Kristiina Rajamäki

Affiliations

Clinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland.

Publications (13)

Gain-of-function CEBPE mutation causes noncanonical autoinflammatory inflammasomopathy.

The Journal of allergy and clinical immunology

Avec: Helka Göös , Christopher L Fogarty , Biswajyoti Sahu , Vincent Plagnol , Kristiina Rajamäki , Katariina Nurmi , Xiaonan Liu , Elisabet Einarsdottir , Annukka Jouppila , Tom Pettersson , Helena Vihinen , Kaarel Krjutskov , Päivi Saavalainen , Asko Järvinen , Mari Muurinen , Dario Greco , Giovanni Scala , James Curtis , Dan Nordström , Robert Flaumenhaft , Outi Vaarala , Panu E Kovanen , Salla Keskitalo , Annamari Ranki , Juha Kere , Markku Lehto , Luigi D Notarangelo , Sergey Nejentsev , Kari K Eklund , Markku Varjosalo , Jussi Taipale , Mikko R J Seppänen

Parity associates with chromosomal damage in uterine leiomyomas.

Nature communications

Avec: Heli Kuisma , Simona Bramante , Kristiina Rajamäki , Lauri J Sipilä , Eevi Kaasinen , Jaana Kaukomaa , Kimmo Palin , Netta Mäkinen , Jari Sjöberg , Nanna Sarvilinna , Jussi Taipale , Liisa Kauppi , Manuela Tumiati , Antti Hassinen , Janne Pitkäniemi , Jyrki Jalkanen , Sanna Heikkinen , Annukka Pasanen , Oskari Heikinheimo , Ralf Bützow , Niko Välimäki , Lauri A Aaltonen

No evidence of EMAST in whole genome sequencing data from 248 colorectal cancers.

Genes, chromosomes & cancer

Avec: Johanna Kondelin , Samantha Martin , Riku Katainen , Laura Renkonen-Sinisalo , Anna Lepistö , Selja Koskensalo , Jan Böhm , Jukka-Pekka Mecklin , Tatiana Cajuso , Ulrika A Hänninen , Niko Välimäki , Janne Ravantti , Kristiina Rajamäki , Kimmo Palin , Lauri A Aaltonen

Vitamin C boosts DNA demethylation in TET2 germline mutation carriers.

Clinical epigenetics

Avec: Aurora Taira , Kimmo Palin , Anna Kuosmanen , Niko Välimäki , Outi Kuittinen , Outi Kuismin , Eevi Kaasinen , Kristiina Rajamäki , Lauri A Aaltonen

Lynch syndrome-associated and sporadic microsatellite unstable colorectal cancers: different patterns of clonal evolution yield highly similar tumours.

Human molecular genetics

Avec: Samantha Martin , Riku Katainen , Aurora Taira , Niko Välimäki , Ari Ristimäki , Toni Seppälä , Laura Renkonen-Sinisalo , Anna Lepistö , Kyösti Tahkola , Anne Mattila , Selja Koskensalo , Jukka-Pekka Mecklin , Kristiina Rajamäki , Kimmo Palin , Lauri A Aaltonen

A Family With A20 Haploinsufficiency Presenting With Novel Clinical Manifestations and Challenges for Treatment.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases

Avec: Timo Hautala , Paula Vähäsalo , Outi Kuismin , Salla Keskitalo , Kristiina Rajamäki , Antti Väänänen , Marja Simojoki , Marjaana Säily , Ilpo Pelkonen , Heikki Tokola , Markus Mäkinen , Riitta Kaarteenaho , Airi Jartti , Nina Hautala , Saara Kantola , Päivi Jackson , Virpi Glumoff , Janna Saarela , Markku Varjosalo , Kari K Eklund , Mikko R J Seppänen

Genetic and Epigenetic Characteristics of Inflammatory Bowel Disease-Associated Colorectal Cancer.

