Jessica Spires

Affiliations

Simulations Plus, Inc., 42505 10th Street West, Lancaster, California, 93534, USA.

Publications (7)

Ocular Physiologically Based Pharmacokinetic Modeling for Ointment Formulations.

Pharmaceutical research

Avec: Maxime Le Merdy , Jessica Spires , Viera Lukacova , Ming-Liang Tan , Andrew Babiskin , Xiaoming Xu , Liang Zhao , Michael B Bolger

Mechanistic modeling of drug products applied to the skin: A workshop summary report.

CPT: pharmacometrics & systems pharmacology

Avec: Eleftheria Tsakalozou , Khondoker Alam , Priyanka Ghosh , Jessica Spires , Sebastian Polak , Lanyan Fang , Srinivasa Sammeta , Ping Zhao , Sumit Arora , Sam G Raney

Application of Mechanistic Ocular Absorption Modeling and Simulation to Understand the Impact of Formulation Properties on Ophthalmic Bioavailability in Rabbits: a Case Study Using Dexamethasone Suspension.

The AAPS journal

Avec: Maxime Le Merdy , Jianghong Fan , Michael B Bolger , Viera Lukacova , Jessica Spires , Eleftheria Tsakalozou , Vikram Patel , Lin Xu , Sharron Stewart , Ashok Chockalingam , Suresh Narayanasamy , Rodney Rouse , Murali Matta , Andrew Babiskin , Darby Kozak , Stephanie Choi , Lei Zhang , Robert Lionberger , Liang Zhao

Predicting Human Dermal Drug Concentrations Using PBPK Modeling and Simulation: Clobetasol Propionate Case Study.

AAPS PharmSciTech

Avec: William W van Osdol , Jasmina Novakovic , Maxime Le Merdy , Eleftheria Tsakalozou , Priyanka Ghosh , Jessica Spires , Viera Lukacova

Physiologically Based Pharmacokinetic (PBPK) Model Predictions of Disease Mediated Changes in Drug Disposition in Patients with Nonalcoholic Fatty Liver Disease (NAFLD).

Pharmaceutical research

Avec: Jeffry Adiwidjaja , Jessica Spires , Kim L R Brouwer

Clinical Ocular Exposure Extrapolation for a Complex Ophthalmic Suspension Using Physiologically Based Pharmacokinetic Modeling and Simulation.

Pharmaceutics

Avec: Maxime Le Merdy , Jessica Spires , Ming-Liang Tan , Liang Zhao , Viera Lukacova

Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH).

Clinical pharmacology and therapeutics

Avec: William A Murphy , Jeffry Adiwidjaja , Noora Sjöstedt , Kyunghee Yang , James J Beaudoin , Jessica Spires , Scott Q Siler , Sibylle Neuhoff , Kim L R Brouwer

Réseau de co-auteurs

Maxime Le Merdy 4 collaborations

Viera Lukacova 4 collaborations

Liang Zhao 3 collaborations

Eleftheria Tsakalozou 3 collaborations

Ming-Liang Tan 2 collaborations

Andrew Babiskin 2 collaborations

Michael B Bolger 2 collaborations

Priyanka Ghosh 2 collaborations

Jeffry Adiwidjaja 2 collaborations

Kim L R Brouwer 2 collaborations

Xiaoming Xu 1 collaboration

Khondoker Alam 1 collaboration

Sebastian Polak 1 collaboration

Lanyan Fang 1 collaboration

Srinivasa Sammeta 1 collaboration

Ping Zhao 1 collaboration

Sumit Arora 1 collaboration

Sam G Raney 1 collaboration

Jianghong Fan 1 collaboration

Vikram Patel 1 collaboration

Lin Xu 1 collaboration

Sharron Stewart 1 collaboration

Ashok Chockalingam 1 collaboration

Suresh Narayanasamy 1 collaboration

Rodney Rouse 1 collaboration

Murali Matta 1 collaboration

Darby Kozak 1 collaboration

Stephanie Choi 1 collaboration

Lei Zhang 1 collaboration

Robert Lionberger 1 collaboration

William W van Osdol 1 collaboration

Jasmina Novakovic 1 collaboration

William A Murphy 1 collaboration

Noora Sjöstedt 1 collaboration

Kyunghee Yang 1 collaboration

James J Beaudoin 1 collaboration

Scott Q Siler 1 collaboration

Sibylle Neuhoff 1 collaboration