Ville Hietakangas

Affiliations

Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Finland.
Institute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki, Finland.

ORCID: 0000-0002-9900-7549

Publications (18)

Cellular and physiological roles of the conserved atypical MAP kinase ERK7.

FEBS letters

Avec: Onur Deniz , Kiran Hasygar , Ville Hietakangas

Cancer research

Avec: Xi Qiao , Ying Liu , Maria Llamazares Prada , Aravind K Mohan , Abhishekh Gupta , Alok Jaiswal , Mukund Sharma , Joni Merisaari , Heidi M Haikala , Kati Talvinen , Laxman Yetukuri , Joanna W Pylvänäinen , Juha Klefström , Pauliina Kronqvist , Annika Meinander , Tero Aittokallio , Ville Hietakangas , Martin Eilers , Jukka Westermarck

Metabolic determination of cell fate through selective inheritance of mitochondria.

Nature cell biology

Avec: Julia Döhla , Emilia Kuuluvainen , Nadja Gebert , Ana Amaral , Johanna I Englund , Swetha Gopalakrishnan , Svetlana Konovalova , Anni I Nieminen , Ella S Salminen , Rubén Torregrosa Muñumer , Kati Ahlqvist , Yang Yang , Hien Bui , Timo Otonkoski , Reijo Käkelä , Ville Hietakangas , Henna Tyynismaa , Alessandro Ori , Pekka Katajisto

Sugar-responsive inhibition of Myc-dependent ribosome biogenesis by Clockwork orange.

Cell reports

Avec: Linda van den Berg , Krista Kokki , Sylvia J Wowro , Konstantin M Petricek , Onur Deniz , Catrin A Stegmann , Marius Robciuc , Mari Teesalu , Richard G Melvin , Anni I Nieminen , Michael Schupp , Ville Hietakangas

Effects on Dopaminergic Neurons Are Secondary in COX-Deficient Locomotor Dysfunction in Drosophila.

iScience

Avec: Cagri Yalgin , Bohdana Rovenko , Ana Andjelković , Margot Neefjes , Burak Oymak , Eric Dufour , Ville Hietakangas , Howard T Jacobs

Coordinated control of adiposity and growth by anti-anabolic kinase ERK7.

EMBO reports

Avec: Kiran Hasygar , Onur Deniz , Ying Liu , Josef Gullmets , Riikka Hynynen , Hanna Ruhanen , Krista Kokki , Reijo Käkelä , Ville Hietakangas

Global analysis of aging-related protein structural changes uncovers enzyme-polymerization-based control of longevity.

Molecular cell

Avec: Jurgita Paukštytė , Rosa María López Cabezas , Yuehan Feng , Kai Tong , Daniela Schnyder , Ellinoora Elomaa , Pavlina Gregorova , Matteo Doudin , Meeri Särkkä , Jesse Sarameri , Alice Lippi , Helena Vihinen , Juhana Juutila , Anni Nieminen , Petri Törönen , Liisa Holm , Eija Jokitalo , Anita Krisko , Juha Huiskonen , L Peter Sarin , Ville Hietakangas , Paola Picotti , Yves Barral , Juha Saarikangas

Stem cell mTOR signaling directs region-specific cell fate decisions during intestinal nutrient adaptation.

Science advances

Avec: Jaakko Mattila , Arto Viitanen , Gaia Fabris , Tetiana Strutynska , Jerome Korzelius , Ville Hietakangas

Systematic Screen for

G3 (Bethesda, Md.)

Avec: Ying Liu , Jaakko Mattila , Ville Hietakangas

An image analysis method for regionally defined cellular phenotyping of the

Cell reports methods

Avec: Arto Viitanen , Josef Gullmets , Jack Morikka , Pekka Katajisto , Jaakko Mattila , Ville Hietakangas

Metabolic gene regulation by Drosophila GATA transcription factor Grain.

