Jürgen Zanghellini

Affiliations

Acib - Austrian Centre of Industrial Biotechnology, 1190, Vienna, Austria; Department of Analytical Chemistry, University of Vienna, 1010, Vienna, Austria. Electronic address: juergen.zanghellini@univie.ac.at.

Publications (30)

What CHO is made of: Variations in the biomass composition of Chinese hamster ovary cell lines.

Metabolic engineering

Avec: Diana Széliová , David E Ruckerbauer , Sarah N Galleguillos , Lars B Petersen , Klaus Natter , Michael Hanscho , Christina Troyer , Tim Causon , Harald Schoeny , Hanne B Christensen , Dong-Yup Lee , Nathan E Lewis , Gunda Koellensperger , Stephan Hann , Lars K Nielsen , Nicole Borth , Jürgen Zanghellini

Environmental flexibility does not explain metabolic robustness.

NPJ systems biology and applications

Avec: Julian Libiseller-Egger , Benjamin Luke Coltman , Matthias P Gerstl , Jürgen Zanghellini

Tailored Mass Spectral Data Exploration Using the SpecXplore Interactive Dashboard.

Analytical chemistry

Avec: Kevin Mildau , Henry Ehlers , Ian Oesterle , Manuel Pristner , Benedikt Warth , Maria Doppler , Christoph Bueschl , Jürgen Zanghellini , Justin J J van der Hooft

Probabilistic quotient's work and pharmacokinetics' contribution: countering size effect in metabolic time series measurements.

BMC bioinformatics

Avec: Mathias Gotsmy , Julia Brunmair , Christoph Büschl , Christopher Gerner , Jürgen Zanghellini

Dissecting peak broadening in chromatography columns under non-binding conditions.

Journal of chromatography. A

Avec: Dmytro Iurashev , Susanne Schweiger , Alois Jungbauer , Jürgen Zanghellini

Flux tope analysis: studying the coordination of reaction directions in metabolic networks.

Bioinformatics (Oxford, England)

Avec: Matthias P Gerstl , Stefan Müller , Georg Regensburger , Jürgen Zanghellini

Homologue series detection and management in LC-MS data with homologueDiscoverer.

Bioinformatics (Oxford, England)

Avec: Kevin Mildau , Justin J J van der Hooft , Mira Flasch , Benedikt Warth , Yasin El Abiead , Gunda Koellensperger , Jürgen Zanghellini , Christoph Büschl

The sources and transmission routes of microbial populations throughout a meat processing facility.

NPJ biofilms and microbiomes

Avec: Benjamin Zwirzitz , Stefanie U Wetzels , Emmanuel D Dixon , Beatrix Stessl , Andreas Zaiser , Isabel Rabanser , Sarah Thalguter , Beate Pinior , Franz-Ferdinand Roch , Cameron Strachan , Jürgen Zanghellini , Monika Dzieciol , Martin Wagner , Evelyne Selberherr

The secretome of Pichia pastoris in fed-batch cultivations is largely independent of the carbon source but changes quantitatively over cultivation time.

Microbial biotechnology

Avec: Jonas Burgard , Clemens Grünwald-Gruber , Friedrich Altmann , Jürgen Zanghellini , Minoska Valli , Diethard Mattanovich , Brigitte Gasser

Error propagation in constraint-based modeling of Chinese hamster ovary cells.

Biotechnology journal

Avec: Diana Széliová , Dmytro Iurashev , David E Ruckerbauer , Gunda Koellensperger , Nicole Borth , Michael Melcher , Jürgen Zanghellini

Towards rational glyco-engineering in CHO: from data to predictive models.

Current opinion in biotechnology

Avec: Jerneja Štor , David E Ruckerbauer , Diana Széliová , Jürgen Zanghellini , Nicole Borth

Costs of ribosomal RNA stabilization affect ribosome composition at maximum growth rate.

Communications biology

Avec: Diana Széliová , Stefan Müller , Jürgen Zanghellini

PyCoMo: a python package for community metabolic model creation and analysis.

Bioinformatics (Oxford, England)

Avec: Michael Predl , Marianne Mießkes , Thomas Rattei , Jürgen Zanghellini

Impact of nutrient excess on physiology and metabolism of

Frontiers in microbiology

Avec: Viktor Laurin Sedlmayr , Diana Széliová , Veerke De Kock , Yannick Gansemans , Filip Van Nieuwerburgh , Eveline Peeters , Julian Quehenberger , Jürgen Zanghellini , Oliver Spadiut

Robust Analytical Methods for the Accurate Quantification of the Total Biomass Composition of Mammalian Cells.

Methods in molecular biology (Clifton, N.J.)

