George A Truskey

Affiliations

Department of Biomedical Engineering, Duke University, 1427 CIEMAS, 101 Science Drive, Durham, NC 27708-0281, USA.

Publications (30)

Vascular Microphysiological Systems to Model Diseases.

Cell & gene therapy insights

Avec: Qiao Zhang , Xu Zhang , George A Truskey

Chemotherapeutic drug screening in 3D-Bioengineered human myobundles provides insight into taxane-induced myotoxicities.

iScience

Avec: Maria J Torres , Xu Zhang , Dorothy H Slentz , Timothy R Koves , Hailee Patel , George A Truskey , Deborah M Muoio

Lonafarnib and everolimus reduce pathology in iPSC-derived tissue engineered blood vessel model of Hutchinson-Gilford Progeria Syndrome.

Scientific reports

Avec: Nadia O Abutaleb , Leigh Atchison , Leandro Choi , Akhil Bedapudi , Kevin Shores , Yantenew Gete , Kan Cao , George A Truskey

Mechanotransduction of the vasculature in Hutchinson-Gilford Progeria Syndrome.

Frontiers in physiology

Avec: Kevin L Shores , George A Truskey

Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation.

Cells

Avec: Ellen E Salmon , Jason J Breithaupt , George A Truskey

Oxygen consumption in human, tissue-engineered myobundles during basal and electrical stimulation conditions.

APL bioengineering

Avec: Brittany N Davis , Ringo Yen , Varun Prasad , George A Truskey

Development and Application of Endothelial Cells Derived From Pluripotent Stem Cells in Microphysiological Systems Models.

Frontiers in cardiovascular medicine

Avec: Crystal C Kennedy , Erin E Brown , Nadia O Abutaleb , George A Truskey

Principles for the design of multicellular engineered living systems.

APL bioengineering

Avec: Onur Aydin , Austin P Passaro , Ritu Raman , Samantha E Spellicy , Robert P Weinberg , Roger D Kamm , Matthew Sample , George A Truskey , Jeremiah Zartman , Roy D Dar , Sebastian Palacios , Jason Wang , Jesse Tordoff , Nuria Montserrat , Rashid Bashir , M Taher A Saif , Ron Weiss

iPSC-Derived Endothelial Cells Affect Vascular Function in a Tissue-Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome.

Stem cell reports

Avec: Leigh Atchison , Nadia O Abutaleb , Elizabeth Snyder-Mounts , Yantenew Gete , Alim Ladha , Thomas Ribar , Kan Cao , George A Truskey

Modeling the Effect of TNF-α upon Drug-Induced Toxicity in Human, Tissue-Engineered Myobundles.

Annals of biomedical engineering

Avec: Brittany N J Davis , Jeffrey W Santoso , Michaela J Walker , Catherine E Oliver , Michael M Cunningham , Christian A Boehm , Danielle Dawes , Samantha L Lasater , Kim Huffman , William E Kraus , George A Truskey

The NIH Somatic Cell Genome Editing program.

Nature

Avec: Krishanu Saha , Erik J Sontheimer , P J Brooks , Melinda R Dwinell , Charles A Gersbach , David R Liu , Stephen A Murray , Shengdar Q Tsai , Ross C Wilson , Daniel G Anderson , Aravind Asokan , Jillian F Banfield , Krystof S Bankiewicz , Gang Bao , Jeff W M Bulte , Nenad Bursac , Jarryd M Campbell , Daniel F Carlson , Elliot L Chaikof , Zheng-Yi Chen , R Holland Cheng , Karl J Clark , David T Curiel , James E Dahlman , Benjamin E Deverman , Mary E Dickinson , Jennifer A Doudna , Stephen C Ekker , Marina E Emborg , Guoping Feng , Benjamin S Freedman , David M Gamm , Guangping Gao , Ionita C Ghiran , Peter M Glazer , Shaoqin Gong , Jason D Heaney , Jon D Hennebold , John T Hinson , Anastasia Khvorova , Samira Kiani , William R Lagor , Kit S Lam , Kam W Leong , Jon E Levine , Jennifer A Lewis , Cathleen M Lutz , Danith H Ly , Samantha Maragh , Paul B McCray , Todd C McDevitt , Oleg Mirochnitchenko , Ryuji Morizane , Niren Murthy , Randall S Prather , John A Ronald , Subhojit Roy , Sushmita Roy , Venkata Sabbisetti , W Mark Saltzman , Philip J Santangelo , David J Segal , Mary Shimoyama , Melissa C Skala , Alice F Tarantal , John C Tilton , George A Truskey , Moriel Vandsburger , Jonathan K Watts , Kevin D Wells , Scot A Wolfe , Qiaobing Xu , Wen Xue , Guohua Yi , Jiangbing Zhou , Auteur inconnu

Late onset cardiovascular dysfunction in adult mice resulting from galactic cosmic ray exposure.

iScience

Avec: Muath Bishawi , Franklin H Lee , Dennis M Abraham , Carolyn Glass , Stephanie J Blocker , Daniel J Cox , Zachary D Brown , Howard A Rockman , Lan Mao , Tony C Slaba , Mark W Dewhirst , George A Truskey , Dawn E Bowles

PCSK9 activation promotes early atherosclerosis in a vascular microphysiological system.

