Florent Chuffart

Affiliations

CNRS UMR 5309/INSERM U1209/Université Grenoble-Alpes/Institute for Advanced Biosciences, 38706 La Tronche, France; Pôle Franco-Chinois de Recherche en Sciences du Vivant et Génomique, 200025 Shanghai, China.

Publications (21)

Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution.

Cell reports

Avec: Mengqing Gao , Jin Wang , Sophie Rousseaux , Minjia Tan , Lulu Pan , Lijun Peng , Sisi Wang , Wenqian Xu , Jiayi Ren , Yuanfang Liu , Martin Spinck , Sophie Barral , Tao Wang , Florent Chuffart , Ekaterina Bourova-Flin , Denis Puthier , Sandrine Curtet , Lisa Bargier , Zhongyi Cheng , Heinz Neumann , Jian Li , Yingming Zhao , Jian-Qing Mi , Saadi Khochbin

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

Cancer discovery

Avec: Valentina Lukinović , Simone Hausmann , Gael S Roth , Clement Oyeniran , Tanveer Ahmad , Ning Tsao , Joshua R Brickner , Alexandre G Casanova , Florent Chuffart , Ana Morales Benitez , Jessica Vayr , Rebecca Rodell , Marianne Tardif , Pascal W T C Jansen , Yohann Couté , Michiel Vermeulen , Pierre Hainaut , Pawel K Mazur , Nima Mosammaparast , Nicolas Reynoird

Histone variants: critical determinants in tumour heterogeneity.

Frontiers of medicine

Avec: Tao Wang , Florent Chuffart , Ekaterina Bourova-Flin , Jin Wang , Jianqing Mi , Sophie Rousseaux , Saadi Khochbin

CCM2-deficient endothelial cells undergo a ROCK-dependent reprogramming into senescence-associated secretory phenotype.

Angiogenesis

Avec: Daphné Raphaëlle Vannier , Apeksha Shapeti , Florent Chuffart , Emmanuelle Planus , Sandra Manet , Paul Rivier , Olivier Destaing , Corinne Albiges-Rizo , Hans Van Oosterwyck , Eva Faurobert

Aberrant activation of five embryonic stem cell-specific genes robustly predicts a high risk of relapse in breast cancers.

BMC genomics

Avec: Emmanuelle Jacquet , Florent Chuffart , Anne-Laure Vitte , Eleni Nika , Mireille Mousseau , Saadi Khochbin , Sophie Rousseaux , Ekaterina Bourova-Flin

Immediate and durable effects of maternal tobacco consumption alter placental DNA methylation in enhancer and imprinted gene-containing regions.

BMC medicine

Avec: Sophie Rousseaux , Emie Seyve , Florent Chuffart , Ekaterina Bourova-Flin , Meriem Benmerad , Marie-Aline Charles , Anne Forhan , Barbara Heude , Valérie Siroux , Remy Slama , Jorg Tost , Daniel Vaiman , Saadi Khochbin , Johanna Lepeule , Auteur inconnu

DEN-Induced Rat Model Reproduces Key Features of Human Hepatocellular Carcinoma.

Cancers

Avec: Keerthi Kurma , Olivier Manches , Florent Chuffart , Nathalie Sturm , Khaldoun Gharzeddine , Jianhui Zhang , Marion Mercey-Ressejac , Sophie Rousseaux , Arnaud Millet , Herve Lerat , Patrice N Marche , Zuzana Macek Jilkova , Thomas Decaens

AKR1B10, One of the Triggers of Cytokine Storm in SARS-CoV2 Severe Acute Respiratory Syndrome.

International journal of molecular sciences

Avec: Clovis Chabert , Anne-Laure Vitte , Domenico Iuso , Florent Chuffart , Candice Trocme , Marlyse Buisson , Pascal Poignard , Benjamin Lardinois , Régis Debois , Sophie Rousseaux , Jean-Louis Pepin , Jean-Benoit Martinot , Saadi Khochbin

Luspatercept (RAP-536) modulates oxidative stress without affecting mutation burden in myelodysplastic syndromes.

