Wataru Obuchi

Affiliations

R&D and Biologics Divisions, Daiichi Sankyo Co. Ltd, Shinagawa, Tokyo, Japan.

Publications (5)

Design of 2'-

Nucleosides, nucleotides & nucleic acids

Avec: Makoto Koizumi , Yasuhide Hirota , Makiko Nakayama , Masakazu Tamura , Wataru Obuchi , Akiko Kurimoto , Hiroshi Tsuchida , Hiroaki Maeda

Estimation of fraction of drug metabolism by a single UDP-glucuronosyl transferase enzyme using relative expression factor.

Biopharmaceutics & drug disposition

Avec: Tomoyo Honda , Wataru Obuchi , Yumi Nishiya , Takahiro Shibayama , Kengo Watanabe , Nobuaki Watanabe

RNA interference activity of single-stranded oligonucleotides linked between the passenger strand and the guide strand with an aryl phosphate linker.

Nucleosides, nucleotides & nucleic acids

Avec: Makoto Koizumi , Yasuhide Hirota , Makiko Nakayama , Masakazu Tamura , Wataru Obuchi

Highly potent, orally active novel small-molecule HPK1 inhibitor DS21150768 induces anti-tumor responses in multiple syngeneic tumor mouse models.

European journal of pharmacology

Avec: Genzui Setsu , Megumi Goto , Kentaro Ito , Tomoe Taira , Masaya Miyamoto , Tomohiro Watanabe , Toru Taniguchi , Yuma Umezaki , Yusuke Nakazawa , Shuhei Uesugi , Kazuki Mori , Takao Horiuchi , Wataru Obuchi , Masako Minami , Takashi Shimada , Chisa Wada , Takanori Yoshida , Saito Higuchi

Discovery of a potent, selective, and orally available EGFR C797S mutant inhibitor (DS06652923) with in vivo antitumor activity.

Bioorganic & medicinal chemistry

Avec: Hideaki Kageji , Takayuki Momose , Masayuki Ebisawa , Yusuke Nakazawa , Hiroyuki Okada , Noriko Togashi , Yasuhito Nagamoto , Wataru Obuchi , Isao Yasumatsu , Kawori Kihara , Kumiko Hiramoto , Megumi Minami , Naomi Kasanuki , Takeshi Isoyama , Hiroyuki Naito , Naoki Tanaka

Réseau de co-auteurs

Makoto Koizumi 2 collaborations

Yasuhide Hirota 2 collaborations

Makiko Nakayama 2 collaborations

Masakazu Tamura 2 collaborations

Yusuke Nakazawa 2 collaborations

Akiko Kurimoto 1 collaboration

Hiroshi Tsuchida 1 collaboration

Hiroaki Maeda 1 collaboration

Tomoyo Honda 1 collaboration

Yumi Nishiya 1 collaboration

Takahiro Shibayama 1 collaboration

Kengo Watanabe 1 collaboration

Nobuaki Watanabe 1 collaboration

Genzui Setsu 1 collaboration

Megumi Goto 1 collaboration

Kentaro Ito 1 collaboration

Tomoe Taira 1 collaboration

Masaya Miyamoto 1 collaboration

Tomohiro Watanabe 1 collaboration

Toru Taniguchi 1 collaboration

Yuma Umezaki 1 collaboration

Shuhei Uesugi 1 collaboration

Kazuki Mori 1 collaboration

Takao Horiuchi 1 collaboration

Masako Minami 1 collaboration

Takashi Shimada 1 collaboration

Chisa Wada 1 collaboration

Takanori Yoshida 1 collaboration

Saito Higuchi 1 collaboration

Hideaki Kageji 1 collaboration

Takayuki Momose 1 collaboration

Masayuki Ebisawa 1 collaboration

Hiroyuki Okada 1 collaboration

Noriko Togashi 1 collaboration

Yasuhito Nagamoto 1 collaboration

Isao Yasumatsu 1 collaboration

Kawori Kihara 1 collaboration

Kumiko Hiramoto 1 collaboration

Megumi Minami 1 collaboration

Naomi Kasanuki 1 collaboration

Takeshi Isoyama 1 collaboration

Hiroyuki Naito 1 collaboration

Naoki Tanaka 1 collaboration