Gilles Gouspillou

Affiliations

Research Institute of the McGill University Health Centre, Department of Critical Care, Montréal, QC H4A 3J1, Canada.
Meakins-Christie Laboratories, Department of Medicine, McGill University, Montréal, QC H4A 3J1, Canada.
Département des Sciences de l'activité Physique, Faculté des Sciences, UQAM, Montréal, QC H2X 1Y4, Canada.
Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, QC H3W 1W5, Canada.

ORCID: 0000-0002-8543-3619

Publications (30)

Mitochondrial Dynamics and Mitophagy in Skeletal Muscle Health and Aging.

International journal of molecular sciences

Avec: Jean-Philippe Leduc-Gaudet , Sabah N A Hussain , Esther Barreiro , Gilles Gouspillou

Acute ingestion of a ketone monoester, whey protein, or their co-ingestion in the overnight postabsorptive state elicit a similar stimulation of myofibrillar protein synthesis rates in young males: a double-blind randomized trial.

The American journal of clinical nutrition

Avec: Sarkis J Hannaian , Jamie Lov , Stephanie E Hawley , Manon Dargegen , Divine Malenda , Ari Gritsas , Gilles Gouspillou , José A Morais , Tyler A Churchward-Venne

Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions.

The journals of gerontology. Series A, Biological sciences and medical sciences

Avec: Guy Hajj-Boutros , Andréa Faust , John Muscedere , Perry Kim , Naji Abumrad , Stéphanie Chevalier , Mylene Aubertin-Leheudre , Howard Bergman , Dawn Bowdish , Jessica Burford , Stacy Carrington-Lawrence , Hélène Côté , David E Dawe , Philipe de Souto Barreto , Colin Farrelly , Robert Fowler , Gilles Gouspillou , Lea Harrington , Sofie Lautrup , Susan Howlett , Mahdi Imani , James Kirkland , George Kuchel , Frédérick A Mallette , José A Morais , John C Newman , Daryl Pullman , Felipe Sierra , Jeremy Van Raamsdonk , Jennifer Watt , R Jane Rylett , Gustavo Duque

Parkin Overexpression Attenuates Sepsis-Induced Muscle Wasting.

Cells

Avec: Jean-Philippe Leduc-Gaudet , Dominique Mayaki , Olivier Reynaud , Felipe E Broering , Tomer J Chaffer , Sabah N A Hussain , Gilles Gouspillou

Regulation of muscle and mitochondrial health by the mitochondrial fission protein Drp1 in aged mice.

The Journal of physiology

Avec: Maude Dulac , Jean-Philippe Leduc-Gaudet , Marina Cefis , Marie-Belle Ayoub , Olivier Reynaud , Anwar Shams , Alaa Moamer , Marcos Francisco Nery Ferreira , Sabah Na Hussain , Gilles Gouspillou

Parkin: a potential target to promote healthy ageing.

The Journal of physiology

Avec: Jean-Philippe Leduc-Gaudet , Sabah Na Hussain , Gilles Gouspillou

MYTHO is a novel regulator of skeletal muscle autophagy and integrity.

Nature communications

Avec: Jean-Philippe Leduc-Gaudet , Anais Franco-Romero , Marina Cefis , Alaa Moamer , Felipe E Broering , Giulia Milan , Roberta Sartori , Tomer Jordi Chaffer , Maude Dulac , Vincent Marcangeli , Dominique Mayaki , Laurent Huck , Anwar Shams , José A Morais , Elise Duchesne , Hanns Lochmuller , Marco Sandri , Sabah N A Hussain , Gilles Gouspillou

Lack of compensatory mitophagy in skeletal muscles during sepsis.

The Journal of physiology

Avec: Sami Sedraoui , Jean-Philippe Leduc-Gaudet , Dominique Mayaki , Alaa Moamer , Laurent Huck , Gilles Gouspillou , Basil J Petrof , Sabah Hussain

Effects of slow-

The British journal of nutrition

Avec: M C Dulac , C H Pion , F C Lemieux , L Pinheiro Carvalho , G El Hajj Boutros , M Bélanger , P Gaudreau , S Chevalier , J A Morais , P Noirez , G Gouspillou , M Aubertin-Leheudre

Drp1 knockdown induces severe muscle atrophy and remodelling, mitochondrial dysfunction, autophagy impairment and denervation.