Annals of hematology

Avec: Meunier Mathieu , Chloé Friedrich , Nicolas Ducrot , Johanna Zannoni , Tondeur Sylvie , Nelly Jerraya , Sophie Rousseaux , Florent Chuffart , Olivier Kosmider , Zoubida Karim , Sophie Park

Long-term intermittent hypoxia in mice induces inflammatory pathways implicated in sleep apnea and steatohepatitis in humans.

iScience

Avec: Jonathan Gaucher , Emilie Montellier , Guillaume Vial , Florent Chuffart , Maëlle Guellerin , Sophie Bouyon , Emeline Lemarie , Yoshiki Yamaryo Botté , Aya Dirani , Raoua Ben Messaoud , Marie Joyeux Faure , Diane Godin Ribuot , Charlotte Costentin , Renaud Tamisier , Cyrille Y Botté , Saadi Khochbin , Sophie Rousseaux , Jean-Louis Pépin

ATAD2 controls chromatin-bound HIRA turnover.

Life science alliance

Avec: Tao Wang , Daniel Perazza , Fayçal Boussouar , Matteo Cattaneo , Alexandre Bougdour , Florent Chuffart , Sophie Barral , Alexandra Vargas , Ariadni Liakopoulou , Denis Puthier , Lisa Bargier , Yuichi Morozumi , Mahya Jamshidikia , Isabel Garcia-Saez , Carlo Petosa , Sophie Rousseaux , André Verdel , Saadi Khochbin

Chidamide inhibits the NOTCH1-MYC signaling axis in T-cell acute lymphoblastic leukemia.

Frontiers of medicine

Avec: Mengping Xi , Shanshan Guo , Caicike Bayin , Lijun Peng , Florent Chuffart , Ekaterina Bourova-Flin , Sophie Rousseaux , Saadi Khochbin , Jian-Qing Mi , Jin Wang

Direct visualization of pre-protamine 2 detects protamine assembly failures and predicts ICSI success.

Molecular human reproduction

Avec: Maryam Rezaei-Gazik , Alexandra Vargas , Amir Amiri-Yekta , Anne-Laure Vitte , Arvand Akbari , Sophie Barral , Vahid Esmaeili , Florent Chuffart , Mohammad Ali Sadighi-Gilani , Yohann Couté , Poopak Eftekhari-Yazdi , Saadi Khochbin , Sophie Rousseaux , Mehdi Totonchi

Ectopic expression of a combination of 5 genes detects high risk forms of T-cell acute lymphoblastic leukemia.

BMC genomics

Avec: Li-Jun Peng , Yue-Bo Zhou , Mei Geng , Ekaterina Bourova-Flin , Florent Chuffart , Wei-Na Zhang , Tao Wang , Meng-Qing Gao , Meng-Ping Xi , Zhong-Yi Cheng , Jiao-Jiao Zhang , Yuan-Fang Liu , Bing Chen , Saadi Khochbin , Jin Wang , Sophie Rousseaux , Jian-Qing Mi

Chronic Intermittent Hypoxia Increases Cell Proliferation in Hepatocellular Carcinoma.

Cells

Avec: Lydie Carreres , Marion Mercey-Ressejac , Keerthi Kurma , Julien Ghelfi , Carole Fournier , Olivier Manches , Florent Chuffart , Sophie Rousseaux , Mélanie Minoves , Thomas Decaens , Herve Lerat , Zuzana Macek Jilkova

PenDA, a rank-based method for personalized differential analysis: Application to lung cancer.

PLoS computational biology

Avec: Magali Richard , Clémentine Decamps , Florent Chuffart , Elisabeth Brambilla , Sophie Rousseaux , Saadi Khochbin , Daniel Jost

Lysine Methyltransferases Signaling: Histones are Just the Tip of the Iceberg.

Current protein & peptide science

Avec: Valentina Lukinović , Alexandre G Casanova , Gael S Roth , Florent Chuffart , Nicolas Reynoird

RNA-Guided Genomic Localization of H2A.L.2 Histone Variant.

Cells

Avec: Naghmeh Hoghoughi , Sophie Barral , Sandrine Curtet , Florent Chuffart , Guillaume Charbonnier , Denis Puthier , Thierry Buchou , Sophie Rousseaux , Saadi Khochbin

The combined detection of Amphiregulin, Cyclin A1 and DDX20/Gemin3 expression predicts aggressive forms of oral squamous cell carcinoma.

British journal of cancer

Avec: Ekaterina Bourova-Flin , Samira Derakhshan , Afsaneh Goudarzi , Tao Wang , Anne-Laure Vitte , Florent Chuffart , Saadi Khochbin , Sophie Rousseaux , Pouyan Aminishakib

Chromatin-associated YTHDC1 coordinates heat-induced reprogramming of gene expression.

