Markus Britschgi

Affiliations

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Roche Pharma Research and Early Development, Neuroscience Discovery, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.

ORCID: http://orcid.org/0000-0001-6151-4257

Publications (12)

Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age.

Nature metabolism

Avec: Daniel Brigger , Carsten Riether , Robin van Brummelen , Kira I Mosher , Alicia Shiu , Zhaoqing Ding , Noemi Zbären , Pascal Gasser , Pascal Guntern , Hanadie Yousef , Joseph M Castellano , Federico Storni , Neill Graff-Radford , Denis Grandgirard , Magdalena Hinterbrandner , Mark Siegrist , Norman Moullan , Willy Hofstetter , Stephen L Leib , Peter M Villiger , Johan Auwerx , Saul A Villeda , Tony Wyss-Coray , Mario Noti , Alexander Eggel

Multi-platform quantitation of alpha-synuclein human brain proteoforms suggests disease-specific biochemical profiles of synucleinopathies.

Acta neuropathologica communications

Avec: Tim E Moors , Daniel Mona , Stefan Luehe , Gonzalo Duran-Pacheco , Liz Spycher , Olaf Mundigl , Klaus Kaluza , Sylwia Huber , Melanie N Hug , Thomas Kremer , Mirko Ritter , Sebastian Dziadek , Gregor Dernick , Wilma D J van de Berg ,

Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes.

Nature neuroscience

Avec: Sarah H Shahmoradian , Amanda J Lewis , Christel Genoud , Jürgen Hench , Tim E Moors , Paula P Navarro , Daniel Castaño-Díez , Gabriel Schweighauser , Alexandra Graff-Meyer , Kenneth N Goldie , Rosmarie Sütterlin , Evelien Huisman , Angela Ingrassia , Yvonne de Gier , Annemieke J M Rozemuller , Jing Wang , Anne De Paepe , Johannes Erny , Andreas Staempfli , Joerg Hoernschemeyer , Frederik Großerüschkamp , Daniel Niedieker , Samir F El-Mashtoly , Marialuisa Quadri , Wilfred F J Van IJcken , Vincenzo Bonifati , Klaus Gerwert , Bernd Bohrmann , Stephan Frank , Henning Stahlberg , Wilma D J Van de Berg , Matthias E Lauer

Incorporation of stem cell-derived astrocytes into neuronal organoids to allow neuro-glial interactions in toxicological studies.

ALTEX

Avec: Markus Brüll , Anna-Sophie Spreng , Simon Gutbier , Dominik Loser , Alice Krebs , Marvin Reich , Udo Kraushaar , Christoph Patsch , Marcel Leist

The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson's disease brain as revealed by multicolor STED microscopy.

Acta neuropathologica

Avec: Tim E Moors , Christina A Maat , Daniel Niedieker , Daniel Mona , Dennis Petersen , Evelien Timmermans-Huisman , Jeroen Kole , Samir F El-Mashtoly , Liz Spycher , Wagner Zago , Robin Barbour , Olaf Mundigl , Klaus Kaluza , Sylwia Huber , Melanie N Hug , Thomas Kremer , Mirko Ritter , Sebastian Dziadek , Jeroen J G Geurts , Klaus Gerwert , Wilma D J van de Berg

Parkinson mice show functional and molecular changes in the gut long before motoric disease onset.

Molecular neurodegeneration

Avec: Manuela Gries , Anne Christmann , Steven Schulte , Maximilian Weyland , Stephanie Rommel , Monika Martin , Marko Baller , Ralph Röth , Stefanie Schmitteckert , Marcus Unger , Yang Liu , Frederik Sommer , Timo Mühlhaus , Michael Schroda , Jean-Pierre Timmermans , Isabel Pintelon , Gudrun A Rappold , Hilal Lashuel , Michael D Menger , Matthias W Laschke , Beate Niesler , Karl-Herbert Schäfer

Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening.