The Journal of physiology

Avec: Maude Dulac , Jean-Philippe Leduc-Gaudet , Olivier Reynaud , Marie-Belle Ayoub , Amanda Guérin , Michel Finkelchtein , Sabah Na Hussain , Gilles Gouspillou

Wrist-worn devices for the measurement of heart rate and energy expenditure: A validation study for the Apple Watch 6, Polar Vantage V and Fitbit Sense.

European journal of sport science

Avec: Guy Hajj-Boutros , Marie-Anne Landry-Duval , Alain Steve Comtois , Gilles Gouspillou , Antony D Karelis

Quantitative Immunoblotting Analyses Reveal that the Abundance of Actin, Tubulin, Synaptophysin and EEA1 Proteins is Altered in the Brains of Aged Mice.

Neuroscience

Avec: Hou Ve , Valérie C Cabana , Gilles Gouspillou , Marc P Lussier

Impact of high-intensity interval training with or without l-citrulline on physical performance, skeletal muscle, and adipose tissue in obese older adults.

Journal of cachexia, sarcopenia and muscle

Avec: Vincent Marcangeli , Layale Youssef , Maude Dulac , Livia P Carvalho , Guy Hajj-Boutros , Olivier Reynaud , Bénédicte Guegan , Fanny Buckinx , Pierrette Gaudreau , José A Morais , Pascale Mauriège , Philippe Noirez , Mylène Aubertin-Leheudre , Gilles Gouspillou

Serum metabolomic adaptations following a 12-week high-intensity interval training combined to citrulline supplementation in obese older adults.

European journal of sport science

Avec: Layale Youssef , Sylvère Durand , Fanny Aprahamian , Deborah Lefevre , Mélanie Bourgin , Maria Chiara Maiuri , Maude Dulac , Guy Hajj-Boutros , Vincent Marcangeli , Fanny Buckinx , Eva Peyrusqué , José A Morais , Pierrette Gaudreau , Gilles Gouspillou , Guido Kroemer , Mylène Aubertin-Leheudre , Philippe Noirez

Effects of Aging and Caloric Restriction on Fiber Type Composition, Mitochondrial Morphology and Dynamics in Rat Oxidative and Glycolytic Muscles.

Frontiers in physiology

Avec: Julie Faitg , Jean-Philippe Leduc-Gaudet , Olivier Reynaud , Guylaine Ferland , Pierrette Gaudreau , Gilles Gouspillou

Initial Dietary Protein Intake Influence Muscle Function Adaptations in Older Men and Women Following High-Intensity Interval Training Combined with Citrulline.

Nutrients

Avec: Fanny Buckinx , Vincent Marcangeli , Lívia Pinheiro Carvalho , Maude Dulac , Guy Hajj Boutros , Gilles Gouspillou , Pierrette Gaudreau , José Morais , Philippe Noirez , Mylène Aubertin-Leheudre

Integrative Methods for Studying Cardiac Energetics.

Methods in molecular biology (Clifton, N.J.)

Avec: Philippe Diolez , Véronique Deschodt-Arsac , Guillaume Calmettes , Gilles Gouspillou , Laurent Arsac , Pierre Jais , Michel Haissaguerre , Pierre Dos Santos

MFN2 overexpression in skeletal muscles of young and old mice causes a mild hypertrophy without altering mitochondrial respiration and H

Acta physiologica (Oxford, England)

Avec: Marina Cefis , Manon Dargegen , Vincent Marcangeli , Shima Taherkhani , Maude Dulac , Jean-Philippe Leduc-Gaudet , Dominique Mayaki , Sabah N A Hussain , Gilles Gouspillou

Psychobiological regulation of plasma and saliva GDF15 dynamics in health and mitochondrial diseases.

