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Acides nucléiques, nucléotides et nucléosides
Nucléosides
Nucléosides pyrimidiques
Pentostatine
Pentostatine : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Marqueurs tumoraux
Lymphome
Suivi médical
Traitement du cancer
Symptômes
5
Effets secondaires
Nausées
Symptômes neurologiques
Maux de tête
Réaction allergique
Éruption cutanée
Infections
Immunosuppression
Saignements
Douleurs thoraciques
Prévention
5
Prévention des effets secondaires
Hydratation
Précautions médicales
Allergies
Vaccination
Prévention des infections
Nutrition
Système immunitaire
Traitements
5
Administration intraveineuse
Traitement du cancer
Chimiothérapie
Traitement combiné
Durée du traitement
Lymphome
Ajustement de dose
Effets secondaires
Hospitalisation
Traitement du cancer
Complications
5
Problèmes cardiaques
Risque
Tests sanguins
Surveillance médicale
Facteurs de risque
5
Facteurs de risque
Maladies auto-immunes
Antécédents familiaux
Cancer
Conditions médicales
Risque
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"name": "Comment la pentostatine est-elle diagnostiquée ?",
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{
"@type": "Question",
"name": "Quels tests précèdent l'utilisation de pentostatine ?",
"position": 2,
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"@type": "Question",
"name": "La pentostatine est-elle utilisée pour tous les cancers ?",
"position": 3,
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"@type": "Question",
"name": "Quels marqueurs tumoraux sont surveillés ?",
"position": 4,
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"@type": "Question",
"name": "La pentostatine nécessite-t-elle un suivi régulier ?",
"position": 5,
"acceptedAnswer": {
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{
"@type": "Question",
"name": "Quels sont les effets secondaires de la pentostatine ?",
"position": 6,
"acceptedAnswer": {
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"text": "Les effets secondaires incluent fatigue, nausées, et suppression de la moelle osseuse."
}
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{
"@type": "Question",
"name": "La pentostatine cause-t-elle des symptômes neurologiques ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes neurologiques comme des maux de tête peuvent survenir, bien que rares."
}
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{
"@type": "Question",
"name": "Quels symptômes indiquent une réaction allergique ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des démangeaisons, éruptions cutanées ou difficultés respiratoires peuvent indiquer une allergie."
}
},
{
"@type": "Question",
"name": "La pentostatine peut-elle provoquer des infections ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut augmenter le risque d'infections en raison de la suppression immunitaire."
}
},
{
"@type": "Question",
"name": "Quels symptômes nécessitent une consultation urgente ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme des saignements inhabituels ou des douleurs thoraciques doivent être évalués."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les effets secondaires de la pentostatine ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines mesures comme une bonne hydratation et des médicaments anti-nauséeux peuvent aider."
}
},
{
"@type": "Question",
"name": "Y a-t-il des précautions à prendre avant le traitement ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, informer le médecin des allergies et des médicaments en cours est crucial."
}
},
{
"@type": "Question",
"name": "Comment minimiser le risque d'infection ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les foules et pratiquer une bonne hygiène peut réduire le risque d'infections."
}
},
{
"@type": "Question",
"name": "Des vaccinations sont-elles recommandées ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des vaccinations peuvent être recommandées avant le traitement pour prévenir les infections."
}
},
{
"@type": "Question",
"name": "La nutrition joue-t-elle un rôle dans le traitement ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation équilibrée peut soutenir le système immunitaire pendant le traitement."
}
},
{
"@type": "Question",
"name": "Comment la pentostatine est-elle administrée ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle est généralement administrée par voie intraveineuse sous supervision médicale."
}
},
{
"@type": "Question",
"name": "La pentostatine est-elle utilisée seule ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut être utilisée seule ou en combinaison avec d'autres agents chimiothérapeutiques."
}
},
{
"@type": "Question",
"name": "Quelle est la durée du traitement par pentostatine ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La durée varie selon le type de cancer, mais peut durer plusieurs mois."
}
},
{
"@type": "Question",
"name": "Des ajustements de dose sont-ils nécessaires ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des ajustements peuvent être nécessaires en fonction de la tolérance et des effets."
}
},
{
"@type": "Question",
"name": "La pentostatine nécessite-t-elle une hospitalisation ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Pas toujours, mais une hospitalisation peut être nécessaire pour des traitements intensifs."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles de la pentostatine ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent infections, anémie, et problèmes hépatiques ou rénaux."
}
},
{
"@type": "Question",
"name": "Comment gérer une infection liée à la pentostatine ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un traitement antibiotique peut être nécessaire pour gérer les infections survenant."
}
},
{
"@type": "Question",
"name": "La pentostatine peut-elle causer des problèmes cardiaques ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des problèmes cardiaques sont rares, mais peuvent survenir chez certains patients à risque."
}
},
{
"@type": "Question",
"name": "Quels tests pour surveiller les complications ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests sanguins réguliers et des examens cliniques sont nécessaires pour surveiller."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles réversibles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être réversibles avec un traitement approprié et rapide."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour l'utilisation de pentostatine ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents de maladies auto-immunes et d'infections augmentent les risques."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il l'utilisation de pentostatine ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients plus âgés peuvent avoir un risque accru d'effets secondaires."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de cancers peuvent augmenter le risque de développer des cancers."
}
},
{
"@type": "Question",
"name": "Le tabagisme est-il un facteur de risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme est un facteur de risque connu pour plusieurs types de cancers."
}
},
{
"@type": "Question",
"name": "Des conditions médicales préexistantes augmentent-elles les risques ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des conditions comme le diabète ou des maladies cardiaques peuvent augmenter les risques."
