Klas Hatje

Affiliations

Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Basel, Switzerland.

ORCID: https://orcid.org/0000-0001-5425-8195

Publications (11)

Besca, a single-cell transcriptomics analysis toolkit to accelerate translational research.

NAR genomics and bioinformatics

Avec: Sophia Clara Mädler , Alice Julien-Laferriere , Luis Wyss , Miroslav Phan , Anthony Sonrel , Albert S W Kang , Eric Ulrich , Roland Schmucki , Jitao David Zhang , Martin Ebeling , Laura Badi , Tony Kam-Thong , Petra C Schwalie , Klas Hatje

Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors.

Journal for immunotherapy of cancer

Avec: Marina Natoli , Klas Hatje , Pratiksha Gulati , Fabian Junker , Petra Herzig , Zhiwen Jiang , Iakov I Davydov , Markus Germann , Marta Trüb , Daniel Marbach , Adrian Zwick , Patrick Weber , Stefan Seeber , Mark Wiese , Didier Lardinois , Viola Heinzelmann-Schwarz , Robert Rosenberg , Lothar Tietze , Kirsten D Mertz , Pablo Umaña , Christian Klein , Laura Codarri-Deak , Henry Kao , Alfred Zippelius

Transcriptional profiling upon T cell stimulation reveals down-regulation of inflammatory pathways in T and B cells in SLE versus Sjögren's syndrome.

NPJ systems biology and applications

Avec: Gino Kwon , Annika Wiedemann , Lisa M Steinheuer , Ana-Luisa Stefanski , Franziska Szelinski , Tomas Racek , Andreas Philipp Frei , Klas Hatje , Tony Kam-Thong , David Schubert , Thomas Schindler , Thomas Dörner , Kevin Thurley

Profiling of naïve and primed human pluripotent stem cells reveals state-associated miRNAs.

Scientific reports

Avec: Benjamin T Dodsworth , Klas Hatje , Maria Rostovskaya , Rowan Flynn , Claas A Meyer , Sally A Cowley

Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening.

International journal of molecular sciences

Avec: Simon Gutbier , Florian Wanke , Nadine Dahm , Anna Rümmelin , Silke Zimmermann , Klaus Christensen , Fabian Köchl , Anna Rautanen , Klas Hatje , Barbara Geering , Jitao David Zhang , Markus Britschgi , Sally A Cowley , Christoph Patsch

The Protein-Coding Human Genome: Annotating High-Hanging Fruits.

BioEssays : news and reviews in molecular, cellular and developmental biology

Avec: Klas Hatje , Stefanie Mühlhausen , Dominic Simm , Martin Kollmar

Rates of homology directed repair of CRISPR-Cas9 induced double strand breaks are lower in naïve compared to primed human pluripotent stem cells.

Stem cell research

Avec: Benjamin T Dodsworth , Klas Hatje , Claas Aiko Meyer , Rowan Flynn , Sally A Cowley

Deep Phenotyping of CD11c

Frontiers in immunology

Avec: Hector Rincon-Arevalo , Annika Wiedemann , Ana-Luisa Stefanski , Marie Lettau , Franziska Szelinski , Sebastian Fuchs , Andreas Philipp Frei , Malte Steinberg , Tony Kam-Thong , Klas Hatje , Baerbel Keller , Klaus Warnatz , Andreas Radbruch , Andreia C Lino , Eva Schrezenmeier , Thomas Dörner

Critical assessment of coiled-coil predictions based on protein structure data.

Scientific reports

Avec: Dominic Simm , Klas Hatje , Stephan Waack , Martin Kollmar

Single-cell RNA-sequencing of virus-specific cellular immune responses in chronic hepatitis B patients.

Scientific data

Avec: Klas Hatje , Tony Kam-Thong , Nicolas Giroud , Antonio Saviano , Pauline Simo-Noumbissie , Nadine Kumpesa , Tobias Nilsson , François Habersetzer , Thomas F Baumert , Nadege Pelletier , Marianne Forkel

Actomyosin organelle functions of SPIRE actin nucleators precede animal evolution.

