Frieder Hadlich

Affiliations

Leibniz Institute for Farm Animal Biology (FBN), Institute of Genome Biology, 18196, Dummerstorf, Germany.

Publications (35)

Development and evaluation of a milk protein transcript depletion method for differential transcriptome analysis in mammary gland tissue.

BMC genomics

Avec: Johanna Brodhagen , Rosemarie Weikard , Ulrike Thom , Annika Heimes , Juliane Günther , Frieder Hadlich , Holm Zerbe , Wolfgang Petzl , Marie M Meyerholz , Martina Hoedemaker , Hans-Joachim Schuberth , Susanne Engelmann , Christa Kühn

rePROBE: Workflow for Revised Probe Assignment and Updated Probe-set Annotation in Microarrays.

Genomics, proteomics & bioinformatics

Avec: Frieder Hadlich , Henry Reyer , Michael Oster , Nares Trakooljul , Eduard Muráni , Siriluck Ponsuksili , Klaus Wimmers

Multi-Omics Reveals Different Strategies in the Immune and Metabolic Systems of High-Yielding Strains of Laying Hens.

Frontiers in genetics

Avec: Muhammad Arsalan Iqbal , Henry Reyer , Michael Oster , Frieder Hadlich , Nares Trakooljul , Alvaro Perdomo-Sabogal , Sonja Schmucker , Volker Stefanski , Christoph Roth , Amélia Camarinha Silva , Korinna Huber , Vera Sommerfeld , Markus Rodehutscord , Klaus Wimmers , Siriluck Ponsuksili

Innovative construction of the first reliable catalogue of bovine circular RNAs.

RNA biology

Avec: Annie Robic , Frieder Hadlich , Gabriel Costa Monteiro Moreira , Emily Louise Clark , Graham Plastow , Carole Charlier , Christa Kühn

eQTL-Detect: nextflow-based pipeline for eQTL detection in modular format with sharable and parallelizable scripts.

NAR genomics and bioinformatics

Avec: Praveen Krishna Chitneedi , Frieder Hadlich , Gabriel C M Moreira , Jose Espinosa-Carrasco , Changxi Li , Graham Plastow , Daniel Fischer , Carole Charlier , Dominique Rocha , Amanda J Chamberlain , Christa Kuehn

Transcriptome Responses to Dexamethasone Depending on Dose and Glucocorticoid Receptor Sensitivity in the Liver.

Frontiers in genetics

Avec: Eduard Murani , Nares Trakooljul , Frieder Hadlich , Siriluck Ponsuksili , Klaus Wimmers

Brain Transcriptome Responses to Dexamethasone Depending on Dose and Sex Reveal Factors Contributing to Sex-Specific Vulnerability to Stress-Induced Disorders.

Neuroendocrinology

Avec: Eduard Murani , Nares Trakooljul , Frieder Hadlich , Siriluck Ponsuksili , Klaus Wimmers

Erratum: Ali et al. In Utero Fetal Weight in Pigs Is Regulated by microRNAs and Their Target Genes.

Genes

Avec: Asghar Ali , Eduard Murani , Frieder Hadlich , Xuan Liu , Klaus Wimmers , Siriluck Ponsuksili

Dietary phosphorus and calcium in feed affects miRNA profiles and their mRNA targets in jejunum of two strains of laying hens.

Scientific reports

Avec: Muhammad Arsalan Iqbal , Asghar Ali , Frieder Hadlich , Michael Oster , Henry Reyer , Nares Trakooljul , Vera Sommerfeld , Markus Rodehutscord , Klaus Wimmers , Siriluck Ponsuksili

The dynamics of molecular, immune and physiological features of the host and the gut microbiome, and their interactions before and after onset of laying in two hen strains.

Poultry science

Avec: Siriluck Ponsuksili , Frieder Hadlich , Alvaro Perdomo-Sabogal , Henry Reyer , Michael Oster , Nares Trakooljul , Muhammad Arsalan Iqbal , Sonja Schmucker , Volker Stefanski , Christoph Roth , Amélia Camarinha Silva , Korinna Huber , Vera Sommerfeld , Markus Rodehutscord , Klaus Wimmers

Glucocorticoid receptor hypersensitivity enhances inflammatory signaling and inhibits cell cycle progression in porcine PBMCs.