APL bioengineering

Avec: Jounghyun H Lee , Kevin L Shores , Jason J Breithaupt , Caleb S Lee , Daniella M Fodera , Jennifer B Kwon , Adarsh R Ettyreddy , Kristin M Myers , Benny J Evison , Alexandra K Suchowerska , Charles A Gersbach , Kam W Leong , George A Truskey

The Potential of Deep Learning to Advance Clinical Applications of Computational Biomechanics.

Bioengineering (Basel, Switzerland)

Avec: George A Truskey

Tissue engineered skeletal muscle model of rheumatoid arthritis using human primary skeletal muscle cells.

Journal of tissue engineering and regenerative medicine

Avec: Catherine E Oliver , Hailee Patel , James Hong , Jonathan Carter , William E Kraus , Kim M Huffman , George A Truskey

Differentiation and characterization of human iPSC-derived vascular endothelial cells under physiological shear stress.

STAR protocols

Avec: Nadia O Abutaleb , George A Truskey

Modeling statin myopathy in a human skeletal muscle microphysiological system.

PloS one

Avec: Anandita Ananthakumar , Yiling Liu , Cristina E Fernandez , George A Truskey , Deepak Voora

Effect of type I interferon on engineered pediatric skeletal muscle: A promising model for juvenile dermatomyositis.

Rheumatology (Oxford, England)

Avec: Lauren T Covert , Hailee Patel , Alaa Osman , Lavonia Duncan , Jeffrey Dvergsten , George A Truskey

Multi-Cellular Engineered Living Systems to Assess Reproductive Toxicology.

Reproductive toxicology (Elmsford, N.Y.)

Avec: Isabella Lopez , George A Truskey

Ammonia transporter RhBG initiates downstream signaling and functional responses by activating NFκB.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Saurabh Mishra , Nicole Welch , Shashi Shekhar Singh , Khuraijam Dhanachandra Singh , Annette Bellar , Avinash Kumar , Lars N Deutz , Maxmillian D Hanlon , Sashi Kant , Sumitava Dastidar , Hailee Patel , Vandana Agrawal , Amy H Attaway , Ryan Musich , George R Stark , Francesco Saverio Tedesco , George A Truskey , I David Weiner , Sadashiva S Karnik , Srinivasan Dasarathy

Glucose Uptake and Insulin Response in Tissue-engineered Human Skeletal Muscle.

Tissue engineering and regenerative medicine

Avec: Megan E Kondash , Anandita Ananthakumar , Alastair Khodabukus , Nenad Bursac , George A Truskey

Human iPSCs Stretch to Improve Tissue-Engineered Vascular Grafts.

Cell stem cell

Avec: Nadia O Abutaleb , George A Truskey

In Situ Fabrication and Perfusion of Tissue-Engineered Blood Vessel Microphysiological System.

Methods in molecular biology (Clifton, N.J.)

Avec: Xu Zhang , Nadia O Abutaleb , Ellen Salmon , George A Truskey

Modeling early stage atherosclerosis in a primary human vascular microphysiological system.

Nature communications

Avec: Xu Zhang , Muath Bishawi , Ge Zhang , Varun Prasad , Ellen Salmon , Jason J Breithaupt , Qiao Zhang , George A Truskey

Biofabrication of tissue engineering vascular systems.

APL bioengineering

Avec: Qiao Zhang , Èlia Bosch-Rué , Román A Pérez , George A Truskey

Differential microRNA profiles of intramuscular and secreted extracellular vesicles in human tissue-engineered muscle.

Frontiers in physiology

Avec: Christopher G Vann , Xin Zhang , Alastair Khodabukus , Melissa C Orenduff , Yu-Hsiu Chen , David L Corcoran , George A Truskey , Nenad Bursac , Virginia B Kraus

Genetic changes from type I interferons and JAK inhibitors: clues to drivers of juvenile dermatomyositis.

