Margarida Espadinha

Affiliations

Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.

Publications (8)

Discovery of MDM2-p53 and MDM4-p53 protein-protein interactions small molecule dual inhibitors.

European journal of medicinal chemistry

Avec: Elizabeth A Lopes , Vanda Marques , Joana D Amaral , Daniel J V A Dos Santos , Mattia Mori , Simona Daniele , Rebecca Piccarducci , Elisa Zappelli , Claudia Martini , Cecília M P Rodrigues , Maria M M Santos

Identification of tetracyclic lactams as NMDA receptor antagonists with potential application in neurological disorders.

European journal of medicinal chemistry

Avec: Lucía Viejo , Ricardo M R M Lopes , Clara Herrera-Arozamena , Elies Molins , Daniel J V A Dos Santos , Lídia Gonçalves , María Isabel Rodríguez-Franco , Cristóbal de Los Ríos , Maria M M Santos

Exploiting the antiproliferative potential of spiropyrazoline oxindoles in a human ovarian cancer cell line.

Bioorganic & medicinal chemistry

Avec: Luís R Raposo , Ana Silva , Dário Silva , Catarina Roma-Rodrigues , Pedro V Baptista , Maria M M Santos , Alexandra R Fernandes

Highly Selective Inhibitors of Dipeptidyl Peptidase 9 (DPP9) Derived from the Clinically Used DPP4-Inhibitor Vildagliptin.

Journal of medicinal chemistry

Avec: Siham Benramdane , Joni De Loose , Nicolò Filippi , Olivier Beyens , Yentl Van Rymenant , Laura Dirkx , Murat Bozdag , Pim-Bart Feijens , Koen Augustyns , Guy Caljon , Hans De Winter , Ingrid De Meester , Pieter Van der Veken

Active site-directed probes targeting dipeptidyl peptidases 8 and 9.

European journal of medicinal chemistry

Avec: Joni De Loose , Sam Corthaut , Sofie Thys , Yentl Van Rymenant , Emile Verhulst , Siham Benramdane , Nicolò Filippi , Koen Augustyns , Pieter Van Wielendaele , Isabel Pintelon , Ingrid De Meester , Pieter Van der Veken

Hybrid molecules of protoflavones and spirooxindole derivatives with selective cytotoxicity against triple-negative breast cancer cells.

RSC medicinal chemistry

Avec: Gábor Girst , Elizabeth A Lopes , Lídia M Gonçalves , Norbert Kúsz , Hui-Chun Wang , Maria M M Santos , Attila Hunyadi

Tryptophanol-Derived Oxazolopyrrolidone Lactams as Potential Anticancer Agents against Gastric Adenocarcinoma.

Pharmaceuticals (Basel, Switzerland)

Avec: Valentina Barcherini , Lídia M Gonçalves , Elies Molins , Alexandra M M Antunes , Maria M M Santos

Tryptophanol-derived oxazoloisoindolinone fluorescent probes for cellular localization studies of p53 activators.

Bioorganic chemistry

Avec: Hélio L Barros , Sandra N Pinto , Ricardo J F Ferreira , Joana B Loureiro , Rita Silva , Lucília Saraiva , Ermelinda Maçôas , Maria M M Santos

Réseau de co-auteurs

Maria M M Santos 6 collaborations

Elizabeth A Lopes 2 collaborations

Daniel J V A Dos Santos 2 collaborations

Elies Molins 2 collaborations

Siham Benramdane 2 collaborations

Joni De Loose 2 collaborations

Nicolò Filippi 2 collaborations

Yentl Van Rymenant 2 collaborations

Koen Augustyns 2 collaborations

Ingrid De Meester 2 collaborations

Pieter Van der Veken 2 collaborations

Lídia M Gonçalves 2 collaborations

Vanda Marques 1 collaboration

Joana D Amaral 1 collaboration

Mattia Mori 1 collaboration

Simona Daniele 1 collaboration

Rebecca Piccarducci 1 collaboration

Elisa Zappelli 1 collaboration

Claudia Martini 1 collaboration

Cecília M P Rodrigues 1 collaboration

Lucía Viejo 1 collaboration

Ricardo M R M Lopes 1 collaboration

Clara Herrera-Arozamena 1 collaboration

Lídia Gonçalves 1 collaboration

María Isabel Rodríguez-Franco 1 collaboration

Cristóbal de Los Ríos 1 collaboration

Luís R Raposo 1 collaboration

Ana Silva 1 collaboration

Dário Silva 1 collaboration

Catarina Roma-Rodrigues 1 collaboration

Pedro V Baptista 1 collaboration

Alexandra R Fernandes 1 collaboration

Olivier Beyens 1 collaboration

Laura Dirkx 1 collaboration

Murat Bozdag 1 collaboration

Pim-Bart Feijens 1 collaboration

Guy Caljon 1 collaboration

Hans De Winter 1 collaboration

Sam Corthaut 1 collaboration

Sofie Thys 1 collaboration

Emile Verhulst 1 collaboration

Pieter Van Wielendaele 1 collaboration

Isabel Pintelon 1 collaboration

Gábor Girst 1 collaboration

Norbert Kúsz 1 collaboration

Hui-Chun Wang 1 collaboration

Attila Hunyadi 1 collaboration

Valentina Barcherini 1 collaboration

Alexandra M M Antunes 1 collaboration

Hélio L Barros 1 collaboration

Sandra N Pinto 1 collaboration

Ricardo J F Ferreira 1 collaboration

Joana B Loureiro 1 collaboration

Rita Silva 1 collaboration

Lucília Saraiva 1 collaboration

Ermelinda Maçôas 1 collaboration