jeffrey M Stolwijk , John B Henrich , Casey F Pulliam , Joshua D Schoenfeld , Sei Sho , Joseph M Caster , Bryan G Allen , Garry R Buettner , Maria Spies , Prabhat C Goswami , Michael S Petronek , Douglas R Spitz

The antioxidant and anti-inflammatory activities of avasopasem manganese in age-associated, cisplatin-induced renal injury.

Redox biology

Avec: Casey F Pulliam , Ann Tomanek-Chalkley , Prerna Rastogi , Hsiang Wen , Sanjana Dayal , Benjamin R Griffin , Diana Zepeda-Orozco , Amy L Sindler , Carryn M Anderson , Robert Beardsley , Eugene P Kennedy , Douglas R Spitz , Bryan G Allen

Tubular Mitochondrial Pyruvate Carrier Disruption Elicits Redox Adaptations that Protect from Acute Kidney Injury.

bioRxiv : the preprint server for biology

Avec: Adam J Rauckhorst , Gabriela Vasquez Martinez , Gabriel Mayoral Andrade , Hsiang Wen , Ji Young Kim , Aaron Simoni , Prerna Rastogi , Emily J Steinbach , Michael L McCormick , Bryan G Allen , Navjot S Pabla , Ashley R Jackson , Mitchell C Coleman , Douglas R Spitz , Eric B Taylor , Diana Zepeda-Orozco

Utilizing Superoxide Dismutase Mimetics to Enhance Radiation Therapy Response While Protecting Normal Tissues.

Seminars in radiation oncology

Avec: Carryn M Anderson , Douglas R Spitz , Ines Batinic-Haberle , Bryan G Allen , Rebecca E Oberley-Deegan

Succinate Accumulation Links Mitochondrial MnSOD Depletion to Aberrant Nuclear DNA Methylation and Altered Cell Fate.

Journal of Experimental Pathology

Avec: Kimberly L Cramer-Morales , Collin D Heer , Frederick E Domann

Magnetic resonance imaging (MRI) of pharmacological ascorbate-induced iron redox state as a biomarker in subjects undergoing radio-chemotherapy.

Redox biology

Avec: Cameron M Cushing , Michael S Petronek , Kellie L Bodeker , Sandy Vollstedt , Heather A Brown , Emyleigh Opat , Nancy J Hollenbeck , Thomas Shanks , Daniel J Berg , Brian J Smith , Mark C Smith , Varun Monga , Muhammad Furqan , Matthew A Howard , Jeremy D Greenlee , Joel St-Aubin , Ryan T Flynn , Joseph J Cullen , Garry R Buettner , Douglas R Spitz , John M Buatti , Bryan G Allen , Vincent A Magnotta

Mitochondrial Superoxide Dismutase in Cisplatin-Induced Kidney Injury.

Antioxidants (Basel, Switzerland)

Avec: Emily J Steinbach , Amira Zaher , Dennis P Riley , Robert A Beardsley , Jeffery L Keene , Jon T Holmlund , Carryn M Anderson , Diana Zepeda-Orozco , John M Buatti , Douglas R Spitz , Bryan G Allen

Manipulation of Redox Metabolism Using Pharmacologic Ascorbate Opens a Therapeutic Window for Radio-Sensitization by ATM Inhibitors in Colorectal Cancer.

International journal of radiation oncology, biology, physics

Avec: Cameron M Callaghan , Ibrahim M Abukhiran , Amr Masaadeh , Richard V Van Rheeden , Amanda L Kalen , Samuel N Rodman , Michael S Petronek , Benjamin N George , Mitchell C Coleman , Prabhat C Goswami , Bryan G Allen , Douglas R Spitz , Joseph M Caster

First-in-Human Phase I Clinical Trial of Pharmacologic Ascorbate Combined with Radiation and Temozolomide for Newly Diagnosed Glioblastoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Bryan G Allen , Kellie L Bodeker , Mark C Smith , Varun Monga , Sonia Sandhu , Raymond Hohl , Thomas Carlisle , Heather Brown , Nancy Hollenbeck , Sandy Vollstedt , Jeremy D Greenlee , Matthew A Howard , Steven N Seyedin , Joseph M Caster , Karra A Jones , Joseph J Cullen , Daniel Berg , Brett A Wagner , Garry R Buettner , Mindi J TenNapel , Brian J Smith , Douglas R Spitz , John M Buatti

Utilization of Pharmacological Ascorbate to Enhance Hydrogen Peroxide-Mediated Radiosensitivity in Cancer Therapy.

