L Maletínská

Publications (40)

Inflammation: major denominator of obesity, Type 2 diabetes and Alzheimer's disease-like pathology?

Clinical science (London, England : 1979)

Avec: Miroslava Kacířová , Anna Zmeškalová , Lucia Kořínková , Blanka Železná , Jaroslav Kuneš , Lenka Maletínská

Mass spectrometry imaging of free-floating brain sections detects pathological lipid distribution in a mouse model of Alzheimer's-like pathology.

The Analyst

Avec: Štěpán Strnad , Veronika PraŽienková , Martina Holubová , David Sýkora , Josef Cvačka , Lenka Maletínská , Blanka Železná , Jaroslav Kuneš , Vladimír Vrkoslav

Sweet taste of heavy water.

Communications biology

Avec: Natalie Ben Abu , Philip E Mason , Hadar Klein , Nitzan Dubovski , Yaron Ben Shoshan-Galeczki , Einav Malach , Veronika Pražienková , Lenka Maletínská , Carmelo Tempra , Victor Cruces Chamorro , Josef Cvačka , Maik Behrens , Masha Y Niv , Pavel Jungwirth

Search for lipidized PrRP analogs with strong anorexigenic effect: In vitro and in vivo studies.

Neuropeptides

Avec: Veronika Strnadová , Alena Karnošová , Miroslava Blechová , Barbora Neprašová , Lucie Holá , Anna Němcová , Aneta Myšková , David Sýkora , Blanka Železná , Jaroslav Kuneš , Lenka Maletínská

Glutathione Levels and Lipid Oxidative Damage in Selected Organs of Obese Koletsky and Lean Spontaneously Hypertensive Rats.

Physiological research

Avec: H Rauchová , B Neprašová , L Maletínská , J Kuneš

Cholecystokinin system is involved in the anorexigenic effect of peripherally applied palmitoylated prolactin-releasing peptide in fasted mice.

Physiological research

Avec: Z Pirník , L Kořínková , J Osacká , B Železná , J Kuneš , L Maletínská

GPR10 gene deletion in mice increases basal neuronal activity, disturbs insulin sensitivity and alters lipid homeostasis.

Gene

Avec: Veronika Pražienková , Jiří Funda , Zdenko Pirník , Alena Karnošová , Lucie Hrubá , Lucia Kořínková , Barbora Neprašová , Petra Janovská , Michal Benzce , Michaela Kadlecová , Jaroslav Blahoš , Jan Kopecký , Blanka Železná , Jaroslav Kuneš , Kristina Bardová , Lenka Maletínská

Palmitoylated prolactin-releasing peptide treatment had neuroprotective but not anti-obesity effect in fa/fa rats with leptin signaling disturbances.

Nutrition & diabetes

Avec: Lucia Mráziková , Silvie Hojná , Andrea Pačesová , Lucie Hrubá , Veronika Strnadová , Barbora Neprašová , Blanka Železná , Jaroslav Kuneš , Lenka Maletínská

Peripheral administration of lipidized NPAF and NPFF analogs does not influence central food intake regulation but induces anxiety-like behavior.

Neuropeptides

Avec: Veronika Strnadová , Alena Morgan , Magdalena Škrlová , Eliška Haasová , Kristina Bardová , Aneta Myšková , David Sýkora , Jaroslav Kuneš , Blanka Železná , Lenka Maletínská

Lipidized PrRP Analog Exhibits Strong Anti-Obesity and Antidiabetic Properties in Old WKY Rats with Obesity and Glucose Intolerance.

Nutrients

Avec: Lucia Mráziková , Silvie Hojná , Petra Vaculová , Štěpán Strnad , Vladimír Vrkoslav , Helena Pelantová , Marek Kuzma , Blanka Železná , Jaroslav Kuneš , Lenka Maletínská

Metabolomic Study of Aging in

Metabolites

Avec: Helena Pelantová , Petra Tomášová , Blanka Šedivá , Barbora Neprašová , Lucia Mráziková , Jaroslav Kuneš , Blanka Železná , Lenka Maletínská , Marek Kuzma

NPFFR2-deficient mice fed a high-fat diet develop strong intolerance to glucose.

Clinical science (London, England : 1979)

Avec: Alena Karnošová , Veronika Strnadová , Blanka Železná , Jaroslav Kuneš , Petr Kašpárek , Lenka Maletínská

Synergistic effect of leptin and lipidized PrRP on metabolic pathways in ob/ob mice.

Journal of molecular endocrinology

Avec: Lucia Kořínková , Martina Holubová , Barbora Neprašová , Lucie Hrubá , Veronika Pražienková , Michal Bencze , Martin Haluzík , Jaroslav Kuneš , Lenka Maletínská , Blanka Železná

Cellular Signaling and Anti-Apoptotic Effects of Prolactin-Releasing Peptide and Its Analog on SH-SY5Y Cells.

