Sofie Lautrup

Affiliations

Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, 1478 Lørenskog, Norway.

Publications (20)

Targeting NAD

Mechanisms of ageing and development

Avec: Brian C Gilmour , Ruben Gudmundsrud , Johannes Frank , Amund Hov , Yahyah Aman , Helge Røsjø , Charles Brenner , Mathias Ziegler , Ole-Bjørn Tysnes , Charalampos Tzoulis , Torbjørn Omland , Arne Søraas , Trygve Holmøy , Linda H Bergersen , Jon Storm-Mathisen , Hilde Nilsen , Evandro F Fang

NAD

Nature communications

Avec: Evandro F Fang , Yujun Hou , Martin Borch Jensen , Beimeng Yang , Tanima SenGupta , Domenica Caponio , Rojyar Khezri , Tyler G Demarest , Yahyah Aman , David Figueroa , Marya Morevati , Ho-Joon Lee , Hisaya Kato , Henok Kassahun , Jong-Hyuk Lee , Deborah Filippelli , Mustafa Nazir Okur , Aswin Mangerich , Deborah L Croteau , Yoshiro Maezawa , Costas A Lyssiotis , Jun Tao , Koutaro Yokote , Tor Erik Rusten , Mark P Mattson , Heinrich Jasper , Hilde Nilsen , Vilhelm A Bohr

The role of aging and brain-derived neurotrophic factor signaling in expression of base excision repair genes in the human brain.

Aging cell

Avec: Camilla Myrup Holst , Anne Yde , Stine Asmussen , Vibeke Thinggaard , Knud Larsen , Lisbeth Schmidt Laursen , Mette Richner , Christian B Vaegter , G Aleph Prieto , Nicole Berchtold , Carl W Cotman , Tinna Stevnsner

Crosstalk among DNA Damage, Mitochondrial Dysfunction, Impaired Mitophagy, Stem Cell Attrition, and Senescence in the Accelerated Ageing Disorder Werner Syndrome.

Cytogenetic and genome research

Avec: Ruben Gudmundsrud , Tarjei H Skjånes , Brian C Gilmour , Domenica Caponio , Evandro F Fang

Phosphorylation of the Human DNA Glycosylase NEIL2 Is Affected by Oxidative Stress and Modulates Its Activity.

Antioxidants (Basel, Switzerland)

Avec: Camilla Myrup Holst , Nanna Brøndum Andersen , Vibeke Thinggaard , Mine Tilken , Cinzia Tesauro , Tinna Stevnsner

DNA Damage-Induced Neurodegeneration in Accelerated Ageing and Alzheimer's Disease.

International journal of molecular sciences

Avec: Heling Wang , Domenica Caponio , Jianying Zhang , Evandro F Fang

New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary.

Aging

Avec: Tomas Schmauck-Medina , Adrian Molière , Jianying Zhang , Stefan Chlopicki , Helena Borland Madsen , Shuqin Cao , Casper Soendenbroe , Els Mansell , Mark Bitsch Vestergaard , Zhiquan Li , Yosef Shiloh , Patricia L Opresko , Jean-Marc Egly , Thomas Kirkwood , Eric Verdin , Vilhelm A Bohr , Lynne S Cox , Tinna Stevnsner , Lene Juel Rasmussen , Evandro F Fang

Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions.

The journals of gerontology. Series A, Biological sciences and medical sciences

Avec: Guy Hajj-Boutros , Andréa Faust , John Muscedere , Perry Kim , Naji Abumrad , Stéphanie Chevalier , Mylene Aubertin-Leheudre , Howard Bergman , Dawn Bowdish , Jessica Burford , Stacy Carrington-Lawrence , Hélène Côté , David E Dawe , Philipe de Souto Barreto , Colin Farrelly , Robert Fowler , Gilles Gouspillou , Lea Harrington , Susan Howlett , Mahdi Imani , James Kirkland , George Kuchel , Frédérick A Mallette , José A Morais , John C Newman , Daryl Pullman , Felipe Sierra , Jeremy Van Raamsdonk , Jennifer Watt , R Jane Rylett , Gustavo Duque

NAD

Cell metabolism

Avec: David A Sinclair , Mark P Mattson , Evandro F Fang

Mitophagy and Neuroprotection.

