Michael Sheaff

Affiliations

Department of Histopathology, Pathology and Pharmacy Building, Barts Health NHS Trust, Royal London Hospital, London, United Kingdom.

Publications (22)

Expansion Phase 1 Study of Pegargiminase Plus Pemetrexed and Cisplatin in Patients With Argininosuccinate Synthetase 1-Deficient Mesothelioma: Safety, Efficacy, and Resistance Mechanisms.

JTO clinical and research reports

Avec: Peter W Szlosarek , Melissa M Phillips , Iuliia Pavlyk , Jeremy Steele , Jonathan Shamash , James Spicer , Sanjeev Kumar , Simon Pacey , Xiaoxing Feng , Amanda Johnston , John Bomalaski , Graeme Moir , Kelvin Lau , Stephen Ellis , Michael Sheaff

Thrombotic microangiopathy in untreated myeloma patients receiving carfilzomib, cyclophosphamide and dexamethasone on the CARDAMON study.

British journal of haematology

Avec: Marquita Camilleri , Maria Cuadrado , Elizabeth Phillips , William Wilson , Richard Jenner , Gavin Pang , Sumaiya Kamora , Matthew Streetly , Rakesh Popat , Ceri Bygrave , Roger Owen , James Cavenagh , Mike Chapman , Jonathan Sive , Lydia Eccersley , Michael Sheaff , Reuben Benjamin , Karthik Ramasamy , Gordon Cook , Andres Virchis , Selina J Chavda , Laura Clifton-Hadley , Marie Anne Scully , Kwee Yong

Active symptom control with or without oral vinorelbine in patients with relapsed malignant pleural mesothelioma (VIM): A randomised, phase 2 trial.

EClinicalMedicine

Avec: Dean A Fennell , Catharine Porter , Jason Lester , Sarah Danson , Paul Taylor , Michael Sheaff , Robin M Rudd , Aarti Gaba , Sara Busacca , Lisette Nixon , Georgina Gardner , Liz Darlison , Charlotte Poile , Cathy Richards , Peter-Wells Jordan , Gareth Griffiths , Angela Casbard

Clinical practice guidelines for the diagnosis and surveillance of BAP1 tumour predisposition syndrome.

European journal of human genetics : EJHG

Avec: Fiona Lalloo , Anju Kulkarni , Cindy Chau , Maartje Nielsen , Michael Sheaff , Jeremy Steele , Remco van Doorn , Karin Wadt , Monica Hamill , Beth Torr , Marc Tischkowitz , Auteur inconnu , Helen Hanson

BRCA1/MAD2L1 Deficiency Disrupts the Spindle Assembly Checkpoint to Confer Vinorelbine Resistance in Mesothelioma.

Molecular cancer therapeutics

Avec: Sara Busacca , Laura O'Regan , Anita Singh , Annabel J Sharkey , Alan G Dawson , Joanna Dzialo , Aimee Parsons , Neelam Kumar , Laurel M Schunselaar , Naomi Guppy , Apostolos Nakas , Michael Sheaff , Aaron S Mansfield , Sam M Janes , Paul Baas , Andrew M Fry , Dean A Fennell

Lectins in Cervical Screening.

Cancers

Avec: Anita Ww Lim , André A Neves , Sarah Lam Shang Leen , Pierre Lao-Sirieix , Elizabeth Bird-Lieberman , Naveena Singh , Michael Sheaff , Tony Hollingworth , Kevin Brindle , Peter Sasieni

Phase II Study of Arginine Deprivation Therapy With Pegargiminase in Patients With Relapsed Sensitive or Refractory Small-cell Lung Cancer.

Clinical lung cancer

Avec: Peter E Hall , Neal Ready , Amanda Johnston , John S Bomalaski , Ralph R Venhaus , Michael Sheaff , Lee Krug , Peter W Szlosarek

Immunoglobulin G4-related disease presenting with nephrotic syndrome due to minimal change disease: a case report.