International journal of molecular sciences

Avec: Simon Gutbier , Florian Wanke , Nadine Dahm , Anna Rümmelin , Silke Zimmermann , Klaus Christensen , Fabian Köchl , Anna Rautanen , Klas Hatje , Barbara Geering , Jitao David Zhang , Sally A Cowley , Christoph Patsch

Alzheimer's Risk Gene TREM2 Determines Functional Properties of New Type of Human iPSC-Derived Microglia.

Frontiers in immunology

Avec: Marvin Reich , Iñaki Paris , Martin Ebeling , Nadine Dahm , Christophe Schweitzer , Dieter Reinhardt , Roland Schmucki , Megana Prasad , Fabian Köchl , Marcel Leist , Sally A Cowley , Jitao David Zhang , Christoph Patsch , Simon Gutbier ,

Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy.

eLife

Avec: Ricardo Guerrero-Ferreira , Nicholas Mi Taylor , Ana-Andreea Arteni , Pratibha Kumari , Daniel Mona , Philippe Ringler , Matthias E Lauer , Ali Makky , Joeri Verasdonck , Roland Riek , Ronald Melki , Beat H Meier , Anja Böckmann , Luc Bousset , Henning Stahlberg

Epigenetic inactivation of the autophagy-lysosomal system in appendix in Parkinson's disease.

Nature communications

Avec: Juozas Gordevicius , Peipei Li , Lee L Marshall , Bryan A Killinger , Sean Lang , Elizabeth Ensink , Nathan C Kuhn , Wei Cui , Nazia Maroof , Roberta Lauria , Christina Rueb , Juliane Siebourg-Polster , Pierre Maliver , Jared Lamp , Irving Vega , Fredric P Manfredsson , Viviane Labrie

Generation of an hiPSC-Derived Co-Culture System to Assess the Effects of Neuroinflammation on Blood-Brain Barrier Integrity.

Cells

Avec: Daniel Bull , Christophe Schweitzer , Colette Bichsel , Simon Gutbier

Trial of Prasinezumab in Early-Stage Parkinson's Disease.

The New England journal of medicine

Avec: Gennaro Pagano , Kirsten I Taylor , Judith Anzures-Cabrera , Maddalena Marchesi , Tanya Simuni , Kenneth Marek , Ronald B Postuma , Nicola Pavese , Fabrizio Stocchi , Jean-Philippe Azulay , Brit Mollenhauer , Lydia López-Manzanares , David S Russell , James T Boyd , Anthony P Nicholas , María R Luquin , Robert A Hauser , Thomas Gasser , Werner Poewe , Benedicte Ricci , Anne Boulay , Annamarie Vogt , Frank G Boess , Juergen Dukart , Giulia D'Urso , Rebecca Finch , Stefano Zanigni , Annabelle Monnet , Nathalie Pross , Andrea Hahn , Hanno Svoboda , Florian Lipsmeier , Ekaterina Volkova-Volkmar , Michael Lindemann , Sebastian Dziadek , Štefan Holiga , Daria Rukina , Thomas Kustermann , Geoffrey A Kerchner , Paulo Fontoura , Daniel Umbricht , Rachelle Doody , Tania Nikolcheva , Azad Bonni , Auteur inconnu , Auteur inconnu