Trends in molecular medicine

Avec: Guofeng Lou , Konstantinos Palikaras , Morten Scheibye-Knudsen , Nektarios Tavernarakis , Evandro F Fang

Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases.

Biogerontology

Avec: Domenica Caponio , Hoi-Hung Cheung , Claudia Piccoli , Tinna Stevnsner , Wai-Yee Chan , Evandro F Fang

Amelioration of Alzheimer's disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow.

Nature biomedical engineering

Avec: Chenglong Xie , Xu-Xu Zhuang , Zhangming Niu , Ruixue Ai , Shuangjia Zheng , Yinghui Jiang , Ruiyu Han , Tanima Sen Gupta , Shuqin Cao , Maria Jose Lagartos-Donate , Cui-Zan Cai , Li-Ming Xie , Domenica Caponio , Wen-Wen Wang , Tomas Schmauck-Medina , Jianying Zhang , He-Ling Wang , Guofeng Lou , Xianglu Xiao , Wenhua Zheng , Konstantinos Palikaras , Guang Yang , Kim A Caldwell , Guy A Caldwell , Han-Ming Shen , Hilde Nilsen , Jia-Hong Lu , Evandro F Fang

Meeting summary of The NYO3 5th NO-Age/AD meeting and the 1st Norway-UK joint meeting on ageing and dementia: recent progress on the mechanisms and interventional strategies.

The journals of gerontology. Series A, Biological sciences and medical sciences

Avec: He-Ling Wang , Richard Siow , Tomas Schmauck-Medina , Jianying Zhang , Per Morten Sandset , Clare Filshie , Øystein Lund , Linda Partridge , Linda Hildegard Bergersen , Lene Juel Rasmussen , Konstantinos Palikaras , Ioannis Sotiropoulos , Jon Storm-Mathisen , David C Rubinsztein , Maria Grazia Spillantini , Chris I De Zeeuw , Leiv Otto Watne , Martin Vyhnalek , Katerina Veverova , Kristina Xiao Liang , Nektarios Tavernarakis , Vilhelm A Bohr , Koutaro Yokote , Janna Saarela , Hilde Nilsen , Efstathios S Gonos , Morten Scheibye-Knudsen , Guobing Chen , Hisaya Kato , Geir Selbæk , Tormod Fladby , Per Nilsson , Anne Simonsen , Dag Aarsland , Ole Petter Ottersen , Lynne S Cox , Evandro F Fang

Microglial mitophagy mitigates neuroinflammation in Alzheimer's disease.

Neurochemistry international

Avec: Guofeng Lou , Yahyah Aman , Hilde Nilsen , Jun Tao , Evandro F Fang

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.

Nature neuroscience

Avec: Evandro F Fang , Yujun Hou , Konstantinos Palikaras , Bryan A Adriaanse , Jesse S Kerr , Beimeng Yang , Md Mahdi Hasan-Olive , Domenica Caponio , Xiuli Dan , Paula Rocktäschel , Deborah L Croteau , Mansour Akbari , Nigel H Greig , Tormod Fladby , Hilde Nilsen , M Zameel Cader , Mark P Mattson , Nektarios Tavernarakis , Vilhelm A Bohr

NAD

Proceedings of the National Academy of Sciences of the United States of America

Avec: Yujun Hou , Yong Wei , Beimeng Yang , Yue Wang , Stephanie Cordonnier , Mark P Mattson , Deborah L Croteau , Vilhelm A Bohr

WRN loss accelerates abnormal adipocyte metabolism in Werner syndrome.

Cell & bioscience

Avec: Yuyao Tian , Patrick Wai Nok Law , Ngoc-Duy Dinh , Evandro Fei Fang , Wai-Yee Chan

WRN promotes bone development and growth by unwinding SHOX-G-quadruplexes via its helicase activity in Werner Syndrome.

Nature communications

Avec: Yuyao Tian , Wuming Wang , Hui Zhao , Xiang Li , Patrick Wai Nok Law , Ngoc-Duy Dinh , Evandro Fei Fang , Hoi Hung Cheung , Wai-Yee Chan

Roles of NAD

Cold Spring Harbor perspectives in medicine

Avec: Yujun Hou , Evandro F Fang , Vilhelm A Bohr

A comprehensive AI-driven analysis of large-scale omic datasets reveals novel dual-purpose targets for the treatment of cancer and aging.

