Irena Loryan

Affiliations

Translational PKPD Group, Department of Pharmaceutical Biosciences, Associate Member of SciLifeLab, Uppsala University, Uppsala, Sweden.

ORCID: http://orcid.org/0000-0002-1557-4416

Publications (17)

Molecular basis of mood and cognitive adverse events elucidated via a combination of pharmacovigilance data mining and functional enrichment analysis.

Archives of toxicology

Avec: Christos Andronis , João Pedro Silva , Eftychia Lekka , Vassilis Virvilis , Helena Carmo , Konstantina Bampali , Margot Ernst , Yang Hu , Jacques Richard , Félix Carvalho , Miroslav M Savić

Brain barriers virtual: an interim solution or future opportunity?

Fluids and barriers of the CNS

Avec: Brianna M Holder , Shaina E Tolan , Kaleb K Heinrich , Kaitlin C Miller , Natalie Hudson , Geetika Nehra , Michelle E Pizzo , Steffen E Storck , William F Elmquist , Britta Engelhardt , Michal Toborek , Bjoern Bauer , Anika M S Hartz , Brandon J Kim

Amorphisation of Free Acid Ibuprofen and Other Profens in Mixtures with Nanocellulose: Dry Powder Formulation Strategy for Enhanced Solubility.

Pharmaceutics

Avec: Athanasios Mantas , Valentine Labbe , Albert Mihranyan

Heterogeneous drug tissue binding in brain regions of rats, Alzheimer's patients and controls: impact on translational drug development.

Scientific reports

Avec: Sofia Gustafsson , Dag Sehlin , Erik Lampa , Margareta Hammarlund-Udenaes ,

Regional distribution of unbound eletriptan and sumatriptan in the CNS and PNS in rats: implications for a potential central action.

The journal of headache and pain

Avec: Nana Svane , Frida Bällgren , Aghavni Ginosyan , Mie Kristensen , Birger Brodin ,

In Vivo Studies of Drug BBB Transport: Translational Challenges and the Role of Brain Imaging.

Handbook of experimental pharmacology

Avec: Stina Syvänen , Margareta Hammarlund-Udenaes ,

Neurofilament light chain in plasma as a sensitive diagnostic biomarker of peripheral neurotoxicity: In Vivo mouse studies with oxaliplatin and paclitaxel - NeuroDeRisk project.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: David Balayssac , Jérôme Busserolles , Catherine Broto , Cristelle Dalbos , Laetitia Prival , Sylvain Lamoine , Damien Richard , Mercedes Quintana , Aurélia Herbet , Sandrine Hilairet , Yang Hu , Warren E Glaab , Laura Micheli , Carla Ghelardini , Lorenzo Di Cesare Mannelli , Olivier Perrault , Mohamed Slaoui

The solute carrier SLC7A1 may act as a protein transporter at the blood-brain barrier.

European journal of cell biology

Avec: Magdalena Kurtyka , Frank Wessely , Sarah Bau , Eseoghene Ifie , Liqun He , Nienke M de Wit , Alberte Bay Villekjær Pedersen , Maximilian Keller , Caleb Webber , Helga E de Vries , Olaf Ansorge , Christer Betsholtz , Marijke De Bock , Catarina Chaves , Birger Brodin , Morten S Nielsen , Winfried Neuhaus , Robert D Bell , Tamás Letoha , Axel H Meyer , Germán Leparc , Martin Lenter , Dominique Lesuisse , Zameel M Cader , Stephen T Buckley , Claus U Pietrzik

Mechanistic Study on the Use of the l-Type Amino Acid Transporter 1 for Brain Intracellular Delivery of Ketoprofen via Prodrug: A Novel Approach Supporting the Development of Prodrugs for Intracellular Targets.

Molecular pharmaceutics

Avec: Elena Puris , Mikko Gynther , Elizabeth C M de Lange , Seppo Auriola , Margareta Hammarlund-Udenaes , Kristiina M Huttunen ,

Brain Distribution of Drugs: Pharmacokinetic Considerations.

