Hassan Choucair

Affiliations

Pharmacogenomics and Drug Development Group, Sydney Pharmacy School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW 2006, Australia.

ORCID: 0000-0002-0264-4438

Publications (6)

The Novel Anticancer Aryl-Ureido Fatty Acid CTU Increases Reactive Oxygen Species Production That Impairs Mitochondrial Fusion Mechanisms and Promotes MDA-MB-231 Cell Death.

International journal of molecular sciences

Avec: Stanton Tam , Balasubrahmanyam Umashankar , Md Khalilur Rahman , Hassan Choucair , Tristan Rawling , Michael Murray

The inositol-requiring enzyme 1 (IRE1) endoplasmic reticulum stress pathway promotes MDA-MB-231 cell survival and renewal in response to the aryl-ureido fatty acid CTU.

The international journal of biochemistry & cell biology

Avec: Md Khalilur Rahman , Balasubrahmanyam Umashankar , Hassan Choucair , Kirsi Bourget , Tristan Rawling , Michael Murray

Inclusion of the in-chain sulfur in 3-thiaCTU increases the efficiency of mitochondrial targeting and cell killing by anticancer aryl-urea fatty acids.

European journal of pharmacology

Avec: Md Khalilur Rahman , Balasubrahmanyam Umashankar , Hassan Choucair , Curtis Pazderka , Kirsi Bourget , Yongjuan Chen , Colin R Dunstan , Tristan Rawling , Michael Murray

Aryl-urea fatty acids that activate the p38 MAP kinase and down-regulate multiple cyclins decrease the viability of MDA-MB-231 breast cancer cells.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Avec: Yassir Al-Zubaidi , Curtis Pazderka , Nooshin Koolaji , Md Khalilur Rahman , Hassan Choucair , Bala Umashankar , Kirsi Bourget , Yongjuan Chen , Tristan Rawling , Michael Murray

PTU, a novel ureido-fatty acid, inhibits MDA-MB-231 cell invasion and dissemination by modulating Wnt5a secretion and cytoskeletal signaling.

Biochemical pharmacology

Avec: Yassir Al-Zubaidi , Yongjuan Chen , Md Khalilur Rahman , Bala Umashankar , Hassan Choucair , Kirsi Bourget , Long Chung , Yanfei Qi , Paul K Witting , Robin L Anderson , Geraldine M O'Neill , Colin R Dunstan , Tristan Rawling , Michael Murray

The aryl-ureido fatty acid CTU activates endoplasmic reticulum stress and PERK/NOXA-mediated apoptosis in tumor cells by a dual mitochondrial-targeting mechanism.

Cancer letters

Avec: Hassan Choucair , Md Khalilur Rahman , Balasubrahmanyam Umashankar , Yassir Al-Zubaidi , Kirsi Bourget , Yongjuan Chen , Colin Dunstan , Tristan Rawling , Michael Murray

Réseau de co-auteurs

Md Khalilur Rahman 6 collaborations

Tristan Rawling 6 collaborations

Michael Murray 6 collaborations

Kirsi Bourget 5 collaborations

Balasubrahmanyam Umashankar 4 collaborations

Yongjuan Chen 4 collaborations

Yassir Al-Zubaidi 3 collaborations

Curtis Pazderka 2 collaborations

Colin R Dunstan 2 collaborations

Bala Umashankar 2 collaborations

Stanton Tam 1 collaboration

Nooshin Koolaji 1 collaboration

Long Chung 1 collaboration

Yanfei Qi 1 collaboration

Paul K Witting 1 collaboration

Robin L Anderson 1 collaboration

Geraldine M O'Neill 1 collaboration

Colin Dunstan 1 collaboration