Warren E Glaab

Affiliations

Safety Assessment and Laboratory Animal Resources.

Publications (23)

Polyethlyene Glycol 200 Can Protect Rats Against Drug-Induced Kidney Toxicity Through Inhibition of the Renal Organic Anion Transporter 3.

Toxicological sciences : an official journal of the Society of Toxicology

Avec: Yi-Zhong Gu , Xiaoyan Chu , Robert Houle , Katerina Vlasakova , Kenneth A Koeplinger , Isabelle Bourgeois , Kiran Palyada , Kenneth D Anderson , Christopher Brynczka , Bhavana Bhatt , Feifei Chen , Roger Smith , Rupesh Amin , Warren E Glaab , Jose Lebron , Kathleen Cox , Frank D Sistare

Use of a Bile Salt Export Pump Knockdown Rat Susceptibility Model to Interrogate Mechanism of Drug-Induced Liver Toxicity.

Toxicological sciences : an official journal of the Society of Toxicology

Avec: Yutai Li , Raymond Evers , Michael J Hafey , Kyeongmi Cheon , Hong Duong , Donna Lynch , Lisa LaFranco-Scheuch , Stephen Pacchione , Alex M Tamburino , Keith Q Tanis , Kristin Geddes , Daniel Holder , Nanyan Rena Zhang , Wen Kang , Raymond J Gonzalez , Alema Galijatovic-Idrizbegovic , Kara M Pearson , Jose A Lebron , Warren E Glaab , Frank D Sistare

Translational Safety Biomarkers of Kidney Injury.

Seminars in nephrology

Avec: Sean P Troth , Katerina Vlasakova , Shashi Amur , Rupesh P Amin , Warren E Glaab

Evaluation of Urinary Renal Biomarkers for Early Prediction of Acute Kidney Injury Following Partial Nephrectomy: A Feasibility Study.

European urology focus

Avec: Brian R Lane , Stephen K Babitz , Katerina Vlasakova , Allen Wong , Sabrina L Noyes , William Boshoven , Pam Grady , Cindy Zimmerman , Susan Engerman , Maureen Gebben , Michael Tanen , Warren E Glaab , Frank D Sistare

A MicroRNA Next-Generation-Sequencing Discovery Assay (miND) for Genome-Scale Analysis and Absolute Quantitation of Circulating MicroRNA Biomarkers.

International journal of molecular sciences

Avec: Kseniya Khamina , Andreas B Diendorfer , Susanna Skalicky , Moritz Weigl , Marianne Pultar , Teresa L Krammer , Catharine Aquino Fournier , Amy L Schofield , Carolin Otto , Aaron Thomas Smith , Nina Buchtele , Christian Schoergenhofer , Bernd Jilma , Bernhard J H Frank , Jochen G Hofstaetter , Regina Grillari , Johannes Grillari , Klemens Ruprecht , Christopher E Goldring , Hubert Rehrauer , Warren E Glaab , Matthias Hackl

A mechanistic biomarker investigation of fialuridine hepatotoxicity using the chimeric TK-NOG Hu-liver mouse model and in vitro micropatterned hepatocyte cocultures.

Toxicology research

Avec: Amy G Aslamkhan , Laura Michna , Alexei Podtelezhnikov , Katerina Vlasakova , Hiroshi Suemizu , Yasuyuki Ohnishi , Liping Liu , Pamela Lane , Qiuwei Xu , Matthew C Kuhls , Zhibin Wang , Stephen Pacchione , Zoltan Erdos , Rodger William Tracy , Kenneth Koeplinger , Nagaraja Muniappa , John Valentine , Alema Galijatovic-Idrizbegovic , Warren E Glaab , Frank D Sistare , Jose Lebron

Early-Onset albuminuria and Associated Renal Pathology in Leucine-Rich Repeat Kinase 2 Knockout Rats.