Frontiers in immunology

Avec: Zhiwei Li , Frieder Hadlich , Klaus Wimmers , Eduard Murani

Exploration of genotype-by-environment interactions affecting gene expression responses in porcine immune cells.

Frontiers in genetics

Avec: Eduard Murani , Frieder Hadlich

Prenatal Skeletal Muscle Transcriptome Analysis Reveals Novel MicroRNA-mRNA Networks Associated with Intrauterine Growth Restriction in Pigs.

Cells

Avec: Asghar Ali , Eduard Murani , Frieder Hadlich , Xuan Liu , Klaus Wimmers , Siriluck Ponsuksili

Genetic Regulation of Liver Metabolites and Transcripts Linking to Biochemical-Clinical Parameters.

Frontiers in genetics

Avec: Siriluck Ponsuksili , Nares Trakooljul , Frieder Hadlich , Karen Methling , Michael Lalk , Eduard Murani , Klaus Wimmers

Comparative Analysis of the Transcriptome and Distribution of Putative SNPs in Two Rainbow Trout (

Genes

Avec: Lidia de Los Ríos-Pérez , Ronald Marco Brunner , Frieder Hadlich , Alexander Rebl , Carsten Kühn , Dörte Wittenburg , Tom Goldammer , Marieke Verleih

Single-cell RNA sequencing of freshly isolated bovine milk cells and cultured primary mammary epithelial cells.

Scientific data

Avec: Doreen Becker , Rosemarie Weikard , Frieder Hadlich , Christa Kühn

Genetic regulation and heritability of miRNA and mRNA expression link to phosphorus utilization and gut microbiome.

Open biology

Avec: Siriluck Ponsuksili , Michael Oster , Henry Reyer , Frieder Hadlich , Nares Trakooljul , Markus Rodehutscord , Amélia Camarinha-Silva , Jörn Bennewitz , Klaus Wimmers

Genetic regulation and variation of expression of miRNA and mRNA transcripts in fetal muscle tissue in the context of sex, dam and variable fetal weight.

Biology of sex differences

Avec: Siriluck Ponsuksili , Eduard Murani , Frieder Hadlich , Alvaro Perdomo-Sabogal , Nares Trakooljul , Michael Oster , Henry Reyer , Klaus Wimmers

SNP discovery and association study for growth, fatness and meat quality traits in Iberian crossbred pigs.

Scientific reports

Avec: C Óvilo , N Trakooljul , Y Núñez , F Hadlich , E Murani , M Ayuso , C García-Contreras , M Vázquez-Gómez , A I Rey , F Garcia , J M García-Casco , C López-Bote , B Isabel , A González-Bulnes , K Wimmers , M Muñoz

Transcriptomic Response of Differentiating Porcine Myotubes to Thermal Stress and Donor Piglet Age.

International journal of molecular sciences

Avec: Fabio Sarais , Katharina Metzger , Frieder Hadlich , Claudia Kalbe , Siriluck Ponsuksili

Identification of the Key Molecular Drivers of Phosphorus Utilization Based on Host miRNA-mRNA and Gut Microbiome Interactions.

International journal of molecular sciences

Avec: Siriluck Ponsuksili , Henry Reyer , Frieder Hadlich , Frank Weber , Nares Trakooljul , Michael Oster , Puntita Siengdee , Eduard Muráni , Markus Rodehutscord , Amélia Camarinha-Silva , Jörn Bennewitz , Klaus Wimmers

The First Highly Contiguous Genome Assembly of Pikeperch (

Genes

Avec: Julien Alban Nguinkal , Ronald Marco Brunner , Marieke Verleih , Alexander Rebl , Lidia de Los Ríos-Pérez , Nadine Schäfer , Frieder Hadlich , Marcus Stüeken , Dörte Wittenburg , Tom Goldammer

Deep sequencing of small non-coding RNA highlights brain-specific expression patterns and RNA cleavage.

RNA biology

Avec: Fiete Haack , Nares Trakooljul , Kevin Gley , Eduard Murani , Frieder Hadlich , Klaus Wimmers , Siriluck Ponsuksili

Epigenome-wide skeletal muscle DNA methylation profiles at the background of distinct metabolic types and ryanodine receptor variation in pigs.

BMC genomics

Avec: Siriluck Ponsuksili , Nares Trakooljul , Sajjanar Basavaraj , Frieder Hadlich , Eduard Murani , Klaus Wimmers

MicroRNA-mRNA Networks in Pregnancy Complications: A Comprehensive Downstream Analysis of Potential Biomarkers.

