Julia Sanz-Aparicio

Affiliations

Macromolecular Crystallography and Structural Biology Department, Institute of Physical-Chemistry 'Rocasolano', CSIC, Madrid, Spain.

Publications (22)

Structural analysis of the reducing-end xylose-releasing exo-oligoxylanase Rex8A from Paenibacillus barcinonensis BP-23 deciphers its molecular specificity.

The FEBS journal

Avec: Elena Jiménez-Ortega , Susana Valenzuela , Mercedes Ramírez-Escudero , Francisco Javier Pastor , Julia Sanz-Aparicio

Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids.

Angewandte Chemie (International ed. in English)

Avec: Patricia Gomez de Santos , Alejandro González-Benjumea , Angela Fernandez-Garcia , Carmen Aranda , Yinqi Wu , Andrada But , Patricia Molina-Espeja , Diana M Maté , David Gonzalez-Perez , Wuyuan Zhang , Jan Kiebist , Katrin Scheibner , Martin Hofrichter , Katarzyna Świderek , Vicent Moliner , Julia Sanz-Aparicio , Frank Hollmann , Ana Gutiérrez , Miguel Alcalde

Structural Insights and Reaction Profile of a New Unspecific Peroxygenase from

ACS chemical biology

Avec: Israel Sánchez-Moreno , Angela Fernandez-Garcia , Ivan Mateljak , Patricia Gomez de Santos , Martin Hofrichter , Harald Kellner , Julia Sanz-Aparicio , Miguel Alcalde

Multiple substrate recognition by yeast diadenosine and diphosphoinositol polyphosphate phosphohydrolase through phosphate clamping.

Science advances

Avec: María Ángeles Márquez-Moñino , Raquel Ortega-García , Megan L Shipton , Elsa Franco-Echevarría , Andrew M Riley , Julia Sanz-Aparicio , Barry V L Potter , Beatriz González

Structural basis of the inhibition of GH1 β-glucosidases by multivalent pyrrolidine iminosugars.

Bioorganic chemistry

Avec: Macarena Martínez-Bailén , Elena Jiménez-Ortega , Ana T Carmona , Inmaculada Robina , Julia Sanz-Aparicio , David Talens-Perales , Julio Polaina , Camilla Matassini , Francesca Cardona , Antonio J Moreno-Vargas

The bone-degrading enzyme machinery: From multi-component understanding to the treatment of residues from the meat industry.

Computational and structural biotechnology journal

Avec: Laura Fernandez-Lopez , Sergio Sanchez-Carrillo , Antonio García-Moyano , Erik Borchert , David Almendral , Sandra Alonso , Isabel Cea-Rama , Noa Miguez , Øivind Larsen , Johannes Werner , Kira S Makarova , Francisco J Plou , Thomas G Dahlgren , Julia Sanz-Aparicio , Ute Hentschel , Gro Elin Kjæreng Bjerga , Manuel Ferrer

Crystal structure of a family VIII β-lactamase fold hydrolase reveals the molecular mechanism for its broad substrate scope.

The FEBS journal

Avec: Isabel Cea-Rama , Cristina Coscolín , Jose L Gonzalez-Alfonso , Jog Raj , Marko Vasiljević , Francisco J Plou , Manuel Ferrer , Julia Sanz-Aparicio

Deciphering the molecular specificity of phenolic compounds as inhibitors or glycosyl acceptors of β-fructofuranosidase from Xanthophyllomyces dendrorhous.

Scientific reports

Avec: Mercedes Ramirez-Escudero , Noa Miguez , Maria Gimeno-Perez , Antonio O Ballesteros , Maria Fernandez-Lobato , Francisco J Plou , Julia Sanz-Aparicio

The cryo-EM Structure of

ACS chemical biology

Avec: Samuel Míguez Amil , Elena Jiménez-Ortega , Mercedes Ramírez-Escudero , David Talens-Perales , Julia Marín-Navarro , Julio Polaina , Julia Sanz-Aparicio , Rafael Fernandez-Leiro

Transforming an esterase into an enantioselective catecholase through bioconjugation of a versatile metal-chelating inhibitor.

Chemical communications (Cambridge, England)

Avec: Laura Fernandez-Lopez , Isabel Cea-Rama , Julia Alvarez-Malmagro , Anna K Ressmann , Jose L Gonzalez-Alfonso , Cristina Coscolín , Patrick Shahgaldian , Francisco J Plou , Jan Modregger , Marcos Pita , Julia Sanz-Aparicio , Manuel Ferrer

Relevance of aromatic and polar amino acids in the specificity of Inulinase ISO3 from Kluyveromyces marxianus: A molecular dynamics approach with an experimental verification.

