Sachie Kanatani

Affiliations

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

ORCID: 0000-0002-7072-0447

Publications (25)

Screening the Pathogen Box for Inhibition of Plasmodium falciparum Sporozoite Motility Reveals a Critical Role for Kinases in Transmission Stages.

Antimicrobial agents and chemotherapy

Avec: Rubayet Elahi , Sukanat Kanchanabhogin , Natasha Vartak , Abhai K Tripathi , Sean T Prigge , Photini Sinnis

Anatomy of the complete mouse eye vasculature explored by light-sheet fluorescence microscopy exposes subvascular-specific remodeling in development and pathology.

Experimental eye research

Avec: Luc Thomas Krimpenfort , Maria Garcia-Collado , Tom van Leeuwen , Filippo Locri , Anna-Liisa Luik , Antonio Queiro-Palou , Shigeaki Kanatani , Helder André , Per Uhlén , Lars Jakobsson

Spatial dynamics of mammalian brain development and neuroinflammation by multimodal tri-omics mapping.

bioRxiv : the preprint server for biology

Avec: Di Zhang , Leslie A Rubio Rodríguez-Kirby , Yingxin Lin , Mengyi Song , Li Wang , Lijun Wang , Shigeaki Kanatani , Tony Jimenez-Beristain , Yonglong Dang , Mei Zhong , Petra Kukanja , Shaohui Wang , Xinyi Lisa Chen , Fu Gao , Dejiang Wang , Hang Xu , Xing Lou , Yang Liu , Jinmiao Chen , Nenad Sestan , Per Uhlén , Arnold Kriegstein , Hongyu Zhao , Gonçalo Castelo-Branco , Rong Fan

GABAergic signaling in human and murine NK cells upon challenge with Toxoplasma gondii.

Journal of leukocyte biology

Avec: Amol K Bhandage , Laura M Friedrich , Simon Jakobsson-Björkén , J Ignacio Escrig-Larena , Arnika K Wagner , Benedict J Chambers , Antonio Barragan

Disrupted

Proceedings of the National Academy of Sciences of the United States of America

Avec: Erik Smedler , Lauri Louhivuori , Roman A Romanov , Débora Masini , Ivar Dehnisch Ellström , Chungliang Wang , Martino Caramia , Zoe West , Songbai Zhang , Paola Rebellato , Seth Malmersjö , Irene Brusini , Shigeaki Kanatani , Gilberto Fisone , Tibor Harkany , Per Uhlén

Three-dimensional imaging of upper tract urothelial carcinoma improves diagnostic yield and accuracy.

JCI insight

Avec: Keishiro Fukumoto , Shigeaki Kanatani , Georg Jaremko , Zoe West , Yue Li , Kimiharu Takamatsu , Ibrahim Al Rayyes , Shuji Mikami , Naoya Niwa , Tomas Andri Axelsson , Nobuyuki Tanaka , Mototsugu Oya , Ayako Miyakawa , Marianne Brehmer , Per Uhlén

Transcriptional heterogeneity and tightly regulated changes in gene expression during

Proceedings of the National Academy of Sciences of the United States of America

Avec: Haikel N Bogale , Tales V Pascini , Juliana M Sá , Thomas E Wellems , Photini Sinnis , Joel Vega-Rodríguez , David Serre

Spatial dynamics of mammalian brain development and neuroinflammation by multimodal tri-omics mapping.

Research square

Avec: Rong Fan , Di Zhang , Leslie Rodríguez-Kirby , Yingxin Lin , Mengyi Song , Li Wang , Lijun Wang , Shigeaki Kanatani , Tony Jimenez-Beristain , Yonglong Dang , Mei Zhong , Petra Kukanja , Shaohui Wang , Xinyi Chen , Fu Gao , Dejiang Wang , Hang Xu , Xing Lou , Yang Liu , Jinmiao Chen , Nenad Sestan , Per Uhlen , Arnold R Kriegstein , Hongyu Zhao , Goncalo Castelo-Branco

The major surface protein of malaria sporozoites is GPI-anchored to the plasma membrane.