International journal of molecular sciences

Avec: Asghar Ali , Frieder Hadlich , Muhammad W Abbas , Muhammad A Iqbal , Dawit Tesfaye , Gerrit J Bouma , Quinton A Winger , Siriluck Ponsuksili

Transcriptome analysis of porcine PBMCs reveals lipopolysaccharide-induced immunomodulatory responses and crosstalk of immune and glucocorticoid receptor signaling.

Virulence

Avec: Zhiwei Li , Nares Trakooljul , Frieder Hadlich , Siriluck Ponsuksili , Klaus Wimmers , Eduard Murani

In Utero Fetal Weight in Pigs Is Regulated by microRNAs and Their Target Genes.

Genes

Avec: Asghar Ali , Eduard Murani , Frieder Hadlich , Xuan Liu , Klaus Wimmers , Siriluck Ponsuksili

Prenatal transcript levels and metabolomics analyses reveal metabolic changes associated with intrauterine growth restriction and sex.

Open biology

Avec: Siriluck Ponsuksili , Eduard Murani , Frieder Hadlich , Muhammad Arsalan Iqbal , Beate Fuchs , Christina E Galuska , Alvaro Perdomo-Sabogal , Fabio Sarais , Nares Trakooljul , Henry Reyer , Michael Oster , Klaus Wimmers

RNA-Seq-based discovery of genetic variants and allele-specific expression of two layer lines and broiler chicken.

Evolutionary applications

Avec: Muhammad Arsalan Iqbal , Frieder Hadlich , Henry Reyer , Michael Oster , Nares Trakooljul , Eduard Murani , Alvaro Perdomo-Sabogal , Klaus Wimmers , Siriluck Ponsuksili

Genetic background and production periods shape the microRNA profiles of the gut in laying hens.

Genomics

Avec: Siriluck Ponsuksili , Frieder Hadlich , Henry Reyer , Michael Oster , Nares Trakooljul , Muhammad A Iqbal , Vera Sommerfeld , Markus Rodehutscord , Klaus Wimmers

Multi-Transcript Level Profiling Revealed Distinct mRNA, miRNA, and tRNA-Derived Fragment Bio-Signatures for Coping Behavior Linked Haplotypes in HPA Axis and Limbic System.

Frontiers in genetics

Avec: Kevin Gley , Frieder Hadlich , Nares Trakooljul , Fiete Haack , Eduard Murani , Ulrike Gimsa , Klaus Wimmers , Siriluck Ponsuksili

DNA methylation landscapes from pig's limbic structures underline regulatory mechanisms relevant for brain plasticity.

Scientific reports

Avec: Alvaro Perdomo-Sabogal , Nares Trakooljul , Frieder Hadlich , Eduard Murani , Klaus Wimmers , Siriluck Ponsuksili

Inhibition of KRAS, MEK and PI3K Demonstrate Synergistic Anti-Tumor Effects in Pancreatic Ductal Adenocarcinoma Cell Lines.

Cancers

Avec: Yixuan Ma , Benjamin Schulz , Nares Trakooljul , Moosheer Al Ammar , Anett Sekora , Sina Sender , Frieder Hadlich , Dietmar Zechner , Frank Ulrich Weiss , Markus M Lerch , Robert Jaster , Christian Junghanss , Hugo Murua Escobar

Allele-biased expression of the bovine APOB gene associated with the cholesterol deficiency defect suggests cis-regulatory enhancer effects of the LTR retrotransposon insertion.

Scientific reports

Avec: Doreen Becker , Rosemarie Weikard , Annika Heimes , Frieder Hadlich , Harald M Hammon , Marie M Meyerholz , Wolfram Petzl , Holm Zerbe , Hans-Joachim Schuberth , Martina Hoedemaker , Marion Schmicke , Susanne Engelmann , Christa Kühn

Dynamics of DNA methylation during osteogenic differentiation of porcine synovial membrane mesenchymal stem cells from two metabolically distinct breeds.