International journal of molecular sciences

Avec: Zain Mehdi , Michael S Petronek , Jeffrey M Stolwijk , Amanda L Kalen , Garry R Buettner , Joseph J Cullen , Douglas R Spitz , John M Buatti , Bryan G Allen

Rapid Peroxide Removal Limits the Radiosensitization of Diffuse Intrinsic Pontine Glioma (DIPG) Cells by Pharmacologic Ascorbate.

Radiation research

Avec: Shane R Solst , Claire H Graham , Sarah A King , Rana Rheem , Kyle Current , Bryan G Allen , Joseph M Caster , Douglas R Spitz , Michelle E Howard

Balanced Duality: H

International journal of molecular sciences

Avec: Amira Zaher , Michael S Petronek , Bryan G Allen ,

Superoxide Dismutase Mimetic Avasopasem Manganese Enhances Radiation Therapy Effectiveness in Soft Tissue Sarcomas and Accelerates Wound Healing.

Antioxidants (Basel, Switzerland)

Avec: Amira Zaher , Michael S Petronek , Munir R Tanas , Alexandra L Isaacson , Rebecca D Dodd , Mohammed Milhem , Muhammad Furqan , Douglas R Spitz , Benjamin J Miller , Robert A Beardsley , Bryan G Allen

Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis.

Cell reports

Avec: Sean C Tompkins , Ryan D Sheldon , Adam J Rauckhorst , Maria F Noterman , Shane R Solst , Jane L Buchanan , Alvin D Pewa , Lawrence R Gray , Lalita Oonthonpan , Arpit Sharma , Diego A Scerbo , Adam J Dupuy , Douglas R Spitz , Eric B Taylor

Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease.

Redox biology

Avec: Hsiang Wen , Danniele G Holanda , Prerna Rastogi , Emily Steinbach , Rachel Han , Mitchell C Coleman , Massimo Attanasio , Dennis P Riley , Douglas R Spitz , Bryan G Allen , Diana Zepeda-Orozco

Mitochondrial Oxidative Metabolism: An Emerging Therapeutic Target to Improve CKD Outcomes.

Biomedicines

Avec: Gabriela Vasquez-Martinez , Gabriel Mayoral-Andrade , Ann Tomanek-Chalkley , Diana Zepeda-Orozco , Bryan G Allen

Magnetic resonance imaging of iron metabolism with T2* mapping predicts an enhanced clinical response to pharmacological ascorbate in patients with GBM.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Michael S Petronek , Varun Monga , Kellie L Bodeker , Michael Kwofie , Chu-Yu Lee , Jeffrey M Stolwijk , Amira Zaher , Brett A Wagner , Mark C Smith , Sandy Vollstedt , Heather Brown , Meghan L Chandler , Amanda C Lorack , Jared S Wulfekuhle , Jann N Sarkaria , Ryan T Flynn , Jeremy D W Greenlee , Matthew A Howard , Brian J Smith , Karra A Jones , Garry R Buettner , Joseph J Cullen , Joel St-Aubin , John M Buatti , Vincent A Magnotta , Douglas R Spitz , Bryan G Allen

Tubular mitochondrial pyruvate carrier disruption elicits redox adaptations that protect from acute kidney injury.

