Zachary Madaj

Affiliations

Van Andel Research Institute, Grand Rapids, MI, USA.

Publications (23)

Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes.

Clinical epigenetics

Avec: Linn Gillberg , Andreas D Ørskov , Ammar Nasif , Hitoshi Ohtani , Zachary Madaj , Jakob W Hansen , Nicolas Rapin , Johanne B Mogensen , Minmin Liu , Inge H Dufva , Jens Lykkesfeldt , Petra Hajkova , Peter A Jones , Kirsten Grønbæk

Chromosome-specific retention of cancer-associated DNA hypermethylation following pharmacological inhibition of DNMT1.

Communications biology

Avec: Ashley K Wiseman , Rochelle L Tiedemann , Huihui Fan , Hui Shen , Zachary Madaj , Michael T McCabe , Melissa B Pappalardi , Peter A Jones

Altered Tryptophan Catabolism in Placentas From Women With Pre-eclampsia.

International journal of tryptophan research : IJTR

Avec: Sarah A Keaton , Patrick Heilman , Elena Y Bryleva , Zachary Madaj , Stanislaw Krzyzanowski , Jamie Grit , Emily S Miller , Maya Jälmby , Grigoros Kalapotharakos , Karen Racicot , Asgerally Fazleabas , Stefan R Hansson , Lena Brundin

Deficits in olfactory sensitivity in a mouse model of Parkinson's disease revealed by plethysmography of odor-evoked sniffing.

Scientific reports

Avec: Michaela E Johnson , Liza Bergkvist , Gabriela Mercado , Lucas Stetzik , Lindsay Meyerdirk , Emily Wolfrum , Zachary Madaj , Patrik Brundin , Daniel W Wesson

Developmental priming of cancer susceptibility.

bioRxiv : the preprint server for biology

Avec: Ilaria Panzeri , Luca Fagnocchi , Stefanos Apostle , Megan Tompkins , Emily Wolfrum , Zachary Madaj , Galen Hostetter , Yanqing Liu , Kristen Schaefer , Yang Chih-Hsiang , Alexis Bergsma , Anne Drougard , Erez Dror , Auteur inconnu , Darrell Chandler , Daniel Schramek , Timothy J Triche , J Andrew Pospisilik

Chronic obesity does not alter cancer survival in

bioRxiv : the preprint server for biology

Avec: Ilaria Panzeri , Zachary Madaj , Luca Fagnocchi , Stefanos Apostle , Megan Tompkins , Galen Hostetter , J Andrew Pospisilik

Long distance ski racing is associated with lower long-term incidence of depression in a population based, large-scale study.

Psychiatry research

Avec: Martina Svensson , Lena Brundin , Sophie Erhardt , Zachary Madaj , Ulf Hållmarker , Stefan James , Tomas Deierborg

Microglia affect α-synuclein cell-to-cell transfer in a mouse model of Parkinson's disease.

Molecular neurodegeneration

Avec: Sonia George , Nolwen L Rey , Trevor Tyson , Corinne Esquibel , Lindsay Meyerdirk , Emily Schulz , Steven Pierce , Amanda R Burmeister , Zachary Madaj , Jennifer A Steiner , Martha L Escobar Galvis , Lena Brundin , Patrik Brundin

Cytokines and tryptophan metabolites can predict depressive symptoms in pregnancy.

Translational psychiatry

Avec: Qiong Sha , Zach Madaj , Sarah Keaton , Martha L Escobar Galvis , LeAnn Smart , Stanislaw Krzyzanowski , Asgerally T Fazleabas , Richard Leach , Teodor T Postolache , Eric D Achtyes , Lena Brundin

LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression.

Translational neurodegeneration

Avec: Noah Lubben , Julia K Brynildsen , Connor M Webb , Howard L Li , Cheryl E G Leyns , Lakshmi Changolkar , Bin Zhang , Emily S Meymand , Mia O'Reilly , Zach Madaj , Daniella DeWeerd , Matthew J Fell , Virginia M Y Lee , Dani S Bassett , Michael X Henderson

Ketolysis drives CD8

Immunity

Avec: Katarzyna M Luda , Joseph Longo , Susan M Kitchen-Goosen , Lauren R Duimstra , Eric H Ma , McLane J Watson , Brandon M Oswald , Zhen Fu , Zachary Madaj , Ariana Kupai , Bradley M Dickson , Lisa M DeCamp , Michael S Dahabieh , Shelby E Compton , Robert Teis , Irem Kaymak , Kin H Lau , Daniel P Kelly , Patrycja Puchalska , Kelsey S Williams , Connie M Krawczyk , Dominique Lévesque , François-Michel Boisvert , Ryan D Sheldon , Scott B Rothbart , Peter A Crawford , Russell G Jones

Ductal tree ablation by local delivery of ethanol prevents tumor formation in an aggressive mouse model of breast cancer.