The Journal of biological chemistry

Avec: Rupa Nagar , Stefano S Garcia Castillo , Maria Pinzon-Ortiz , Sharon Patray , Alida Coppi , Robert L Moritz , Kristian E Swearingen , Michael A J Ferguson , Photini Sinnis

Notch activation in the mouse mammary luminal lineage leads to ductal hyperplasia and altered partitioning of luminal cell subtypes.

Experimental cell research

Avec: Yee Peng Phoon , Indira V Chivukula , Yat Long Tsoi , Shigeaki Kanatani , Per Uhlén , Raoul Kuiper , Urban Lendahl

Three-dimensional single-cell imaging for the analysis of RNA and protein expression in intact tumour biopsies.

Nature biomedical engineering

Avec: Nobuyuki Tanaka , Shigeaki Kanatani , Dagmara Kaczynska , Keishiro Fukumoto , Lauri Louhivuori , Tomohiro Mizutani , Oded Kopper , Pauliina Kronqvist , Stephanie Robertson , Claes Lindh , Lorand Kis , Robin Pronk , Naoya Niwa , Kazuhiro Matsumoto , Mototsugu Oya , Ayako Miyakawa , Anna Falk , Johan Hartman , Cecilia Sahlgren , Hans Clevers , Per Uhlén

A motogenic GABAergic system of mononuclear phagocytes facilitates dissemination of coccidian parasites.

eLife

Avec: Amol K Bhandage , Gabriela C Olivera , Elizabeth Thompson , Karin Loré , Manuel Varas-Godoy , Antonio Barragan

Comparative intravital imaging of human and rodent malaria sporozoites reveals the skin is not a species-specific barrier.

EMBO molecular medicine

Avec: Christine S Hopp , Nathan K Archer , Robert J Miller , Haiyun Liu , Kevin K Chiou , Lloyd S Miller , Photini Sinnis

Revisiting the Plasmodium sporozoite inoculum and elucidating the efficiency with which malaria parasites progress through the mosquito.

Nature communications

Avec: Deborah Stiffler , Teun Bousema , Gayane Yenokyan , Photini Sinnis

Plasmodium falciparum Gametocyte Culture and Mosquito Infection Through Artificial Membrane Feeding.

Journal of visualized experiments : JoVE

Avec: Abhai K Tripathi , Godfree Mlambo , Photini Sinnis , George Dimopoulos

The T-type Ca

Neuroscience

Avec: Paola Rebellato , Dagmara Kaczynska , Shigeaki Kanatani , Ibrahim Al Rayyes , Songbai Zhang , Carlos Villaescusa , Anna Falk , Ernest Arenas , Ola Hermanson , Lauri Louhivuori , Per Uhlén

Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters.

Scientific reports

Avec: Kyle Jarrod McLean , Judith Straimer , Christine S Hopp , Joel Vega-Rodriguez , Jennifer L Small-Saunders , Abhai Tripathi , Godfree Mlambo , Peter C Dumoulin , Chantal T Harris , Xinran Tong , Melanie J Shears , Johan Ankarklev , Björn F C Kafsack , David A Fidock , Photini Sinnis

Targeting a scavenger receptor on tumor-associated macrophages activates tumor cell killing by natural killer cells.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Silke Eisinger , Dhifaf Sarhan , Vanessa F Boura , Itziar Ibarlucea-Benitez , Sofia Tyystjärvi , Ganna Oliynyk , Marie Arsenian-Henriksson , David Lane , Stina L Wikström , Rolf Kiessling , Tommaso Virgilio , Santiago F Gonzalez , Dagmara Kaczynska , Shigeaki Kanatani , Evangelia Daskalaki , Craig E Wheelock , Saikiran Sedimbi , Benedict J Chambers , Jeffrey V Ravetch , Mikael C I Karlsson

Functional human IgA targets a conserved site on malaria sporozoites.

