Masanori Nakakariya

Affiliations

Global Drug Metabolism and Pharmacokinetics, Takeda Development Center Americas, Inc. (TDCA), 9625 Towne Centre Drive, San Diego, California 92121, United States.

Publications (12)

Interlaboratory Variability in the Madin-Darby Canine Kidney Cell Proteome.

Molecular pharmaceutics

Avec: Matthew D Harwood , Katharina Zettl , Manuel Weinheimer , Venkatesh Pilla-Reddy , Hong Shen , Frank Jacobs , Xiaoyan Chu , Felix Huth , Masanori Nakakariya , Paresh P Chothe , Sibylle Neuhoff , Jacek R Wiśniewski

DNA/RNA heteroduplex technology with cationic oligopeptide reduces class-related adverse effects of nucleic acid drugs.

Molecular therapy. Nucleic acids

Avec: Masahiro Ohara , Tetsuya Nagata , Rintaro Iwata Hara , Kie Yoshida-Tanaka , Nozomi Toide , Kazunori Takagi , Kazuki Sato , Tomoya Takenaka , Masanori Nakakariya , Kenichi Miyata , Yusuke Maeda , Kazuko Toh , Takeshi Wada , Takanori Yokota

Physiologically-Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug-Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations.

Clinical pharmacology and therapeutics

Avec: Kunal S Taskar , Venkatesh Pilla Reddy , Howard Burt , Maria M Posada , Manthena Varma , Ming Zheng , Mohammed Ullah , Arian Emami Riedmaier , Ken-Ichi Umehara , Jan Snoeys , Masanori Nakakariya , Xiaoyan Chu , Maud Beneton , Yuan Chen , Felix Huth , Rangaraj Narayanan , Dwaipayan Mukherjee , Vaishali Dixit , Yuichi Sugiyama , Sibylle Neuhoff

Drug Transporters in Drug Disposition - Highlights from the Year 2023.

Drug metabolism reviews

Avec: Paresh P Chothe , Upendra A Argikar , Pallabi Mitra , Masanori Nakakariya , Diane Ramsden , Charles J Rotter , Philip Sandoval , Kimio Tohyama

TAK-861, a potent, orally available orexin receptor 2-selective agonist, produces wakefulness in monkeys and improves narcolepsy-like phenotypes in mouse models.

Scientific reports

Avec: Kayo Mitsukawa , Michiko Terada , Ryuji Yamada , Taku Monjo , Tetsuaki Hiyoshi , Masanori Nakakariya , Yuichi Kajita , Tatsuya Ando , Tatsuki Koike , Haruhide Kimura

Involvement of Proton-Coupled Organic Cation Antiporter in Human Blood-Brain Barrier Transport of Mesoridazine and Metoclopramide.

Biological & pharmaceutical bulletin

Avec: Yasuyuki Debori , Tomoko Igari , Masanori Nakakariya , Hideki Hirabayashi , Kazunobu Aoyama , Nobuyuki Amano , Toshiki Kurosawa , Yoshiyuki Kubo , Yoshiharu Deguchi

Inhibition of MGAT2 modulates fat-induced gut peptide release and fat intake in normal mice and ameliorates obesity and diabetes in ob/ob mice fed on a high-fat diet.

FEBS open bio

Avec: Taisuke Mochida , Kazumi Take , Toshiyuki Maki , Masanori Nakakariya , Ryutaro Adachi , Kenjiro Sato , Tomoyuki Kitazaki , Shiro Takekawa

Orexin receptor 2 agonist activates diaphragm and genioglossus muscle through stimulating inspiratory neurons in the pre-Bötzinger complex, and phrenic and hypoglossal motoneurons in rodents.

PloS one

Avec: Ryuji Yamada , Tatsuki Koike , Masanori Nakakariya , Haruhide Kimura

Drug transporters in drug disposition - the year 2022 in review.

Drug metabolism reviews

Avec: Paresh P Chothe , Pallabi Mitra , Masanori Nakakariya , Diane Ramsden , Charles J Rotter , Philip Sandoval , Kimio Tohyama

Discovery of 1,8-naphthyridin-2-one derivative as a potent and selective sphingomyelin synthase 2 inhibitor.

