Mark Jedrychowski

Affiliations

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Cell Biology, Harvard Medical School, Boston, MA, USA.

Publications (13)

Tetracyclines promote survival and fitness in mitochondrial disease models.

Nature metabolism

Avec: Elizabeth A Perry , Christopher F Bennett , Chi Luo , Eduardo Balsa , Mark Jedrychowski , Katherine E O'Malley , Pedro Latorre-Muro , Richard Porter Ladley , Kamar Reda , Peter M Wright , Steven P Gygi , Andrew G Myers , Pere Puigserver

Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly.

Nature chemical biology

Avec: Christopher F Bennett , Katherine E O'Malley , Elizabeth A Perry , Eduardo Balsa , Pedro Latorre-Muro , Christopher L Riley , Chi Luo , Mark Jedrychowski , Steven P Gygi , Pere Puigserver

Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death.

Nature communications

Avec: Eduardo Balsa , Elizabeth A Perry , Christopher F Bennett , Mark Jedrychowski , Steven P Gygi , John G Doench , Pere Puigserver

ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2α Axis.

Molecular cell

Avec: Eduardo Balsa , Meghan S Soustek , Ajith Thomas , Sara Cogliati , Carolina García-Poyatos , Elena Martín-García , Mark Jedrychowski , Steve P Gygi , José Antonio Enriquez , Pere Puigserver

IRF3 reduces adipose thermogenesis via ISG15-mediated reprogramming of glycolysis.

The Journal of clinical investigation

Avec: Shuai Yan , Manju Kumari , Haopeng Xiao , Christopher Jacobs , Shihab Kochumon , Mark Jedrychowski , Edward Chouchani , Rasheed Ahmad , Evan D Rosen

Short-chain fatty acids in the saliva of patients with gastroesophageal reflux disease.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society

Avec: K Szczeklik , W Krzysciak , M Osiewicz , B Bystrowska , M Kuszaj , A Piatek-Guziewicz , M Jedrychowski , B Brzozowski , D Cibor , D Owczarek , J Pytko-Polonczyk , M Zwolinska-Wcislo

Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer's disease.

Nature neuroscience

Avec: Zhuoran Yin , Shawn Herron , Sebastian Silveira , Kilian Kleemann , Christian Gauthier , Dania Mallah , Yiran Cheng , Milica A Margeta , Kristen M Pitts , Jen-Li Barry , Ayshwarya Subramanian , Hannah Shorey , Wesley Brandao , Ana Durao , Jean-Christophe Delpech , Charlotte Madore , Mark Jedrychowski , Amrendra K Ajay , Gopal Murugaiyan , Samuel W Hersh , Seiko Ikezu , Tsuneya Ikezu , Oleg Butovsky

Liver mitochondrial cristae organizing protein MIC19 promotes energy expenditure and pedestrian locomotion by altering nucleotide metabolism.

Cell metabolism

Avec: Jee Hyung Sohn , Beste Mutlu , Pedro Latorre-Muro , Jiaxin Liang , Christopher F Bennett , Kfir Sharabi , Noa Kantorovich , Mark Jedrychowski , Steven P Gygi , Alexander S Banks , Pere Puigserver

An Evolutionarily Conserved uORF Regulates PGC1α and Oxidative Metabolism in Mice, Flies, and Bluefin Tuna.

Cell metabolism

Avec: Phillip A Dumesic , Daniel F Egan , Philipp Gut , Mei T Tran , Alice Parisi , Nirmalya Chatterjee , Mark Jedrychowski , Margherita Paschini , Lawrence Kazak , Sarah E Wilensky , Florence Dou , Dina Bogoslavski , Jeffrey A Cartier , Norbert Perrimon , Shingo Kajimura , Samir M Parikh , Bruce M Spiegelman

Quantitative Proteomics of the Cancer Cell Line Encyclopedia.

Cell

Avec: David P Nusinow , John Szpyt , Mahmoud Ghandi , Christopher M Rose , E Robert McDonald , Marian Kalocsay , Judit Jané-Valbuena , Ellen Gelfand , Devin K Schweppe , Mark Jedrychowski , Javad Golji , Dale A Porter , Tomas Rejtar , Y Karen Wang , Gregory V Kryukov , Frank Stegmeier , Brian K Erickson , Levi A Garraway , William R Sellers , Steven P Gygi

A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation.

Cell metabolism

Avec: Pedro Latorre-Muro , Katherine E O'Malley , Christopher F Bennett , Elizabeth A Perry , Eduardo Balsa , Clint D J Tavares , Mark Jedrychowski , Steven P Gygi , Pere Puigserver

Epigenetic suppression of PGC1α (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas.