Journal of medical case reports

Avec: Amy Needleman , Michael Sheaff , Ruth J Pepper , Rhys D R Evans

BAP1 loss induces mitotic defects in mesothelioma cells through BRCA1-dependent and independent mechanisms.

Oncogene

Avec: Anita Singh , Sara Busacca , Aarti Gaba , Michael Sheaff , Charlotte Poile , Apostolos Nakas , Joanna Dzialo , Aleksandra Bzura , Alan G Dawson , Dean A Fennell , Andrew M Fry

Pegargiminase Plus First-Line Chemotherapy in Patients With Nonepithelioid Pleural Mesothelioma: The ATOMIC-Meso Randomized Clinical Trial.

JAMA oncology

Avec: Peter W Szlosarek , Benjamin C Creelan , Thomas Sarkodie , Luke Nolan , Paul Taylor , Olga Olevsky , Federica Grosso , Diego Cortinovis , Meenali Chitnis , Amy Roy , David Gilligan , Hedy Kindler , Dionysis Papadatos-Pastos , Giovanni L Ceresoli , Aaron S Mansfield , Anne Tsao , Kenneth J O'Byrne , Anna K Nowak , Jeremy Steele , Michael Sheaff , Chiung-Fang Shiu , Chih-Ling Kuo , Amanda Johnston , John Bomalaski , Marjorie G Zauderer , Dean A Fennell , Auteur inconnu

A Phase I Study of Pegylated Arginine Deiminase (Pegargiminase), Cisplatin, and Pemetrexed in Argininosuccinate Synthetase 1-Deficient Recurrent High-grade Glioma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Peter E Hall , Rachel Lewis , Nelofer Syed , Richard Shaffer , Jane Evanson , Stephen Ellis , Matthew Williams , Xiaoxing Feng , Amanda Johnston , Jim A Thomson , Fiona P Harris , Raj Jena , Tomasz Matys , Sarah Jefferies , Kate Smith , Bor-Wen Wu , John S Bomalaski , Timothy Crook , Kevin O'Neill , Dimitris Paraskevopoulos , Ramsay S Khadeir , Michael Sheaff , Simon Pacey , Piers N Plowman , Peter W Szlosarek

Impact of Transplant Nephrectomy for Patient Survival Over the Past 15 Years: A Single-Center Study.

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation

Avec: Masaki Muramatsu , Yoji Hyodo , Michael Sheaff , Atsushi Aikawa , Magdi Yaqoob , Carmelo Puliatti

Guidelines for the cytopathologic diagnosis of epithelioid and mixed-type malignant mesothelioma: Complementary statement from the international mesothelioma interest group, also endorsed by the international academy of cytology and the papanicolaou society of cytopathology. A proposal to be applauded and promoted but which requires updating.

Diagnostic cytopathology

Avec: Michael Sheaff

Pneumothorax and Pneumatocoele Formation in a Patient with COVID-19: a Case Report.

SN comprehensive clinical medicine

Avec: P Capleton , W Ricketts , K Lau , S Ellis , M Sheaff , K Giaslakiotis , S Uys , Nairi Tchrakian

Progressive hemispheric atrophy in HIV: A Rasmussen's-like variant of CD8 encephalitis?

Neuropathology and applied neurobiology

Avec: Maria Thom , Graham Warner , Marie Williamson , Simon Limb , Michael Sheaff , Smriti Patodia , Alyma Somani , Atul Kumar , Philippe Gaulard , Homa Adle-Biassette

Guidelines for Pathologic Diagnosis of Mesothelioma.

Archives of pathology & laboratory medicine

Avec: Aliya N Husain , David B Chapel , Richard Attanoos , Mary Beth Beasley , Luka Brcic , Kelly Butnor , Lucian R Chirieac , Andrew Churg , Sanja Dacic , Francoise Galateau-Salle , Kenzo Hiroshima , Yin P Hung , Sonja Klebe , Thomas Krausz , Andras Khoor , Leslie Litzky , Alberto Marchevsky , Kazuki Nabeshima , Andrew G Nicholson , Elizabeth N Pavlisko , Anja C Roden , Victor Roggli , Jennifer L Sauter , Jefree J Schulte , Michael Sheaff , William D Travis , Ming-Sound Tsao , Ann E Walts , Thomas V Colby

Perioperative discordance in mesothelioma cell type after pleurectomy/decortication-a possible detrimental effect of neoadjuvant chemotherapy due to epithelial to mesenchymal transition?