Avec: Diana Széliová , Harald Schoeny , Špela Knez , Christina Troyer , Cristina Coman , Evelyn Rampler , Gunda Koellensperger , Robert Ahrends , Stephen Hann , Nicole Borth , Jürgen Zanghellini , David E Ruckerbauer

Finger sweat analysis enables short interval metabolic biomonitoring in humans.

Nature communications

Avec: Julia Brunmair , Mathias Gotsmy , Laura Niederstaetter , Benjamin Neuditschko , Andrea Bileck , Astrid Slany , Max Lennart Feuerstein , Clemens Langbauer , Lukas Janker , Jürgen Zanghellini , Samuel M Meier-Menches , Christopher Gerner

Inclusion of maintenance energy improves the intracellular flux predictions of CHO.

PLoS computational biology

Avec: Diana Széliová , Jerneja Štor , Isabella Thiel , Marcus Weinguny , Michael Hanscho , Gabriele Lhota , Nicole Borth , Jürgen Zanghellini , David E Ruckerbauer , Isabel Rocha

Elementary vectors and autocatalytic sets for resource allocation in next-generation models of cellular growth.

PLoS computational biology

Avec: Stefan Müller , Diana Széliová , Jürgen Zanghellini

PeakBot: machine-learning-based chromatographic peak picking.

Bioinformatics (Oxford, England)

Avec: Christoph Bueschl , Maria Doppler , Elisabeth Varga , Bernhard Seidl , Mira Flasch , Benedikt Warth , Juergen Zanghellini

Heterogeneous multimeric metabolite ion species observed in LC-MS based metabolomics data sets.

Analytica chimica acta

Avec: Yasin El Abiead , Christoph Bueschl , Lisa Panzenboeck , Mingxun Wang , Maria Doppler , Bernhard Seidl , Jürgen Zanghellini , Pieter C Dorrestein , Gunda Koellensperger

MeXpose-A Modular Imaging Pipeline for the Quantitative Assessment of Cellular Metal Bioaccumulation.

JACS Au

Avec: Gabriel Braun , Martin Schaier , Paulina Werner , Sarah Theiner , Jürgen Zanghellini , Lukas Wisgrill , Nanna Fyhrquist , Gunda Koellensperger

Combined LC-MS/MS feature grouping, statistical prioritization, and interactive networking in msFeaST.

Bioinformatics (Oxford, England)

Avec: Kevin Mildau , Christoph Büschl , Jürgen Zanghellini , Justin J J van der Hooft

Genetic and Epigenetic Variation across Genes Involved in Energy Metabolism and Mitochondria of Chinese Hamster Ovary Cell Lines.

Biotechnology journal

Avec: Heena Dhiman , Matthias P Gerstl , David Ruckerbauer , Michael Hanscho , Heinz Himmelbauer , Colin Clarke , Niall Barron , Jürgen Zanghellini , Nicole Borth

Thermodynamic Genome-Scale Metabolic Modeling of Metallodrug Resistance in Colorectal Cancer.

Cancers

Avec: Helena A Herrmann , Mate Rusz , Dina Baier , Michael A Jakupec , Bernhard K Keppler , Walter Berger , Gunda Koellensperger , Jürgen Zanghellini

EFMlrs: a Python package for elementary flux mode enumeration via lexicographic reverse search.

BMC bioinformatics

Avec: Bianca A Buchner , Jürgen Zanghellini

Sulfate limitation increases specific plasmid DNA yield and productivity in E. coli fed-batch processes.

Microbial cell factories

Avec: Mathias Gotsmy , Florian Strobl , Florian Weiß , Petra Gruber , Barbara Kraus , Juergen Mairhofer , Jürgen Zanghellini

Optimizing VLP production in gene therapy: Opportunities and challenges for in silico modeling.

Biotechnology journal

Avec: Leopold Zehetner , Diana Széliová , Barbara Kraus , Michael Graninger , Jürgen Zanghellini , Juan A Hernandez Bort

Characterising the metabolic rewiring of extremely slow growing Komagataella phaffii.

Microbial biotechnology

Avec: Benjamin Luke Coltman , Corinna Rebnegger , Brigitte Gasser , Jürgen Zanghellini

ecmtool: fast and memory-efficient enumeration of elementary conversion modes.

Bioinformatics (Oxford, England)

Avec: Bianca Buchner , Tom J Clement , Daan H de Groot , Jürgen Zanghellini

Logistic PCA explains differences between genome-scale metabolic models in terms of metabolic pathways.