International journal of molecular sciences

Avec: Anna Zmeškalová , Andrea Popelová , Aneta Exnerová , Blanka Železná , Jaroslav Kuneš , Lenka Maletínská

Lipidized Prolactin-Releasing Peptide Agonist Attenuates Hypothermia-Induced Tau Hyperphosphorylation in Neurons.

Journal of Alzheimer's disease : JAD

Avec: Veronika Pražienková , Claire Schirmer , Martina Holubová , Blanka Železná , Jaroslav Kuneš , Marie-Christine Galas , Lenka Maletínská

Prolactin-Releasing Peptide: Physiological and Pharmacological Properties.

International journal of molecular sciences

Avec: Veronika Pražienková , Andrea Popelová , Jaroslav Kuneš , Lenka Maletínská

Pathophysiology of NAFLD and NASH in Experimental Models: The Role of Food Intake Regulating Peptides.

Frontiers in endocrinology

Avec: L Kořínková , V Pražienková , L Černá , A Karnošová , B Železná , J Kuneš , Lenka Maletínská

Palmitoylation of Prolactin-Releasing Peptide Increased Affinity for and Activation of the GPR10, NPFF-R2 and NPFF-R1 Receptors: In Vitro Study.

International journal of molecular sciences

Avec: Alena Karnošová , Veronika Strnadová , Lucie Holá , Blanka Železná , Jaroslav Kuneš , Lenka Maletínská

An analogue of the Prolactin Releasing Peptide reduces obesity and promotes adult neurogenesis.

EMBO reports

Avec: Sara Km Jörgensen , Alena Karnošová , Simone Mazzaferro , Oliver Rowley , Hsiao-Jou Cortina Chen , Sarah J Robbins , Sarah Christofides , Florian T Merkle , Lenka Maletínská , David Petrik

Iodination of CART(61-102) peptide: Preserved binding and anorexigenic activity in mice.

Journal of labelled compounds & radiopharmaceuticals

Avec: Veronika Pražienková , Aleš Marek , Lenka Maletínská

Metabolomic Study of Obesity and Its Treatment with Palmitoylated Prolactin-Releasing Peptide Analog in Spontaneously Hypertensive and Normotensive Rats.

Journal of proteome research

Avec: Martina Čermáková , Helena Pelantová , Barbora Neprašová , Blanka Šedivá , Lenka Maletínská , Jaroslav Kuneš , Petra Tomášová , Blanka Železná , Marek Kuzma

Metabolomics Based on MS in Mice with Diet-Induced Obesity and Type 2 Diabetes Mellitus: the Effect of Vildagliptin, Metformin, and Their Combination.

Applied biochemistry and biotechnology

Avec: Petra Tomášová , Martina Bugáňová , Helena Pelantová , Martina Holubová , Blanka Šedivá , Blanka Železná , Martin Haluzík , Lenka Maletínská , Jaroslav Kuneš , Marek Kuzma

Aging and high-fat diet feeding lead to peripheral insulin resistance and sex-dependent changes in brain of mouse model of tau pathology THY-Tau22.

Journal of neuroinflammation

Avec: Miroslava Kacířová , Blanka Železná , Michaela Blažková , Martina Holubová , Andrea Popelová , Jaroslav Kuneš , Blanka Šedivá , Lenka Maletínská

A Novel Truncated Liver Enriched Antimicrobial Peptide-2 Palmitoylated at its N-Terminal Antagonizes Effects of Ghrelin.

The Journal of pharmacology and experimental therapeutics

Avec: Lucie Holá , Blanka Železná , Alena Karnošová , Jaroslav Kuneš , Jean-Alain Fehrentz , Séverine Denoyelle , Sonia Cantel , Miroslava Blechová , David Sýkora , Aneta Myšková , Lenka Maletínská

Feeding High-Fat Diet Accelerates Development of Peripheral and Central Insulin Resistance and Inflammation and Worsens AD-like Pathology in APP/PS1 Mice.

Nutrients

Avec: Anna Mengr , Veronika Strnadová , Štěpán Strnad , Vladimír Vrkoslav , Helena Pelantová , Marek Kuzma , Thomas Comptdaer , Blanka Železná , Jaroslav Kuneš , Marie-Christine Galas , Andrea Pačesová , Lenka Maletínská

Obesity, Cardiovascular and Neurodegenerative Diseases: Potential Common Mechanisms.

Physiological research

Avec: J Kuneš , S Hojná , L Mráziková , A Montezano , R M Touyz , L Maletínská

Lipidization as a tool toward peptide therapeutics.