Molecular metabolism

Avec: Adam J Rauckhorst , Gabriela Vasquez Martinez , Gabriel Mayoral Andrade , Hsiang Wen , Ji Young Kim , Aaron Simoni , Claudia Robles-Planells , Prerna Rastogi , Emily J Steinbach , Michael L McCormick , Bryan G Allen , Navjot S Pabla , Ashley R Jackson , Mitchell C Coleman , Douglas R Spitz , Eric B Taylor , Diana Zepeda-Orozco

Differential H

International journal of molecular sciences

Avec: Amira Zaher , Jann N Sarkaria , Douglas R Spitz , Michael S Petronek , Bryan G Allen

Radiation-Induced Macrovessel/Microvessel Disease.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Jun-Ichi Abe , Bryan G Allen , Andreas M Beyer , David Lewandowski , Vikram Subramanian , Michelle R Tamplin , Isabella M Grumbach

Réseau de co-auteurs

Bryan G Allen 22 collaborations

Douglas R Spitz 21 collaborations

Michael S Petronek 11 collaborations

Diana Zepeda-Orozco 7 collaborations

Garry R Buettner 6 collaborations

Amira Zaher 6 collaborations

Casey F Pulliam 5 collaborations

Joseph M Caster 5 collaborations

Mitchell C Coleman 5 collaborations

John M Buatti 5 collaborations

Eric B Taylor 4 collaborations

Adam J Rauckhorst 4 collaborations

Emily J Steinbach 4 collaborations

Prerna Rastogi 4 collaborations

Hsiang Wen 4 collaborations

Joseph J Cullen 4 collaborations

Charles C Searby 3 collaborations

Brett A Wagner 3 collaborations

Muhammad Furqan 3 collaborations

Amanda L Kalen 3 collaborations

Jeffrey M Stolwijk 3 collaborations

Carryn M Anderson 3 collaborations

Kellie L Bodeker 3 collaborations

Sandy Vollstedt 3 collaborations

Brian J Smith 3 collaborations

Mark C Smith 3 collaborations

Varun Monga 3 collaborations

Matthew A Howard 3 collaborations

Mekhla Singhania 2 collaborations

Khaliunaa Bayanbold 2 collaborations

Joshua D Schoenfeld 2 collaborations

Melissa A Fath 2 collaborations

Benjamin R Griffin 2 collaborations

Steven N Seyedin 2 collaborations

M M Hasibuzzaman 2 collaborations

Cameron M Callaghan 2 collaborations

Samuel N Rodman 2 collaborations

Benjamin J Miller 2 collaborations

Prabhat C Goswami 2 collaborations

Ann Tomanek-Chalkley 2 collaborations

Gabriela Vasquez Martinez 2 collaborations

Gabriel Mayoral Andrade 2 collaborations

Ji Young Kim 2 collaborations

Aaron Simoni 2 collaborations

Michael L McCormick 2 collaborations

Navjot S Pabla 2 collaborations

Ashley R Jackson 2 collaborations

Jeremy D Greenlee 2 collaborations

Joel St-Aubin 2 collaborations

Ryan T Flynn 2 collaborations

Vincent A Magnotta 2 collaborations

Dennis P Riley 2 collaborations

Robert A Beardsley 2 collaborations

Heather Brown 2 collaborations

Karra A Jones 2 collaborations

Shane R Solst 2 collaborations

Jann N Sarkaria 2 collaborations

Calvin S Carter 1 collaboration

Sunny C Huang 1 collaboration

Benjamin Cassaidy 1 collaboration

Michael J Miller 1 collaboration

Wojciech J Grzesik 1 collaboration

Ted B Piorczynski 1 collaboration

Thomas K Pak 1 collaboration

Susan A Walsh 1 collaboration

Michael Acevedo 1 collaboration

Qihong Zhang 1 collaboration

Ginger L Milne 1 collaboration

Antentor O Hinton 1 collaboration

Deng-Fu Guo 1 collaboration

Robert Weiss 1 collaboration

Kyle Bradberry 1 collaboration

David W Dick 1 collaboration

Vamsidhar Akurathi 1 collaboration

Kelly C Falls-Hubert 1 collaboration

Walter A Carter 1 collaboration

