Nikolai Mischerikow

Affiliations

Boehringer Ingelheim RCV GmbH & Co. KG, Dr. Boehringer Gasse 5-11, A-1121 Vienna, Austria.

Publications (6)

Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRAS

Journal of medicinal chemistry

Avec: Joachim Bröker , Alex G Waterson , Chris Smethurst , Dirk Kessler , Jark Böttcher , Moriz Mayer , Gerhard Gmaschitz , Jason Phan , Andrew Little , Jason R Abbott , Qi Sun , Michael Gmachl , Dorothea Rudolph , Heribert Arnhof , Klaus Rumpel , Fabio Savarese , Thomas Gerstberger , Matthias Treu , Lorenz Herdeis , Tobias Wunberg , Andreas Gollner , Harald Weinstabl , Andreas Mantoulidis , Oliver Krämer , Darryl B McConnell , Stephen W Fesik

Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor

Journal of medicinal chemistry

Avec: Harald Weinstabl , Matthias Treu , Joerg Rinnenthal , Stephan K Zahn , Peter Ettmayer , Gerd Bader , Georg Dahmann , Dirk Kessler , Klaus Rumpel , Fabio Savarese , Thomas Gerstberger , Moriz Mayer , Andreas Zoephel , Renate Schnitzer , Wolfgang Sommergruber , Paola Martinelli , Heribert Arnhof , Biljana Peric-Simov , Karin S Hofbauer , Géraldine Garavel , Yvonne Scherbantin , Sophie Mitzner , Thomas N Fett , Guido Scholz , Jens Bruchhaus , Michelle Burkard , Roland Kousek , Tuncay Ciftci , Bernadette Sharps , Andreas Schrenk , Christoph Harrer , Daniela Haering , Bernhard Wolkerstorfer , Xuechun Zhang , Xiaobing Lv , Alicia Du , Dongyang Li , Yali Li , Jens Quant , Mark Pearson , Darryl B McConnell

Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3.

Nature chemical biology

Avec: Jark Böttcher , David Dilworth , Ulrich Reiser , Ralph A Neumüller , Michael Schleicher , Mark Petronczki , Markus Zeeb , Abdellah Allali-Hassani , Magdalena M Szewczyk , Fengling Li , Steven Kennedy , Masoud Vedadi , Dalia Barsyte-Lovejoy , Peter J Brown , Kilian V M Huber , Catherine M Rogers , Carrow I Wells , Oleg Fedorov , Klaus Rumpel , Andreas Zoephel , Moriz Mayer , Tobias Wunberg , Dietrich Böse , Stephan Zahn , Heribert Arnhof , Helmut Berger , Christoph Reiser , Alexandra Hörmann , Teresa Krammer , Maja Corcokovic , Bernadette Sharps , Sandra Winkler , Daniela Häring , Xiao-Ling Cockcroft , Julian E Fuchs , Barbara Müllauer , Alexander Weiss-Puxbaum , Thomas Gerstberger , Guido Boehmelt , Christopher R Vakoc , Cheryl H Arrowsmith , Mark Pearson , Darryl B McConnell

Targeting cancer with small-molecule pan-KRAS degraders.

Science (New York, N.Y.)

Avec: Johannes Popow , William Farnaby , Andreas Gollner , Christiane Kofink , Gerhard Fischer , Melanie Wurm , David Zollman , Andre Wijaya , Carina Hasenoehrl , Polina Prokofeva , Heribert Arnhof , Silvia Arce-Solano , Sammy Bell , Georg Boeck , Emelyne Diers , Aileen B Frost , Jake Goodwin-Tindall , Jale Karolyi-Oezguer , Shakil Khan , Theresa Klawatsch , Manfred Koegl , Roland Kousek , Barbara Kratochvil , Katrin Kropatsch , Arnel A Lauber , Ross McLennan , Sabine Olt , Daniel Peter , Oliver Petermann , Vanessa Roessler , Peggy Stolt-Bergner , Patrick Strack , Eva Strauss , Nicole Trainor , Vesna Vetma , Claire Whitworth , Siying Zhong , Jens Quant , Harald Weinstabl , Bernhard Kuster , Peter Ettmayer , Alessio Ciulli

A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo.

Nature communications

Avec: Christiane Kofink , Nicole Trainor , Barbara Mair , Simon Wöhrle , Melanie Wurm , Michael J Roy , Gerd Bader , Peter Greb , Géraldine Garavel , Emelyne Diers , Ross McLennan , Claire Whitworth , Vesna Vetma , Klaus Rumpel , Maximilian Scharnweber , Julian E Fuchs , Thomas Gerstberger , Yunhai Cui , Gabriela Gremel , Paolo Chetta , Stefan Hopf , Nicole Budano , Joerg Rinnenthal , Gerhard Gmaschitz , Moriz Mayer , Manfred Koegl , Alessio Ciulli , Harald Weinstabl , William Farnaby

Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and in vivo Experiments.