Gastroenterology

Avec: Kristiina Rajamäki , Aurora Taira , Riku Katainen , Niko Välimäki , Anna Kuosmanen , Roosa-Maria Plaketti , Toni T Seppälä , Maarit Ahtiainen , Erkki-Ville Wirta , Emilia Vartiainen , Päivi Sulo , Janne Ravantti , Suvi Lehtipuro , Kirsi J Granberg , Matti Nykter , Tomas Tanskanen , Ari Ristimäki , Selja Koskensalo , Laura Renkonen-Sinisalo , Anna Lepistö , Jan Böhm , Jussi Taipale , Jukka-Pekka Mecklin , Mervi Aavikko , Kimmo Palin , Lauri A Aaltonen

From APC to the genetics of hereditary and familial colon cancer syndromes.

Human molecular genetics

Avec: Alisa P Olkinuora , Päivi T Peltomäki , Lauri A Aaltonen , Kristiina Rajamäki

Novel TMEM173 Mutation and the Role of Disease Modifying Alleles.

Frontiers in immunology

Avec: Salla Keskitalo , Emma Haapaniemi , Elisabet Einarsdottir , Kristiina Rajamäki , Hannele Heikkilä , Mette Ilander , Minna Pöyhönen , Ekaterina Morgunova , Kati Hokynar , Sonja Lagström , Sirpa Kivirikko , Satu Mustjoki , Kari Eklund , Janna Saarela , Juha Kere , Mikko R J Seppänen , Annamari Ranki , Katariina Hannula-Jouppi , Markku Varjosalo

Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans.

Nature communications

Avec: Eevi Kaasinen , Outi Kuismin , Kristiina Rajamäki , Heikki Ristolainen , Mervi Aavikko , Johanna Kondelin , Silva Saarinen , Davide G Berta , Riku Katainen , Elina A M Hirvonen , Auli Karhu , Aurora Taira , Tomas Tanskanen , Amjad Alkodsi , Minna Taipale , Ekaterina Morgunova , Kaarle Franssila , Rainer Lehtonen , Markus Mäkinen , Kristiina Aittomäki , Aarno Palotie , Mitja I Kurki , Olli Pietiläinen , Morgane Hilpert , Elmo Saarentaus , Jaakko Niinimäki , Juhani Junttila , Kari Kaikkonen , Pia Vahteristo , Radek C Skoda , Mikko R J Seppänen , Kari K Eklund , Jussi Taipale , Outi Kilpivaara , Lauri A Aaltonen

Deficient H2A.Z deposition is associated with genesis of uterine leiomyoma.

Nature

Avec: Davide G Berta , Heli Kuisma , Niko Välimäki , Maritta Räisänen , Maija Jäntti , Annukka Pasanen , Auli Karhu , Jaana Kaukomaa , Aurora Taira , Tatiana Cajuso , Sanna Nieminen , Rosa-Maria Penttinen , Saija Ahonen , Rainer Lehtonen , Miika Mehine , Pia Vahteristo , Jyrki Jalkanen , Biswajyoti Sahu , Janne Ravantti , Netta Mäkinen , Kristiina Rajamäki , Kimmo Palin , Jussi Taipale , Oskari Heikinheimo , Ralf Bützow , Eevi Kaasinen , Lauri A Aaltonen

Truncating NFKB1 variants cause combined NLRP3 inflammasome activation and type I interferon signaling and predispose to necrotizing fasciitis.

Cell reports. Medicine

Avec: Katariina Nurmi , Kristiina Silventoinen , Salla Keskitalo , Kristiina Rajamäki , Vesa-Petteri Kouri , Matias Kinnunen , Sami Jalil , Rocio Maldonado , Kirmo Wartiovaara , Elma Inés Nievas , Silvina Paola Denita-Juárez , Christopher J A Duncan , Outi Kuismin , Janna Saarela , Inka Romo , Timi Martelius , Jukka Parantainen , Arzu Beklen , Marcelina Bilicka , Sampsa Matikainen , Dan C Nordström , Meri Kaustio , Ulla Wartiovaara-Kautto , Outi Kilpivaara , Christoph Klein , Fabian Hauck , Tiina Jahkola , Timo Hautala , Markku Varjosalo , Goncalo Barreto , Mikko R J Seppänen , Kari K Eklund

Non-stem cell lineages as an alternative origin of intestinal tumorigenesis in the context of inflammation.