Interdisciplinary cardiovascular and thoracic surgery

Avec: Luigi Ventura , Michelle Lee , Ralitsa Baranowski , Joanne Hargrave , Michael Sheaff , David Waller

Cancer Risk Stratification of Anal Intraepithelial Neoplasia in Human Immunodeficiency Virus-Positive Men by Validated Methylation Markers Associated With Progression to Cancer.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Avec: Ramon P van der Zee , Olivier Richel , Carel J M van Noesel , Iuliana Ciocănea-Teodorescu , Annina P van Splunter , Timo J Ter Braak , Mayura Nathan , Tamzin Cuming , Michael Sheaff , Alexander Kreuter , Chris J L M Meijer , Wim G V Quint , Henry J C de Vries , Jan M Prins , Renske D M Steenbergen

Type II Cryoglobulinaemia causing Monoclonal Gammopathy of Renal Significance.

Acute medicine

Avec: B Mohidin , M Sheaff , R D Wheeler , G Khamba

Surgical excision of a rare cardiac tumor: Cardiac hibernoma.

Journal of cardiac surgery

Avec: Michelle Lee , Martin T Yates , Alina-Adriana Mistirian , Michael Sheaff , David Lawrence

Phase 1, pharmacogenomic, dose-expansion study of pegargiminase plus pemetrexed and cisplatin in patients with ASS1-deficient non-squamous non-small cell lung cancer.

Cancer medicine

Avec: Peter W Szlosarek , Akhila G Wimalasingham , Melissa M Phillips , Peter E Hall , Pui Ying Chan , John Conibear , Louise Lim , Sukaina Rashid , Jeremy Steele , Paula Wells , Chiung-Fang Shiu , Chih-Ling Kuo , Xiaoxing Feng , Amanda Johnston , John Bomalaski , Stephen Ellis , Marianne Grantham , Michael Sheaff

A role for macrophages under cytokine control in mediating resistance to ADI-PEG20 (pegargiminase) in ASS1-deficient mesothelioma.

Pharmacological reports : PR

Avec: Melissa M Phillips , Iuliia Pavlyk , Michael Allen , Essam Ghazaly , Rosalind Cutts , Josephine Carpentier , Joe Scott Berry , Callum Nattress , Shenghui Feng , Gunnel Hallden , Claude Chelala , John Bomalaski , Jeremy Steele , Michael Sheaff , Frances Balkwill , Peter W Szlosarek

