Valentina Barcherini

Affiliations

Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.

Publications (8)

SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma.

Cancers

Avec: Sara Gomes , Bartolomeo Bosco , Joana B Loureiro , Helena Ramos , Liliana Raimundo , Joana Soares , Nair Nazareth , Valentina Barcherini , Lucília Domingues , Carla Oliveira , Alessandra Bisio , Silvano Piazza , Matthias R Bauer , João P Brás , Maria Inês Almeida , Célia Gomes , Flávio Reis , Alan R Fersht , Alberto Inga , Maria M M Santos , Lucília Saraiva

Potency and Selectivity Optimization of Tryptophanol-Derived Oxazoloisoindolinones: Novel p53 Activators in Human Colorectal Cancer.

ChemMedChem

Avec: Valentina Barcherini , Joana Almeida , Elizabeth A Lopes , Mi Wang , Diogo Magalhães E Silva , Mattia Mori , Shaomeng Wang , Lucília Saraiva , Maria M M Santos

Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance.

Cancers

Avec: Joana B Loureiro , Liliana Raimundo , Juliana Calheiros , Carla Carvalho , Valentina Barcherini , Nuno R Lima , Célia Gomes , Maria Inês Almeida , Marco G Alves , José Luís Costa , Maria M M Santos , Lucília Saraiva

SLMP53-1 Inhibits Tumor Cell Growth through Regulation of Glucose Metabolism and Angiogenesis in a P53-Dependent Manner.

International journal of molecular sciences

Avec: Helena Ramos , Juliana Calheiros , Joana Almeida , Valentina Barcherini , Sónia Santos , Alexandra T P Carvalho , Maria M M Santos , Lucília Saraiva

Tryptophanol-Derived Oxazolopyrrolidone Lactams as Potential Anticancer Agents against Gastric Adenocarcinoma.

Pharmaceuticals (Basel, Switzerland)

Avec: Margarida Espadinha , Valentina Barcherini , Lídia M Gonçalves , Elies Molins , Alexandra M M Antunes , Maria M M Santos

SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations.

Biochimica et biophysica acta. General subjects

Avec: Ana Sara Gomes , Helena Ramos , Sara Gomes , Joana B Loureiro , Joana Soares , Valentina Barcherini , Paola Monti , Gilberto Fronza , Carla Oliveira , Lucília Domingues , Margarida Bastos , Daniel F A R Dourado , Ana Luísa Carvalho , Maria João Romão , Benedita Pinheiro , Filipa Marcelo , Alexandra Carvalho , Maria M M Santos , Lucília Saraiva

Metabolism-Guided Optimization of Tryptophanol-Derived Isoindolinone p53 Activators.

Pharmaceuticals (Basel, Switzerland)

Avec: Valentina Barcherini , Joana B Loureiro , Ana Sena , Catarina Madeira , Paula Leandro , Lucília Saraiva , Alexandra M M Antunes , Maria M M Santos

First fragment-based screening identifies new chemotypes inhibiting ERAP1-metalloprotease.

European journal of medicinal chemistry

Avec: Vasileios Fougiaxis , Valentina Barcherini , Milena M Petrovic , Pierre Sierocki , Sandrine Warenghem , Florence Leroux , Nour Bou Karroum , Fabien Petit-Cancelier , Vincent Rodeschini , Didier Roche , Benoit Deprez , Rebecca Deprez-Poulain

Réseau de co-auteurs

Maria M M Santos 7 collaborations

Lucília Saraiva 6 collaborations

Joana B Loureiro 4 collaborations

Helena Ramos 3 collaborations

Sara Gomes 2 collaborations

Liliana Raimundo 2 collaborations

Joana Soares 2 collaborations

Lucília Domingues 2 collaborations

Carla Oliveira 2 collaborations

Maria Inês Almeida 2 collaborations

Célia Gomes 2 collaborations

Joana Almeida 2 collaborations

Juliana Calheiros 2 collaborations

Alexandra M M Antunes 2 collaborations

Bartolomeo Bosco 1 collaboration

Nair Nazareth 1 collaboration

Alessandra Bisio 1 collaboration

Silvano Piazza 1 collaboration

Matthias R Bauer 1 collaboration

João P Brás 1 collaboration

Flávio Reis 1 collaboration

Alan R Fersht 1 collaboration

Alberto Inga 1 collaboration

Elizabeth A Lopes 1 collaboration

Mi Wang 1 collaboration

Diogo Magalhães E Silva 1 collaboration

Mattia Mori 1 collaboration

Shaomeng Wang 1 collaboration

Carla Carvalho 1 collaboration

Nuno R Lima 1 collaboration

Marco G Alves 1 collaboration

José Luís Costa 1 collaboration

Sónia Santos 1 collaboration

Alexandra T P Carvalho 1 collaboration

Margarida Espadinha 1 collaboration

Lídia M Gonçalves 1 collaboration

Elies Molins 1 collaboration

Ana Sara Gomes 1 collaboration

Paola Monti 1 collaboration

Gilberto Fronza 1 collaboration

Margarida Bastos 1 collaboration

Daniel F A R Dourado 1 collaboration

Ana Luísa Carvalho 1 collaboration

Maria João Romão 1 collaboration

Benedita Pinheiro 1 collaboration

Filipa Marcelo 1 collaboration

Alexandra Carvalho 1 collaboration

Ana Sena 1 collaboration

Catarina Madeira 1 collaboration

Paula Leandro 1 collaboration

Vasileios Fougiaxis 1 collaboration

Milena M Petrovic 1 collaboration

Pierre Sierocki 1 collaboration

Sandrine Warenghem 1 collaboration

Florence Leroux 1 collaboration

Nour Bou Karroum 1 collaboration

Fabien Petit-Cancelier 1 collaboration

Vincent Rodeschini 1 collaboration

Didier Roche 1 collaboration

Benoit Deprez 1 collaboration

Rebecca Deprez-Poulain 1 collaboration