Aging cell

Avec: Frank W Pun , Geoffrey Ho Duen Leung , Hoi Wing Leung , Jared Rice , Tomas Schmauck-Medina , Xi Long , Bonnie Hei Man Liu , Chun Wai Wong , Ivan V Ozerov , Alex Aliper , Feng Ren , Ari J Rosenberg , Nishant Agrawal , Evgeny Izumchenko , Evandro F Fang , Alex Zhavoronkov

Réseau de co-auteurs

Evandro F Fang 14 collaborations

Hilde Nilsen 6 collaborations

Domenica Caponio 6 collaborations

Vilhelm A Bohr 6 collaborations

Yujun Hou 4 collaborations

Mark P Mattson 4 collaborations

Tinna Stevnsner 4 collaborations

Jianying Zhang 4 collaborations

Tomas Schmauck-Medina 4 collaborations

Konstantinos Palikaras 4 collaborations

Yahyah Aman 3 collaborations

Beimeng Yang 3 collaborations

Deborah L Croteau 3 collaborations

Guofeng Lou 3 collaborations

Nektarios Tavernarakis 3 collaborations

Wai-Yee Chan 3 collaborations

Brian C Gilmour 2 collaborations

Ruben Gudmundsrud 2 collaborations

Jon Storm-Mathisen 2 collaborations

Hisaya Kato 2 collaborations

Jun Tao 2 collaborations

Koutaro Yokote 2 collaborations

Camilla Myrup Holst 2 collaborations

Vibeke Thinggaard 2 collaborations

Shuqin Cao 2 collaborations

Lynne S Cox 2 collaborations

Lene Juel Rasmussen 2 collaborations

Morten Scheibye-Knudsen 2 collaborations

He-Ling Wang 2 collaborations

Tormod Fladby 2 collaborations

Yuyao Tian 2 collaborations

Patrick Wai Nok Law 2 collaborations

Ngoc-Duy Dinh 2 collaborations

Evandro Fei Fang 2 collaborations

Johannes Frank 1 collaboration

Amund Hov 1 collaboration

Helge Røsjø 1 collaboration

Charles Brenner 1 collaboration

Mathias Ziegler 1 collaboration

Ole-Bjørn Tysnes 1 collaboration

Charalampos Tzoulis 1 collaboration

Torbjørn Omland 1 collaboration

Arne Søraas 1 collaboration

Trygve Holmøy 1 collaboration

Linda H Bergersen 1 collaboration

Martin Borch Jensen 1 collaboration

Tanima SenGupta 1 collaboration

Rojyar Khezri 1 collaboration

Tyler G Demarest 1 collaboration

David Figueroa 1 collaboration

Marya Morevati 1 collaboration

Ho-Joon Lee 1 collaboration

Henok Kassahun 1 collaboration

Jong-Hyuk Lee 1 collaboration

Deborah Filippelli 1 collaboration

Mustafa Nazir Okur 1 collaboration

Aswin Mangerich 1 collaboration

Yoshiro Maezawa 1 collaboration

Costas A Lyssiotis 1 collaboration

Tor Erik Rusten 1 collaboration

Heinrich Jasper 1 collaboration

Anne Yde 1 collaboration

Stine Asmussen 1 collaboration

Knud Larsen 1 collaboration

Lisbeth Schmidt Laursen 1 collaboration

Mette Richner 1 collaboration

Christian B Vaegter 1 collaboration

G Aleph Prieto 1 collaboration

Nicole Berchtold 1 collaboration

Carl W Cotman 1 collaboration

Tarjei H Skjånes 1 collaboration

Nanna Brøndum Andersen 1 collaboration

Mine Tilken 1 collaboration

Cinzia Tesauro 1 collaboration

Heling Wang 1 collaboration

Adrian Molière 1 collaboration

Stefan Chlopicki 1 collaboration

Helena Borland Madsen 1 collaboration

Casper Soendenbroe 1 collaboration

Els Mansell 1 collaboration

Mark Bitsch Vestergaard 1 collaboration

Zhiquan Li 1 collaboration

Yosef Shiloh 1 collaboration

Patricia L Opresko 1 collaboration

Jean-Marc Egly 1 collaboration

Thomas Kirkwood 1 collaboration

Eric Verdin 1 collaboration

Guy Hajj-Boutros 1 collaboration

Andréa Faust 1 collaboration