PLoS genetics

Avec: Krista Kokki , Nicole Lamichane , Anni I Nieminen , Hanna Ruhanen , Jack Morikka , Marius Robciuc , Bohdana M Rovenko , Essi Havula , Reijo Käkelä , Ville Hietakangas

Genetic and functional correction of argininosuccinate lyase deficiency using CRISPR adenine base editors.

American journal of human genetics

Avec: Sami Jalil , Timo Keskinen , Juhana Juutila , Rocio Sartori Maldonado , Liliya Euro , Anu Suomalainen , Risto Lapatto , Emilia Kuuluvainen , Ville Hietakangas , Timo Otonkoski , Mervi E Hyvönen , Kirmo Wartiovaara

MLX phosphorylation stabilizes the ChREBP-MLX heterotetramer on tandem E-boxes to control carbohydrate and lipid metabolism.

bioRxiv : the preprint server for biology

Avec: Carla E Cadena Del Castillo , Onur Deniz , Femke van Geest , Lore Rosseels , Ingrid Stockmans , Marius Robciuc , Sebastien Carpentier , Bettina K Wölnerhanssen , Anne Christin Meyer-Gerspach , Ralph Peterli , Ville Hietakangas , Mitsugu Shimobayashi

NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.

Nature

Avec: Dustin J Flanagan , Nalle Pentinmikko , Kalle Luopajärvi , Nicky J Willis , Kathryn Gilroy , Alexander P Raven , Lynn Mcgarry , Johanna I Englund , Anna T Webb , Sandra Scharaw , Nadia Nasreddin , Michael C Hodder , Rachel A Ridgway , Emma Minnee , Nathalie Sphyris , Ella Gilchrist , Arafath K Najumudeen , Beatrice Romagnolo , Christine Perret , Ann C Williams , Hans Clevers , Pirjo Nummela , Marianne Lähde , Kari Alitalo , Ville Hietakangas , Ann Hedley , William Clark , Colin Nixon , Kristina Kirschner , E Yvonne Jones , Ari Ristimäki , Simon J Leedham , Paul V Fish , Jean-Paul Vincent , Pekka Katajisto , Owen J Sansom

Genetic variation of macronutrient tolerance in Drosophila melanogaster.

Nature communications

Avec: E Havula , S Ghazanfar , N Lamichane , D Francis , K Hasygar , Y Liu , L A Alton , J Johnstone , E J Needham , T Pulpitel , T Clark , H N Niranjan , V Shang , V Tong , N Jiwnani , G Audia , A N Alves , L Sylow , C Mirth , G G Neely , J Yang , V Hietakangas , S J Simpson , A M Senior

Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells.

Nature biotechnology

Avec: Diego Balboa , Tom Barsby , Väinö Lithovius , Jonna Saarimäki-Vire , Muhmmad Omar-Hmeadi , Oleg Dyachok , Hossam Montaser , Per-Eric Lund , Mingyu Yang , Hazem Ibrahim , Anna Näätänen , Vikash Chandra , Helena Vihinen , Eija Jokitalo , Jouni Kvist , Jarkko Ustinov , Anni I Nieminen , Emilia Kuuluvainen , Ville Hietakangas , Pekka Katajisto , Joey Lau , Per-Ola Carlsson , Sebastian Barg , Anders Tengholm , Timo Otonkoski

Aberrant metabolite trafficking and fuel sensitivity in human pluripotent stem cell-derived islets.

Cell reports

Avec: Tom Barsby , Eliisa Vähäkangas , Jarkko Ustinov , Hossam Montaser , Hazem Ibrahim , Väinö Lithovius , Emilia Kuuluvainen , Vikash Chandra , Jonna Saarimäki-Vire , Pekka Katajisto , Ville Hietakangas , Timo Otonkoski

Human IP

Cell calcium

Avec: Julius Rönkkö , Yago Rodriguez , Tiina Rasila , Rubén Torregrosa-Muñumer , Jana Pennonen , Jouni Kvist , Emilia Kuuluvainen , Ludo Van Den Bosch , Ville Hietakangas , Geert Bultynck , Henna Tyynismaa , Emil Ylikallio

