Jennifer Pizzano

Affiliations

Arvinas LLC, 5 Science Park, New Haven, CT 06511, USA.

Publications (5)

Development of Liposome Systems for Enhancing the PK Properties of Bivalent PROTACs.

Pharmaceutics

Avec: Ponien Kou , Elizabeth S Levy , An D Nguyen , Donglu Zhang , Shu Chen , Yusi Cui , Xing Zhang , Fabio Broccatelli , Jennifer Pizzano , Jennifer Cantley , Elizabeth Bortolon , Emma Rousseau , Michael Berlin , Peter Dragovich , Vijay Sethuraman

PROTACs Targeting BRM (SMARCA2) Afford Selective

Journal of medicinal chemistry

Avec: Michael Berlin , Jennifer Cantley , Mark Bookbinder , Elizabeth Bortolon , Fabio Broccatelli , Greg Cadelina , Emily W Chan , Huifen Chen , Xin Chen , Yunxing Cheng , Tommy K Cheung , Kim Davenport , Dean DiNicola , Debbie Gordon , Brian D Hamman , Alicia Harbin , Roy Haskell , Mingtao He , Alison J Hole , Thomas Januario , Philip S Kerry , Stefan G Koenig , Limei Li , Mark Merchant , Inmaculada Pérez-Dorado , Jennifer Pizzano , Connor Quinn , Christopher M Rose , Emma Rousseau , Leofal Soto , Leanna R Staben , Hongming Sun , Qingping Tian , Jing Wang , Weifeng Wang , Crystal S Ye , Xiaofen Ye , Penghong Zhang , Yuhui Zhou , Robert Yauch , Peter S Dragovich

Tissue distribution and retention drives efficacy of rapidly clearing VHL-based PROTACs.

Communications medicine

Avec: Donglu Zhang , Bin Ma , Peter S Dragovich , Li Ma , Shu Chen , Eugene C Chen , Xiaofen Ye , Joyce Liu , Jennifer Pizzano , Elizabeth Bortolon , Emily Chan , Xing Zhang , Yi-Chen Chen , Elizabeth S Levy , Robert L Yauch , S Cyrus Khojasteh , Cornelis E C A Hop

Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers.

Nature communications

Avec: Jennifer Cantley , Xiaofen Ye , Emma Rousseau , Tom Januario , Brian D Hamman , Christopher M Rose , Tommy K Cheung , Trent Hinkle , Leofal Soto , Connor Quinn , Alicia Harbin , Elizabeth Bortolon , Xin Chen , Roy Haskell , Eva Lin , Shang-Fan Yu , Geoff Del Rosario , Emily Chan , Debra Dunlap , Hartmut Koeppen , Scott Martin , Mark Merchant , Matt Grimmer , Fabio Broccatelli , Jing Wang , Jennifer Pizzano , Peter S Dragovich , Michael Berlin , Robert L Yauch

Oral estrogen receptor PROTAC® vepdegestrant (ARV-471) is highly efficacious as monotherapy and in combination with CDK4/6 or PI3K/mTOR pathway inhibitors in preclinical ER+ breast cancer models.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Sheryl M Gough , John J Flanagan , Jessica Teh , Monica Andreoli , Emma Rousseau , Melissa Pannone , Mark Bookbinder , Ryan Willard , Kim Davenport , Elizabeth Bortolon , Gregory Cadelina , Deborah Gordon , Jennifer Pizzano , Jennifer Macaluso , Leofal Soto , John Corradi , Katherine Digianantonio , Ieva Drulyte , Alicia Morgan , Connor Quinn , Miklós Békés , Caterina Ferraro , Xin Chen , Gan Wang , Hanqing Dong , Jing Wang , David R Langley , John Houston , Richard Gedrich , Ian C Taylor

Réseau de co-auteurs

Elizabeth Bortolon 5 collaborations

Emma Rousseau 4 collaborations

Fabio Broccatelli 3 collaborations

Jennifer Cantley 3 collaborations

Michael Berlin 3 collaborations

Xin Chen 3 collaborations

Connor Quinn 3 collaborations

Leofal Soto 3 collaborations

Jing Wang 3 collaborations

Xiaofen Ye 3 collaborations

Peter S Dragovich 3 collaborations

Elizabeth S Levy 2 collaborations

Donglu Zhang 2 collaborations

Shu Chen 2 collaborations

Xing Zhang 2 collaborations

Mark Bookbinder 2 collaborations

Tommy K Cheung 2 collaborations

Kim Davenport 2 collaborations

Brian D Hamman 2 collaborations

Alicia Harbin 2 collaborations

Roy Haskell 2 collaborations

Mark Merchant 2 collaborations

Christopher M Rose 2 collaborations

Emily Chan 2 collaborations

Robert L Yauch 2 collaborations

Ponien Kou 1 collaboration

An D Nguyen 1 collaboration

Yusi Cui 1 collaboration

Peter Dragovich 1 collaboration

Vijay Sethuraman 1 collaboration

Greg Cadelina 1 collaboration

Emily W Chan 1 collaboration

Huifen Chen 1 collaboration

Yunxing Cheng 1 collaboration

Dean DiNicola 1 collaboration

Debbie Gordon 1 collaboration

Mingtao He 1 collaboration

Alison J Hole 1 collaboration

Thomas Januario 1 collaboration

Philip S Kerry 1 collaboration

Stefan G Koenig 1 collaboration

Limei Li 1 collaboration

Inmaculada Pérez-Dorado 1 collaboration

Leanna R Staben 1 collaboration

Hongming Sun 1 collaboration

Qingping Tian 1 collaboration

Weifeng Wang 1 collaboration

Crystal S Ye 1 collaboration

Penghong Zhang 1 collaboration

Yuhui Zhou 1 collaboration

Robert Yauch 1 collaboration

Bin Ma 1 collaboration

Li Ma 1 collaboration

Eugene C Chen 1 collaboration

Joyce Liu 1 collaboration

Yi-Chen Chen 1 collaboration

S Cyrus Khojasteh 1 collaboration

Cornelis E C A Hop 1 collaboration

Tom Januario 1 collaboration

Trent Hinkle 1 collaboration

Eva Lin 1 collaboration

Shang-Fan Yu 1 collaboration

Geoff Del Rosario 1 collaboration

Debra Dunlap 1 collaboration

Hartmut Koeppen 1 collaboration

Scott Martin 1 collaboration

Matt Grimmer 1 collaboration

Sheryl M Gough 1 collaboration

John J Flanagan 1 collaboration

Jessica Teh 1 collaboration

Monica Andreoli 1 collaboration

Melissa Pannone 1 collaboration

Ryan Willard 1 collaboration

Gregory Cadelina 1 collaboration

Deborah Gordon 1 collaboration

Jennifer Macaluso 1 collaboration

John Corradi 1 collaboration

Katherine Digianantonio 1 collaboration

Ieva Drulyte 1 collaboration

Alicia Morgan 1 collaboration

Miklós Békés 1 collaboration

Caterina Ferraro 1 collaboration

Gan Wang 1 collaboration

Hanqing Dong 1 collaboration

David R Langley 1 collaboration

John Houston 1 collaboration

Richard Gedrich 1 collaboration

Ian C Taylor 1 collaboration