PLoS computational biology

Avec: Leopold Zehetner , Diana Széliová , Barbara Kraus , Juan A Hernandez Bort , Jürgen Zanghellini

Réseau de co-auteurs

Diana Széliová 10 collaborations

Gunda Koellensperger 7 collaborations

Nicole Borth 6 collaborations

David E Ruckerbauer 5 collaborations

Michael Hanscho 3 collaborations

Matthias P Gerstl 3 collaborations

Kevin Mildau 3 collaborations

Benedikt Warth 3 collaborations

Maria Doppler 3 collaborations

Christoph Bueschl 3 collaborations

Justin J J van der Hooft 3 collaborations

Mathias Gotsmy 3 collaborations

Christoph Büschl 3 collaborations

Stefan Müller 3 collaborations

Barbara Kraus 3 collaborations

Christina Troyer 2 collaborations

Harald Schoeny 2 collaborations

Benjamin Luke Coltman 2 collaborations

Julia Brunmair 2 collaborations

Christopher Gerner 2 collaborations

Dmytro Iurashev 2 collaborations

Mira Flasch 2 collaborations

Yasin El Abiead 2 collaborations

Brigitte Gasser 2 collaborations

Jerneja Štor 2 collaborations

Bernhard Seidl 2 collaborations

Leopold Zehetner 2 collaborations

Juan A Hernandez Bort 2 collaborations

Sarah N Galleguillos 1 collaboration

Lars B Petersen 1 collaboration

Klaus Natter 1 collaboration

Tim Causon 1 collaboration

Hanne B Christensen 1 collaboration

Dong-Yup Lee 1 collaboration

Nathan E Lewis 1 collaboration

Stephan Hann 1 collaboration

Lars K Nielsen 1 collaboration

Julian Libiseller-Egger 1 collaboration

Henry Ehlers 1 collaboration

Ian Oesterle 1 collaboration

Manuel Pristner 1 collaboration

Susanne Schweiger 1 collaboration

Alois Jungbauer 1 collaboration

Georg Regensburger 1 collaboration

Benjamin Zwirzitz 1 collaboration

Stefanie U Wetzels 1 collaboration

Emmanuel D Dixon 1 collaboration

Beatrix Stessl 1 collaboration

Andreas Zaiser 1 collaboration

Isabel Rabanser 1 collaboration

Sarah Thalguter 1 collaboration

Beate Pinior 1 collaboration

Franz-Ferdinand Roch 1 collaboration

Cameron Strachan 1 collaboration

Monika Dzieciol 1 collaboration

Martin Wagner 1 collaboration

Evelyne Selberherr 1 collaboration

Jonas Burgard 1 collaboration

Clemens Grünwald-Gruber 1 collaboration

Friedrich Altmann 1 collaboration

Minoska Valli 1 collaboration

Diethard Mattanovich 1 collaboration

Michael Melcher 1 collaboration

Michael Predl 1 collaboration

Marianne Mießkes 1 collaboration

Thomas Rattei 1 collaboration

Viktor Laurin Sedlmayr 1 collaboration

Veerke De Kock 1 collaboration

Yannick Gansemans 1 collaboration

Filip Van Nieuwerburgh 1 collaboration

Eveline Peeters 1 collaboration

Julian Quehenberger 1 collaboration

Oliver Spadiut 1 collaboration

Špela Knez 1 collaboration

Cristina Coman 1 collaboration

Evelyn Rampler 1 collaboration

Robert Ahrends 1 collaboration

Stephen Hann 1 collaboration

Laura Niederstaetter 1 collaboration

Benjamin Neuditschko 1 collaboration

Andrea Bileck 1 collaboration

Astrid Slany 1 collaboration

Max Lennart Feuerstein 1 collaboration

Clemens Langbauer 1 collaboration

Lukas Janker 1 collaboration

Samuel M Meier-Menches 1 collaboration

Isabella Thiel 1 collaboration

Marcus Weinguny 1 collaboration

Gabriele Lhota 1 collaboration

Isabel Rocha 1 collaboration

Elisabeth Varga 1 collaboration

Juergen Zanghellini 1 collaboration

Lisa Panzenboeck 1 collaboration

Mingxun Wang 1 collaboration

Pieter C Dorrestein 1 collaboration

Gabriel Braun 1 collaboration

Martin Schaier 1 collaboration

Paulina Werner 1 collaboration

Sarah Theiner 1 collaboration

Lukas Wisgrill 1 collaboration

Nanna Fyhrquist 1 collaboration

Heena Dhiman 1 collaboration

David Ruckerbauer 1 collaboration

Heinz Himmelbauer 1 collaboration

Colin Clarke 1 collaboration

Niall Barron 1 collaboration

Helena A Herrmann 1 collaboration

Mate Rusz 1 collaboration

Dina Baier 1 collaboration

Michael A Jakupec 1 collaboration

Bernhard K Keppler 1 collaboration

Walter Berger 1 collaboration

Bianca A Buchner 1 collaboration

Florian Strobl 1 collaboration

Florian Weiß 1 collaboration

Petra Gruber 1 collaboration

Juergen Mairhofer 1 collaboration

Michael Graninger 1 collaboration

Corinna Rebnegger 1 collaboration

Bianca Buchner 1 collaboration

Tom J Clement 1 collaboration

Daan H de Groot 1 collaboration