Réseau de co-auteurs

Emilia Kuuluvainen 5 collaborations

Pekka Katajisto 5 collaborations

Onur Deniz 4 collaborations

Anni I Nieminen 4 collaborations

Timo Otonkoski 4 collaborations

Ying Liu 3 collaborations

Reijo Käkelä 3 collaborations

Krista Kokki 3 collaborations

Marius Robciuc 3 collaborations

Jaakko Mattila 3 collaborations

Kiran Hasygar 2 collaborations

Johanna I Englund 2 collaborations

Henna Tyynismaa 2 collaborations

Josef Gullmets 2 collaborations

Hanna Ruhanen 2 collaborations

Helena Vihinen 2 collaborations

Juhana Juutila 2 collaborations

Eija Jokitalo 2 collaborations

Arto Viitanen 2 collaborations

Jack Morikka 2 collaborations

Tom Barsby 2 collaborations

Väinö Lithovius 2 collaborations

Jonna Saarimäki-Vire 2 collaborations

Hossam Montaser 2 collaborations

Hazem Ibrahim 2 collaborations

Vikash Chandra 2 collaborations

Jouni Kvist 2 collaborations

Jarkko Ustinov 2 collaborations

Xi Qiao 1 collaboration

Maria Llamazares Prada 1 collaboration

Aravind K Mohan 1 collaboration

Abhishekh Gupta 1 collaboration

Alok Jaiswal 1 collaboration

Mukund Sharma 1 collaboration

Joni Merisaari 1 collaboration

Heidi M Haikala 1 collaboration

Kati Talvinen 1 collaboration

Laxman Yetukuri 1 collaboration

Joanna W Pylvänäinen 1 collaboration

Juha Klefström 1 collaboration

Pauliina Kronqvist 1 collaboration

Annika Meinander 1 collaboration

Tero Aittokallio 1 collaboration

Martin Eilers 1 collaboration

Jukka Westermarck 1 collaboration

Julia Döhla 1 collaboration

Nadja Gebert 1 collaboration

Ana Amaral 1 collaboration

Swetha Gopalakrishnan 1 collaboration

Svetlana Konovalova 1 collaboration

Ella S Salminen 1 collaboration

Rubén Torregrosa Muñumer 1 collaboration

Kati Ahlqvist 1 collaboration

Yang Yang 1 collaboration

Hien Bui 1 collaboration

Alessandro Ori 1 collaboration

Linda van den Berg 1 collaboration

Sylvia J Wowro 1 collaboration

Konstantin M Petricek 1 collaboration

Catrin A Stegmann 1 collaboration

Mari Teesalu 1 collaboration

Richard G Melvin 1 collaboration

Michael Schupp 1 collaboration

Cagri Yalgin 1 collaboration

Bohdana Rovenko 1 collaboration

Ana Andjelković 1 collaboration

Margot Neefjes 1 collaboration

Burak Oymak 1 collaboration

Eric Dufour 1 collaboration

Howard T Jacobs 1 collaboration

Riikka Hynynen 1 collaboration

Jurgita Paukštytė 1 collaboration

Rosa María López Cabezas 1 collaboration

Yuehan Feng 1 collaboration

Kai Tong 1 collaboration

Daniela Schnyder 1 collaboration

Ellinoora Elomaa 1 collaboration

Pavlina Gregorova 1 collaboration

Matteo Doudin 1 collaboration

Meeri Särkkä 1 collaboration

Jesse Sarameri 1 collaboration

Alice Lippi 1 collaboration

Anni Nieminen 1 collaboration

Petri Törönen 1 collaboration

Liisa Holm 1 collaboration

Anita Krisko 1 collaboration

Juha Huiskonen 1 collaboration

L Peter Sarin 1 collaboration

Paola Picotti 1 collaboration

Yves Barral 1 collaboration

Juha Saarikangas 1 collaboration

Gaia Fabris 1 collaboration

Tetiana Strutynska 1 collaboration