Epigenetics

Avec: Shuaichen Li , Puntita Siengdee , Frieder Hadlich , Nares Trakooljul , Michael Oster , Henry Reyer , Klaus Wimmers , Siriluck Ponsuksili

Réseau de co-auteurs

Siriluck Ponsuksili 24 collaborations

Klaus Wimmers 23 collaborations

Nares Trakooljul 20 collaborations

Eduard Murani 16 collaborations

Henry Reyer 11 collaborations

Michael Oster 11 collaborations

Alvaro Perdomo-Sabogal 6 collaborations

Markus Rodehutscord 6 collaborations

Muhammad Arsalan Iqbal 5 collaborations

Asghar Ali 5 collaborations

Christa Kühn 4 collaborations

Vera Sommerfeld 4 collaborations

Rosemarie Weikard 3 collaborations

Xuan Liu 3 collaborations

Annika Heimes 2 collaborations

Holm Zerbe 2 collaborations

Marie M Meyerholz 2 collaborations

Martina Hoedemaker 2 collaborations

Hans-Joachim Schuberth 2 collaborations

Susanne Engelmann 2 collaborations

Eduard Muráni 2 collaborations

Sonja Schmucker 2 collaborations

Volker Stefanski 2 collaborations

Christoph Roth 2 collaborations

Amélia Camarinha Silva 2 collaborations

Korinna Huber 2 collaborations

Graham Plastow 2 collaborations

Carole Charlier 2 collaborations

Zhiwei Li 2 collaborations

Lidia de Los Ríos-Pérez 2 collaborations

Ronald Marco Brunner 2 collaborations

Alexander Rebl 2 collaborations

Dörte Wittenburg 2 collaborations

Tom Goldammer 2 collaborations

Marieke Verleih 2 collaborations

Doreen Becker 2 collaborations

Amélia Camarinha-Silva 2 collaborations

Jörn Bennewitz 2 collaborations

Fabio Sarais 2 collaborations

Puntita Siengdee 2 collaborations

Fiete Haack 2 collaborations

Kevin Gley 2 collaborations

Muhammad A Iqbal 2 collaborations

Johanna Brodhagen 1 collaboration

Ulrike Thom 1 collaboration

Juliane Günther 1 collaboration

Wolfgang Petzl 1 collaboration

Annie Robic 1 collaboration

Gabriel Costa Monteiro Moreira 1 collaboration

Emily Louise Clark 1 collaboration

Praveen Krishna Chitneedi 1 collaboration

Gabriel C M Moreira 1 collaboration

Jose Espinosa-Carrasco 1 collaboration

Changxi Li 1 collaboration

Daniel Fischer 1 collaboration

Dominique Rocha 1 collaboration

Amanda J Chamberlain 1 collaboration

Christa Kuehn 1 collaboration

Karen Methling 1 collaboration

Michael Lalk 1 collaboration

Carsten Kühn 1 collaboration

C Óvilo 1 collaboration

N Trakooljul 1 collaboration

Y Núñez 1 collaboration

F Hadlich 1 collaboration

E Murani 1 collaboration

M Ayuso 1 collaboration

C García-Contreras 1 collaboration

M Vázquez-Gómez 1 collaboration

A I Rey 1 collaboration

F Garcia 1 collaboration

J M García-Casco 1 collaboration

C López-Bote 1 collaboration

B Isabel 1 collaboration

A González-Bulnes 1 collaboration

K Wimmers 1 collaboration

M Muñoz 1 collaboration

Katharina Metzger 1 collaboration

Claudia Kalbe 1 collaboration

Frank Weber 1 collaboration

Julien Alban Nguinkal 1 collaboration

Nadine Schäfer 1 collaboration

Marcus Stüeken 1 collaboration

Sajjanar Basavaraj 1 collaboration

Muhammad W Abbas 1 collaboration

Dawit Tesfaye 1 collaboration

Gerrit J Bouma 1 collaboration

Quinton A Winger 1 collaboration

Beate Fuchs 1 collaboration

Christina E Galuska 1 collaboration

Ulrike Gimsa 1 collaboration

Yixuan Ma 1 collaboration

Benjamin Schulz 1 collaboration

Moosheer Al Ammar 1 collaboration

Anett Sekora 1 collaboration

Sina Sender 1 collaboration

Dietmar Zechner 1 collaboration

Frank Ulrich Weiss 1 collaboration

Markus M Lerch 1 collaboration

Robert Jaster 1 collaboration

Christian Junghanss 1 collaboration

Hugo Murua Escobar 1 collaboration

Harald M Hammon 1 collaboration

Wolfram Petzl 1 collaboration

Marion Schmicke 1 collaboration

Shuaichen Li 1 collaboration