Bioorganic & medicinal chemistry

Avec: Takafumi Yukawa , Takashi Nakahata , Rei Okamoto , Yuji Ishichi , Yasufumi Miyamoto , Satoshi Nishimura , Tatsuo Oikawa , Kazuki Kubo , Ryutaro Adachi , Yoshinori Satomi , Masanori Nakakariya , Nobuyuki Amano , Masahiro Kamaura , Nobuyuki Matsunaga

Novel insights in drug transporter sciences: the year 2021 in review.

Drug metabolism reviews

Avec: Paresh P Chothe , Pallabi Mitra , Masanori Nakakariya , Diane Ramsden , Charles J Rotter , Philip Sandoval , Kimio Tohyama

Effects of an OX2R agonist on migration and removal of tau from mouse brain.

Scientific reports

Avec: Michiko Terada , Kayo Mitsukawa , Masanori Nakakariya , Tatsuki Koike , Haruhide Kimura

Réseau de co-auteurs

Paresh P Chothe 4 collaborations

Pallabi Mitra 3 collaborations

Diane Ramsden 3 collaborations

Charles J Rotter 3 collaborations

Philip Sandoval 3 collaborations

Kimio Tohyama 3 collaborations

Tatsuki Koike 3 collaborations

Haruhide Kimura 3 collaborations

Xiaoyan Chu 2 collaborations

Felix Huth 2 collaborations

Sibylle Neuhoff 2 collaborations

Kayo Mitsukawa 2 collaborations

Michiko Terada 2 collaborations

Ryuji Yamada 2 collaborations

Nobuyuki Amano 2 collaborations

Ryutaro Adachi 2 collaborations

Matthew D Harwood 1 collaboration

Katharina Zettl 1 collaboration

Manuel Weinheimer 1 collaboration

Venkatesh Pilla-Reddy 1 collaboration

Hong Shen 1 collaboration

Frank Jacobs 1 collaboration

Jacek R Wiśniewski 1 collaboration

Masahiro Ohara 1 collaboration

Tetsuya Nagata 1 collaboration

Rintaro Iwata Hara 1 collaboration

Kie Yoshida-Tanaka 1 collaboration

Nozomi Toide 1 collaboration

Kazunori Takagi 1 collaboration

Kazuki Sato 1 collaboration

Tomoya Takenaka 1 collaboration

Kenichi Miyata 1 collaboration

Yusuke Maeda 1 collaboration

Kazuko Toh 1 collaboration

Takeshi Wada 1 collaboration

Takanori Yokota 1 collaboration

Kunal S Taskar 1 collaboration

Venkatesh Pilla Reddy 1 collaboration

Howard Burt 1 collaboration

Maria M Posada 1 collaboration

Manthena Varma 1 collaboration

Ming Zheng 1 collaboration

Mohammed Ullah 1 collaboration

Arian Emami Riedmaier 1 collaboration

Ken-Ichi Umehara 1 collaboration

Jan Snoeys 1 collaboration

Maud Beneton 1 collaboration

Yuan Chen 1 collaboration

Rangaraj Narayanan 1 collaboration

Dwaipayan Mukherjee 1 collaboration

Vaishali Dixit 1 collaboration

Yuichi Sugiyama 1 collaboration

Upendra A Argikar 1 collaboration

Taku Monjo 1 collaboration

Tetsuaki Hiyoshi 1 collaboration

Yuichi Kajita 1 collaboration

Tatsuya Ando 1 collaboration

Yasuyuki Debori 1 collaboration

Tomoko Igari 1 collaboration

Hideki Hirabayashi 1 collaboration

Kazunobu Aoyama 1 collaboration

Toshiki Kurosawa 1 collaboration

Yoshiyuki Kubo 1 collaboration

Yoshiharu Deguchi 1 collaboration

Taisuke Mochida 1 collaboration

Kazumi Take 1 collaboration

Toshiyuki Maki 1 collaboration

Kenjiro Sato 1 collaboration

Tomoyuki Kitazaki 1 collaboration

Shiro Takekawa 1 collaboration

Takafumi Yukawa 1 collaboration

Takashi Nakahata 1 collaboration

Rei Okamoto 1 collaboration

Yuji Ishichi 1 collaboration

Yasufumi Miyamoto 1 collaboration

Satoshi Nishimura 1 collaboration

Tatsuo Oikawa 1 collaboration

Kazuki Kubo 1 collaboration

Yoshinori Satomi 1 collaboration

Masahiro Kamaura 1 collaboration

Nobuyuki Matsunaga 1 collaboration