Toxicologic pathology

Avec: Yi-Zhong Gu , Katerina Vlasakova , Glen Miller , Nicholas T Gatto , Paul J Ciaccio , Sabu Kuruvilla , Elizabeth G Besteman , Roger Smith , Spencer J Reynolds , Rupesh P Amin , Warren E Glaab , Gordon Wollenberg , Jose Lebron , Frank D Sistare

Evaluation of the Relative Performance of Pancreas-Specific MicroRNAs in Rat Plasma as Biomarkers of Pancreas Injury.

Toxicological sciences : an official journal of the Society of Toxicology

Avec: Zoltan Erdos , John E Barnum , Erjia Wang , Christopher DeMaula , Paritosh Markus Dey , Thomas Forest , Wendy J Bailey , Warren E Glaab

A Performance Evaluation of Liver and Skeletal Muscle-Specific miRNAs in Rat Plasma to Detect Drug-Induced Injury.

Toxicological sciences : an official journal of the Society of Toxicology

Avec: Wendy J Bailey , John E Barnum , Zoltan Erdos , Lisa LaFranco-Scheuch , Pamela Lane , Katerina Vlasakova , Frank D Sistare , Warren E Glaab

Universal Toxicity Gene Signatures for Early Identification of Drug-Induced Tissue Injuries in Rats.

Toxicological sciences : an official journal of the Society of Toxicology

Avec: Warren E Glaab , Daniel Holder , Yudong D He , Wendy J Bailey , David L Gerhold , Carolann Beare , Zoltan Erdos , Pamela Lane , Laura Michna , Nagaraja Muniappa , Jeffrey W Lawrence , Keith Q Tanis , Joseph F Sina , Thomas R Skopek , Frank D Sistare

Universal Accessible Biomarkers of Drug-Induced Tissue Injury and Systemic Inflammation in Rat: Performance Assessment of TIMP-1, A2M, AGP, NGAL, and Albumin.

Toxicological sciences : an official journal of the Society of Toxicology

Avec: Katerina Vlasakova , Jennifer Bourque , Wendy J Bailey , Shetal Patel , Elizabeth G Besteman , Raymond J Gonzalez , Frank D Sistare , Warren E Glaab

Performance of biomarkers NF-L, NSE, Tau and GFAP in blood and cerebrospinal fluid in rat for the detection of nervous system injury.

Frontiers in neuroscience

Avec: Katerina Vlasakova , Takayuki Tsuchiya , Ivy N Garfinkel , Michael P Ruth , Cheryl Tyszkiewicz , Theodore J Detwiler , Christopher J Somps , Lorenzo Di Cesare Mannelli , Warren E Glaab

The use of emerging safety biomarkers in nonclinical and clinical safety assessment - The current and future state: An IQ DruSafe industry survey.

Regulatory toxicology and pharmacology : RTP

Avec: Tanja S Zabka , John Burkhardt , William J Reagan , Jean-Charles Gautier , Warren E Glaab , Magali Guffroy , Joanna Harding , Dominique Brees , Eric McDuffie , Lila Ramaiah , A Eric Schultze , James D Smith , Alison Wolfreys , Deidre A Dalmas

Evaluation of 10 Urinary Biomarkers for Renal Safety With 5 Nephrotoxicants in Nonhuman Primates.

Toxicologic pathology

Avec: Katerina Vlasakova , Sean P Troth , Frank D Sistare , Warren E Glaab

Characterization of indoleamine-2,3-dioxygenase 1, tryptophan-2,3-dioxygenase, and Ido1/Tdo2 knockout mice.

Toxicology and applied pharmacology

Avec: Amy G Aslamkhan , Qiuwei Xu , Amy Loughlin , Heather Vu , Stephen Pacchione , Bhavana Bhatt , Ivy Garfinkel , Tara Grady Styring , Lisa LaFranco-Scheuch , Kara Pearson , Spencer Reynolds , Nianyu Li , Heather Zhou , J Richard Miller , Nicolas Solban , Alan Bass , Warren E Glaab

Plasma biomarkers TAP, CPA1, and CPA2 for the detection of pancreatic injury in rat: the development of a novel multiplex IA-LC-MS/MS assay and biomarker performance evaluation.