Science translational medicine

Avec: Joshua Tan , Hyeseon Cho , Tossapol Pholcharee , Lais S Pereira , Safiatou Doumbo , Didier Doumtabe , Barbara J Flynn , Arne Schön , Samantha O Aylor , David Oyen , Rachel Vistein , Lawrence Wang , Marlon Dillon , Jeff Skinner , Mary Peterson , Shanping Li , Azza H Idris , Alvaro Molina-Cruz , Ming Zhao , Lisa Renee Olano , Patricia J Lee , Alison Roth , Photini Sinnis , Carolina Barillas-Mury , Kassoum Kayentao , Aissata Ongoiba , Joseph R Francica , Boubacar Traore , Ian A Wilson , Robert A Seder , Peter D Crompton

Spatial Transcriptomics to define transcriptional patterns of zonation and structural components in the mouse liver.

Nature communications

Avec: Franziska Hildebrandt , Alma Andersson , Sami Saarenpää , Ludvig Larsson , Noémi Van Hul , Jan Masek , Ewa Ellis , Antonio Barragan , Annelie Mollbrink , Emma R Andersson , Joakim Lundeberg , Johan Ankarklev

GIT1 protects against breast cancer growth through negative regulation of Notch.

Nature communications

Avec: Songbai Zhang , Ayako Miyakawa , Malin Wickström , Cecilia Dyberg , Lauri Louhivuori , Manuel Varas-Godoy , Kati Kemppainen , Shigeaki Kanatani , Dagmara Kaczynska , Ivar Dehnisch Ellström , Lotta Elfman , Pauliina Kronqvist , Heli Repo , Katsuhiko Mikoshiba , Cecilia Sahlgren , John Inge Johnsen , Per Uhlén

Spatiotemporal characterization of cellular tau pathology in the human locus coeruleus-pericoerulear complex by three-dimensional imaging.

Acta neuropathologica

Avec: Abris Gilvesy , Evelina Husen , Zsofia Magloczky , Orsolya Mihaly , Tibor Hortobágyi , Shigeaki Kanatani , Helmut Heinsen , Nicolas Renier , Tomas Hökfelt , Jan Mulder , Mathias Uhlen , Gabor G Kovacs , Csaba Adori

Directionality of developing skeletal muscles is set by mechanical forces.

Nature communications

Avec: Kazunori Sunadome , Alek G Erickson , Delf Kah , Ben Fabry , Csaba Adori , Polina Kameneva , Louis Faure , Shigeaki Kanatani , Marketa Kaucka , Ivar Dehnisch Ellström , Marketa Tesarova , Tomas Zikmund , Jozef Kaiser , Steven Edwards , Koichiro Maki , Taiji Adachi , Takuya Yamamoto , Kaj Fried , Igor Adameyko

ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain.

Nature neuroscience

Avec: Vassilis Stratoulias , Rocío Ruiz , Shigeaki Kanatani , Ahmed M Osman , Lily Keane , Jose A Armengol , Antonio Rodríguez-Moreno , Adriana-Natalia Murgoci , Irene García-Domínguez , Isabel Alonso-Bellido , Fernando González Ibáñez , Katherine Picard , Guillermo Vázquez-Cabrera , Mercedes Posada-Pérez , Nathalie Vernoux , Dario Tejera , Kathleen Grabert , Mathilde Cheray , Patricia González-Rodríguez , Eva M Pérez-Villegas , Irene Martínez-Gallego , Alejandro Lastra-Romero , David Brodin , Javier Avila-Cariño , Yang Cao , Mikko Airavaara , Per Uhlén , Michael T Heneka , Marie-Ève Tremblay , Klas Blomgren , Jose L Venero , Bertrand Joseph

