Titre : Vaccins contre le SIDA

Vaccins contre le SIDA : Questions médicales fréquentes

Questions fréquentes et termes MeSH associés

Diagnostic 2

#1

Comment évaluer l'efficacité d'un vaccin contre le SIDA ?

L'efficacité est évaluée par des essais cliniques mesurant la réduction des infections.
Vaccins SIDA Essais cliniques
#2

Quels tests sont utilisés pour diagnostiquer le VIH ?

Les tests sérologiques et les tests d'acide nucléique détectent le VIH dans le sang.
VIH Tests de dépistage Diagnostic

Symptômes 2

#1

Quels sont les symptômes du VIH/SIDA ?

Les symptômes incluent fièvre, fatigue, éruptions cutanées et infections opportunistes.
SIDA Symptômes Infections opportunistes
#2

Le vaccin peut-il provoquer des symptômes ?

Des effets secondaires légers comme douleur au site d'injection peuvent survenir.
Vaccins Effets secondaires SIDA

Prévention 2

#1

Comment les vaccins contribuent-ils à la prévention du SIDA ?

Ils stimulent le système immunitaire pour prévenir l'infection par le VIH.
Prévention Vaccins SIDA
#2

Quelles autres méthodes préviennent le VIH ?

L'utilisation de préservatifs et la prophylaxie pré-exposition (PrEP) sont efficaces.
Prévention VIH PrEP

Traitements 2

#1

Les vaccins remplacent-ils les traitements antirétroviraux ?

Non, les vaccins complètent les traitements, mais ne les remplacent pas.
Traitements antirétroviraux Vaccins SIDA
#2

Quels traitements sont disponibles pour le VIH ?

Les traitements incluent les antirétroviraux qui contrôlent la charge virale.
VIH Antirétroviraux Traitements

Complications 2

#1

Quelles complications peuvent survenir sans vaccin ?

Sans vaccin, le risque d'infections opportunistes et de maladies graves augmente.
Complications SIDA Infections opportunistes
#2

Les vaccins peuvent-ils causer des complications ?

Des complications graves sont rares, mais des réactions allergiques peuvent survenir.
Vaccins Complications Réactions allergiques

Facteurs de risque 2

#1

Quels sont les facteurs de risque pour le VIH ?

Les rapports non protégés, le partage de seringues et les antécédents d'infections sont des risques.
Facteurs de risque VIH Comportements à risque
#2

Les vaccins réduisent-ils les facteurs de risque ?

Oui, en prévenant l'infection, les vaccins diminuent les comportements à risque associés.
Vaccins Prévention Facteurs de risque
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Dr Olivier Menir

Contenu validé par Dr Olivier Menir

Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale


Validation scientifique effectuée le 27/12/2024

Contenu vérifié selon les dernières recommandations médicales

Auteurs principaux

Jianzhou Yang

3 publications dans cette catégorie

Affiliations :
  • Department of Preventive Medicine, Changzhi Medical College, Changzhi, China.

Xiangjun Zhang

3 publications dans cette catégorie

Affiliations :
  • Department of Public Health, University of Tennessee, Knoxville, TN, United States.

Xiaojie Huang

3 publications dans cette catégorie

Affiliations :
  • Beijing Youan Hospital, Capital Medical University, Beijing, China.

Maohe Yu

3 publications dans cette catégorie

Affiliations :
  • Tianjin Centers for Disease Control and Prevention, Tianjin, China.

Guanghua Lan

3 publications dans cette catégorie

Affiliations :
  • Guangxi Center for Disease Prevention and Control, Nanning, China.

Ying Qiao

3 publications dans cette catégorie

Affiliations :
  • The Second Hospital of Huhhot, Huhhot, China.

Junjie Xu

3 publications dans cette catégorie

Affiliations :
  • Clinical Research Academy, Peking University Shenzhen Hospital, Peking University, Shenzhen, China.

Pepijn van Empelen

2 publications dans cette catégorie

Affiliations :
  • Netherlands Organization for Applied Scientific Research (TNO), Expertise Group Child Health, Leiden, Netherlands.

Mohit Chawla

2 publications dans cette catégorie

Affiliations :
  • Physical Sciences and Engineering Division, Kaust Catalysis Center, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.

Chonticha Suwattanasophon

2 publications dans cette catégorie

Affiliations :
  • Department of Biochemistry, Faculty of Science, Kasetsart University, Bangkok, Thailand.

Kiattawee Choowongkomon

2 publications dans cette catégorie

Affiliations :
  • Department of Biochemistry, Faculty of Science, Kasetsart University, Bangkok, Thailand.