Rheumatology (Oxford, England)

Avec: Lauren T Covert , Joseph A Prinz , Devjanee Swain-Lenz , Jeffrey Dvergsten , George A Truskey

Bioengineered Model of Human LGMD2B Skeletal Muscle Reveals Roles of Intracellular Calcium Overload in Contractile and Metabolic Dysfunction in Dysferlinopathy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Avec: Alastair Khodabukus , Neel K Prabhu , Taylor Roberts , Meghan Buldo , Amber Detwiler , Zachary D Fralish , Megan E Kondash , George A Truskey , Timothy R Koves , Nenad Bursac

Angiopoietin-2 reverses endothelial cell dysfunction in progeria vasculature.

Aging cell

Avec: Sahar Vakili , Elizabeth K Izydore , Leonhard Losert , Wayne A Cabral , Urraca L Tavarez , Kevin Shores , Huijing Xue , Michael R Erdos , George A Truskey , Francis S Collins , Kan Cao

Interferon-β-Induced Injury During Pediatric Muscle Differentiation: Insight Into Juvenile Dermatomyositis Pathogenesis.

ACR open rheumatology

Avec: Lauren T Covert , Alaa Osman , George A Truskey

Réseau de co-auteurs

Nadia O Abutaleb 6 collaborations

Xu Zhang 4 collaborations

Hailee Patel 4 collaborations

Nenad Bursac 4 collaborations

Qiao Zhang 3 collaborations

Kan Cao 3 collaborations

Jason J Breithaupt 3 collaborations

Lauren T Covert 3 collaborations

Alastair Khodabukus 3 collaborations

Timothy R Koves 2 collaborations

Leigh Atchison 2 collaborations

Kevin Shores 2 collaborations

Yantenew Gete 2 collaborations

Kevin L Shores 2 collaborations

Varun Prasad 2 collaborations

Catherine E Oliver 2 collaborations

William E Kraus 2 collaborations

Charles A Gersbach 2 collaborations

Kam W Leong 2 collaborations

Muath Bishawi 2 collaborations

Anandita Ananthakumar 2 collaborations

Alaa Osman 2 collaborations

Jeffrey Dvergsten 2 collaborations

Megan E Kondash 2 collaborations

Ellen Salmon 2 collaborations

Maria J Torres 1 collaboration

Dorothy H Slentz 1 collaboration

Deborah M Muoio 1 collaboration

Leandro Choi 1 collaboration

Akhil Bedapudi 1 collaboration

Ellen E Salmon 1 collaboration

Brittany N Davis 1 collaboration

Ringo Yen 1 collaboration

Crystal C Kennedy 1 collaboration

Erin E Brown 1 collaboration

Onur Aydin 1 collaboration

Austin P Passaro 1 collaboration

Ritu Raman 1 collaboration

Samantha E Spellicy 1 collaboration

Robert P Weinberg 1 collaboration

Roger D Kamm 1 collaboration

Matthew Sample 1 collaboration

Jeremiah Zartman 1 collaboration

Roy D Dar 1 collaboration

Sebastian Palacios 1 collaboration

Jason Wang 1 collaboration

Jesse Tordoff 1 collaboration

Nuria Montserrat 1 collaboration

Rashid Bashir 1 collaboration

M Taher A Saif 1 collaboration

Ron Weiss 1 collaboration

Elizabeth Snyder-Mounts 1 collaboration

Alim Ladha 1 collaboration

Thomas Ribar 1 collaboration

Brittany N J Davis 1 collaboration

Jeffrey W Santoso 1 collaboration

Michaela J Walker 1 collaboration

Michael M Cunningham 1 collaboration

Christian A Boehm 1 collaboration

Danielle Dawes 1 collaboration

Samantha L Lasater 1 collaboration

Kim Huffman 1 collaboration

Krishanu Saha 1 collaboration

Erik J Sontheimer 1 collaboration

P J Brooks 1 collaboration

Melinda R Dwinell 1 collaboration

David R Liu 1 collaboration

Stephen A Murray 1 collaboration

Shengdar Q Tsai 1 collaboration

Ross C Wilson 1 collaboration

Daniel G Anderson 1 collaboration

Aravind Asokan 1 collaboration

Jillian F Banfield 1 collaboration

Krystof S Bankiewicz 1 collaboration

Gang Bao 1 collaboration

Jeff W M Bulte 1 collaboration

Jarryd M Campbell 1 collaboration

Daniel F Carlson 1 collaboration

Elliot L Chaikof 1 collaboration

Zheng-Yi Chen 1 collaboration

R Holland Cheng 1 collaboration

Karl J Clark 1 collaboration

David T Curiel 1 collaboration

James E Dahlman 1 collaboration

Benjamin E Deverman 1 collaboration