Handbook of experimental pharmacology

Avec: Margareta Hammarlund-Udenaes , Stina Syvänen

Unbound Brain-to-Plasma Partition Coefficient, K

Pharmaceutical research

Avec: Andreas Reichel , Bo Feng , Christoffer Bundgaard , Christopher Shaffer , Cory Kalvass , Dallas Bednarczyk , Denise Morrison , Dominique Lesuisse , Edmund Hoppe , Georg C Terstappen , Holger Fischer , Li Di , Nicola Colclough , Scott Summerfield , Stephen T Buckley , Tristan S Maurer , Markus Fridén

Differential Blood-Brain Barrier Transport and Cell Uptake of Cyclic Peptides In Vivo and In Vitro.

Pharmaceutics

Avec: Erik Melander , Camilla Eriksson , Sara Wellens , Kimia Hosseini , Robert Fredriksson , Fabien Gosselet , Maxime Culot , Ulf Göransson , Margareta Hammarlund-Udenaes ,

Rate and extent of mitragynine and 7-hydroxymitragynine blood-brain barrier transport and their intra-brain distribution: the missing link in pharmacodynamic studies.

Addiction biology

Avec: Siti R Yusof , Mahathir Mohd Uzid , Eng-Huat Teh , Nur Aziah Hanapi , Mazlin Mohideen , Ahmad Saifuddin Mohamad Arshad , Mohd Nizam Mordi , Margareta Hammarlund-Udenaes

Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood-brain barrier.

Molecular psychiatry

Avec: Dominika Luptáková , Theodosia Vallianatou , Anna Nilsson , Reza Shariatgorji , Margareta Hammarlund-Udenaes , Per E Andrén

Active Uptake of Oxycodone at Both the Blood-Cerebrospinal Fluid Barrier and The Blood-Brain Barrier without Sex Differences: A Rat Microdialysis Study.

Pharmaceutical research

Avec: Frida Bällgren , Margareta Hammarlund-Udenaes ,

Analysis of the contributing role of drug transport across biological barriers in the development and treatment of chemotherapy-induced peripheral neuropathy.

Fluids and barriers of the CNS

Avec: Yang Hu , Milda Girdenyté , Lieke Roest , Iida Liukkonen , Maria Siskou , Frida Bällgren , Margareta Hammarlund-Udenaes ,

Active CNS delivery of oxycodone in healthy and endotoxemic pigs.

Fluids and barriers of the CNS

Avec: Frida Bällgren , Tilda Bergfast , Aghavni Ginosyan , Jessica Mahajan , Miklós Lipcsey , Margareta Hammarlund-Udenaes , Stina Syvänen ,