Breast cancer research : BCR

Avec: Elizabeth Kenyon , Jennifer J Westerhuis , Maximilian Volk , Jeremy Hix , Shatadru Chakravarty , Ethan Claucherty , Erin Zaluzec , Lisa Ramsey , Zach Madaj , Galen Hostetter , Bryn Eagleson , Erik Shapiro , Anna Moore , Lorenzo F Sempere

α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb.

Acta neuropathologica communications

Avec: Nolwen L Rey , Luc Bousset , Sonia George , Zachary Madaj , Lindsay Meyerdirk , Emily Schulz , Jennifer A Steiner , Ronald Melki , Patrik Brundin

Oocyte age and preconceptual alcohol use are highly correlated with epigenetic imprinting of a noncoding RNA (

Proceedings of the National Academy of Sciences of the United States of America

Avec: Brittany L Carpenter , Tanaka K Remba , Stacey L Thomas , Zachary Madaj , Lucy Brink , Rochelle L Tiedemann , Hein J Odendaal , Peter A Jones

Impact of Preanalytical Factors on the Measurement of Tumor Tissue Biomarkers Using Immunohistochemistry.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Avec: Aditi Bagchi , Zachary Madaj , Kelly B Engel , Ping Guan , Daniel C Rohrer , Dana R Valley , Emily Wolfrum , Kristin Feenstra , Nancy Roche , Galen Hostetter , Helen M Moore , Scott D Jewell

Use of predictive spatial modeling to reveal that primary cancers have distinct central nervous system topography patterns of brain metastasis.

Journal of neurosurgery

Avec: Josh Neman , Meredith Franklin , Zachary Madaj , Krutika Deshpande , Timothy J Triche , Gal Sadlik , John D Carmichael , Eric Chang , Cheng Yu , Ben A Strickland , Gabriel Zada

A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: H Josh Jang , Galen Hostetter , Alexander W Macfarlane , Zachary Madaj , Eric A Ross , Toshinori Hinoue , Justin R Kulchycki , Ryan S Burgos , Mahvish Tafseer , R Katherine Alpaugh , Candice L Schwebel , Rutika Kokate , Daniel M Geynisman , Matthew R Zibelman , Pooja Ghatalia , Peter W Nichols , Woonbok Chung , Jozef Madzo , Noah M Hahn , David I Quinn , Jean-Pierre J Issa , Michael J Topper , Stephen B Baylin , Hui Shen , Kerry S Campbell , Peter A Jones , Elizabeth R Plimack

Integrative transcriptome- and DNA methylation analysis of brain tissue from the temporal pole in suicide decedents and their controls.

Molecular psychiatry

Avec: Qiong Sha , Zhen Fu , Martha L Escobar Galvis , Zach Madaj , Mark D Underwood , Jennifer A Steiner , Andrew Dwork , Norman Simpson , Hanga Galfalvy , Gorazd Rozoklija , Eric D Achtyes , J John Mann , Lena Brundin

Loss of microRNA-21 leads to profound stromal remodeling and short survival in K-Ras-driven mouse models of pancreatic cancer.

International journal of cancer

Avec: Josh Schipper , Jennifer J Westerhuis , Ian Beddows , Zach Madaj , David Monsma , Galen Hostetter , Matti Kiupel , Jose R Conejo-Garcia , Lorenzo F Sempere

Loss of One Engrailed1 Allele Enhances Induced α-Synucleinopathy.

Journal of Parkinson's disease

Avec: Diptaman Chatterjee , Daniel Saiz Sanchez , Emmanuel Quansah , Nolwen L Rey , Sonia George , Katelyn Becker , Zachary Madaj , Jennifer A Steiner , Jiyan Ma , Martha L Escobar Galvis , Jeffrey H Kordower , Patrik Brundin

An extended release GLP-1 analogue increases α-synuclein accumulation in a mouse model of prodromal Parkinson's disease.

Experimental neurology

Avec: Liza Bergkvist , Michaela E Johnson , Gabriela Mercado , Jennifer A Steiner , Lindsay Meyerdirk , Emily Schulz , Zachary Madaj , Jiyan Ma , Katelyn Becker , Yazhou Li , Patrik Brundin

Co-expression network analysis of frontal cortex during the progression of Alzheimer's disease.