The major surface protein of malaria sporozoites is GPI-anchored to the plasma membrane.

bioRxiv : the preprint server for biology

Avec: Rupa Nagar , Stefano S Garcia Castillo , Maria Pinzon-Ortiz , Sharon Patray , Alida Coppi , Robert L Moritz , Kristian E Swearingen , Michael A J Ferguson , Photini Sinnis

Réseau de co-auteurs

Shigeaki Kanatani 13 collaborations

Photini Sinnis 9 collaborations

Per Uhlén 9 collaborations

Lauri Louhivuori 4 collaborations

Dagmara Kaczynska 4 collaborations

Antonio Barragan 3 collaborations

Ivar Dehnisch Ellström 3 collaborations

Songbai Zhang 3 collaborations

Ayako Miyakawa 3 collaborations

Abhai K Tripathi 2 collaborations

Di Zhang 2 collaborations

Yingxin Lin 2 collaborations

Mengyi Song 2 collaborations

Li Wang 2 collaborations

Lijun Wang 2 collaborations

Tony Jimenez-Beristain 2 collaborations

Yonglong Dang 2 collaborations

Mei Zhong 2 collaborations

Petra Kukanja 2 collaborations

Shaohui Wang 2 collaborations

Fu Gao 2 collaborations

Dejiang Wang 2 collaborations

Hang Xu 2 collaborations

Xing Lou 2 collaborations

Yang Liu 2 collaborations

Jinmiao Chen 2 collaborations

Nenad Sestan 2 collaborations

Hongyu Zhao 2 collaborations

Rong Fan 2 collaborations

Amol K Bhandage 2 collaborations

Benedict J Chambers 2 collaborations

Zoe West 2 collaborations

Paola Rebellato 2 collaborations

Keishiro Fukumoto 2 collaborations

Ibrahim Al Rayyes 2 collaborations

Naoya Niwa 2 collaborations

Nobuyuki Tanaka 2 collaborations

Mototsugu Oya 2 collaborations

Rupa Nagar 2 collaborations

Stefano S Garcia Castillo 2 collaborations

Maria Pinzon-Ortiz 2 collaborations

Sharon Patray 2 collaborations

Alida Coppi 2 collaborations

Robert L Moritz 2 collaborations

Kristian E Swearingen 2 collaborations

Michael A J Ferguson 2 collaborations

Pauliina Kronqvist 2 collaborations

Anna Falk 2 collaborations

Cecilia Sahlgren 2 collaborations

Manuel Varas-Godoy 2 collaborations

Christine S Hopp 2 collaborations

Godfree Mlambo 2 collaborations

Johan Ankarklev 2 collaborations

Csaba Adori 2 collaborations

Rubayet Elahi 1 collaboration

Sukanat Kanchanabhogin 1 collaboration

Natasha Vartak 1 collaboration

Sean T Prigge 1 collaboration

Luc Thomas Krimpenfort 1 collaboration

Maria Garcia-Collado 1 collaboration

Tom van Leeuwen 1 collaboration

Filippo Locri 1 collaboration

Anna-Liisa Luik 1 collaboration

Antonio Queiro-Palou 1 collaboration

Helder André 1 collaboration

Lars Jakobsson 1 collaboration

Leslie A Rubio Rodríguez-Kirby 1 collaboration

Xinyi Lisa Chen 1 collaboration

Arnold Kriegstein 1 collaboration

Gonçalo Castelo-Branco 1 collaboration

Laura M Friedrich 1 collaboration

Simon Jakobsson-Björkén 1 collaboration

J Ignacio Escrig-Larena 1 collaboration

Arnika K Wagner 1 collaboration

Erik Smedler 1 collaboration

Roman A Romanov 1 collaboration

Débora Masini 1 collaboration

Chungliang Wang 1 collaboration

Martino Caramia 1 collaboration

Seth Malmersjö 1 collaboration