Nature genetics

Avec: Mathijs P Verhagen , Rosalie Joosten , Mark Schmitt , Niko Välimäki , Andrea Sacchetti , Kristiina Rajamäki , Jiahn Choi , Paola Procopio , Sara Silva , Berdine van der Steen , Thierry P P van den Bosch , Danielle Seinstra , Annemarie C de Vries , Michail Doukas , Leonard H Augenlicht , Lauri A Aaltonen , Riccardo Fodde

Réseau de co-auteurs

Lauri A Aaltonen 9 collaborations

Niko Välimäki 7 collaborations

Kimmo Palin 6 collaborations

Jussi Taipale 5 collaborations

Mikko R J Seppänen 5 collaborations

Aurora Taira 5 collaborations

Salla Keskitalo 4 collaborations

Kari K Eklund 4 collaborations

Markku Varjosalo 4 collaborations

Eevi Kaasinen 4 collaborations

Riku Katainen 4 collaborations

Outi Kuismin 4 collaborations

Laura Renkonen-Sinisalo 3 collaborations

Anna Lepistö 3 collaborations

Selja Koskensalo 3 collaborations

Jukka-Pekka Mecklin 3 collaborations

Janne Ravantti 3 collaborations

Janna Saarela 3 collaborations

Biswajyoti Sahu 2 collaborations

Katariina Nurmi 2 collaborations

Elisabet Einarsdottir 2 collaborations

Annamari Ranki 2 collaborations

Juha Kere 2 collaborations

Heli Kuisma 2 collaborations

Jaana Kaukomaa 2 collaborations

Netta Mäkinen 2 collaborations

Jyrki Jalkanen 2 collaborations

Annukka Pasanen 2 collaborations

Oskari Heikinheimo 2 collaborations

Ralf Bützow 2 collaborations

Johanna Kondelin 2 collaborations

Samantha Martin 2 collaborations

Jan Böhm 2 collaborations

Tatiana Cajuso 2 collaborations

Anna Kuosmanen 2 collaborations

Ari Ristimäki 2 collaborations

Timo Hautala 2 collaborations

Markus Mäkinen 2 collaborations

Tomas Tanskanen 2 collaborations

Mervi Aavikko 2 collaborations

Ekaterina Morgunova 2 collaborations

Davide G Berta 2 collaborations

Auli Karhu 2 collaborations

Rainer Lehtonen 2 collaborations

Pia Vahteristo 2 collaborations

Outi Kilpivaara 2 collaborations

Helka Göös 1 collaboration

Christopher L Fogarty 1 collaboration

Vincent Plagnol 1 collaboration

Xiaonan Liu 1 collaboration

Annukka Jouppila 1 collaboration

Tom Pettersson 1 collaboration

Helena Vihinen 1 collaboration

Kaarel Krjutskov 1 collaboration

Päivi Saavalainen 1 collaboration

Asko Järvinen 1 collaboration

Mari Muurinen 1 collaboration

Dario Greco 1 collaboration

Giovanni Scala 1 collaboration

James Curtis 1 collaboration

Dan Nordström 1 collaboration

Robert Flaumenhaft 1 collaboration

Outi Vaarala 1 collaboration

Panu E Kovanen 1 collaboration

Markku Lehto 1 collaboration

Luigi D Notarangelo 1 collaboration

Sergey Nejentsev 1 collaboration

Simona Bramante 1 collaboration

Lauri J Sipilä 1 collaboration

Jari Sjöberg 1 collaboration

Nanna Sarvilinna 1 collaboration

Liisa Kauppi 1 collaboration

Manuela Tumiati 1 collaboration

Antti Hassinen 1 collaboration

Janne Pitkäniemi 1 collaboration

Sanna Heikkinen 1 collaboration

Ulrika A Hänninen 1 collaboration

Outi Kuittinen 1 collaboration

Toni Seppälä 1 collaboration

Kyösti Tahkola 1 collaboration

Anne Mattila 1 collaboration