bioRxiv : the preprint server for biology

Avec: Qiuhan Huang , Caroline Trumpff , Anna S Monzel , Shannon Rausser , Rachel Haahr , Jack Devine , Cynthia C Liu , Catherine Kelly , Elizabeth Thompson , Mangesh Kurade , Jeremy Michelson , Evan D Shaulson , Shufang Li , Kris Engelstad , Kurenai Tanji , Vincenzo Lauriola , Tian Wang , Shuang Wang , Faris M Zuraikat , Marie-Pierre St-Onge , Brett A Kaufman , Richard Sloan , Robert-Paul Juster , Anna L Marsland , Gilles Gouspillou , Michio Hirano , Martin Picard

Potential mechanisms involved in regulating muscle protein turnover after acute exercise: A brief review.

Frontiers in physiology

Avec: Guy Hajj-Boutros , Antony D Karelis , Marina Cefis , José A Morais , Juliette Casgrain , Gilles Gouspillou , Vita Sonjak

The impact of high-fat feeding and parkin overexpression on skeletal muscle mass, mitochondrial respiration, and H

American journal of physiology. Cell physiology

Avec: Olivier Reynaud , Jennifer Wang , Marie-Belle Ayoub , Jean-Philippe Leduc-Gaudet , Dominique Mayaki , Maude Dulac , Sabah N A Hussain , Raynald Bergeron , Gilles Gouspillou

PHAF1/MYTHO is a novel autophagy regulator that controls muscle integrity.

Autophagy

Avec: Anais Franco-Romero , Jean Philippe Leduc-Gaudet , Sabah Na Hussain , Gilles Gouspillou , Marco Sandri

Parkin overexpression protects from ageing-related loss of muscle mass and strength.

The Journal of physiology

Avec: Jean-Philippe Leduc-Gaudet , Olivier Reynaud , Sabah N Hussain , Gilles Gouspillou

Human studies of mitochondrial biology demonstrate an overall lack of binary sex differences: A multivariate meta-analysis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: Alex Junker , Jennifer Wang , Gilles Gouspillou , Johannes K Ehinger , Eskil Elmér , Fredrik Sjövall , Kelsey H Fisher-Wellman , P Darrell Neufer , Anthony J A Molina , Luigi Ferrucci , Martin Picard

Clinical and Biological Adaptations in Obese Older Adults Following 12-Weeks of High-Intensity Interval Training or Moderate-Intensity Continuous Training.

Healthcare (Basel, Switzerland)

Avec: Layale Youssef , Jordan Granet , Vincent Marcangeli , Maude Dulac , Guy Hajj-Boutros , Olivier Reynaud , Fanny Buckinx , Pierrette Gaudreau , José A Morais , Pascale Mauriège , Gilles Gouspillou , Philippe Noirez , Mylène Aubertin-Leheudre

Dynamic behavior of cell-free mitochondrial DNA in human saliva.

Psychoneuroendocrinology

Avec: Caroline Trumpff , Shannon Rausser , Rachel Haahr , Kalpita R Karan , Gilles Gouspillou , Eli Puterman , Clemens Kirschbaum , Martin Picard

Autophagy ablation in skeletal muscles worsens sepsis-induced muscle wasting, impairs whole-body metabolism, and decreases survival.

iScience

Avec: Jean-Philippe Leduc-Gaudet , Kayla Miguez , Marina Cefis , Julie Faitg , Alaa Moamer , Tomer Jordi Chaffer , Olivier Reynaud , Felipe E Broering , Anwar Shams , Dominique Mayaki , Laurent Huck , Marco Sandri , Gilles Gouspillou , Sabah N A Hussain

Serum Metabolome Adaptations Following 12 Weeks of High-Intensity Interval Training or Moderate-Intensity Continuous Training in Obese Older Adults.