Archives of toxicology

Avec: Katerina Vlasakova , Andreas Steinhilber , Wendy J Bailey , Zoltan Erdos , Hanna Haag , Thomas Joos , Bradley L Ackermann , Oliver Poetz , Warren E Glaab

Urine kidney safety biomarkers improve understanding of indirect intra-renal injury potential in dogs with a drug-induced prerenal azotemia.

Toxicology

Avec: Yi-Zhong Gu , Katerina Vlasakova , Jarig Darbes , Erjia Wang , Jude Ferraro , Warren E Glaab , Frank D Sistare

Quantitative Transcriptional Biomarkers of Xenobiotic Receptor Activation in Rat Liver for the Early Assessment of Drug Safety Liabilities.

Toxicological sciences : an official journal of the Society of Toxicology

Avec: Alexei A Podtelezhnikov , James J Monroe , Amy G Aslamkhan , Kara Pearson , Chunhua Qin , Alex M Tamburino , Andrey P Loboda , Warren E Glaab , Frank D Sistare , Keith Q Tanis

AhR Activation in Pharmaceutical Development: Applying Liver Gene Expression Biomarker Thresholds to Identify Doses Associated With Tumorigenic Risks in Rats.

Toxicological sciences : an official journal of the Society of Toxicology

Avec: Chunhua Qin , Amy G Aslamkhan , Kara Pearson , Keith Q Tanis , Alexei Podtelezhnikov , Erika Frank , Stephen Pacchione , Todd Pippert , Warren E Glaab , Frank D Sistare

Kidney Injury Monitoring in Tobramycin-Treated Rhesus Monkeys: Supplementing Urinary Kidney Biomarkers With Kidney Biopsy Gene Expression Profiling.

Toxicologic pathology

Avec: Yi-Zhong Gu , Larry Handt , Katerina Vlasakova , Vasudevan Bakthavatchalu , Roger Smith , Guillermo E Fernandez , Stephanie L Born , Warren E Glaab , Frank D Sistare

Systems analysis of miRNA biomarkers to inform drug safety.

Archives of toxicology

Avec: Amy L Schofield , Joseph P Brown , Jack Brown , Ania Wilczynska , Catherine Bell , Warren E Glaab , Matthias Hackl , Lawrence Howell , Stephen Lee , James W Dear , Mika Remes , Paul Reeves , Eunice Zhang , Jens Allmer , Alan Norris , Francesco Falciani , Louise Y Takeshita , Shiva Seyed Forootan , Robert Sutton , B Kevin Park , Chris Goldring

Magnitude of Urine Albumin and KIM-1 Changes Can be Used to Differentiate Glomerular Injury From Tubular Injury in Rats.

Toxicologic pathology

Avec: Yi-Zhong Gu , Erina Paul , Katerina Vlasakova , Sean P Troth , Frank D Sistare , Lila Ramaiah , Oliver Potz , Santosh Sutradhar , Warren E Glaab

Neurofilament light chain in plasma as a sensitive diagnostic biomarker of peripheral neurotoxicity: In Vivo mouse studies with oxaliplatin and paclitaxel - NeuroDeRisk project.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: David Balayssac , Jérôme Busserolles , Catherine Broto , Cristelle Dalbos , Laetitia Prival , Sylvain Lamoine , Damien Richard , Mercedes Quintana , Aurélia Herbet , Sandrine Hilairet , Yang Hu , Irena Loryan , Warren E Glaab , Laura Micheli , Carla Ghelardini , Lorenzo Di Cesare Mannelli , Olivier Perrault , Mohamed Slaoui