Réseau de co-auteurs

Peter W Szlosarek 6 collaborations

Jeremy Steele 5 collaborations

Amanda Johnston 5 collaborations

John Bomalaski 4 collaborations

Dean A Fennell 4 collaborations

Melissa M Phillips 3 collaborations

Xiaoxing Feng 3 collaborations

Stephen Ellis 3 collaborations

Sara Busacca 3 collaborations

Peter E Hall 3 collaborations

Iuliia Pavlyk 2 collaborations

Simon Pacey 2 collaborations

Paul Taylor 2 collaborations

Aarti Gaba 2 collaborations

Charlotte Poile 2 collaborations

None None 2 collaborations

Anita Singh 2 collaborations

Alan G Dawson 2 collaborations

Joanna Dzialo 2 collaborations

Apostolos Nakas 2 collaborations

Aaron S Mansfield 2 collaborations

Andrew M Fry 2 collaborations

John S Bomalaski 2 collaborations

Chiung-Fang Shiu 2 collaborations

Chih-Ling Kuo 2 collaborations

M Sheaff 2 collaborations

Michelle Lee 2 collaborations

Jonathan Shamash 1 collaboration

James Spicer 1 collaboration

Sanjeev Kumar 1 collaboration

Graeme Moir 1 collaboration

Kelvin Lau 1 collaboration

Marquita Camilleri 1 collaboration

Maria Cuadrado 1 collaboration

Elizabeth Phillips 1 collaboration

William Wilson 1 collaboration

Richard Jenner 1 collaboration

Gavin Pang 1 collaboration

Sumaiya Kamora 1 collaboration

Matthew Streetly 1 collaboration

Rakesh Popat 1 collaboration

Ceri Bygrave 1 collaboration

Roger Owen 1 collaboration

James Cavenagh 1 collaboration

Mike Chapman 1 collaboration

Jonathan Sive 1 collaboration

Lydia Eccersley 1 collaboration

Reuben Benjamin 1 collaboration

Karthik Ramasamy 1 collaboration

Gordon Cook 1 collaboration

Andres Virchis 1 collaboration

Selina J Chavda 1 collaboration

Laura Clifton-Hadley 1 collaboration

Marie Anne Scully 1 collaboration

Kwee Yong 1 collaboration

Catharine Porter 1 collaboration

Jason Lester 1 collaboration

Sarah Danson 1 collaboration

Robin M Rudd 1 collaboration

Lisette Nixon 1 collaboration

Georgina Gardner 1 collaboration

Liz Darlison 1 collaboration

Cathy Richards 1 collaboration

Peter-Wells Jordan 1 collaboration

Gareth Griffiths 1 collaboration

Angela Casbard 1 collaboration

Fiona Lalloo 1 collaboration

Anju Kulkarni 1 collaboration

Cindy Chau 1 collaboration

Maartje Nielsen 1 collaboration

Remco van Doorn 1 collaboration

Karin Wadt 1 collaboration

Monica Hamill 1 collaboration

Beth Torr 1 collaboration

Marc Tischkowitz 1 collaboration

Helen Hanson 1 collaboration

Laura O'Regan 1 collaboration

Annabel J Sharkey 1 collaboration

Aimee Parsons 1 collaboration

Neelam Kumar 1 collaboration

Laurel M Schunselaar 1 collaboration

Naomi Guppy 1 collaboration

Sam M Janes 1 collaboration

Paul Baas 1 collaboration

Anita Ww Lim 1 collaboration

André A Neves 1 collaboration

Sarah Lam Shang Leen 1 collaboration

Pierre Lao-Sirieix 1 collaboration

Elizabeth Bird-Lieberman 1 collaboration

Naveena Singh 1 collaboration

Tony Hollingworth 1 collaboration

Kevin Brindle 1 collaboration

Peter Sasieni 1 collaboration

Neal Ready 1 collaboration

Ralph R Venhaus 1 collaboration

Lee Krug 1 collaboration

Amy Needleman 1 collaboration

Ruth J Pepper 1 collaboration

Rhys D R Evans 1 collaboration

Aleksandra Bzura 1 collaboration

Benjamin C Creelan 1 collaboration

Thomas Sarkodie 1 collaboration

Luke Nolan 1 collaboration

Olga Olevsky 1 collaboration

Federica Grosso 1 collaboration

Diego Cortinovis 1 collaboration

Meenali Chitnis 1 collaboration

Amy Roy 1 collaboration

David Gilligan 1 collaboration

Hedy Kindler 1 collaboration

Dionysis Papadatos-Pastos 1 collaboration

Giovanni L Ceresoli 1 collaboration