Metabolites

Avec: Layale Youssef , Mélanie Bourgin , Sylvère Durand , Fanny Aprahamian , Deborah Lefevre , Maria Chiara Maiuri , Vincent Marcangeli , Maude Dulac , Guy Hajj-Boutros , Fanny Buckinx , Eva Peyrusqué , Pierrette Gaudreau , José A Morais , Gilles Gouspillou , Guido Kroemer , Mylène Aubertin-Leheudre , Philippe Noirez

Resistance training in women with myotonic dystrophy type 1: a multisystemic therapeutic avenue.

Neuromuscular disorders : NMD

Avec: Laura Girard-Côté , Benjamin Gallais , Cynthia Gagnon , Marie-Pier Roussel , Marika Morin , Luc J Hébert , Darren Monckton , Jean-Philippe Leduc-Gaudet , Gilles Gouspillou , Vincent Marcangeli , Elise Duchesne

A multimodal exercise countermeasure prevents the negative impact of head-down tilt bed rest on muscle volume and mitochondrial health in older adults.

The Journal of physiology

Avec: Maude Dulac , Guy Hajj-Boutros , Vita Sonjak , Andréa Faust , Sabah N A Hussain , Stéphanie Chevalier , Isabelle J Dionne , José A Morais , Gilles Gouspillou