Communications biology

Avec: Martin Kollmar , Tobias Welz , Aishwarya Ravi , Thomas Kaufmann , Noura Alzahofi , Klas Hatje , Asmahan Alghamdi , Jiyu Kim , Deborah A Briggs , Annette Samol-Wolf , Olena Pylypenko , Alistair N Hume , Pawel Burkhardt , Jan Faix , Eugen Kerkhoff

Réseau de co-auteurs

Tony Kam-Thong 4 collaborations

Sally A Cowley 3 collaborations

Martin Kollmar 3 collaborations

Jitao David Zhang 2 collaborations

Annika Wiedemann 2 collaborations

Ana-Luisa Stefanski 2 collaborations

Franziska Szelinski 2 collaborations

Andreas Philipp Frei 2 collaborations

Thomas Dörner 2 collaborations

Benjamin T Dodsworth 2 collaborations

Rowan Flynn 2 collaborations

Dominic Simm 2 collaborations

Sophia Clara Mädler 1 collaboration

Alice Julien-Laferriere 1 collaboration

Luis Wyss 1 collaboration

Miroslav Phan 1 collaboration

Anthony Sonrel 1 collaboration

Albert S W Kang 1 collaboration

Eric Ulrich 1 collaboration

Roland Schmucki 1 collaboration

Martin Ebeling 1 collaboration

Laura Badi 1 collaboration

Petra C Schwalie 1 collaboration

Marina Natoli 1 collaboration

Pratiksha Gulati 1 collaboration

Fabian Junker 1 collaboration

Petra Herzig 1 collaboration

Zhiwen Jiang 1 collaboration

Iakov I Davydov 1 collaboration

Markus Germann 1 collaboration

Marta Trüb 1 collaboration

Daniel Marbach 1 collaboration

Adrian Zwick 1 collaboration

Patrick Weber 1 collaboration

Stefan Seeber 1 collaboration

Mark Wiese 1 collaboration

Didier Lardinois 1 collaboration

Viola Heinzelmann-Schwarz 1 collaboration

Robert Rosenberg 1 collaboration

Lothar Tietze 1 collaboration

Kirsten D Mertz 1 collaboration

Pablo Umaña 1 collaboration

Christian Klein 1 collaboration

Laura Codarri-Deak 1 collaboration

Henry Kao 1 collaboration

Alfred Zippelius 1 collaboration

Gino Kwon 1 collaboration

Lisa M Steinheuer 1 collaboration

Tomas Racek 1 collaboration

David Schubert 1 collaboration

Thomas Schindler 1 collaboration

Kevin Thurley 1 collaboration

Maria Rostovskaya 1 collaboration

Claas A Meyer 1 collaboration

Simon Gutbier 1 collaboration

Florian Wanke 1 collaboration

Nadine Dahm 1 collaboration

Anna Rümmelin 1 collaboration

Silke Zimmermann 1 collaboration

Klaus Christensen 1 collaboration

Fabian Köchl 1 collaboration

Anna Rautanen 1 collaboration

Barbara Geering 1 collaboration

Markus Britschgi 1 collaboration

Christoph Patsch 1 collaboration

Stefanie Mühlhausen 1 collaboration

Claas Aiko Meyer 1 collaboration

Hector Rincon-Arevalo 1 collaboration

Marie Lettau 1 collaboration

Sebastian Fuchs 1 collaboration

Malte Steinberg 1 collaboration

Baerbel Keller 1 collaboration

Klaus Warnatz 1 collaboration

Andreas Radbruch 1 collaboration

Andreia C Lino 1 collaboration

Eva Schrezenmeier 1 collaboration

Stephan Waack 1 collaboration

Nicolas Giroud 1 collaboration

Antonio Saviano 1 collaboration

Pauline Simo-Noumbissie 1 collaboration

Nadine Kumpesa 1 collaboration

Tobias Nilsson 1 collaboration

François Habersetzer 1 collaboration

Thomas F Baumert 1 collaboration

Nadege Pelletier 1 collaboration

Marianne Forkel 1 collaboration

Tobias Welz 1 collaboration

Aishwarya Ravi 1 collaboration

Thomas Kaufmann 1 collaboration

Noura Alzahofi 1 collaboration

Asmahan Alghamdi 1 collaboration

Jiyu Kim 1 collaboration

Deborah A Briggs 1 collaboration

Annette Samol-Wolf 1 collaboration

Olena Pylypenko 1 collaboration

Alistair N Hume 1 collaboration

Pawel Burkhardt 1 collaboration

Jan Faix 1 collaboration

Eugen Kerkhoff 1 collaboration