}
}
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}
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}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 05/11/2024
Contenu vérifié selon les dernières recommandations médicales
1 publication dans cette catégorie
Affiliations :
College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Key Laboratory for Agricultural Biochemistry and Biotransformation of Hunan Provincial University, Changsha 410128, Hunan, China.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Key Laboratory for Agricultural Biochemistry and Biotransformation of Hunan Provincial University, Changsha 410128, Hunan, China.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Key Laboratory for Agricultural Biochemistry and Biotransformation of Hunan Provincial University, Changsha 410128, Hunan, China.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Key Laboratory for Agricultural Biochemistry and Biotransformation of Hunan Provincial University, Changsha 410128, Hunan, China.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Key Laboratory for Agricultural Biochemistry and Biotransformation of Hunan Provincial University, Changsha 410128, Hunan, China.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Key Laboratory for Agricultural Biochemistry and Biotransformation of Hunan Provincial University, Changsha 410128, Hunan, China.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Key Laboratory for Agricultural Biochemistry and Biotransformation of Hunan Provincial University, Changsha 410128, Hunan, China.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
Department of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
Department of Microbiology and Parasitology, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
Laboratory of Parasitology and Parasitic Diseases, Instituto Federal Farroupilha (IFFar), campus Frederico Westphalen, Brazil.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
Department of Microbiology and Parasitology, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
Department of Microbiology and Parasitology, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
Department of Microbiology and Parasitology, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
Veterinary Pathology Laboratory, Instituto Federal Catarinense (IFC), Concórdia, SC, Brazil.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
Veterinary Pathology Laboratory, Instituto Federal Catarinense (IFC), Concórdia, SC, Brazil.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
Department of Animal Science, Universidade do Estado de Santa Catarina (UDESC), Chapecó, SC, Brazil.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
Department of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil; Department of Animal Science, Universidade do Estado de Santa Catarina (UDESC), Chapecó, SC, Brazil. Electronic address: aleksandro_ss@yahoo.com.br.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
Department of Pharmaceutical and Administrative Sciences, College of Pharmacy and Health Sciences, Drake University, Des Moines, IA, 50311, USA.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
Department of Microbiology and Immunology, College of Osteopathic Medicine, Des Moines University, Des Moines, IA, 50312, USA.
Publications dans "Pentostatine" :
1 publication dans cette catégorie
Affiliations :
Microbiotix Inc., Worcester, MA, 01605, USA.
Publications dans "Pentostatine" :
Our first patient was a 42-year-old healthy Chinese man with moderately severe psoriasis, not adequately controlled with potent topical steroids and vitamin D analogs. His pre-immunosuppressant work-u...
Erythromelalgia is a rare syndrome characterised by recurrent erythema, heat and burning pain in the extremities. There are two types: primary (genetic) and secondary (toxic, drug-related or associate...
Drug-induced gingival overgrowth (DIGO) is an undesirable effect resulting from the therapy of one of the three groups of drugs: phenytoin, calcium channel blockers, and cyclosporine A (CsA). It is ca...
Drug development in traumatic brain injury (TBI) has been impeded by the complexity and heterogeneity of the disease pathology, as well as limited understanding of the secondary injury cascade that fo...
The clinical use of cyclosporin A (CsA) has led to significant advances and achievements in the field of transplantation and immune diseases. However, the nephrotoxicity of CsA is a major concern in c...
To compare the efficacy of topical 0.05% cyclosporine A (CsA) and 0.1% topical cyclosporine A (CsA) over a 6-month period following pterygium surgery, specifically evaluating their effects on postoper...
This clinical study enrolled 245 patients with pterygium who underwent surgery using the conjunctival autograft technique with mitomycin C (MMC) were enrolled. Participants were divided into three gro...
The mean age of the patients was 63.22 ± 9.39 years, with 53.3% male and 46.7% female. The three groups were similar in terms of demographic characteristics and pterygium size. Inflammation in surgica...
This study showed that there was no difference between the efficacy of 6 month topical 0.05% CsA and 0.1% CsA application after pterygium surgery with the conjunctival autograft technique with MMC on ...
A novel ratiometric fluorescent sensor was fabricated for the fast and facile determination of cyclosporine A (CsA). Due to the narrow therapeutic index of CsA, its desired therapeutic effects are evi...
Cyclosporine is widely used for immunosuppressive treatment of various systematic and local autoimmune diseases. Breastfeeding is conventionally contraindicated when treating with cyclosporine due to ...
A 32-year-old dichorionic twin-pregnancy woman had nephrotic syndrome with renal biopsy confirmed type V lupus nephritis for over five years. She was treated only with prednisone 10 mg a day before pr...
In this case, cyclosporine levels in breast milk were low at all times of the day. The growth and development of both infants were normal at three months postpartum. Thus, breastfeeding may still be a...
Cyclosporin A (CsA) is a hydrophobic drug widely used as an immunosuppressant and anti-rejection drug in solid organ transplantation. On the market, there are two oral CsA formulations available conta...
CsA-NSs were prepared using a wet bead milling method. Particle size, morphology and crystallinity state of CsA-NSs were characterized. The in vitro dissolution, the intestinal absorption properties a...
CsA-NSs with sizes of 280 nm, 522 nm and 2967 nm were prepared. The shape of CsA-NSs with smaller size was similar to that of spheres. The crystallinity of CsA in nanocrystals was reduced. The dissolu...
It is feasible to prepare CsA-NSs. The dissolution rate, gastrointestinal transport properties and the oral absorption of CsA-NSs were promoted by reducing size. Considering the cost, efficiency and e...
Survivors of immune-mediated thrombotic thrombocytopenic purpura (iTTP) are exposed to clinical relapses when a disintegrin and metalloproteinase with thrombospondin type 1 repeats, member 13 (ADAMTS1...