Jerome Korzelius 1 collaboration

Nicole Lamichane 1 collaboration

Bohdana M Rovenko 1 collaboration

Essi Havula 1 collaboration

Sami Jalil 1 collaboration

Timo Keskinen 1 collaboration

Rocio Sartori Maldonado 1 collaboration

Liliya Euro 1 collaboration

Anu Suomalainen 1 collaboration

Risto Lapatto 1 collaboration

Mervi E Hyvönen 1 collaboration

Kirmo Wartiovaara 1 collaboration

Carla E Cadena Del Castillo 1 collaboration

Femke van Geest 1 collaboration

Lore Rosseels 1 collaboration

Ingrid Stockmans 1 collaboration

Sebastien Carpentier 1 collaboration

Bettina K Wölnerhanssen 1 collaboration

Anne Christin Meyer-Gerspach 1 collaboration

Ralph Peterli 1 collaboration

Mitsugu Shimobayashi 1 collaboration

Dustin J Flanagan 1 collaboration

Nalle Pentinmikko 1 collaboration

Kalle Luopajärvi 1 collaboration

Nicky J Willis 1 collaboration

Kathryn Gilroy 1 collaboration

Alexander P Raven 1 collaboration

Lynn Mcgarry 1 collaboration

Anna T Webb 1 collaboration

Sandra Scharaw 1 collaboration

Nadia Nasreddin 1 collaboration

Michael C Hodder 1 collaboration

Rachel A Ridgway 1 collaboration

Emma Minnee 1 collaboration

Nathalie Sphyris 1 collaboration

Ella Gilchrist 1 collaboration

Arafath K Najumudeen 1 collaboration

Beatrice Romagnolo 1 collaboration

Christine Perret 1 collaboration

Ann C Williams 1 collaboration

Hans Clevers 1 collaboration

Pirjo Nummela 1 collaboration

Marianne Lähde 1 collaboration

Kari Alitalo 1 collaboration

Ann Hedley 1 collaboration

William Clark 1 collaboration

Colin Nixon 1 collaboration

Kristina Kirschner 1 collaboration

E Yvonne Jones 1 collaboration

Ari Ristimäki 1 collaboration

Simon J Leedham 1 collaboration

Paul V Fish 1 collaboration

Jean-Paul Vincent 1 collaboration

Owen J Sansom 1 collaboration

E Havula 1 collaboration

S Ghazanfar 1 collaboration

N Lamichane 1 collaboration

D Francis 1 collaboration

K Hasygar 1 collaboration

Y Liu 1 collaboration

L A Alton 1 collaboration

J Johnstone 1 collaboration

E J Needham 1 collaboration

T Pulpitel 1 collaboration

T Clark 1 collaboration

H N Niranjan 1 collaboration

V Shang 1 collaboration

V Tong 1 collaboration

N Jiwnani 1 collaboration

G Audia 1 collaboration

A N Alves 1 collaboration

L Sylow 1 collaboration

C Mirth 1 collaboration

G G Neely 1 collaboration

J Yang 1 collaboration

V Hietakangas 1 collaboration

S J Simpson 1 collaboration

A M Senior 1 collaboration

Diego Balboa 1 collaboration

Muhmmad Omar-Hmeadi 1 collaboration

Oleg Dyachok 1 collaboration

Per-Eric Lund 1 collaboration

Mingyu Yang 1 collaboration

Anna Näätänen 1 collaboration

Joey Lau 1 collaboration

Per-Ola Carlsson 1 collaboration

Sebastian Barg 1 collaboration

Anders Tengholm 1 collaboration

Eliisa Vähäkangas 1 collaboration

Julius Rönkkö 1 collaboration

Yago Rodriguez 1 collaboration

Tiina Rasila 1 collaboration

Rubén Torregrosa-Muñumer 1 collaboration

Jana Pennonen 1 collaboration

Ludo Van Den Bosch 1 collaboration

Geert Bultynck 1 collaboration

Emil Ylikallio 1 collaboration