ChemMedChem

Avec: Paola Martinelli , Otmar Schaaf , Andreas Mantoulidis , Laetitia J Martin , Julian E Fuchs , Gerd Bader , Andreas Gollner , Bernhard Wolkerstorfer , Catherine Rogers , Esra Balıkçı , Jesse J Lipp , Sandra Doebel , Thomas Gerstberger , Wolfgang Sommergruber , Kilian V M Huber , Jark Böttcher

Réseau de co-auteurs

Thomas Gerstberger 5 collaborations

Moriz Mayer 4 collaborations

Heribert Arnhof 4 collaborations

Klaus Rumpel 4 collaborations

Harald Weinstabl 4 collaborations

Jark Böttcher 3 collaborations

Andreas Gollner 3 collaborations

Darryl B McConnell 3 collaborations

Gerd Bader 3 collaborations

Julian E Fuchs 3 collaborations

Dirk Kessler 2 collaborations

Gerhard Gmaschitz 2 collaborations

Fabio Savarese 2 collaborations

Matthias Treu 2 collaborations

Tobias Wunberg 2 collaborations

Andreas Mantoulidis 2 collaborations

Joerg Rinnenthal 2 collaborations

Peter Ettmayer 2 collaborations

Andreas Zoephel 2 collaborations

Wolfgang Sommergruber 2 collaborations

Paola Martinelli 2 collaborations

Géraldine Garavel 2 collaborations

Roland Kousek 2 collaborations

Bernadette Sharps 2 collaborations

Bernhard Wolkerstorfer 2 collaborations

Jens Quant 2 collaborations

Mark Pearson 2 collaborations

Kilian V M Huber 2 collaborations

William Farnaby 2 collaborations

Christiane Kofink 2 collaborations

Melanie Wurm 2 collaborations

Emelyne Diers 2 collaborations

Manfred Koegl 2 collaborations

Ross McLennan 2 collaborations

Nicole Trainor 2 collaborations

Vesna Vetma 2 collaborations

Claire Whitworth 2 collaborations

Alessio Ciulli 2 collaborations

Joachim Bröker 1 collaboration

Alex G Waterson 1 collaboration

Chris Smethurst 1 collaboration

Jason Phan 1 collaboration

Andrew Little 1 collaboration

Jason R Abbott 1 collaboration

Qi Sun 1 collaboration

Michael Gmachl 1 collaboration

Dorothea Rudolph 1 collaboration

Lorenz Herdeis 1 collaboration

Oliver Krämer 1 collaboration

Stephen W Fesik 1 collaboration

Stephan K Zahn 1 collaboration

Georg Dahmann 1 collaboration

Renate Schnitzer 1 collaboration

Biljana Peric-Simov 1 collaboration

Karin S Hofbauer 1 collaboration

Yvonne Scherbantin 1 collaboration

Sophie Mitzner 1 collaboration

Thomas N Fett 1 collaboration

Guido Scholz 1 collaboration

Jens Bruchhaus 1 collaboration

Michelle Burkard 1 collaboration

Tuncay Ciftci 1 collaboration

Andreas Schrenk 1 collaboration

Christoph Harrer 1 collaboration

Daniela Haering 1 collaboration

Xuechun Zhang 1 collaboration

Xiaobing Lv 1 collaboration

Alicia Du 1 collaboration

Dongyang Li 1 collaboration

Yali Li 1 collaboration

David Dilworth 1 collaboration

Ulrich Reiser 1 collaboration

Ralph A Neumüller 1 collaboration

Michael Schleicher 1 collaboration

Mark Petronczki 1 collaboration

Markus Zeeb 1 collaboration

Abdellah Allali-Hassani 1 collaboration

Magdalena M Szewczyk 1 collaboration

Fengling Li 1 collaboration

Steven Kennedy 1 collaboration

Masoud Vedadi 1 collaboration

Dalia Barsyte-Lovejoy 1 collaboration

Peter J Brown 1 collaboration

Catherine M Rogers 1 collaboration

Carrow I Wells 1 collaboration

Oleg Fedorov 1 collaboration

Dietrich Böse 1 collaboration

Stephan Zahn 1 collaboration

Helmut Berger 1 collaboration

Christoph Reiser 1 collaboration

Alexandra Hörmann 1 collaboration

Teresa Krammer 1 collaboration

Maja Corcokovic 1 collaboration

Sandra Winkler 1 collaboration

Daniela Häring 1 collaboration

Xiao-Ling Cockcroft 1 collaboration

Barbara Müllauer 1 collaboration

Alexander Weiss-Puxbaum 1 collaboration

Guido Boehmelt 1 collaboration

Christopher R Vakoc 1 collaboration

Cheryl H Arrowsmith 1 collaboration

Johannes Popow 1 collaboration

Gerhard Fischer 1 collaboration

David Zollman 1 collaboration

Andre Wijaya 1 collaboration

Carina Hasenoehrl 1 collaboration

Polina Prokofeva 1 collaboration

Silvia Arce-Solano 1 collaboration

Sammy Bell 1 collaboration

Georg Boeck 1 collaboration

Aileen B Frost 1 collaboration

Jake Goodwin-Tindall 1 collaboration

Jale Karolyi-Oezguer 1 collaboration

Shakil Khan 1 collaboration

Theresa Klawatsch 1 collaboration

Barbara Kratochvil 1 collaboration

Katrin Kropatsch 1 collaboration

Arnel A Lauber 1 collaboration

Sabine Olt 1 collaboration

Daniel Peter 1 collaboration

Oliver Petermann 1 collaboration

Vanessa Roessler 1 collaboration

Peggy Stolt-Bergner 1 collaboration

Patrick Strack 1 collaboration

Eva Strauss 1 collaboration

Siying Zhong 1 collaboration

Bernhard Kuster 1 collaboration

Barbara Mair 1 collaboration

Simon Wöhrle 1 collaboration

Michael J Roy 1 collaboration

Peter Greb 1 collaboration

Maximilian Scharnweber 1 collaboration

Yunhai Cui 1 collaboration

Gabriela Gremel 1 collaboration

Paolo Chetta 1 collaboration

Stefan Hopf 1 collaboration

Nicole Budano 1 collaboration

Otmar Schaaf 1 collaboration

Laetitia J Martin 1 collaboration

Catherine Rogers 1 collaboration

Esra Balıkçı 1 collaboration

Jesse J Lipp 1 collaboration

Sandra Doebel 1 collaboration