Paula Vähäsalo 1 collaboration

Antti Väänänen 1 collaboration

Marja Simojoki 1 collaboration

Marjaana Säily 1 collaboration

Ilpo Pelkonen 1 collaboration

Heikki Tokola 1 collaboration

Riitta Kaarteenaho 1 collaboration

Airi Jartti 1 collaboration

Nina Hautala 1 collaboration

Saara Kantola 1 collaboration

Päivi Jackson 1 collaboration

Virpi Glumoff 1 collaboration

Roosa-Maria Plaketti 1 collaboration

Toni T Seppälä 1 collaboration

Maarit Ahtiainen 1 collaboration

Erkki-Ville Wirta 1 collaboration

Emilia Vartiainen 1 collaboration

Päivi Sulo 1 collaboration

Suvi Lehtipuro 1 collaboration

Kirsi J Granberg 1 collaboration

Matti Nykter 1 collaboration

Alisa P Olkinuora 1 collaboration

Päivi T Peltomäki 1 collaboration

Emma Haapaniemi 1 collaboration

Hannele Heikkilä 1 collaboration

Mette Ilander 1 collaboration

Minna Pöyhönen 1 collaboration

Kati Hokynar 1 collaboration

Sonja Lagström 1 collaboration

Sirpa Kivirikko 1 collaboration

Satu Mustjoki 1 collaboration

Kari Eklund 1 collaboration

Katariina Hannula-Jouppi 1 collaboration

Heikki Ristolainen 1 collaboration

Silva Saarinen 1 collaboration

Elina A M Hirvonen 1 collaboration

Amjad Alkodsi 1 collaboration

Minna Taipale 1 collaboration

Kaarle Franssila 1 collaboration

Kristiina Aittomäki 1 collaboration

Aarno Palotie 1 collaboration

Mitja I Kurki 1 collaboration

Olli Pietiläinen 1 collaboration

Morgane Hilpert 1 collaboration

Elmo Saarentaus 1 collaboration

Jaakko Niinimäki 1 collaboration

Juhani Junttila 1 collaboration

Kari Kaikkonen 1 collaboration

Radek C Skoda 1 collaboration

Maritta Räisänen 1 collaboration

Maija Jäntti 1 collaboration

Sanna Nieminen 1 collaboration

Rosa-Maria Penttinen 1 collaboration

Saija Ahonen 1 collaboration

Miika Mehine 1 collaboration

Kristiina Silventoinen 1 collaboration

Vesa-Petteri Kouri 1 collaboration

Matias Kinnunen 1 collaboration

Sami Jalil 1 collaboration

Rocio Maldonado 1 collaboration

Kirmo Wartiovaara 1 collaboration

Elma Inés Nievas 1 collaboration

Silvina Paola Denita-Juárez 1 collaboration

Christopher J A Duncan 1 collaboration

Inka Romo 1 collaboration

Timi Martelius 1 collaboration

Jukka Parantainen 1 collaboration

Arzu Beklen 1 collaboration

Marcelina Bilicka 1 collaboration

Sampsa Matikainen 1 collaboration

Dan C Nordström 1 collaboration

Meri Kaustio 1 collaboration

Ulla Wartiovaara-Kautto 1 collaboration

Christoph Klein 1 collaboration

Fabian Hauck 1 collaboration

Tiina Jahkola 1 collaboration

Goncalo Barreto 1 collaboration

Mathijs P Verhagen 1 collaboration

Rosalie Joosten 1 collaboration

Mark Schmitt 1 collaboration

Andrea Sacchetti 1 collaboration

Jiahn Choi 1 collaboration

Paola Procopio 1 collaboration

Sara Silva 1 collaboration

Berdine van der Steen 1 collaboration

Thierry P P van den Bosch 1 collaboration

Danielle Seinstra 1 collaboration

Annemarie C de Vries 1 collaboration

Michail Doukas 1 collaboration

Leonard H Augenlicht 1 collaboration

Riccardo Fodde 1 collaboration