Tatyana Zvyaga

Affiliations

Department of Metabolism and Pharmacokinetics, Bristol Myers Squibb, Research and Early Discovery, Princeton, New Jersey, USA.

Publications (6)

Pharmacodynamics-based approach for efficacious human dose projection of BMS-986260, a small molecule transforming growth factor beta receptor 1 inhibitor.

Biopharmaceutics & drug disposition

Avec: Karen E Parrish , Jesse Swanson , Lihong Cheng , Emily Luk , Paul Stetsko , James Smalley , Yue-Zhong Shu , Jinwen Huang , Jonathan G Pabalan , Yongnian Sun , Tatyana Zvyaga , Mary Ellen Cvijic , James Burke , Robert Borzilleri , Anwar Murtaza , Karen Augustine , Zheng Yang

Development of BET Inhibitors as Potential Treatments for Cancer: Optimization of Pharmacokinetic Properties.

ACS medicinal chemistry letters

Avec: Matthew D Hill , Haiquan Fang , Derek Norris , George V Delucca , Hong Huang , Mikkel DeBenedetto , Claude Quesnelle , William D Schmitz , John S Tokarski , Steven Sheriff , Chunhong Yan , Caroline Fanslau , Zuzana Haarhoff , Christine Huang , Melissa Kramer , Shilpa Madari , Krista Menard , Laura Monereau , John Morrison , Nirmala Raghavan , Eric E Shields , Jean Simmermacher-Mayer , Michael Sinz , Ching Kim Tye , Richard Westhouse , Chunshan Xie , Haiying Zhang , Lisa Zhang , Tatyana Zvyaga , Francis Lee , Ashvinikumar V Gavai , Andrew P Degnan

Identification and Preclinical Evaluation of the Bicyclic Pyrimidine γ-Secretase Modulator BMS-932481.

ACS medicinal chemistry letters

Avec: Kenneth M Boy , Jason M Guernon , Dmitry S Zuev , Li Xu , Yunhui Zhang , Jianliang Shi , Lawrence R Marcin , Mendi A Higgins , Yong-Jin Wu , Subramaniam Krishnananthan , Jianqing Li , Ashok Trehan , Daniel Smith , Jeremy H Toyn , Jere E Meredith , Catherine R Burton , S Roy Kimura , Tatyana Zvyaga , Xiaoliang Zhuo , Kimberley A Lentz , James E Grace , Rex Denton , John S Morrison , Arvind Mathur , Charles F Albright , Michael K Ahlijanian , Richard E Olson , Lorin A Thompson , John E Macor

Development of BET inhibitors as potential treatments for cancer: A new carboline chemotype.

Bioorganic & medicinal chemistry letters

Avec: Matthew D Hill , Claude Quesnelle , John Tokarski , Haiquan Fang , Carolynn Fanslau , Zuzana Haarhoff , Melissa Kramer , Shilpa Madari , Amy Wiebesiek , John Morrison , Jean Simmermacher-Mayer , Michael Sinz , Richard Westhouse , Chunshan Xie , Jiuqiao Zhao , Lisa Huang , Steven Sheriff , Chunhong Yan , Frank Marsilio , Gerry Everlof , Tatyana Zvyaga , Francis Lee , Ashvinikumar V Gavai , Andrew P Degnan

Structure-based amelioration of PXR transactivation in a novel series of macrocyclic allosteric inhibitors of HIV-1 integrase.

Bioorganic & medicinal chemistry letters

Avec: Prasanna Sivaprakasam , Zhongyu Wang , Nicholas A Meanwell , Javed A Khan , David R Langley , Stephen R Johnson , Guo Li , Annapurna Pendri , Timothy P Connolly , Mian Gao , Daniel M Camac , Cheryl Klakouski , Tatyana Zvyaga , Christopher Cianci , Brian McAuliffe , Bo Ding , Linda Discotto , Mark R Krystal , Susan Jenkins , Kevin M Peese , B Narasimhulu Naidu

Development of BET inhibitors as potential treatments for cancer: A search for structural diversity.