Irene Brusini 1 collaboration

Gilberto Fisone 1 collaboration

Tibor Harkany 1 collaboration

Georg Jaremko 1 collaboration

Yue Li 1 collaboration

Kimiharu Takamatsu 1 collaboration

Shuji Mikami 1 collaboration

Tomas Andri Axelsson 1 collaboration

Marianne Brehmer 1 collaboration

Haikel N Bogale 1 collaboration

Tales V Pascini 1 collaboration

Juliana M Sá 1 collaboration

Thomas E Wellems 1 collaboration

Joel Vega-Rodríguez 1 collaboration

David Serre 1 collaboration

Leslie Rodríguez-Kirby 1 collaboration

Xinyi Chen 1 collaboration

Per Uhlen 1 collaboration

Arnold R Kriegstein 1 collaboration

Goncalo Castelo-Branco 1 collaboration

Yee Peng Phoon 1 collaboration

Indira V Chivukula 1 collaboration

Yat Long Tsoi 1 collaboration

Raoul Kuiper 1 collaboration

Urban Lendahl 1 collaboration

Tomohiro Mizutani 1 collaboration

Oded Kopper 1 collaboration

Stephanie Robertson 1 collaboration

Claes Lindh 1 collaboration

Lorand Kis 1 collaboration

Robin Pronk 1 collaboration

Kazuhiro Matsumoto 1 collaboration

Johan Hartman 1 collaboration

Hans Clevers 1 collaboration

Gabriela C Olivera 1 collaboration

Elizabeth Thompson 1 collaboration

Karin Loré 1 collaboration

Nathan K Archer 1 collaboration

Robert J Miller 1 collaboration

Haiyun Liu 1 collaboration

Kevin K Chiou 1 collaboration

Lloyd S Miller 1 collaboration

Deborah Stiffler 1 collaboration

Teun Bousema 1 collaboration

Gayane Yenokyan 1 collaboration

George Dimopoulos 1 collaboration

Carlos Villaescusa 1 collaboration

Ernest Arenas 1 collaboration

Ola Hermanson 1 collaboration

Kyle Jarrod McLean 1 collaboration

Judith Straimer 1 collaboration

Joel Vega-Rodriguez 1 collaboration

Jennifer L Small-Saunders 1 collaboration

Abhai Tripathi 1 collaboration

Peter C Dumoulin 1 collaboration

Chantal T Harris 1 collaboration

Xinran Tong 1 collaboration

Melanie J Shears 1 collaboration

Björn F C Kafsack 1 collaboration

David A Fidock 1 collaboration

Silke Eisinger 1 collaboration

Dhifaf Sarhan 1 collaboration

Vanessa F Boura 1 collaboration

Itziar Ibarlucea-Benitez 1 collaboration

Sofia Tyystjärvi 1 collaboration

Ganna Oliynyk 1 collaboration

Marie Arsenian-Henriksson 1 collaboration

David Lane 1 collaboration

Stina L Wikström 1 collaboration

Rolf Kiessling 1 collaboration

Tommaso Virgilio 1 collaboration

Santiago F Gonzalez 1 collaboration

Evangelia Daskalaki 1 collaboration

Craig E Wheelock 1 collaboration

Saikiran Sedimbi 1 collaboration

Jeffrey V Ravetch 1 collaboration

Mikael C I Karlsson 1 collaboration

Joshua Tan 1 collaboration

Hyeseon Cho 1 collaboration

Tossapol Pholcharee 1 collaboration

Lais S Pereira 1 collaboration

Safiatou Doumbo 1 collaboration

Didier Doumtabe 1 collaboration

Barbara J Flynn 1 collaboration

Arne Schön 1 collaboration

Samantha O Aylor 1 collaboration

David Oyen 1 collaboration

Rachel Vistein 1 collaboration

Lawrence Wang 1 collaboration

Marlon Dillon 1 collaboration

