Melanie J Shears

Affiliations

Department of Molecular Microbiology and Immunology, and Johns Hopkins Malaria Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA.
Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA, 98109, USA.

Publications (11)

Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters.

Scientific reports

Avec: Kyle Jarrod McLean , Judith Straimer , Christine S Hopp , Joel Vega-Rodriguez , Jennifer L Small-Saunders , Sachie Kanatani , Abhai Tripathi , Godfree Mlambo , Peter C Dumoulin , Chantal T Harris , Xinran Tong , Melanie J Shears , Johan Ankarklev , Björn F C Kafsack , David A Fidock , Photini Sinnis

Sex-Specific Differences in Cytokine Induction by the Glycolipid Adjuvant 7DW8-5 in Mice.

Biomolecules

Avec: Felicia N Watson , Caroline J Duncombe , Anya C Kalata , Ethan Conrad , Sumana Chakravarty , B Kim Lee Sim , Stephen L Hoffman , Moriya Tsuji , Melanie J Shears , Sean C Murphy

Accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine.

NPJ vaccines

Avec: Zachary MacMillen , Kiara Hatzakis , Adrian Simpson , Melanie J Shears , Felicia Watson , Jesse H Erasmus , Amit P Khandhar , Brandon Wilder , Sean C Murphy , Steven G Reed , James W Davie , Marion Avril

More time to kill: A longer liver stage increases T cell-mediated protection against pre-erythrocytic malaria.

iScience

Avec: Naveen Yadav , Chaitra Parthiban , Zachary P Billman , Brad C Stone , Felicia N Watson , Kevin Zhou , Tayla M Olsen , Irene Cruz Talavera , Annette Mariko Seilie , Anya C Kalata , Jokichi Matsubara , Melanie J Shears , Rebekah A Reynolds , Sean C Murphy

Vancomycin improves Plasmodium yoelii malaria parasite in vitro liver stage cultures by controlling Elizabethkingia anophelis, a bacterium in the microbiome of lab-reared Anopheles mosquitoes.

Molecular and biochemical parasitology

Avec: Melanie J Shears , Sean C Murphy

Efficient infection of non-human primates with purified, cryopreserved Plasmodium knowlesi sporozoites.

Malaria journal

Avec: Sumana Chakravarty , Melanie J Shears , Eric R James , Urvashi Rai , Natasha Kc , Solomon Conteh , Lynn E Lambert , Patrick E Duffy , Sean C Murphy , Stephen L Hoffman

Preliminary studies on the immunogenicity of a prime-and-trap malaria vaccine in nonhuman primates.

Vaccine

Avec: Melanie J Shears , Felicia N Watson , Brad C Stone , Irene Cruz Talavera , Chaitra Parthiban , Jokichi Matsubara , Natasha Kc , B Kim Lee Sim , Stephen L Hoffman , Sean C Murphy

Identification of the drug/metabolite transporter 1 as a marker of quinine resistance in a NF54×Cam3.II

bioRxiv : the preprint server for biology

Avec: Mariko Kanai , Sachel Mok , Tomas Yeo , Melanie J Shears , Leila S Ross , Jin H Jeon , Sunil Narwal , Meseret T Haile , Abhai K Tripathi , Godfree Mlambo , Jonathan Kim , Eva Gil-Iturbe , John Okombo , Kate J Fairhurst , Talia Bloxham , Jessica L Bridgford , Tanaya Sheth , Kurt E Ward , Heekuk Park , Felix D Rozenberg , Matthias Quick , Filippo Mancia , Marcus C S Lee , Jennifer L Small-Saunders , Anne-Catrin Uhlemann , Photini Sinnis , David A Fidock

Proteomic Analysis of

Journal of proteome research

Avec: Melanie J Shears , Raja Sekhar Nirujogi , Kristian E Swearingen , Santosh Renuse , Satish Mishra , Panga Jaipal Reddy , Robert L Moritz , Akhilesh Pandey , Photini Sinnis

Plasmodium knowlesi in pig-tailed macaques: a potential new model for malaria vaccine research.

Malaria journal

Avec: Melanie J Shears , Rebekah A Reynolds , Caroline J Duncombe , Felicia N Watson , Weston J Staubus , Chris Chavtur , Annette M Seilie , Tuan M Tran , Sumana Chakravarty , Stephen L Hoffman , Sean C Murphy

Screening for lipid nanoparticles that modulate the immune activity of helper T cells towards enhanced antitumour activity.