Drug delivery

Avec: Aneta Myšková , David Sýkora , Jaroslav Kuneš , Lenka Maletínská

Thermal evaporation as sample preparation for silver-assisted laser desorption/ionization mass spectrometry imaging of cholesterol in amyloid tissues.

The Analyst

Avec: Štěpán Strnad , Vladimír Vrkoslav , Anna Mengr , Ondřej Fabián , Jiří Rybáček , Miloš Kubánek , Vojtěch Melenovský , Lenka Maletínská , Josef Cvačka

Deficiency of GPR10 and NPFFR2 receptors leads to sex-specific prediabetic syndrome and late-onset obesity in mice.

Bioscience reports

Avec: Alena Morgan , Nivasini Shekhar , Veronika Strnadová , Zdenko Pirník , Eliška Haasová , Jan Kopecký , Andrea Pačesová , Blanka Železná , Jaroslav Kuneš , Kristina Bardová , Lenka Maletínská

High-fructose drinks affect microRNAs expression differently in lean and obese mice.

The Journal of nutritional biochemistry

Avec: Barbora Hanousková , Barbora Neprašová , Lenka Skálová , Lenka Maletínská , Kateřina Zemanová , Martin Ambrož , Petra Matoušková

Liraglutide and a lipidized analog of prolactin-releasing peptide show neuroprotective effects in a mouse model of β-amyloid pathology.

Neuropharmacology

Avec: Martina Holubová , Lucie Hrubá , Andrea Popelová , Michal Bencze , Veronika Pražienková , Simon Gengler , Helena Kratochvílová , Martin Haluzík , Blanka Železná , Jaroslav Kuneš , Christian Hölscher , Lenka Maletínská

The impact of anorexigenic peptides in experimental models of Alzheimer's disease pathology.

The Journal of endocrinology

Avec: Lenka Maletínská , Andrea Popelová , Blanka Železná , Michal Bencze , Jaroslav Kuneš

The use of 1,5-diaminonaphthalene for matrix-assisted laser desorption/ionization mass spectrometry imaging of brain in neurodegenerative disorders.

Talanta

Avec: Štěpán Strnad , Veronika Pražienková , David Sýkora , Josef Cvačka , Lenka Maletínská , Andrea Popelová , Vladimír Vrkoslav

Palmitoylated Prolactin-releasing Peptide Reduced Aβ Plaques and Microgliosis in the Cerebellum: APP/PS1 Mice Study.

Current Alzheimer research

Avec: Anna Mengr , Lucie Hrubá , Aneta Exnerová , Martina Holubová , Andrea Popelová , Blanka Železná , Jaroslav Kuneš , Lenka Maletínská

Lipidized Prolactin-Releasing Peptide as a New Potential Tool to Treat Obesity and Type 2 Diabetes Mellitus: Preclinical Studies in Rodent Models.

Frontiers in pharmacology

Avec: Lucia Mráziková , Barbora Neprašová , Anna Mengr , Andrea Popelová , Veronika Strnadová , Lucie Holá , Blanka Železná , Jaroslav Kuneš , Lenka Maletínská

MALDI Mass Spectrometry Imaging of Lipids on Free-Floating Brain Sections and Immunohistochemically Colocalized Markers of Neurodegeneration.

Methods in molecular biology (Clifton, N.J.)

Avec: Štěpán Strnad , Veronika Strnadová , David Sýkora , Josef Cvačka , Lenka Maletínská , Vladimír Vrkoslav

High-Fat Diet Induces Resistance to Ghrelin and LEAP2 Peptide Analogs in Mice.

Physiological research

Avec: L Holá , T Tureckiuová , J Kuneš , B Železná , L Maletínská

Age-related metabolic and neurodegenerative changes in SAMP8 mice.

Aging

Avec: Andrea Pačesová , Martina Holubová , Lucie Hrubá , Veronika Strnadová , Barbora Neprašová , Helena Pelantová , Marek Kuzma , Blanka Železná , Jaroslav Kuneš , Lenka Maletínská

GPR160 is not a receptor of anorexigenic cocaine- and amphetamine-regulated transcript peptide.

European journal of pharmacology

Avec: Leandro Ceotto Freitas-Lima , Andrea Pačesová , Jana Staňurová , Pavel Šácha , Aleš Marek , Martin Hubálek , Jaroslav Kuneš , Blanka Železná , Lenka Maletínská

Lipidized analogues of the anorexigenic CART (cocaine- and amphetamine-regulated transcript) neuropeptide show anorexigenic and neuroprotective potential in mouse model of monosodium-glutamate induced obesity.