Cell reports

Avec: Kalina Timcheva , Solenne Dufour , Leila Touat-Todeschini , Callum Burnard , Marie-Christine Carpentier , Florent Chuffart , Rémy Merret , Marion Helsmoortel , Sabrina Ferré , Aude Grézy , Yohann Couté , Sophie Rousseaux , Saadi Khochbin , Claire Vourc'h , Cécile Bousquet-Antonelli , Rosemary Kiernan , Daphné Seigneurin-Berny , André Verdel

Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet.

Science advances

Avec: Domenico Iuso , Isabel Garcia-Saez , Yohann Couté , Yoshiki Yamaryo-Botté , Elisabetta Boeri Erba , Annie Adrait , Nour Zeaiter , Malgorzata Tokarska-Schlattner , Zuzana Macek Jilkova , Fayçal Boussouar , Sophie Barral , Luca Signor , Karine Couturier , Azadeh Hajmirza , Florent Chuffart , Ekaterina Bourova-Flin , Anne-Laure Vitte , Lisa Bargier , Denis Puthier , Thomas Decaens , Sophie Rousseaux , Cyrille Botté , Uwe Schlattner , Carlo Petosa , Saadi Khochbin

Réseau de co-auteurs

Sophie Rousseaux 18 collaborations

Saadi Khochbin 15 collaborations

Ekaterina Bourova-Flin 8 collaborations

Sophie Barral 5 collaborations

Tao Wang 5 collaborations

Anne-Laure Vitte 5 collaborations

Jin Wang 4 collaborations

Denis Puthier 4 collaborations

Yohann Couté 4 collaborations

Lisa Bargier 3 collaborations

Jian-Qing Mi 3 collaborations

Zuzana Macek Jilkova 3 collaborations

Thomas Decaens 3 collaborations

Lijun Peng 2 collaborations

Sandrine Curtet 2 collaborations

Valentina Lukinović 2 collaborations

Gael S Roth 2 collaborations

Alexandre G Casanova 2 collaborations

Nicolas Reynoird 2 collaborations

Keerthi Kurma 2 collaborations

Olivier Manches 2 collaborations

Marion Mercey-Ressejac 2 collaborations

Herve Lerat 2 collaborations

Domenico Iuso 2 collaborations

Fayçal Boussouar 2 collaborations

Alexandra Vargas 2 collaborations

Isabel Garcia-Saez 2 collaborations

Carlo Petosa 2 collaborations

André Verdel 2 collaborations

Mengqing Gao 1 collaboration

Minjia Tan 1 collaboration

Lulu Pan 1 collaboration

Sisi Wang 1 collaboration

Wenqian Xu 1 collaboration

Jiayi Ren 1 collaboration

Yuanfang Liu 1 collaboration

Martin Spinck 1 collaboration

Zhongyi Cheng 1 collaboration

Heinz Neumann 1 collaboration

Jian Li 1 collaboration

Yingming Zhao 1 collaboration

Simone Hausmann 1 collaboration

Clement Oyeniran 1 collaboration

Tanveer Ahmad 1 collaboration

Ning Tsao 1 collaboration

Joshua R Brickner 1 collaboration

Ana Morales Benitez 1 collaboration

Jessica Vayr 1 collaboration

Rebecca Rodell 1 collaboration

Marianne Tardif 1 collaboration

Pascal W T C Jansen 1 collaboration

Michiel Vermeulen 1 collaboration

Pierre Hainaut 1 collaboration

Pawel K Mazur 1 collaboration

Nima Mosammaparast 1 collaboration

Jianqing Mi 1 collaboration

Daphné Raphaëlle Vannier 1 collaboration

Apeksha Shapeti 1 collaboration

Emmanuelle Planus 1 collaboration

Sandra Manet 1 collaboration

Paul Rivier 1 collaboration

Olivier Destaing 1 collaboration

Corinne Albiges-Rizo 1 collaboration

Hans Van Oosterwyck 1 collaboration

Eva Faurobert 1 collaboration

Emmanuelle Jacquet 1 collaboration

Eleni Nika 1 collaboration

Mireille Mousseau 1 collaboration

Emie Seyve 1 collaboration

Meriem Benmerad 1 collaboration

Marie-Aline Charles 1 collaboration

Anne Forhan 1 collaboration

Barbara Heude 1 collaboration

Valérie Siroux 1 collaboration

Remy Slama 1 collaboration

Jorg Tost 1 collaboration

Daniel Vaiman 1 collaboration