International journal of biological macromolecules

Avec: Jonathan Trapala , Martín González-Andrade , Clarita Olvera , Maribel Cayetano-Cruz , Julia Sanz-Aparicio , Elena Jimenez-Ortega , Ismael Bustos-Jaimes , Carmina Montiel

Yeast cultures expressing the Ffase from Schwanniomyces occidentalis, a simple system to produce the potential prebiotic sugar 6-kestose.

Applied microbiology and biotechnology

Avec: David Rodrigo-Frutos , David Piedrabuena , Julia Sanz-Aparicio , María Fernández-Lobato

New insights into the molecular mechanism behind mannitol and erythritol fructosylation by β-fructofuranosidase from Schwanniomyces occidentalis.

Scientific reports

Avec: David Rodrigo-Frutos , Elena Jiménez-Ortega , David Piedrabuena , Mercedes Ramírez-Escudero , Noa Míguez , Francisco J Plou , Julia Sanz-Aparicio , María Fernández-Lobato

Structure-Function Insights into the Fungal

International journal of molecular sciences

Avec: Elena Jiménez-Ortega , Peter Elias Kidibule , María Fernández-Lobato , Julia Sanz-Aparicio

Increased Thermostability of an Engineered Flavin-Containing Monooxygenase to Remediate Trimethylamine in Fish Protein Hydrolysates.

Applied and environmental microbiology

Avec: Marianne Goris , Isabel Cea-Rama , Pål Puntervoll , Rasmus Ree , David Almendral , Julia Sanz-Aparicio , Manuel Ferrer , Gro Elin Kjæreng Bjerga

Oligomeric Structure of Yeast and Other Invertases Governs Specificity.

Sub-cellular biochemistry

Avec: Elena Jiménez-Ortega , Julia Sanz-Aparicio

Catalytic Cycle of Glycoside Hydrolase BglX from

ACS chemical biology

Avec: Kiran V Mahasenan , María T Batuecas , Stefania De Benedetti , Choon Kim , Neha Rana , Mijoon Lee , Dusan Hesek , Jed F Fisher , Julia Sanz-Aparicio , Juan A Hermoso , Shahriar Mobashery

Structural inspection and protein motions modelling of a fungal glycoside hydrolase family 18 chitinase by crystallography depicts a dynamic enzymatic mechanism.

Computational and structural biotechnology journal

Avec: Elena Jiménez-Ortega , Peter Elias Kidibule , María Fernández-Lobato , Julia Sanz-Aparicio

Tuning the Properties of Natural Promiscuous Enzymes by Engineering Their Nano-environment.

ACS nano

Avec: Carolina I Giunta , Isabel Cea-Rama , Sandra Alonso , Manon L Briand , Rafael Bargiela , Cristina Coscolín , Philippe F-X Corvini , Manuel Ferrer , Julia Sanz-Aparicio , Patrick Shahgaldian

Structure and evolutionary trace-assisted screening of a residue swapping the substrate ambiguity and chiral specificity in an esterase.

Computational and structural biotechnology journal

Avec: Isabel Cea-Rama , Cristina Coscolín , Panagiotis Katsonis , Rafael Bargiela , Peter N Golyshin , Olivier Lichtarge , Manuel Ferrer , Julia Sanz-Aparicio

Phylogenetic, functional and structural characterization of a GH10 xylanase active at extreme conditions of temperature and alkalinity.

Computational and structural biotechnology journal

Avec: David Talens-Perales , Elena Jiménez-Ortega , Paloma Sánchez-Torres , Julia Sanz-Aparicio , Julio Polaina

The Mobility of the Cap Domain Is Essential for the Substrate Promiscuity of a Family IV Esterase from Sorghum Rhizosphere Microbiome.