Réseau de co-auteurs

Simon Gutbier 4 collaborations

Tim E Moors 3 collaborations

Daniel Mona 3 collaborations

Sebastian Dziadek 3 collaborations

Christoph Patsch 3 collaborations

Liz Spycher 2 collaborations

Olaf Mundigl 2 collaborations

Klaus Kaluza 2 collaborations

Sylwia Huber 2 collaborations

Melanie N Hug 2 collaborations

Thomas Kremer 2 collaborations

Mirko Ritter 2 collaborations

Wilma D J van de Berg 2 collaborations

Daniel Niedieker 2 collaborations

Samir F El-Mashtoly 2 collaborations

Klaus Gerwert 2 collaborations

Henning Stahlberg 2 collaborations

Matthias E Lauer 2 collaborations

Marvin Reich 2 collaborations

Marcel Leist 2 collaborations

Nadine Dahm 2 collaborations

Fabian Köchl 2 collaborations

Jitao David Zhang 2 collaborations

Sally A Cowley 2 collaborations

Christophe Schweitzer 2 collaborations

None None 2 collaborations

Daniel Brigger 1 collaboration

Carsten Riether 1 collaboration

Robin van Brummelen 1 collaboration

Kira I Mosher 1 collaboration

Alicia Shiu 1 collaboration

Zhaoqing Ding 1 collaboration

Noemi Zbären 1 collaboration

Pascal Gasser 1 collaboration

Pascal Guntern 1 collaboration

Hanadie Yousef 1 collaboration

Joseph M Castellano 1 collaboration

Federico Storni 1 collaboration

Neill Graff-Radford 1 collaboration

Denis Grandgirard 1 collaboration

Magdalena Hinterbrandner 1 collaboration

Mark Siegrist 1 collaboration

Norman Moullan 1 collaboration

Willy Hofstetter 1 collaboration

Stephen L Leib 1 collaboration

Peter M Villiger 1 collaboration

Johan Auwerx 1 collaboration

Saul A Villeda 1 collaboration

Tony Wyss-Coray 1 collaboration

Mario Noti 1 collaboration

Alexander Eggel 1 collaboration

Stefan Luehe 1 collaboration

Gonzalo Duran-Pacheco 1 collaboration

Gregor Dernick 1 collaboration

Sarah H Shahmoradian 1 collaboration

Amanda J Lewis 1 collaboration

Christel Genoud 1 collaboration

Jürgen Hench 1 collaboration

Paula P Navarro 1 collaboration

Daniel Castaño-Díez 1 collaboration

Gabriel Schweighauser 1 collaboration

Alexandra Graff-Meyer 1 collaboration

Kenneth N Goldie 1 collaboration

Rosmarie Sütterlin 1 collaboration

Evelien Huisman 1 collaboration

Angela Ingrassia 1 collaboration

Yvonne de Gier 1 collaboration

Annemieke J M Rozemuller 1 collaboration

Jing Wang 1 collaboration

Anne De Paepe 1 collaboration

Johannes Erny 1 collaboration

Andreas Staempfli 1 collaboration

Joerg Hoernschemeyer 1 collaboration

Frederik Großerüschkamp 1 collaboration

Marialuisa Quadri 1 collaboration

Wilfred F J Van IJcken 1 collaboration

Vincenzo Bonifati 1 collaboration

Bernd Bohrmann 1 collaboration

Stephan Frank 1 collaboration

Wilma D J Van de Berg 1 collaboration

Markus Brüll 1 collaboration

Anna-Sophie Spreng 1 collaboration

Dominik Loser 1 collaboration

Alice Krebs 1 collaboration

Udo Kraushaar 1 collaboration

Christina A Maat 1 collaboration

Dennis Petersen 1 collaboration

Evelien Timmermans-Huisman 1 collaboration

Jeroen Kole 1 collaboration

Wagner Zago 1 collaboration

Robin Barbour 1 collaboration

Jeroen J G Geurts 1 collaboration

Manuela Gries 1 collaboration

Anne Christmann 1 collaboration

Steven Schulte 1 collaboration

Maximilian Weyland 1 collaboration

Stephanie Rommel 1 collaboration

Monika Martin 1 collaboration