Kai Wang 1 collaboration

Andrew W Norris 1 collaboration

Kamal Rahmouni 1 collaboration

Jason M Hansen 1 collaboration

E Dale Abel 1 collaboration

Val C Sheffield 1 collaboration

K A Mapuskar 1 collaboration

G Vasquez Martinez 1 collaboration

C F Pulliam 1 collaboration

M S Petronek 1 collaboration

E J Steinbach 1 collaboration

V Monga 1 collaboration

M Furqan 1 collaboration

J G Jetton 1 collaboration

D P Saunders 1 collaboration

A Pearce 1 collaboration

S Davidson 1 collaboration

L Pitre 1 collaboration

N E Dunlap 1 collaboration

R Fairbanks 1 collaboration

C M Lee 1 collaboration

S L Mott 1 collaboration

K L Bodeker 1 collaboration

Huang Cl 1 collaboration

J M Buatti 1 collaboration

C M Anderson 1 collaboration

R A Beardsley 1 collaboration

J T Holmlund 1 collaboration

D Zepeda-Orozco 1 collaboration

D R Spitz 1 collaboration

B G Allen 1 collaboration

Vivan Pham 1 collaboration

Cameron Callaghan 1 collaboration

Sarah L Mott 1 collaboration

Jessica E Goetz 1 collaboration

Varun V Monga 1 collaboration

Mohammed M Milhem 1 collaboration

John B Henrich 1 collaboration

Sei Sho 1 collaboration

Maria Spies 1 collaboration

Sanjana Dayal 1 collaboration

Amy L Sindler 1 collaboration

Robert Beardsley 1 collaboration

Eugene P Kennedy 1 collaboration

Ines Batinic-Haberle 1 collaboration

Rebecca E Oberley-Deegan 1 collaboration

Kimberly L Cramer-Morales 1 collaboration

Collin D Heer 1 collaboration

Frederick E Domann 1 collaboration

Cameron M Cushing 1 collaboration

Heather A Brown 1 collaboration

Emyleigh Opat 1 collaboration

Nancy J Hollenbeck 1 collaboration

Thomas Shanks 1 collaboration

Daniel J Berg 1 collaboration

Jeffery L Keene 1 collaboration

Jon T Holmlund 1 collaboration

Ibrahim M Abukhiran 1 collaboration

Amr Masaadeh 1 collaboration

Richard V Van Rheeden 1 collaboration

Benjamin N George 1 collaboration

Sonia Sandhu 1 collaboration

Raymond Hohl 1 collaboration

Thomas Carlisle 1 collaboration

Nancy Hollenbeck 1 collaboration

Daniel Berg 1 collaboration

Mindi J TenNapel 1 collaboration

Zain Mehdi 1 collaboration

Claire H Graham 1 collaboration

Sarah A King 1 collaboration

Rana Rheem 1 collaboration

Kyle Current 1 collaboration

Michelle E Howard 1 collaboration

Munir R Tanas 1 collaboration

Alexandra L Isaacson 1 collaboration

Rebecca D Dodd 1 collaboration

Mohammed Milhem 1 collaboration

Sean C Tompkins 1 collaboration

Ryan D Sheldon 1 collaboration

Maria F Noterman 1 collaboration

Jane L Buchanan 1 collaboration

Alvin D Pewa 1 collaboration

Lawrence R Gray 1 collaboration

Lalita Oonthonpan 1 collaboration

Arpit Sharma 1 collaboration

Diego A Scerbo 1 collaboration

Adam J Dupuy 1 collaboration

Danniele G Holanda 1 collaboration

Emily Steinbach 1 collaboration

Rachel Han 1 collaboration

Massimo Attanasio 1 collaboration

Gabriela Vasquez-Martinez 1 collaboration

Gabriel Mayoral-Andrade 1 collaboration

Michael Kwofie 1 collaboration

Chu-Yu Lee 1 collaboration

Meghan L Chandler 1 collaboration

Amanda C Lorack 1 collaboration

Jared S Wulfekuhle 1 collaboration

Jeremy D W Greenlee 1 collaboration

Claudia Robles-Planells 1 collaboration

Jun-Ichi Abe 1 collaboration

Andreas M Beyer 1 collaboration

David Lewandowski 1 collaboration

Vikram Subramanian 1 collaboration

Michelle R Tamplin 1 collaboration

Isabella M Grumbach 1 collaboration