Réseau de co-auteurs

Margareta Hammarlund-Udenaes 10 collaborations

Frida Bällgren 4 collaborations

Yang Hu 3 collaborations

Stina Syvänen 3 collaborations

Aghavni Ginosyan 2 collaborations

Birger Brodin 2 collaborations

Dominique Lesuisse 2 collaborations

Stephen T Buckley 2 collaborations

Christos Andronis 1 collaboration

João Pedro Silva 1 collaboration

Eftychia Lekka 1 collaboration

Vassilis Virvilis 1 collaboration

Helena Carmo 1 collaboration

Konstantina Bampali 1 collaboration

Margot Ernst 1 collaboration

Jacques Richard 1 collaboration

Félix Carvalho 1 collaboration

Miroslav M Savić 1 collaboration

Brianna M Holder 1 collaboration

Shaina E Tolan 1 collaboration

Kaleb K Heinrich 1 collaboration

Kaitlin C Miller 1 collaboration

Natalie Hudson 1 collaboration

Geetika Nehra 1 collaboration

Michelle E Pizzo 1 collaboration

Steffen E Storck 1 collaboration

William F Elmquist 1 collaboration

Britta Engelhardt 1 collaboration

Michal Toborek 1 collaboration

Bjoern Bauer 1 collaboration

Anika M S Hartz 1 collaboration

Brandon J Kim 1 collaboration

Athanasios Mantas 1 collaboration

Valentine Labbe 1 collaboration

Albert Mihranyan 1 collaboration

Sofia Gustafsson 1 collaboration

Dag Sehlin 1 collaboration

Erik Lampa 1 collaboration

Nana Svane 1 collaboration

Mie Kristensen 1 collaboration

David Balayssac 1 collaboration

Jérôme Busserolles 1 collaboration

Catherine Broto 1 collaboration

Cristelle Dalbos 1 collaboration

Laetitia Prival 1 collaboration

Sylvain Lamoine 1 collaboration

Damien Richard 1 collaboration

Mercedes Quintana 1 collaboration

Aurélia Herbet 1 collaboration

Sandrine Hilairet 1 collaboration

Warren E Glaab 1 collaboration

Laura Micheli 1 collaboration

Carla Ghelardini 1 collaboration

Lorenzo Di Cesare Mannelli 1 collaboration

Olivier Perrault 1 collaboration

Mohamed Slaoui 1 collaboration

Magdalena Kurtyka 1 collaboration

Frank Wessely 1 collaboration

Sarah Bau 1 collaboration

Eseoghene Ifie 1 collaboration

Liqun He 1 collaboration

Nienke M de Wit 1 collaboration

Alberte Bay Villekjær Pedersen 1 collaboration

Maximilian Keller 1 collaboration

Caleb Webber 1 collaboration

Helga E de Vries 1 collaboration

Olaf Ansorge 1 collaboration

Christer Betsholtz 1 collaboration

Marijke De Bock 1 collaboration

Catarina Chaves 1 collaboration

Morten S Nielsen 1 collaboration

Winfried Neuhaus 1 collaboration

Robert D Bell 1 collaboration

Tamás Letoha 1 collaboration

Axel H Meyer 1 collaboration

Germán Leparc 1 collaboration

Martin Lenter 1 collaboration

Zameel M Cader 1 collaboration

Claus U Pietrzik 1 collaboration

Elena Puris 1 collaboration

Mikko Gynther 1 collaboration

Elizabeth C M de Lange 1 collaboration

Seppo Auriola 1 collaboration

Kristiina M Huttunen 1 collaboration

Andreas Reichel 1 collaboration

Bo Feng 1 collaboration

Christoffer Bundgaard 1 collaboration

Christopher Shaffer 1 collaboration

Cory Kalvass 1 collaboration

Dallas Bednarczyk 1 collaboration

Denise Morrison 1 collaboration

Edmund Hoppe 1 collaboration

Georg C Terstappen 1 collaboration

Holger Fischer 1 collaboration

Li Di 1 collaboration

Nicola Colclough 1 collaboration

Scott Summerfield 1 collaboration

Tristan S Maurer 1 collaboration

Markus Fridén 1 collaboration

Erik Melander 1 collaboration

Camilla Eriksson 1 collaboration

Sara Wellens 1 collaboration

Kimia Hosseini 1 collaboration

Robert Fredriksson 1 collaboration

Fabien Gosselet 1 collaboration

Maxime Culot 1 collaboration

Ulf Göransson 1 collaboration

Siti R Yusof 1 collaboration

Mahathir Mohd Uzid 1 collaboration

Eng-Huat Teh 1 collaboration

Nur Aziah Hanapi 1 collaboration

Mazlin Mohideen 1 collaboration

Ahmad Saifuddin Mohamad Arshad 1 collaboration

Mohd Nizam Mordi 1 collaboration

Dominika Luptáková 1 collaboration

Theodosia Vallianatou 1 collaboration

Anna Nilsson 1 collaboration

Reza Shariatgorji 1 collaboration

Per E Andrén 1 collaboration

Milda Girdenyté 1 collaboration

Lieke Roest 1 collaboration

Iida Liukkonen 1 collaboration

Maria Siskou 1 collaboration

Tilda Bergfast 1 collaboration

Jessica Mahajan 1 collaboration

Miklós Lipcsey 1 collaboration