Abdul Rajjak Shaikh

2 publications dans cette catégorie

Affiliations :
  • Department of Research and Innovation, STEMskills Research and Education Lab Private Limited, Faridabad, Haryana, India.

Luigi Cavallo

2 publications dans cette catégorie

Affiliations :
  • Physical Sciences and Engineering Division, Kaust Catalysis Center, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.

Subhra Chakraborty

2 publications dans cette catégorie

Affiliations :
  • Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: schakr11@jhu.edu.

Yan Yao

2 publications dans cette catégorie

Affiliations :
  • Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, China.

Ruiyu Chai

2 publications dans cette catégorie

Affiliations :
  • Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, China.

Geng-Feng Fu

2 publications dans cette catégorie

Affiliations :
  • Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.

Qidi Zhou

2 publications dans cette catégorie

Affiliations :
  • Department of Emergency Medicine, Shenzhen Hospital, Peking University, Shenzhen, China.

Shuyue Li

2 publications dans cette catégorie

Affiliations :
  • Changchun Maternity Hospital, Changchun, China.

Yulia Gendler

2 publications dans cette catégorie

Affiliations :
  • The Department of Nursing, School of Health Sciences, Ariel University, Ariel 40700, Israel.

Sources (10000 au total)

Overcoming Vaccine Hesitancy for Future COVID-19 and HIV Vaccines: Lessons from Measles and HPV Vaccines.

The discovery of vaccines significantly reduced morbidity and mortality of infectious diseases and led to the elimination and eradication of some. Development of safe and effective vaccines is a criti... We conducted a narrative review of studies on interventions to address measles and human papillomavirus vaccine hesitancy. We discussed how lessons learned from these studies could be applied towards ... We found that there are several successful approaches to improving vaccine acceptance. Interventions should be context specific and build on the challenges highlighted in various settings.... Strategies could be used alone or in combination with others. The most successful interventions directly targeted the population for vaccination. Use of financial incentives could be a potential tool ...

HIV-1 therapeutic vaccines in clinical development to intensify or replace antiretroviral therapy: the promising results of the Tat vaccine.

Upon the introduction of the combination antiretroviral therapy (cART), HIV infection has become a chronic disease. However, cART is unable to eradicate the virus and fails to restore the CD4 counts i... Here, we briefly discuss the obstacles to the development and evaluation of the efficacy of therapeutic vaccines and review recent approaches evaluated in clinical trials.... Although vaccines were generally safe and immunogenic, evidence of efficacy was negligible or marginal in most trials. A notable exception is the therapeutic Tat vaccine approach showing promising res...

COVID-19 vaccine immunogenicity in people with HIV.

Many vaccines require higher/additional doses or adjuvants to provide adequate protection for people with HIV (PWH). Our objective was to compare COVID-19 vaccine immunogenicity in PWH to HIV-negative... In a Canadian multi-center prospective, observational cohort of PWH receiving at least two COVID-19 vaccinations, we measured vaccine-induced immunity at 3 and 6 months post 2nd and 1-month post 3rd d... The primary outcome was the percentage of PWH mounting vaccine-induced immunity [co-positivity for anti-IgG against SARS-CoV2 Spike(S) and receptor-binding domain proteins] 6 months post 2nd dose. Uni... Data from 294 PWH and 267 controls were analyzed. Immunogenicity was achieved in over 90% at each time point in both groups. The proportions of participants achieving comparable anti-receptor-binding ... Vaccine-induced IgG was elicited in the vast majority of PWH and was overall similar between groups. A slightly lower proportion of PWH vs. controls maintained vaccine-induced anti-S IgG immunity 6 mo...

Baseline host determinants of robust human HIV-1 vaccine-induced immune responses: A meta-analysis of 26 vaccine regimens.

The identification of baseline host determinants that associate with robust HIV-1 vaccine-induced immune responses could aid HIV-1 vaccine development. We aimed to assess both the collective and relat... This was a meta-analysis of individual participant data, with studies chosen based on participant-level (vs. study-level summary) data availability within the HIV-1 Vaccine Trials Network. We assessed... Overall, 30.1%, 50.5%, 36.2%, and 13.9% of participants were categorized as High responders for gp120 IgG, gp140 IgG, gp41 IgG, and Env-specific CD4+ T-cell vaccine-induced responses, respectively. Wh... The identified features should be studied further in pursuit of intervention strategies to improve vaccine responses and may be adjusted for in analyses of immune response data to enhance statistical ... National Institute of Allergy and Infectious Diseases (UM1AI068635 to YH, UM1AI068614 to GDT, UM1AI068618 to MJM, and UM1 AI069511 to MCK), the Duke CFAR P30 AI064518 to GDT, and National Institute of...