Réseau de co-auteurs

Jean-Philippe Leduc-Gaudet 13 collaborations

Maude Dulac 11 collaborations

José A Morais 9 collaborations

Olivier Reynaud 9 collaborations

Guy Hajj-Boutros 8 collaborations

Vincent Marcangeli 8 collaborations

Sabah N A Hussain 7 collaborations

Dominique Mayaki 6 collaborations

Pierrette Gaudreau 6 collaborations

Marina Cefis 5 collaborations

Fanny Buckinx 5 collaborations

Philippe Noirez 5 collaborations

Mylène Aubertin-Leheudre 5 collaborations

Alaa Moamer 4 collaborations

Sabah Na Hussain 4 collaborations

Layale Youssef 4 collaborations

Felipe E Broering 3 collaborations

Marie-Belle Ayoub 3 collaborations

Anwar Shams 3 collaborations

Laurent Huck 3 collaborations

Marco Sandri 3 collaborations

Martin Picard 3 collaborations

Manon Dargegen 2 collaborations

Andréa Faust 2 collaborations

Stéphanie Chevalier 2 collaborations

Anais Franco-Romero 2 collaborations

Tomer Jordi Chaffer 2 collaborations

Elise Duchesne 2 collaborations

Antony D Karelis 2 collaborations

Pascale Mauriège 2 collaborations

Sylvère Durand 2 collaborations

Fanny Aprahamian 2 collaborations

Deborah Lefevre 2 collaborations

Mélanie Bourgin 2 collaborations

Maria Chiara Maiuri 2 collaborations

Eva Peyrusqué 2 collaborations

Guido Kroemer 2 collaborations

Julie Faitg 2 collaborations

Caroline Trumpff 2 collaborations

Shannon Rausser 2 collaborations

Rachel Haahr 2 collaborations

Vita Sonjak 2 collaborations

Jennifer Wang 2 collaborations

Esther Barreiro 1 collaboration

Sarkis J Hannaian 1 collaboration

Jamie Lov 1 collaboration

Stephanie E Hawley 1 collaboration

Divine Malenda 1 collaboration

Ari Gritsas 1 collaboration

Tyler A Churchward-Venne 1 collaboration

John Muscedere 1 collaboration

Perry Kim 1 collaboration

Naji Abumrad 1 collaboration

Mylene Aubertin-Leheudre 1 collaboration

Howard Bergman 1 collaboration

Dawn Bowdish 1 collaboration

Jessica Burford 1 collaboration

Stacy Carrington-Lawrence 1 collaboration

Hélène Côté 1 collaboration

David E Dawe 1 collaboration

Philipe de Souto Barreto 1 collaboration

Colin Farrelly 1 collaboration

Robert Fowler 1 collaboration

Lea Harrington 1 collaboration

Sofie Lautrup 1 collaboration

Susan Howlett 1 collaboration

Mahdi Imani 1 collaboration

James Kirkland 1 collaboration

George Kuchel 1 collaboration

Frédérick A Mallette 1 collaboration

John C Newman 1 collaboration

Daryl Pullman 1 collaboration

Felipe Sierra 1 collaboration

Jeremy Van Raamsdonk 1 collaboration

Jennifer Watt 1 collaboration

R Jane Rylett 1 collaboration

Gustavo Duque 1 collaboration

Tomer J Chaffer 1 collaboration

Marcos Francisco Nery Ferreira 1 collaboration

Giulia Milan 1 collaboration

Roberta Sartori 1 collaboration

Hanns Lochmuller 1 collaboration

Sami Sedraoui 1 collaboration

Basil J Petrof 1 collaboration

Sabah Hussain 1 collaboration

M C Dulac 1 collaboration

C H Pion 1 collaboration

F C Lemieux 1 collaboration

L Pinheiro Carvalho 1 collaboration

G El Hajj Boutros 1 collaboration

M Bélanger 1 collaboration

P Gaudreau 1 collaboration

S Chevalier 1 collaboration

J A Morais 1 collaboration

P Noirez 1 collaboration

G Gouspillou 1 collaboration

M Aubertin-Leheudre 1 collaboration

Amanda Guérin 1 collaboration

Michel Finkelchtein 1 collaboration

Marie-Anne Landry-Duval 1 collaboration

Alain Steve Comtois 1 collaboration

Hou Ve 1 collaboration

Valérie C Cabana 1 collaboration

Marc P Lussier 1 collaboration

Livia P Carvalho 1 collaboration

Bénédicte Guegan 1 collaboration

Guylaine Ferland 1 collaboration

Lívia Pinheiro Carvalho 1 collaboration

Guy Hajj Boutros 1 collaboration

José Morais 1 collaboration

Philippe Diolez 1 collaboration

Véronique Deschodt-Arsac 1 collaboration

Guillaume Calmettes 1 collaboration

Laurent Arsac 1 collaboration

Pierre Jais 1 collaboration

Michel Haissaguerre 1 collaboration

Pierre Dos Santos 1 collaboration

Shima Taherkhani 1 collaboration

Qiuhan Huang 1 collaboration

Anna S Monzel 1 collaboration

Jack Devine 1 collaboration

Cynthia C Liu 1 collaboration

Catherine Kelly 1 collaboration

Elizabeth Thompson 1 collaboration

Mangesh Kurade 1 collaboration

Jeremy Michelson 1 collaboration

Evan D Shaulson 1 collaboration

Shufang Li 1 collaboration

Kris Engelstad 1 collaboration

Kurenai Tanji 1 collaboration

Vincenzo Lauriola 1 collaboration

Tian Wang 1 collaboration

Shuang Wang 1 collaboration

Faris M Zuraikat 1 collaboration

Marie-Pierre St-Onge 1 collaboration

Brett A Kaufman 1 collaboration

Richard Sloan 1 collaboration

Robert-Paul Juster 1 collaboration

Anna L Marsland 1 collaboration

Michio Hirano 1 collaboration

Juliette Casgrain 1 collaboration

Raynald Bergeron 1 collaboration

Jean Philippe Leduc-Gaudet 1 collaboration

Sabah N Hussain 1 collaboration

Alex Junker 1 collaboration

Johannes K Ehinger 1 collaboration

Eskil Elmér 1 collaboration

Fredrik Sjövall 1 collaboration

Kelsey H Fisher-Wellman 1 collaboration

P Darrell Neufer 1 collaboration

Anthony J A Molina 1 collaboration

Luigi Ferrucci 1 collaboration

Jordan Granet 1 collaboration

Kalpita R Karan 1 collaboration

Eli Puterman 1 collaboration

Clemens Kirschbaum 1 collaboration

Kayla Miguez 1 collaboration

Laura Girard-Côté 1 collaboration

Benjamin Gallais 1 collaboration

Cynthia Gagnon 1 collaboration

Marie-Pier Roussel 1 collaboration

Marika Morin 1 collaboration

Luc J Hébert 1 collaboration

Darren Monckton 1 collaboration

Isabelle J Dionne 1 collaboration