Marko Baller 1 collaboration

Ralph Röth 1 collaboration

Stefanie Schmitteckert 1 collaboration

Marcus Unger 1 collaboration

Yang Liu 1 collaboration

Frederik Sommer 1 collaboration

Timo Mühlhaus 1 collaboration

Michael Schroda 1 collaboration

Jean-Pierre Timmermans 1 collaboration

Isabel Pintelon 1 collaboration

Gudrun A Rappold 1 collaboration

Hilal Lashuel 1 collaboration

Michael D Menger 1 collaboration

Matthias W Laschke 1 collaboration

Beate Niesler 1 collaboration

Karl-Herbert Schäfer 1 collaboration

Florian Wanke 1 collaboration

Anna Rümmelin 1 collaboration

Silke Zimmermann 1 collaboration

Klaus Christensen 1 collaboration

Anna Rautanen 1 collaboration

Klas Hatje 1 collaboration

Barbara Geering 1 collaboration

Iñaki Paris 1 collaboration

Martin Ebeling 1 collaboration

Dieter Reinhardt 1 collaboration

Roland Schmucki 1 collaboration

Megana Prasad 1 collaboration

Ricardo Guerrero-Ferreira 1 collaboration

Nicholas Mi Taylor 1 collaboration

Ana-Andreea Arteni 1 collaboration

Pratibha Kumari 1 collaboration

Philippe Ringler 1 collaboration

Ali Makky 1 collaboration

Joeri Verasdonck 1 collaboration

Roland Riek 1 collaboration

Ronald Melki 1 collaboration

Beat H Meier 1 collaboration

Anja Böckmann 1 collaboration

Luc Bousset 1 collaboration

Juozas Gordevicius 1 collaboration

Peipei Li 1 collaboration

Lee L Marshall 1 collaboration

Bryan A Killinger 1 collaboration

Sean Lang 1 collaboration

Elizabeth Ensink 1 collaboration

Nathan C Kuhn 1 collaboration

Wei Cui 1 collaboration

Nazia Maroof 1 collaboration

Roberta Lauria 1 collaboration

Christina Rueb 1 collaboration

Juliane Siebourg-Polster 1 collaboration

Pierre Maliver 1 collaboration

Jared Lamp 1 collaboration

Irving Vega 1 collaboration

Fredric P Manfredsson 1 collaboration

Viviane Labrie 1 collaboration

Daniel Bull 1 collaboration

Colette Bichsel 1 collaboration

Gennaro Pagano 1 collaboration

Kirsten I Taylor 1 collaboration

Judith Anzures-Cabrera 1 collaboration

Maddalena Marchesi 1 collaboration

Tanya Simuni 1 collaboration

Kenneth Marek 1 collaboration

Ronald B Postuma 1 collaboration

Nicola Pavese 1 collaboration

Fabrizio Stocchi 1 collaboration

Jean-Philippe Azulay 1 collaboration

Brit Mollenhauer 1 collaboration

Lydia López-Manzanares 1 collaboration

David S Russell 1 collaboration

James T Boyd 1 collaboration

Anthony P Nicholas 1 collaboration

María R Luquin 1 collaboration

Robert A Hauser 1 collaboration

Thomas Gasser 1 collaboration

Werner Poewe 1 collaboration

Benedicte Ricci 1 collaboration

Anne Boulay 1 collaboration

Annamarie Vogt 1 collaboration

Frank G Boess 1 collaboration

Juergen Dukart 1 collaboration

Giulia D'Urso 1 collaboration

Rebecca Finch 1 collaboration

Stefano Zanigni 1 collaboration

Annabelle Monnet 1 collaboration

Nathalie Pross 1 collaboration

Andrea Hahn 1 collaboration

Hanno Svoboda 1 collaboration

Florian Lipsmeier 1 collaboration

Ekaterina Volkova-Volkmar 1 collaboration

Michael Lindemann 1 collaboration

Štefan Holiga 1 collaboration

Daria Rukina 1 collaboration

Thomas Kustermann 1 collaboration

Geoffrey A Kerchner 1 collaboration

Paulo Fontoura 1 collaboration

Daniel Umbricht 1 collaboration

Rachelle Doody 1 collaboration

Tania Nikolcheva 1 collaboration

Azad Bonni 1 collaboration