Leanna R Staben

Affiliations

Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.

Publications (4)

Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties.

Journal of medicinal chemistry

Avec: Peter S Dragovich , Thomas H Pillow , Robert A Blake , Jack D Sadowsky , Emel Adaligil , Pragya Adhikari , Sunil Bhakta , Nicole Blaquiere , Jinhua Chen , Josefa Dela Cruz-Chuh , Karen E Gascoigne , Steven J Hartman , Mingtao He , Susan Kaufman , Tracy Kleinheinz , Katherine R Kozak , Liang Liu , Liling Liu , Qi Liu , Ying Lu , Fanwei Meng , Melinda M Mulvihill , Aimee O'Donohue , Rebecca K Rowntree , Leanna R Staben , Steven T Staben , John Wai , Jian Wang , BinQing Wei , Catherine Wilson , Jianfeng Xin , Zijin Xu , Hui Yao , Donglu Zhang , Hongyan Zhang , Hao Zhou , Xiaoyu Zhu

PROTACs Targeting BRM (SMARCA2) Afford Selective

Journal of medicinal chemistry

Avec: Michael Berlin , Jennifer Cantley , Mark Bookbinder , Elizabeth Bortolon , Fabio Broccatelli , Greg Cadelina , Emily W Chan , Huifen Chen , Xin Chen , Yunxing Cheng , Tommy K Cheung , Kim Davenport , Dean DiNicola , Debbie Gordon , Brian D Hamman , Alicia Harbin , Roy Haskell , Mingtao He , Alison J Hole , Thomas Januario , Philip S Kerry , Stefan G Koenig , Limei Li , Mark Merchant , Inmaculada Pérez-Dorado , Jennifer Pizzano , Connor Quinn , Christopher M Rose , Emma Rousseau , Leofal Soto , Leanna R Staben , Hongming Sun , Qingping Tian , Jing Wang , Weifeng Wang , Crystal S Ye , Xiaofen Ye , Penghong Zhang , Yuhui Zhou , Robert Yauch , Peter S Dragovich

Systematic Variation of Pyrrolobenzodiazepine (PBD)-Dimer Payload Physicochemical Properties Impacts Efficacy and Tolerability of the Corresponding Antibody-Drug Conjugates.

Journal of medicinal chemistry

Avec: Leanna R Staben , Jinhua Chen , Josefa Dela Cruz-Chuh , Geoff Del Rosario , Mary Ann Go , Jun Guo , S Cyrus Khojasteh , Katherine R Kozak , Guangmin Li , Carl Ng , Gail D Lewis Phillips , Thomas H Pillow , Rebecca K Rowntree , John Wai , BinQing Wei , Keyang Xu , Zijin Xu , Shang-Fan Yu , Donglu Zhang , Peter S Dragovich

Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy.

Journal of medicinal chemistry

Avec: Peter S Dragovich , Thomas H Pillow , Robert A Blake , Jack D Sadowsky , Emel Adaligil , Pragya Adhikari , Jinhua Chen , Nicholas Corr , Josefa Dela Cruz-Chuh , Geoffrey Del Rosario , Aaron Fullerton , Steven J Hartman , Fan Jiang , Susan Kaufman , Tracy Kleinheinz , Katherine R Kozak , Liling Liu , Ying Lu , Melinda M Mulvihill , Jeremy M Murray , Aimee O'Donohue , Rebecca K Rowntree , William S Sawyer , Leanna R Staben , John Wai , Jian Wang , BinQing Wei , Wentao Wei , Zijin Xu , Hui Yao , Shang-Fan Yu , Donglu Zhang , Hongyan Zhang , Shenhua Zhang , Yongxin Zhao , Hao Zhou , Xiaoyu Zhu

Réseau de co-auteurs

Peter S Dragovich 4 collaborations

Thomas H Pillow 3 collaborations

Jinhua Chen 3 collaborations

Josefa Dela Cruz-Chuh 3 collaborations

Katherine R Kozak 3 collaborations

Rebecca K Rowntree 3 collaborations

John Wai 3 collaborations

BinQing Wei 3 collaborations

Zijin Xu 3 collaborations

Donglu Zhang 3 collaborations

Robert A Blake 2 collaborations

Jack D Sadowsky 2 collaborations

Emel Adaligil 2 collaborations

Pragya Adhikari 2 collaborations

Steven J Hartman 2 collaborations

Mingtao He 2 collaborations

Susan Kaufman 2 collaborations

Tracy Kleinheinz 2 collaborations

Liling Liu 2 collaborations

Ying Lu 2 collaborations

Melinda M Mulvihill 2 collaborations

Aimee O'Donohue 2 collaborations

Jian Wang 2 collaborations

Hui Yao 2 collaborations

Hongyan Zhang 2 collaborations

Hao Zhou 2 collaborations

Xiaoyu Zhu 2 collaborations

Shang-Fan Yu 2 collaborations

Sunil Bhakta 1 collaboration

Nicole Blaquiere 1 collaboration

Karen E Gascoigne 1 collaboration

Liang Liu 1 collaboration

Qi Liu 1 collaboration

Fanwei Meng 1 collaboration

Steven T Staben 1 collaboration

Catherine Wilson 1 collaboration

Jianfeng Xin 1 collaboration

Michael Berlin 1 collaboration

Jennifer Cantley 1 collaboration

Mark Bookbinder 1 collaboration

Elizabeth Bortolon 1 collaboration

Fabio Broccatelli 1 collaboration

Greg Cadelina 1 collaboration

Emily W Chan 1 collaboration

Huifen Chen 1 collaboration

Xin Chen 1 collaboration

Yunxing Cheng 1 collaboration

Tommy K Cheung 1 collaboration

Kim Davenport 1 collaboration

Dean DiNicola 1 collaboration

Debbie Gordon 1 collaboration

Brian D Hamman 1 collaboration

Alicia Harbin 1 collaboration

Roy Haskell 1 collaboration

Alison J Hole 1 collaboration

Thomas Januario 1 collaboration

Philip S Kerry 1 collaboration

Stefan G Koenig 1 collaboration

Limei Li 1 collaboration

Mark Merchant 1 collaboration

Inmaculada Pérez-Dorado 1 collaboration

Jennifer Pizzano 1 collaboration

Connor Quinn 1 collaboration

Christopher M Rose 1 collaboration

Emma Rousseau 1 collaboration

Leofal Soto 1 collaboration

Hongming Sun 1 collaboration

Qingping Tian 1 collaboration

Jing Wang 1 collaboration

Weifeng Wang 1 collaboration

Crystal S Ye 1 collaboration

Xiaofen Ye 1 collaboration

Penghong Zhang 1 collaboration

Yuhui Zhou 1 collaboration

Robert Yauch 1 collaboration

Geoff Del Rosario 1 collaboration

Mary Ann Go 1 collaboration

Jun Guo 1 collaboration

S Cyrus Khojasteh 1 collaboration

Guangmin Li 1 collaboration

Carl Ng 1 collaboration

Gail D Lewis Phillips 1 collaboration

Keyang Xu 1 collaboration

Nicholas Corr 1 collaboration

Geoffrey Del Rosario 1 collaboration

Aaron Fullerton 1 collaboration

Fan Jiang 1 collaboration

Jeremy M Murray 1 collaboration

William S Sawyer 1 collaboration

Wentao Wei 1 collaboration

Shenhua Zhang 1 collaboration

Yongxin Zhao 1 collaboration