Cerebral cortex (New York, N.Y. : 1991)

Avec: John S Beck , Zachary Madaj , Calvin T Cheema , Betul Kara , David A Bennett , Julie A Schneider , Marcia N Gordon , Stephen D Ginsberg , Elliott J Mufson , Scott E Counts

Inhibiting the mitochondrial pyruvate carrier does not ameliorate synucleinopathy in the absence of inflammation or metabolic deficits.

Free neuropathology

Avec: Wouter Peelaerts , Liza Bergkvist , Sonia George , Michaela Johnson , Lindsay Meyerdirk , Emily Schulz , Jennifer A Steiner , Zachary Madaj , Jiyan Ma , Katelyn Becker , K Peter R Nilsson , Jerry R Colca , Patrik Brundin

Réseau de co-auteurs

Patrik Brundin 6 collaborations

Galen Hostetter 6 collaborations

Jennifer A Steiner 6 collaborations

Lena Brundin 5 collaborations

Lindsay Meyerdirk 5 collaborations

Zach Madaj 5 collaborations

Peter A Jones 4 collaborations

Sonia George 4 collaborations

Emily Schulz 4 collaborations

Martha L Escobar Galvis 4 collaborations

Liza Bergkvist 3 collaborations

Emily Wolfrum 3 collaborations

Nolwen L Rey 3 collaborations

Katelyn Becker 3 collaborations

Jiyan Ma 3 collaborations

Rochelle L Tiedemann 2 collaborations

Hui Shen 2 collaborations

Stanislaw Krzyzanowski 2 collaborations

Michaela E Johnson 2 collaborations

Gabriela Mercado 2 collaborations

Ilaria Panzeri 2 collaborations

Luca Fagnocchi 2 collaborations

Stefanos Apostle 2 collaborations

Megan Tompkins 2 collaborations

Timothy J Triche 2 collaborations

J Andrew Pospisilik 2 collaborations

Qiong Sha 2 collaborations

Eric D Achtyes 2 collaborations

Zhen Fu 2 collaborations

Jennifer J Westerhuis 2 collaborations

Lorenzo F Sempere 2 collaborations

Linn Gillberg 1 collaboration

Andreas D Ørskov 1 collaboration

Ammar Nasif 1 collaboration

Hitoshi Ohtani 1 collaboration

Jakob W Hansen 1 collaboration

Nicolas Rapin 1 collaboration

Johanne B Mogensen 1 collaboration

Minmin Liu 1 collaboration

Inge H Dufva 1 collaboration

Jens Lykkesfeldt 1 collaboration

Petra Hajkova 1 collaboration

Kirsten Grønbæk 1 collaboration

Ashley K Wiseman 1 collaboration

Huihui Fan 1 collaboration

Michael T McCabe 1 collaboration

Melissa B Pappalardi 1 collaboration

Sarah A Keaton 1 collaboration

Patrick Heilman 1 collaboration

Elena Y Bryleva 1 collaboration

Jamie Grit 1 collaboration

Emily S Miller 1 collaboration

Maya Jälmby 1 collaboration

Grigoros Kalapotharakos 1 collaboration

Karen Racicot 1 collaboration

Asgerally Fazleabas 1 collaboration

Stefan R Hansson 1 collaboration

Lucas Stetzik 1 collaboration

Daniel W Wesson 1 collaboration

Yanqing Liu 1 collaboration

Kristen Schaefer 1 collaboration

Yang Chih-Hsiang 1 collaboration

Alexis Bergsma 1 collaboration

Anne Drougard 1 collaboration

Erez Dror 1 collaboration

None None 1 collaboration

Darrell Chandler 1 collaboration

Daniel Schramek 1 collaboration

Martina Svensson 1 collaboration

Sophie Erhardt 1 collaboration

Ulf Hållmarker 1 collaboration

Stefan James 1 collaboration

Tomas Deierborg 1 collaboration

Trevor Tyson 1 collaboration

Corinne Esquibel 1 collaboration

Steven Pierce 1 collaboration

Amanda R Burmeister 1 collaboration

Sarah Keaton 1 collaboration

LeAnn Smart 1 collaboration

Asgerally T Fazleabas 1 collaboration

Richard Leach 1 collaboration

Teodor T Postolache 1 collaboration

Noah Lubben 1 collaboration

Julia K Brynildsen 1 collaboration

Connor M Webb 1 collaboration

Howard L Li 1 collaboration

Cheryl E G Leyns 1 collaboration

Lakshmi Changolkar 1 collaboration

Bin Zhang 1 collaboration

Emily S Meymand 1 collaboration

Mia O'Reilly 1 collaboration

Daniella DeWeerd 1 collaboration

Matthew J Fell 1 collaboration

Virginia M Y Lee 1 collaboration