Anne Tsao 1 collaboration

Kenneth J O'Byrne 1 collaboration

Anna K Nowak 1 collaboration

Marjorie G Zauderer 1 collaboration

Rachel Lewis 1 collaboration

Nelofer Syed 1 collaboration

Richard Shaffer 1 collaboration

Jane Evanson 1 collaboration

Matthew Williams 1 collaboration

Jim A Thomson 1 collaboration

Fiona P Harris 1 collaboration

Raj Jena 1 collaboration

Tomasz Matys 1 collaboration

Sarah Jefferies 1 collaboration

Kate Smith 1 collaboration

Bor-Wen Wu 1 collaboration

Timothy Crook 1 collaboration

Kevin O'Neill 1 collaboration

Dimitris Paraskevopoulos 1 collaboration

Ramsay S Khadeir 1 collaboration

Piers N Plowman 1 collaboration

Masaki Muramatsu 1 collaboration

Yoji Hyodo 1 collaboration

Atsushi Aikawa 1 collaboration

Magdi Yaqoob 1 collaboration

Carmelo Puliatti 1 collaboration

P Capleton 1 collaboration

W Ricketts 1 collaboration

K Lau 1 collaboration

S Ellis 1 collaboration

K Giaslakiotis 1 collaboration

S Uys 1 collaboration

Nairi Tchrakian 1 collaboration

Maria Thom 1 collaboration

Graham Warner 1 collaboration

Marie Williamson 1 collaboration

Simon Limb 1 collaboration

Smriti Patodia 1 collaboration

Alyma Somani 1 collaboration

Atul Kumar 1 collaboration

Philippe Gaulard 1 collaboration

Homa Adle-Biassette 1 collaboration

Aliya N Husain 1 collaboration

David B Chapel 1 collaboration

Richard Attanoos 1 collaboration

Mary Beth Beasley 1 collaboration

Luka Brcic 1 collaboration

Kelly Butnor 1 collaboration

Lucian R Chirieac 1 collaboration

Andrew Churg 1 collaboration

Sanja Dacic 1 collaboration

Francoise Galateau-Salle 1 collaboration

Kenzo Hiroshima 1 collaboration

Yin P Hung 1 collaboration

Sonja Klebe 1 collaboration

Thomas Krausz 1 collaboration

Andras Khoor 1 collaboration

Leslie Litzky 1 collaboration

Alberto Marchevsky 1 collaboration

Kazuki Nabeshima 1 collaboration

Andrew G Nicholson 1 collaboration

Elizabeth N Pavlisko 1 collaboration

Anja C Roden 1 collaboration

Victor Roggli 1 collaboration

Jennifer L Sauter 1 collaboration

Jefree J Schulte 1 collaboration

William D Travis 1 collaboration

Ming-Sound Tsao 1 collaboration

Ann E Walts 1 collaboration

Thomas V Colby 1 collaboration

Luigi Ventura 1 collaboration

Ralitsa Baranowski 1 collaboration

Joanne Hargrave 1 collaboration

David Waller 1 collaboration

Ramon P van der Zee 1 collaboration

Olivier Richel 1 collaboration

Carel J M van Noesel 1 collaboration

Iuliana Ciocănea-Teodorescu 1 collaboration

Annina P van Splunter 1 collaboration

Timo J Ter Braak 1 collaboration

Mayura Nathan 1 collaboration

Tamzin Cuming 1 collaboration

Alexander Kreuter 1 collaboration

Chris J L M Meijer 1 collaboration

Wim G V Quint 1 collaboration

Henry J C de Vries 1 collaboration

Jan M Prins 1 collaboration

Renske D M Steenbergen 1 collaboration

B Mohidin 1 collaboration

R D Wheeler 1 collaboration

G Khamba 1 collaboration

Martin T Yates 1 collaboration

Alina-Adriana Mistirian 1 collaboration

David Lawrence 1 collaboration

Akhila G Wimalasingham 1 collaboration

Pui Ying Chan 1 collaboration

John Conibear 1 collaboration

Louise Lim 1 collaboration

Sukaina Rashid 1 collaboration

Paula Wells 1 collaboration

Marianne Grantham 1 collaboration

Michael Allen 1 collaboration

Essam Ghazaly 1 collaboration

Rosalind Cutts 1 collaboration

Josephine Carpentier 1 collaboration

Joe Scott Berry 1 collaboration

Callum Nattress 1 collaboration

Shenghui Feng 1 collaboration

Gunnel Hallden 1 collaboration

Claude Chelala 1 collaboration

Frances Balkwill 1 collaboration