John Muscedere 1 collaboration

Perry Kim 1 collaboration

Naji Abumrad 1 collaboration

Stéphanie Chevalier 1 collaboration

Mylene Aubertin-Leheudre 1 collaboration

Howard Bergman 1 collaboration

Dawn Bowdish 1 collaboration

Jessica Burford 1 collaboration

Stacy Carrington-Lawrence 1 collaboration

Hélène Côté 1 collaboration

David E Dawe 1 collaboration

Philipe de Souto Barreto 1 collaboration

Colin Farrelly 1 collaboration

Robert Fowler 1 collaboration

Gilles Gouspillou 1 collaboration

Lea Harrington 1 collaboration

Susan Howlett 1 collaboration

Mahdi Imani 1 collaboration

James Kirkland 1 collaboration

George Kuchel 1 collaboration

Frédérick A Mallette 1 collaboration

José A Morais 1 collaboration

John C Newman 1 collaboration

Daryl Pullman 1 collaboration

Felipe Sierra 1 collaboration

Jeremy Van Raamsdonk 1 collaboration

Jennifer Watt 1 collaboration

R Jane Rylett 1 collaboration

Gustavo Duque 1 collaboration

David A Sinclair 1 collaboration

Hoi-Hung Cheung 1 collaboration

Claudia Piccoli 1 collaboration

Chenglong Xie 1 collaboration

Xu-Xu Zhuang 1 collaboration

Zhangming Niu 1 collaboration

Ruixue Ai 1 collaboration

Shuangjia Zheng 1 collaboration

Yinghui Jiang 1 collaboration

Ruiyu Han 1 collaboration

Tanima Sen Gupta 1 collaboration

Maria Jose Lagartos-Donate 1 collaboration

Cui-Zan Cai 1 collaboration

Li-Ming Xie 1 collaboration

Wen-Wen Wang 1 collaboration

Xianglu Xiao 1 collaboration

Wenhua Zheng 1 collaboration

Guang Yang 1 collaboration

Kim A Caldwell 1 collaboration

Guy A Caldwell 1 collaboration

Han-Ming Shen 1 collaboration

Jia-Hong Lu 1 collaboration

Richard Siow 1 collaboration

Per Morten Sandset 1 collaboration

Clare Filshie 1 collaboration

Øystein Lund 1 collaboration

Linda Partridge 1 collaboration

Linda Hildegard Bergersen 1 collaboration

Ioannis Sotiropoulos 1 collaboration

David C Rubinsztein 1 collaboration

Maria Grazia Spillantini 1 collaboration

Chris I De Zeeuw 1 collaboration

Leiv Otto Watne 1 collaboration

Martin Vyhnalek 1 collaboration

Katerina Veverova 1 collaboration

Kristina Xiao Liang 1 collaboration

Janna Saarela 1 collaboration

Efstathios S Gonos 1 collaboration

Guobing Chen 1 collaboration

Geir Selbæk 1 collaboration

Per Nilsson 1 collaboration

Anne Simonsen 1 collaboration

Dag Aarsland 1 collaboration

Ole Petter Ottersen 1 collaboration

Bryan A Adriaanse 1 collaboration

Jesse S Kerr 1 collaboration

Md Mahdi Hasan-Olive 1 collaboration

Xiuli Dan 1 collaboration

Paula Rocktäschel 1 collaboration

Mansour Akbari 1 collaboration

Nigel H Greig 1 collaboration

M Zameel Cader 1 collaboration

Yong Wei 1 collaboration

Yue Wang 1 collaboration

Stephanie Cordonnier 1 collaboration

Wuming Wang 1 collaboration

Hui Zhao 1 collaboration

Xiang Li 1 collaboration

Hoi Hung Cheung 1 collaboration

Frank W Pun 1 collaboration

Geoffrey Ho Duen Leung 1 collaboration

Hoi Wing Leung 1 collaboration

Jared Rice 1 collaboration

Xi Long 1 collaboration

Bonnie Hei Man Liu 1 collaboration

Chun Wai Wong 1 collaboration

Ivan V Ozerov 1 collaboration

Alex Aliper 1 collaboration

Feng Ren 1 collaboration

Ari J Rosenberg 1 collaboration

Nishant Agrawal 1 collaboration

Evgeny Izumchenko 1 collaboration

Alex Zhavoronkov 1 collaboration