Dani S Bassett 1 collaboration

Michael X Henderson 1 collaboration

Katarzyna M Luda 1 collaboration

Joseph Longo 1 collaboration

Susan M Kitchen-Goosen 1 collaboration

Lauren R Duimstra 1 collaboration

Eric H Ma 1 collaboration

McLane J Watson 1 collaboration

Brandon M Oswald 1 collaboration

Ariana Kupai 1 collaboration

Bradley M Dickson 1 collaboration

Lisa M DeCamp 1 collaboration

Michael S Dahabieh 1 collaboration

Shelby E Compton 1 collaboration

Robert Teis 1 collaboration

Irem Kaymak 1 collaboration

Kin H Lau 1 collaboration

Daniel P Kelly 1 collaboration

Patrycja Puchalska 1 collaboration

Kelsey S Williams 1 collaboration

Connie M Krawczyk 1 collaboration

Dominique Lévesque 1 collaboration

François-Michel Boisvert 1 collaboration

Ryan D Sheldon 1 collaboration

Scott B Rothbart 1 collaboration

Peter A Crawford 1 collaboration

Russell G Jones 1 collaboration

Elizabeth Kenyon 1 collaboration

Maximilian Volk 1 collaboration

Jeremy Hix 1 collaboration

Shatadru Chakravarty 1 collaboration

Ethan Claucherty 1 collaboration

Erin Zaluzec 1 collaboration

Lisa Ramsey 1 collaboration

Bryn Eagleson 1 collaboration

Erik Shapiro 1 collaboration

Anna Moore 1 collaboration

Luc Bousset 1 collaboration

Ronald Melki 1 collaboration

Brittany L Carpenter 1 collaboration

Tanaka K Remba 1 collaboration

Stacey L Thomas 1 collaboration

Lucy Brink 1 collaboration

Hein J Odendaal 1 collaboration

Aditi Bagchi 1 collaboration

Kelly B Engel 1 collaboration

Ping Guan 1 collaboration

Daniel C Rohrer 1 collaboration

Dana R Valley 1 collaboration

Kristin Feenstra 1 collaboration

Nancy Roche 1 collaboration

Helen M Moore 1 collaboration

Scott D Jewell 1 collaboration

Josh Neman 1 collaboration

Meredith Franklin 1 collaboration

Krutika Deshpande 1 collaboration

Gal Sadlik 1 collaboration

John D Carmichael 1 collaboration

Eric Chang 1 collaboration

Cheng Yu 1 collaboration

Ben A Strickland 1 collaboration

Gabriel Zada 1 collaboration

H Josh Jang 1 collaboration

Alexander W Macfarlane 1 collaboration

Eric A Ross 1 collaboration

Toshinori Hinoue 1 collaboration

Justin R Kulchycki 1 collaboration

Ryan S Burgos 1 collaboration

Mahvish Tafseer 1 collaboration

R Katherine Alpaugh 1 collaboration

Candice L Schwebel 1 collaboration

Rutika Kokate 1 collaboration

Daniel M Geynisman 1 collaboration

Matthew R Zibelman 1 collaboration

Pooja Ghatalia 1 collaboration

Peter W Nichols 1 collaboration

Woonbok Chung 1 collaboration

Jozef Madzo 1 collaboration

Noah M Hahn 1 collaboration

David I Quinn 1 collaboration

Jean-Pierre J Issa 1 collaboration

Michael J Topper 1 collaboration

Stephen B Baylin 1 collaboration

Kerry S Campbell 1 collaboration

Elizabeth R Plimack 1 collaboration

Mark D Underwood 1 collaboration

Andrew Dwork 1 collaboration

Norman Simpson 1 collaboration

Hanga Galfalvy 1 collaboration

Gorazd Rozoklija 1 collaboration

J John Mann 1 collaboration

Josh Schipper 1 collaboration

Ian Beddows 1 collaboration

David Monsma 1 collaboration

Matti Kiupel 1 collaboration

Jose R Conejo-Garcia 1 collaboration

Diptaman Chatterjee 1 collaboration

Daniel Saiz Sanchez 1 collaboration

Emmanuel Quansah 1 collaboration

Jeffrey H Kordower 1 collaboration

Yazhou Li 1 collaboration

John S Beck 1 collaboration

Calvin T Cheema 1 collaboration

Betul Kara 1 collaboration

David A Bennett 1 collaboration

Julie A Schneider 1 collaboration

Marcia N Gordon 1 collaboration

Stephen D Ginsberg 1 collaboration

Elliott J Mufson 1 collaboration

Scott E Counts 1 collaboration

Wouter Peelaerts 1 collaboration

Michaela Johnson 1 collaboration

K Peter R Nilsson 1 collaboration

Jerry R Colca 1 collaboration