European journal of pharmacology

Avec: Vilém Charvát , Anna Strnadová , Aneta Myšková , David Sýkora , Miroslava Blechová , Blanka Železná , Jaroslav Kuneš , Lenka Maletínská , Andrea Pačesová

Réseau de co-auteurs

Lenka Maletínská 36 collaborations

Jaroslav Kuneš 28 collaborations

Blanka Železná 26 collaborations

Veronika Strnadová 10 collaborations

Barbora Neprašová 9 collaborations

Martina Holubová 8 collaborations

David Sýkora 8 collaborations

Veronika Pražienková 8 collaborations

Andrea Popelová 8 collaborations

Štěpán Strnad 6 collaborations

Vladimír Vrkoslav 6 collaborations

Alena Karnošová 6 collaborations

Lucie Hrubá 6 collaborations

Andrea Pačesová 6 collaborations

Helena Pelantová 6 collaborations

Marek Kuzma 6 collaborations

Josef Cvačka 5 collaborations

Aneta Myšková 5 collaborations

J Kuneš 5 collaborations

Lucie Holá 4 collaborations

Lucia Mráziková 4 collaborations

Blanka Šedivá 4 collaborations

Anna Mengr 4 collaborations

Lucia Kořínková 3 collaborations

Miroslava Blechová 3 collaborations

B Železná 3 collaborations

Kristina Bardová 3 collaborations

Petra Tomášová 3 collaborations

Michal Bencze 3 collaborations

Martin Haluzík 3 collaborations

Miroslava Kacířová 2 collaborations

Anna Zmeškalová 2 collaborations

L Kořínková 2 collaborations

Zdenko Pirník 2 collaborations

Jan Kopecký 2 collaborations

Silvie Hojná 2 collaborations

Alena Morgan 2 collaborations

Eliška Haasová 2 collaborations

Aneta Exnerová 2 collaborations

Marie-Christine Galas 2 collaborations

Aleš Marek 2 collaborations

Veronika PraŽienková 1 collaboration

Natalie Ben Abu 1 collaboration

Philip E Mason 1 collaboration

Hadar Klein 1 collaboration

Nitzan Dubovski 1 collaboration

Yaron Ben Shoshan-Galeczki 1 collaboration

Einav Malach 1 collaboration

Carmelo Tempra 1 collaboration

Victor Cruces Chamorro 1 collaboration

Maik Behrens 1 collaboration

Masha Y Niv 1 collaboration

Pavel Jungwirth 1 collaboration

Anna Němcová 1 collaboration

H Rauchová 1 collaboration

B Neprašová 1 collaboration

Z Pirník 1 collaboration

J Osacká 1 collaboration

Jiří Funda 1 collaboration

Petra Janovská 1 collaboration

Michal Benzce 1 collaboration

Michaela Kadlecová 1 collaboration

Jaroslav Blahoš 1 collaboration

Magdalena Škrlová 1 collaboration

Petra Vaculová 1 collaboration

Petr Kašpárek 1 collaboration

Claire Schirmer 1 collaboration

V Pražienková 1 collaboration

L Černá 1 collaboration

A Karnošová 1 collaboration

Sara Km Jörgensen 1 collaboration

Simone Mazzaferro 1 collaboration

Oliver Rowley 1 collaboration

Hsiao-Jou Cortina Chen 1 collaboration

Sarah J Robbins 1 collaboration

Sarah Christofides 1 collaboration

Florian T Merkle 1 collaboration

David Petrik 1 collaboration

Martina Čermáková 1 collaboration

Martina Bugáňová 1 collaboration

Michaela Blažková 1 collaboration

Jean-Alain Fehrentz 1 collaboration

Séverine Denoyelle 1 collaboration

Sonia Cantel 1 collaboration

Thomas Comptdaer 1 collaboration

S Hojná 1 collaboration

L Mráziková 1 collaboration

A Montezano 1 collaboration

R M Touyz 1 collaboration

Ondřej Fabián 1 collaboration

Jiří Rybáček 1 collaboration

Miloš Kubánek 1 collaboration

Vojtěch Melenovský 1 collaboration

Nivasini Shekhar 1 collaboration

Barbora Hanousková 1 collaboration

Lenka Skálová 1 collaboration

Kateřina Zemanová 1 collaboration

Martin Ambrož 1 collaboration

Petra Matoušková 1 collaboration

Simon Gengler 1 collaboration

Helena Kratochvílová 1 collaboration

Christian Hölscher 1 collaboration

L Holá 1 collaboration

T Tureckiuová 1 collaboration

Leandro Ceotto Freitas-Lima 1 collaboration

Jana Staňurová 1 collaboration

Pavel Šácha 1 collaboration

Martin Hubálek 1 collaboration

Vilém Charvát 1 collaboration

Anna Strnadová 1 collaboration