Johanna Lepeule 1 collaboration

None None 1 collaboration

Nathalie Sturm 1 collaboration

Khaldoun Gharzeddine 1 collaboration

Jianhui Zhang 1 collaboration

Arnaud Millet 1 collaboration

Patrice N Marche 1 collaboration

Clovis Chabert 1 collaboration

Candice Trocme 1 collaboration

Marlyse Buisson 1 collaboration

Pascal Poignard 1 collaboration

Benjamin Lardinois 1 collaboration

Régis Debois 1 collaboration

Jean-Louis Pepin 1 collaboration

Jean-Benoit Martinot 1 collaboration

Meunier Mathieu 1 collaboration

Chloé Friedrich 1 collaboration

Nicolas Ducrot 1 collaboration

Johanna Zannoni 1 collaboration

Tondeur Sylvie 1 collaboration

Nelly Jerraya 1 collaboration

Olivier Kosmider 1 collaboration

Zoubida Karim 1 collaboration

Sophie Park 1 collaboration

Jonathan Gaucher 1 collaboration

Emilie Montellier 1 collaboration

Guillaume Vial 1 collaboration

Maëlle Guellerin 1 collaboration

Sophie Bouyon 1 collaboration

Emeline Lemarie 1 collaboration

Yoshiki Yamaryo Botté 1 collaboration

Aya Dirani 1 collaboration

Raoua Ben Messaoud 1 collaboration

Marie Joyeux Faure 1 collaboration

Diane Godin Ribuot 1 collaboration

Charlotte Costentin 1 collaboration

Renaud Tamisier 1 collaboration

Cyrille Y Botté 1 collaboration

Jean-Louis Pépin 1 collaboration

Daniel Perazza 1 collaboration

Matteo Cattaneo 1 collaboration

Alexandre Bougdour 1 collaboration

Ariadni Liakopoulou 1 collaboration

Yuichi Morozumi 1 collaboration

Mahya Jamshidikia 1 collaboration

Mengping Xi 1 collaboration

Shanshan Guo 1 collaboration

Caicike Bayin 1 collaboration

Maryam Rezaei-Gazik 1 collaboration

Amir Amiri-Yekta 1 collaboration

Arvand Akbari 1 collaboration

Vahid Esmaeili 1 collaboration

Mohammad Ali Sadighi-Gilani 1 collaboration

Poopak Eftekhari-Yazdi 1 collaboration

Mehdi Totonchi 1 collaboration

Li-Jun Peng 1 collaboration

Yue-Bo Zhou 1 collaboration

Mei Geng 1 collaboration

Wei-Na Zhang 1 collaboration

Meng-Qing Gao 1 collaboration

Meng-Ping Xi 1 collaboration

Zhong-Yi Cheng 1 collaboration

Jiao-Jiao Zhang 1 collaboration

Yuan-Fang Liu 1 collaboration

Bing Chen 1 collaboration

Lydie Carreres 1 collaboration

Julien Ghelfi 1 collaboration

Carole Fournier 1 collaboration

Mélanie Minoves 1 collaboration

Magali Richard 1 collaboration

Clémentine Decamps 1 collaboration

Elisabeth Brambilla 1 collaboration

Daniel Jost 1 collaboration

Naghmeh Hoghoughi 1 collaboration

Guillaume Charbonnier 1 collaboration

Thierry Buchou 1 collaboration

Samira Derakhshan 1 collaboration

Afsaneh Goudarzi 1 collaboration

Pouyan Aminishakib 1 collaboration

Kalina Timcheva 1 collaboration

Solenne Dufour 1 collaboration

Leila Touat-Todeschini 1 collaboration

Callum Burnard 1 collaboration

Marie-Christine Carpentier 1 collaboration

Rémy Merret 1 collaboration

Marion Helsmoortel 1 collaboration

Sabrina Ferré 1 collaboration

Aude Grézy 1 collaboration

Claire Vourc'h 1 collaboration

Cécile Bousquet-Antonelli 1 collaboration

Rosemary Kiernan 1 collaboration

Daphné Seigneurin-Berny 1 collaboration

Yoshiki Yamaryo-Botté 1 collaboration

Elisabetta Boeri Erba 1 collaboration

Annie Adrait 1 collaboration

Nour Zeaiter 1 collaboration

Malgorzata Tokarska-Schlattner 1 collaboration

Luca Signor 1 collaboration

Karine Couturier 1 collaboration

Azadeh Hajmirza 1 collaboration

Cyrille Botté 1 collaboration

Uwe Schlattner 1 collaboration