Applied and environmental microbiology

Avec: Marco Distaso , Isabel Cea-Rama , Cristina Coscolín , Tatyana N Chernikova , Hai Tran , Manuel Ferrer , Julia Sanz-Aparicio , Peter N Golyshin

Réseau de co-auteurs

Elena Jiménez-Ortega 8 collaborations

Isabel Cea-Rama 7 collaborations

Manuel Ferrer 7 collaborations

Francisco J Plou 5 collaborations

Cristina Coscolín 5 collaborations

María Fernández-Lobato 4 collaborations

Mercedes Ramírez-Escudero 3 collaborations

David Talens-Perales 3 collaborations

Julio Polaina 3 collaborations

Patricia Gomez de Santos 2 collaborations

Angela Fernandez-Garcia 2 collaborations

Martin Hofrichter 2 collaborations

Miguel Alcalde 2 collaborations

Laura Fernandez-Lopez 2 collaborations

David Almendral 2 collaborations

Sandra Alonso 2 collaborations

Noa Miguez 2 collaborations

Gro Elin Kjæreng Bjerga 2 collaborations

Jose L Gonzalez-Alfonso 2 collaborations

Patrick Shahgaldian 2 collaborations

David Rodrigo-Frutos 2 collaborations

David Piedrabuena 2 collaborations

Peter Elias Kidibule 2 collaborations

Rafael Bargiela 2 collaborations

Peter N Golyshin 2 collaborations

Susana Valenzuela 1 collaboration

Francisco Javier Pastor 1 collaboration

Alejandro González-Benjumea 1 collaboration

Carmen Aranda 1 collaboration

Yinqi Wu 1 collaboration

Andrada But 1 collaboration

Patricia Molina-Espeja 1 collaboration

Diana M Maté 1 collaboration

David Gonzalez-Perez 1 collaboration

Wuyuan Zhang 1 collaboration

Jan Kiebist 1 collaboration

Katrin Scheibner 1 collaboration

Katarzyna Świderek 1 collaboration

Vicent Moliner 1 collaboration

Frank Hollmann 1 collaboration

Ana Gutiérrez 1 collaboration

Israel Sánchez-Moreno 1 collaboration

Ivan Mateljak 1 collaboration

Harald Kellner 1 collaboration

María Ángeles Márquez-Moñino 1 collaboration

Raquel Ortega-García 1 collaboration

Megan L Shipton 1 collaboration

Elsa Franco-Echevarría 1 collaboration

Andrew M Riley 1 collaboration

Barry V L Potter 1 collaboration

Beatriz González 1 collaboration

Macarena Martínez-Bailén 1 collaboration

Ana T Carmona 1 collaboration

Inmaculada Robina 1 collaboration

Camilla Matassini 1 collaboration

Francesca Cardona 1 collaboration

Antonio J Moreno-Vargas 1 collaboration

Sergio Sanchez-Carrillo 1 collaboration

Antonio García-Moyano 1 collaboration

Erik Borchert 1 collaboration

Øivind Larsen 1 collaboration

Johannes Werner 1 collaboration

Kira S Makarova 1 collaboration

Thomas G Dahlgren 1 collaboration

Ute Hentschel 1 collaboration

Jog Raj 1 collaboration

Marko Vasiljević 1 collaboration

Mercedes Ramirez-Escudero 1 collaboration

Maria Gimeno-Perez 1 collaboration

Antonio O Ballesteros 1 collaboration

Maria Fernandez-Lobato 1 collaboration

Samuel Míguez Amil 1 collaboration

Julia Marín-Navarro 1 collaboration

Rafael Fernandez-Leiro 1 collaboration

Julia Alvarez-Malmagro 1 collaboration

Anna K Ressmann 1 collaboration

Jan Modregger 1 collaboration

Marcos Pita 1 collaboration

Jonathan Trapala 1 collaboration

Martín González-Andrade 1 collaboration

Clarita Olvera 1 collaboration

Maribel Cayetano-Cruz 1 collaboration

Elena Jimenez-Ortega 1 collaboration

Ismael Bustos-Jaimes 1 collaboration

Carmina Montiel 1 collaboration

Noa Míguez 1 collaboration

Marianne Goris 1 collaboration

Pål Puntervoll 1 collaboration

Rasmus Ree 1 collaboration

Kiran V Mahasenan 1 collaboration

María T Batuecas 1 collaboration

Stefania De Benedetti 1 collaboration

Choon Kim 1 collaboration

Neha Rana 1 collaboration

Mijoon Lee 1 collaboration

Dusan Hesek 1 collaboration

Jed F Fisher 1 collaboration

Juan A Hermoso 1 collaboration

Shahriar Mobashery 1 collaboration

Carolina I Giunta 1 collaboration

Manon L Briand 1 collaboration

Philippe F-X Corvini 1 collaboration

Panagiotis Katsonis 1 collaboration

Olivier Lichtarge 1 collaboration

Paloma Sánchez-Torres 1 collaboration

Marco Distaso 1 collaboration

Tatyana N Chernikova 1 collaboration

Hai Tran 1 collaboration