Nature biomedical engineering

Avec: Yining Zhu , Jingyao Ma , Ruochen Shen , Jinghan Lin , Shuyi Li , Xiaoya Lu , Jessica L Stelzel , Jiayuan Kong , Leonardo Cheng , Ivan Vuong , Zhi-Cheng Yao , Christine Wei , Nicole M Korinetz , Wu Han Toh , Joseph Choy , Rebekah A Reynolds , Melanie J Shears , Won June Cho , Natalie K Livingston , Gregory P Howard , Yizong Hu , Stephany Y Tzeng , Donald J Zack , Jordan J Green , Lei Zheng , Joshua C Doloff , Jonathan P Schneck , Sashank K Reddy , Sean C Murphy , Hai-Quan Mao

Réseau de co-auteurs

Sean C Murphy 8 collaborations

Felicia N Watson 4 collaborations

Stephen L Hoffman 4 collaborations

Photini Sinnis 3 collaborations

Sumana Chakravarty 3 collaborations

Rebekah A Reynolds 3 collaborations

Jennifer L Small-Saunders 2 collaborations

Godfree Mlambo 2 collaborations

David A Fidock 2 collaborations

Caroline J Duncombe 2 collaborations

Anya C Kalata 2 collaborations

B Kim Lee Sim 2 collaborations

Chaitra Parthiban 2 collaborations

Brad C Stone 2 collaborations

Irene Cruz Talavera 2 collaborations

Jokichi Matsubara 2 collaborations

Natasha Kc 2 collaborations

Kyle Jarrod McLean 1 collaboration

Judith Straimer 1 collaboration

Christine S Hopp 1 collaboration

Joel Vega-Rodriguez 1 collaboration

Sachie Kanatani 1 collaboration

Abhai Tripathi 1 collaboration

Peter C Dumoulin 1 collaboration

Chantal T Harris 1 collaboration

Xinran Tong 1 collaboration

Johan Ankarklev 1 collaboration

Björn F C Kafsack 1 collaboration

Ethan Conrad 1 collaboration

Moriya Tsuji 1 collaboration

Zachary MacMillen 1 collaboration

Kiara Hatzakis 1 collaboration

Adrian Simpson 1 collaboration

Felicia Watson 1 collaboration

Jesse H Erasmus 1 collaboration

Amit P Khandhar 1 collaboration

Brandon Wilder 1 collaboration

Steven G Reed 1 collaboration

James W Davie 1 collaboration

Marion Avril 1 collaboration

Naveen Yadav 1 collaboration

Zachary P Billman 1 collaboration

Kevin Zhou 1 collaboration

Tayla M Olsen 1 collaboration

Annette Mariko Seilie 1 collaboration

Eric R James 1 collaboration

Urvashi Rai 1 collaboration

Solomon Conteh 1 collaboration

Lynn E Lambert 1 collaboration

Patrick E Duffy 1 collaboration

Mariko Kanai 1 collaboration

Sachel Mok 1 collaboration

Tomas Yeo 1 collaboration

Leila S Ross 1 collaboration

Jin H Jeon 1 collaboration

Sunil Narwal 1 collaboration

Meseret T Haile 1 collaboration

Abhai K Tripathi 1 collaboration

Jonathan Kim 1 collaboration

Eva Gil-Iturbe 1 collaboration

John Okombo 1 collaboration

Kate J Fairhurst 1 collaboration

Talia Bloxham 1 collaboration

Jessica L Bridgford 1 collaboration

Tanaya Sheth 1 collaboration

Kurt E Ward 1 collaboration

Heekuk Park 1 collaboration

Felix D Rozenberg 1 collaboration

Matthias Quick 1 collaboration

Filippo Mancia 1 collaboration

Marcus C S Lee 1 collaboration

Anne-Catrin Uhlemann 1 collaboration

Raja Sekhar Nirujogi 1 collaboration

Kristian E Swearingen 1 collaboration

Santosh Renuse 1 collaboration

Satish Mishra 1 collaboration

Panga Jaipal Reddy 1 collaboration

Robert L Moritz 1 collaboration

Akhilesh Pandey 1 collaboration

Weston J Staubus 1 collaboration

Chris Chavtur 1 collaboration

Annette M Seilie 1 collaboration

Tuan M Tran 1 collaboration

Yining Zhu 1 collaboration

Jingyao Ma 1 collaboration

Ruochen Shen 1 collaboration

Jinghan Lin 1 collaboration

Shuyi Li 1 collaboration

Xiaoya Lu 1 collaboration

Jessica L Stelzel 1 collaboration

Jiayuan Kong 1 collaboration

Leonardo Cheng 1 collaboration

Ivan Vuong 1 collaboration

Zhi-Cheng Yao 1 collaboration

Christine Wei 1 collaboration

Nicole M Korinetz 1 collaboration

Wu Han Toh 1 collaboration

Joseph Choy 1 collaboration

Won June Cho 1 collaboration

Natalie K Livingston 1 collaboration

Gregory P Howard 1 collaboration

Yizong Hu 1 collaboration

Stephany Y Tzeng 1 collaboration

Donald J Zack 1 collaboration

Jordan J Green 1 collaboration

Lei Zheng 1 collaboration

Joshua C Doloff 1 collaboration

Jonathan P Schneck 1 collaboration

Sashank K Reddy 1 collaboration

Hai-Quan Mao 1 collaboration