Bioorganic & medicinal chemistry letters

Avec: Matthew D Hill , Haiquan Fang , John Tokarski , Carolynn Fanslau , Zuzana Haarhoff , Christine Huang , Melissa Kramer , Krista Menard , Laura Monereau , John Morrison , Asoka Ranasinghe , Eric E Shields , Ching Kim Tye , Richard Westhouse , Gerry Everlof , Steven Sheriff , Chunhong Yan , Frank Marsilio , Lisa Zhang , Tatyana Zvyaga , Francis Lee , Ashvinikumar V Gavai , Andrew P Degnan

Réseau de co-auteurs

Matthew D Hill 3 collaborations

Haiquan Fang 3 collaborations

Steven Sheriff 3 collaborations

Chunhong Yan 3 collaborations

Zuzana Haarhoff 3 collaborations

Melissa Kramer 3 collaborations

John Morrison 3 collaborations

Richard Westhouse 3 collaborations

Francis Lee 3 collaborations

Ashvinikumar V Gavai 3 collaborations

Andrew P Degnan 3 collaborations

Claude Quesnelle 2 collaborations

Christine Huang 2 collaborations

Shilpa Madari 2 collaborations

Krista Menard 2 collaborations

Laura Monereau 2 collaborations

Eric E Shields 2 collaborations

Jean Simmermacher-Mayer 2 collaborations

Michael Sinz 2 collaborations

Ching Kim Tye 2 collaborations

Chunshan Xie 2 collaborations

Lisa Zhang 2 collaborations

John Tokarski 2 collaborations

Carolynn Fanslau 2 collaborations

Frank Marsilio 2 collaborations

Gerry Everlof 2 collaborations

Karen E Parrish 1 collaboration

Jesse Swanson 1 collaboration

Lihong Cheng 1 collaboration

Emily Luk 1 collaboration

Paul Stetsko 1 collaboration

James Smalley 1 collaboration

Yue-Zhong Shu 1 collaboration

Jinwen Huang 1 collaboration

Jonathan G Pabalan 1 collaboration

Yongnian Sun 1 collaboration

Mary Ellen Cvijic 1 collaboration

James Burke 1 collaboration

Robert Borzilleri 1 collaboration

Anwar Murtaza 1 collaboration

Karen Augustine 1 collaboration

Zheng Yang 1 collaboration

Derek Norris 1 collaboration

George V Delucca 1 collaboration

Hong Huang 1 collaboration

Mikkel DeBenedetto 1 collaboration

William D Schmitz 1 collaboration

John S Tokarski 1 collaboration

Caroline Fanslau 1 collaboration

Nirmala Raghavan 1 collaboration

Haiying Zhang 1 collaboration

Kenneth M Boy 1 collaboration

Jason M Guernon 1 collaboration

Dmitry S Zuev 1 collaboration

Li Xu 1 collaboration

Yunhui Zhang 1 collaboration

Jianliang Shi 1 collaboration

Lawrence R Marcin 1 collaboration

Mendi A Higgins 1 collaboration

Yong-Jin Wu 1 collaboration

Subramaniam Krishnananthan 1 collaboration

Jianqing Li 1 collaboration

Ashok Trehan 1 collaboration

Daniel Smith 1 collaboration

Jeremy H Toyn 1 collaboration

Jere E Meredith 1 collaboration

Catherine R Burton 1 collaboration

S Roy Kimura 1 collaboration

Xiaoliang Zhuo 1 collaboration

Kimberley A Lentz 1 collaboration

James E Grace 1 collaboration

Rex Denton 1 collaboration

John S Morrison 1 collaboration

Arvind Mathur 1 collaboration

Charles F Albright 1 collaboration

Michael K Ahlijanian 1 collaboration

Richard E Olson 1 collaboration

Lorin A Thompson 1 collaboration

John E Macor 1 collaboration

Amy Wiebesiek 1 collaboration

Jiuqiao Zhao 1 collaboration

Lisa Huang 1 collaboration

Prasanna Sivaprakasam 1 collaboration

Zhongyu Wang 1 collaboration

Nicholas A Meanwell 1 collaboration

Javed A Khan 1 collaboration

David R Langley 1 collaboration

Stephen R Johnson 1 collaboration

Guo Li 1 collaboration

Annapurna Pendri 1 collaboration

Timothy P Connolly 1 collaboration

Mian Gao 1 collaboration

Daniel M Camac 1 collaboration

Cheryl Klakouski 1 collaboration

Christopher Cianci 1 collaboration

Brian McAuliffe 1 collaboration

Bo Ding 1 collaboration

Linda Discotto 1 collaboration

Mark R Krystal 1 collaboration

Susan Jenkins 1 collaboration

Kevin M Peese 1 collaboration

B Narasimhulu Naidu 1 collaboration

Asoka Ranasinghe 1 collaboration