Nature communications

Avec: Jiaxin Liang , Deyang Yu , Chi Luo , Christopher Bennett , Mark Jedrychowski , Steve P Gygi , Hans R Widlund , Pere Puigserver

Selective Mitochondrial Respiratory Complex I Subunit Deficiency Causes Tumor Immunogenicity.

bioRxiv : the preprint server for biology

Avec: Jiaxin Liang , Tevis Vitale , Xixi Zhang , Thomas D Jackson , Deyang Yu , Mark Jedrychowski , Steve P Gygi , Hans R Widlund , Kai W Wucherpfennig , Pere Puigserver

Réseau de co-auteurs

Pere Puigserver 8 collaborations

Steven P Gygi 6 collaborations

Christopher F Bennett 5 collaborations

Eduardo Balsa 5 collaborations

Elizabeth A Perry 4 collaborations

Pedro Latorre-Muro 4 collaborations

Chi Luo 3 collaborations

Katherine E O'Malley 3 collaborations

Steve P Gygi 3 collaborations

Jiaxin Liang 3 collaborations

Deyang Yu 2 collaborations

Hans R Widlund 2 collaborations

Richard Porter Ladley 1 collaboration

Kamar Reda 1 collaboration

Peter M Wright 1 collaboration

Andrew G Myers 1 collaboration

Christopher L Riley 1 collaboration

John G Doench 1 collaboration

Meghan S Soustek 1 collaboration

Ajith Thomas 1 collaboration

Sara Cogliati 1 collaboration

Carolina García-Poyatos 1 collaboration

Elena Martín-García 1 collaboration

José Antonio Enriquez 1 collaboration

Shuai Yan 1 collaboration

Manju Kumari 1 collaboration

Haopeng Xiao 1 collaboration

Christopher Jacobs 1 collaboration

Shihab Kochumon 1 collaboration

Edward Chouchani 1 collaboration

Rasheed Ahmad 1 collaboration

Evan D Rosen 1 collaboration

K Szczeklik 1 collaboration

W Krzysciak 1 collaboration

M Osiewicz 1 collaboration

B Bystrowska 1 collaboration

M Kuszaj 1 collaboration

A Piatek-Guziewicz 1 collaboration

M Jedrychowski 1 collaboration

B Brzozowski 1 collaboration

D Cibor 1 collaboration

D Owczarek 1 collaboration

J Pytko-Polonczyk 1 collaboration

M Zwolinska-Wcislo 1 collaboration

Zhuoran Yin 1 collaboration

Shawn Herron 1 collaboration

Sebastian Silveira 1 collaboration

Kilian Kleemann 1 collaboration

Christian Gauthier 1 collaboration

Dania Mallah 1 collaboration

Yiran Cheng 1 collaboration

Milica A Margeta 1 collaboration

Kristen M Pitts 1 collaboration

Jen-Li Barry 1 collaboration

Ayshwarya Subramanian 1 collaboration

Hannah Shorey 1 collaboration

Wesley Brandao 1 collaboration

Ana Durao 1 collaboration

Jean-Christophe Delpech 1 collaboration

Charlotte Madore 1 collaboration

Amrendra K Ajay 1 collaboration

Gopal Murugaiyan 1 collaboration

Samuel W Hersh 1 collaboration

Seiko Ikezu 1 collaboration

Tsuneya Ikezu 1 collaboration

Oleg Butovsky 1 collaboration

Jee Hyung Sohn 1 collaboration

Beste Mutlu 1 collaboration

Kfir Sharabi 1 collaboration

Noa Kantorovich 1 collaboration

Alexander S Banks 1 collaboration

Phillip A Dumesic 1 collaboration

Daniel F Egan 1 collaboration

Philipp Gut 1 collaboration

Mei T Tran 1 collaboration

Alice Parisi 1 collaboration

Nirmalya Chatterjee 1 collaboration

Margherita Paschini 1 collaboration

Lawrence Kazak 1 collaboration

Sarah E Wilensky 1 collaboration

Florence Dou 1 collaboration

Dina Bogoslavski 1 collaboration

Jeffrey A Cartier 1 collaboration

Norbert Perrimon 1 collaboration

Shingo Kajimura 1 collaboration

Samir M Parikh 1 collaboration

Bruce M Spiegelman 1 collaboration

David P Nusinow 1 collaboration

John Szpyt 1 collaboration

Mahmoud Ghandi 1 collaboration

Christopher M Rose 1 collaboration

E Robert McDonald 1 collaboration

Marian Kalocsay 1 collaboration

Judit Jané-Valbuena 1 collaboration

Ellen Gelfand 1 collaboration

Devin K Schweppe 1 collaboration

Javad Golji 1 collaboration

Dale A Porter 1 collaboration

Tomas Rejtar 1 collaboration

Y Karen Wang 1 collaboration

Gregory V Kryukov 1 collaboration

Frank Stegmeier 1 collaboration

Brian K Erickson 1 collaboration

Levi A Garraway 1 collaboration

William R Sellers 1 collaboration

Clint D J Tavares 1 collaboration

Christopher Bennett 1 collaboration

Tevis Vitale 1 collaboration

Xixi Zhang 1 collaboration

Thomas D Jackson 1 collaboration

Kai W Wucherpfennig 1 collaboration