Mary E Dickinson 1 collaboration

Jennifer A Doudna 1 collaboration

Stephen C Ekker 1 collaboration

Marina E Emborg 1 collaboration

Guoping Feng 1 collaboration

Benjamin S Freedman 1 collaboration

David M Gamm 1 collaboration

Guangping Gao 1 collaboration

Ionita C Ghiran 1 collaboration

Peter M Glazer 1 collaboration

Shaoqin Gong 1 collaboration

Jason D Heaney 1 collaboration

Jon D Hennebold 1 collaboration

John T Hinson 1 collaboration

Anastasia Khvorova 1 collaboration

Samira Kiani 1 collaboration

William R Lagor 1 collaboration

Kit S Lam 1 collaboration

Jon E Levine 1 collaboration

Jennifer A Lewis 1 collaboration

Cathleen M Lutz 1 collaboration

Danith H Ly 1 collaboration

Samantha Maragh 1 collaboration

Paul B McCray 1 collaboration

Todd C McDevitt 1 collaboration

Oleg Mirochnitchenko 1 collaboration

Ryuji Morizane 1 collaboration

Niren Murthy 1 collaboration

Randall S Prather 1 collaboration

John A Ronald 1 collaboration

Subhojit Roy 1 collaboration

Sushmita Roy 1 collaboration

Venkata Sabbisetti 1 collaboration

W Mark Saltzman 1 collaboration

Philip J Santangelo 1 collaboration

David J Segal 1 collaboration

Mary Shimoyama 1 collaboration

Melissa C Skala 1 collaboration

Alice F Tarantal 1 collaboration

John C Tilton 1 collaboration

Moriel Vandsburger 1 collaboration

Jonathan K Watts 1 collaboration

Kevin D Wells 1 collaboration

Scot A Wolfe 1 collaboration

Qiaobing Xu 1 collaboration

Wen Xue 1 collaboration

Guohua Yi 1 collaboration

Jiangbing Zhou 1 collaboration

None None 1 collaboration

Franklin H Lee 1 collaboration

Dennis M Abraham 1 collaboration

Carolyn Glass 1 collaboration

Stephanie J Blocker 1 collaboration

Daniel J Cox 1 collaboration

Zachary D Brown 1 collaboration

Howard A Rockman 1 collaboration

Lan Mao 1 collaboration

Tony C Slaba 1 collaboration

Mark W Dewhirst 1 collaboration

Dawn E Bowles 1 collaboration

Jounghyun H Lee 1 collaboration

Caleb S Lee 1 collaboration

Daniella M Fodera 1 collaboration

Jennifer B Kwon 1 collaboration

Adarsh R Ettyreddy 1 collaboration

Kristin M Myers 1 collaboration

Benny J Evison 1 collaboration

Alexandra K Suchowerska 1 collaboration

James Hong 1 collaboration

Jonathan Carter 1 collaboration

Kim M Huffman 1 collaboration

Yiling Liu 1 collaboration

Cristina E Fernandez 1 collaboration

Deepak Voora 1 collaboration

Lavonia Duncan 1 collaboration

Isabella Lopez 1 collaboration

Saurabh Mishra 1 collaboration

Nicole Welch 1 collaboration

Shashi Shekhar Singh 1 collaboration

Khuraijam Dhanachandra Singh 1 collaboration

Annette Bellar 1 collaboration

Avinash Kumar 1 collaboration

Lars N Deutz 1 collaboration

Maxmillian D Hanlon 1 collaboration

Sashi Kant 1 collaboration

Sumitava Dastidar 1 collaboration

Vandana Agrawal 1 collaboration

Amy H Attaway 1 collaboration

Ryan Musich 1 collaboration

George R Stark 1 collaboration

Francesco Saverio Tedesco 1 collaboration

I David Weiner 1 collaboration

Sadashiva S Karnik 1 collaboration

Srinivasan Dasarathy 1 collaboration

Ge Zhang 1 collaboration

Èlia Bosch-Rué 1 collaboration

Román A Pérez 1 collaboration

Christopher G Vann 1 collaboration

Xin Zhang 1 collaboration

Melissa C Orenduff 1 collaboration

Yu-Hsiu Chen 1 collaboration

David L Corcoran 1 collaboration

Virginia B Kraus 1 collaboration

Joseph A Prinz 1 collaboration

Devjanee Swain-Lenz 1 collaboration

Neel K Prabhu 1 collaboration

Taylor Roberts 1 collaboration

Meghan Buldo 1 collaboration

Amber Detwiler 1 collaboration

Zachary D Fralish 1 collaboration

Sahar Vakili 1 collaboration

Elizabeth K Izydore 1 collaboration

Leonhard Losert 1 collaboration

Wayne A Cabral 1 collaboration

Urraca L Tavarez 1 collaboration

Huijing Xue 1 collaboration

Michael R Erdos 1 collaboration

Francis S Collins 1 collaboration