Jeff Skinner 1 collaboration

Mary Peterson 1 collaboration

Shanping Li 1 collaboration

Azza H Idris 1 collaboration

Alvaro Molina-Cruz 1 collaboration

Ming Zhao 1 collaboration

Lisa Renee Olano 1 collaboration

Patricia J Lee 1 collaboration

Alison Roth 1 collaboration

Carolina Barillas-Mury 1 collaboration

Kassoum Kayentao 1 collaboration

Aissata Ongoiba 1 collaboration

Joseph R Francica 1 collaboration

Boubacar Traore 1 collaboration

Ian A Wilson 1 collaboration

Robert A Seder 1 collaboration

Peter D Crompton 1 collaboration

Franziska Hildebrandt 1 collaboration

Alma Andersson 1 collaboration

Sami Saarenpää 1 collaboration

Ludvig Larsson 1 collaboration

Noémi Van Hul 1 collaboration

Jan Masek 1 collaboration

Ewa Ellis 1 collaboration

Annelie Mollbrink 1 collaboration

Emma R Andersson 1 collaboration

Joakim Lundeberg 1 collaboration

Malin Wickström 1 collaboration

Cecilia Dyberg 1 collaboration

Kati Kemppainen 1 collaboration

Lotta Elfman 1 collaboration

Heli Repo 1 collaboration

Katsuhiko Mikoshiba 1 collaboration

John Inge Johnsen 1 collaboration

Abris Gilvesy 1 collaboration

Evelina Husen 1 collaboration

Zsofia Magloczky 1 collaboration

Orsolya Mihaly 1 collaboration

Tibor Hortobágyi 1 collaboration

Helmut Heinsen 1 collaboration

Nicolas Renier 1 collaboration

Tomas Hökfelt 1 collaboration

Jan Mulder 1 collaboration

Mathias Uhlen 1 collaboration

Gabor G Kovacs 1 collaboration

Kazunori Sunadome 1 collaboration

Alek G Erickson 1 collaboration

Delf Kah 1 collaboration

Ben Fabry 1 collaboration

Polina Kameneva 1 collaboration

Louis Faure 1 collaboration

Marketa Kaucka 1 collaboration

Marketa Tesarova 1 collaboration

Tomas Zikmund 1 collaboration

Jozef Kaiser 1 collaboration

Steven Edwards 1 collaboration

Koichiro Maki 1 collaboration

Taiji Adachi 1 collaboration

Takuya Yamamoto 1 collaboration

Kaj Fried 1 collaboration

Igor Adameyko 1 collaboration

Vassilis Stratoulias 1 collaboration

Rocío Ruiz 1 collaboration

Ahmed M Osman 1 collaboration

Lily Keane 1 collaboration

Jose A Armengol 1 collaboration

Antonio Rodríguez-Moreno 1 collaboration

Adriana-Natalia Murgoci 1 collaboration

Irene García-Domínguez 1 collaboration

Isabel Alonso-Bellido 1 collaboration

Fernando González Ibáñez 1 collaboration

Katherine Picard 1 collaboration

Guillermo Vázquez-Cabrera 1 collaboration

Mercedes Posada-Pérez 1 collaboration

Nathalie Vernoux 1 collaboration

Dario Tejera 1 collaboration

Kathleen Grabert 1 collaboration

Mathilde Cheray 1 collaboration

Patricia González-Rodríguez 1 collaboration

Eva M Pérez-Villegas 1 collaboration

Irene Martínez-Gallego 1 collaboration

Alejandro Lastra-Romero 1 collaboration

David Brodin 1 collaboration

Javier Avila-Cariño 1 collaboration

Yang Cao 1 collaboration

Mikko Airavaara 1 collaboration

Michael T Heneka 1 collaboration

Marie-Ève Tremblay 1 collaboration

Klas Blomgren 1 collaboration

Jose L Venero 1 collaboration

Bertrand Joseph 1 collaboration