Réseau de co-auteurs

Frank D Sistare 14 collaborations

Katerina Vlasakova 13 collaborations

Yi-Zhong Gu 5 collaborations

Zoltan Erdos 5 collaborations

Wendy J Bailey 5 collaborations

Stephen Pacchione 4 collaborations

Keith Q Tanis 4 collaborations

Amy G Aslamkhan 4 collaborations

Roger Smith 3 collaborations

Jose Lebron 3 collaborations

Lisa LaFranco-Scheuch 3 collaborations

Sean P Troth 3 collaborations

Pamela Lane 3 collaborations

Kara Pearson 3 collaborations

Bhavana Bhatt 2 collaborations

Alex M Tamburino 2 collaborations

Daniel Holder 2 collaborations

Raymond J Gonzalez 2 collaborations

Alema Galijatovic-Idrizbegovic 2 collaborations

Rupesh P Amin 2 collaborations

Amy L Schofield 2 collaborations

Matthias Hackl 2 collaborations

Laura Michna 2 collaborations

Alexei Podtelezhnikov 2 collaborations

Qiuwei Xu 2 collaborations

Nagaraja Muniappa 2 collaborations

Elizabeth G Besteman 2 collaborations

John E Barnum 2 collaborations

Erjia Wang 2 collaborations

Lorenzo Di Cesare Mannelli 2 collaborations

Lila Ramaiah 2 collaborations

Chunhua Qin 2 collaborations

Xiaoyan Chu 1 collaboration

Robert Houle 1 collaboration

Kenneth A Koeplinger 1 collaboration

Isabelle Bourgeois 1 collaboration

Kiran Palyada 1 collaboration

Kenneth D Anderson 1 collaboration

Christopher Brynczka 1 collaboration

Feifei Chen 1 collaboration

Rupesh Amin 1 collaboration

Kathleen Cox 1 collaboration

Yutai Li 1 collaboration

Raymond Evers 1 collaboration

Michael J Hafey 1 collaboration

Kyeongmi Cheon 1 collaboration

Hong Duong 1 collaboration

Donna Lynch 1 collaboration

Kristin Geddes 1 collaboration

Nanyan Rena Zhang 1 collaboration

Wen Kang 1 collaboration

Kara M Pearson 1 collaboration

Jose A Lebron 1 collaboration

Shashi Amur 1 collaboration

Brian R Lane 1 collaboration

Stephen K Babitz 1 collaboration

Allen Wong 1 collaboration

Sabrina L Noyes 1 collaboration

William Boshoven 1 collaboration

Pam Grady 1 collaboration

Cindy Zimmerman 1 collaboration

Susan Engerman 1 collaboration

Maureen Gebben 1 collaboration

Michael Tanen 1 collaboration

Kseniya Khamina 1 collaboration

Andreas B Diendorfer 1 collaboration

Susanna Skalicky 1 collaboration

Moritz Weigl 1 collaboration

Marianne Pultar 1 collaboration

Teresa L Krammer 1 collaboration

Catharine Aquino Fournier 1 collaboration

Carolin Otto 1 collaboration

Aaron Thomas Smith 1 collaboration

Nina Buchtele 1 collaboration

Christian Schoergenhofer 1 collaboration

Bernd Jilma 1 collaboration

Bernhard J H Frank 1 collaboration

Jochen G Hofstaetter 1 collaboration

Regina Grillari 1 collaboration

Johannes Grillari 1 collaboration

Klemens Ruprecht 1 collaboration

Christopher E Goldring 1 collaboration

Hubert Rehrauer 1 collaboration

Hiroshi Suemizu 1 collaboration

Yasuyuki Ohnishi 1 collaboration

Liping Liu 1 collaboration

Matthew C Kuhls 1 collaboration

Zhibin Wang 1 collaboration

Rodger William Tracy 1 collaboration

Kenneth Koeplinger 1 collaboration

John Valentine 1 collaboration

Glen Miller 1 collaboration

Nicholas T Gatto 1 collaboration

