SEQing to find hidden medulloblastoma cells.

Cerebellar Neoplasms / genetics Child Humans Medulloblastoma / genetics Neoplasm, Residual Prognosis

Journal

Cancer cell
ISSN: 1878-3686
Titre abrégé: Cancer Cell
Pays: United States
ID NLM: 101130617

Informations de publication

Date de publication:
08 11 2021
Historique:
pubmed: 23 10 2021
medline: 28 12 2021
entrez: 22 10 2021
Statut: ppublish

Résumé

Minimal residual disease (MRD) assessment has revolutionized the clinical management of pediatric leukemias but has remained challenging to implement in pediatric brain tumors. In this issue of Cancer Cell, Liu et al. describe an approach to measuring MRD in pediatric medulloblastoma through the use of cell-free DNA in cerebrospinal fluid, with important prognostic implications.

Identifiants

DOI: 10.1016/j.ccell.2021.09.014 PMID: 34678149
pubmed: 34678149
pii: S1535-6108(21)00503-1
doi: 10.1016/j.ccell.2021.09.014
pii:
doi:

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

1452-1454

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Auteurs

John R Prensner (JR)

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA.

Scott L Pomeroy (SL)

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Neurology, Boston Children's Hospital, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA. Electronic address: scott.pomeroy@childrens.harvard.edu.

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Classifications MeSH

Recherchemedicale.com › Maladies du système nerveux › Tumeurs du système nerveux › Tumeurs du système nerveux central › Tumeurs du cerveau › Tumeurs sous-tentorielles › Tumeurs du cervelet › SEQing to find hidden medulloblastoma cells.
Recherchemedicale.com › Personnes › Tranches d'âge › Enfant › SEQing to find hidden medulloblastoma cells.
Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › SEQing to find hidden medulloblastoma cells.
Recherchemedicale.com › Tumeurs › Tumeurs par type histologique › Tumeurs du tissu nerveux › Tumeurs neuroectodermiques › Tumeurs neuroépitheliales › Tumeurs neuroectodermiques primitives › Médulloblastome › SEQing to find hidden medulloblastoma cells.
Recherchemedicale.com › États, signes et symptômes pathologiques › Processus pathologiques › Processus néoplasiques › Maladie résiduelle › SEQing to find hidden medulloblastoma cells.
Recherchemedicale.com › Diagnostic › Pronostic › SEQing to find hidden medulloblastoma cells.