Paul J Ciaccio 1 collaboration

Sabu Kuruvilla 1 collaboration

Spencer J Reynolds 1 collaboration

Gordon Wollenberg 1 collaboration

Christopher DeMaula 1 collaboration

Paritosh Markus Dey 1 collaboration

Thomas Forest 1 collaboration

Yudong D He 1 collaboration

David L Gerhold 1 collaboration

Carolann Beare 1 collaboration

Jeffrey W Lawrence 1 collaboration

Joseph F Sina 1 collaboration

Thomas R Skopek 1 collaboration

Jennifer Bourque 1 collaboration

Shetal Patel 1 collaboration

Takayuki Tsuchiya 1 collaboration

Ivy N Garfinkel 1 collaboration

Michael P Ruth 1 collaboration

Cheryl Tyszkiewicz 1 collaboration

Theodore J Detwiler 1 collaboration

Christopher J Somps 1 collaboration

Tanja S Zabka 1 collaboration

John Burkhardt 1 collaboration

William J Reagan 1 collaboration

Jean-Charles Gautier 1 collaboration

Magali Guffroy 1 collaboration

Joanna Harding 1 collaboration

Dominique Brees 1 collaboration

Eric McDuffie 1 collaboration

A Eric Schultze 1 collaboration

James D Smith 1 collaboration

Alison Wolfreys 1 collaboration

Deidre A Dalmas 1 collaboration

Amy Loughlin 1 collaboration

Heather Vu 1 collaboration

Ivy Garfinkel 1 collaboration

Tara Grady Styring 1 collaboration

Spencer Reynolds 1 collaboration

Nianyu Li 1 collaboration

Heather Zhou 1 collaboration

J Richard Miller 1 collaboration

Nicolas Solban 1 collaboration

Alan Bass 1 collaboration

Andreas Steinhilber 1 collaboration

Hanna Haag 1 collaboration

Thomas Joos 1 collaboration

Bradley L Ackermann 1 collaboration

Oliver Poetz 1 collaboration

Jarig Darbes 1 collaboration

Jude Ferraro 1 collaboration

Alexei A Podtelezhnikov 1 collaboration

James J Monroe 1 collaboration

Andrey P Loboda 1 collaboration

Erika Frank 1 collaboration

Todd Pippert 1 collaboration

Larry Handt 1 collaboration

Vasudevan Bakthavatchalu 1 collaboration

Guillermo E Fernandez 1 collaboration

Stephanie L Born 1 collaboration

Joseph P Brown 1 collaboration

Jack Brown 1 collaboration

Ania Wilczynska 1 collaboration

Catherine Bell 1 collaboration

Lawrence Howell 1 collaboration

Stephen Lee 1 collaboration

James W Dear 1 collaboration

Mika Remes 1 collaboration

Paul Reeves 1 collaboration

Eunice Zhang 1 collaboration

Jens Allmer 1 collaboration

Alan Norris 1 collaboration

Francesco Falciani 1 collaboration

Louise Y Takeshita 1 collaboration

Shiva Seyed Forootan 1 collaboration

Robert Sutton 1 collaboration

B Kevin Park 1 collaboration

Chris Goldring 1 collaboration

Erina Paul 1 collaboration

Oliver Potz 1 collaboration

Santosh Sutradhar 1 collaboration

David Balayssac 1 collaboration

Jérôme Busserolles 1 collaboration

Catherine Broto 1 collaboration

Cristelle Dalbos 1 collaboration

Laetitia Prival 1 collaboration

Sylvain Lamoine 1 collaboration

Damien Richard 1 collaboration

Mercedes Quintana 1 collaboration

Aurélia Herbet 1 collaboration

Sandrine Hilairet 1 collaboration

Yang Hu 1 collaboration

Irena Loryan 1 collaboration

Laura Micheli 1 collaboration

Carla Ghelardini 1 collaboration

Olivier Perrault 1 collaboration

Mohamed Slaoui 1 collaboration