Erik A A Wallén

Affiliations

Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, P.O. Box 56, FI- 00014 Helsinki, Finland.

Publications (8)

A scaffold replacement approach towards new sirtuin 2 inhibitors.

Bioorganic & medicinal chemistry

Avec: Tina Seifert , Marcus Malo , Tarja Kokkola , E Johanna L Stéen , Kristian Meinander , Erik A A Wallén , Elina M Jarho , Kristina Luthman

Tetrazole as a Replacement of the Electrophilic Group in Characteristic Prolyl Oligopeptidase Inhibitors.

ACS medicinal chemistry letters

Avec: Tommi P Kilpeläinen , Jonna K Tyni , Maija K Lahtela-Kakkonen , Tony S Eteläinen , Timo T Myöhänen , Erik A A Wallén

2-Imidazole as a Substitute for the Electrophilic Group Gives Highly Potent Prolyl Oligopeptidase Inhibitors.

ACS medicinal chemistry letters

Avec: Henri T Pätsi , Tommi P Kilpeläinen , Samuli Auno , Pyry M J Dillemuth , Khaled Arja , Maija K Lahtela-Kakkonen , Timo T Myöhänen , Erik A A Wallén

Nonpeptidic Oxazole-Based Prolyl Oligopeptidase Ligands with Disease-Modifying Effects on α-Synuclein Mouse Models of Parkinson's Disease.

Journal of medicinal chemistry

Avec: Tommi P Kilpeläinen , Henri T Pätsi , Reinis Svarcbahs , Ulrika H Julku , Tony S Eteläinen , Hengjing Cui , Samuli Auno , Nina Sipari , Susanna Norrbacka , Teppo O Leino , Maria Jäntti , Timo T Myöhänen , Erik A A Wallén

Structure-Activity Relationships of 1-Benzoylazulenes at the OX

ChemMedChem

Avec: Ainoleena Turku , Teppo O Leino , Lasse Karhu , Jari Yli-Kauhaluoma , Jyrki P Kukkonen , Erik A A Wallén , Henri Xhaard

The azulene scaffold from a medicinal chemist's perspective: Physicochemical and in vitro parameters relevant for drug discovery.

European journal of medicinal chemistry

Avec: Teppo O Leino , Peter Sieger , Jari Yli-Kauhaluoma , Erik A A Wallén , Jörg T Kley

Azulene as a biphenyl mimetic in orexin/hypocretin receptor agonists.

Bioorganic & medicinal chemistry

Avec: Teppo O Leino , Ainoleena Turku , Lauri Urvas , Karuna Adhikari , Jouni Oksanen , Yana Steynen , Jari Yli-Kauhaluoma , Henri Xhaard , Jyrki P Kukkonen , Erik A A Wallén

5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein-Protein Interaction-Derived Functions.

Journal of medicinal chemistry

Avec: Henri T Pätsi , Tommi P Kilpeläinen , Mikael Jumppanen , Johanna Uhari-Väänänen , Pieter Van Wielendaele , Francesca De Lorenzo , Hengjing Cui , Samuli Auno , Janne Saharinen , Erin Seppälä , Nina Sipari , Juha Savinainen , Ingrid De Meester , Anne-Marie Lambeir , Maija Lahtela-Kakkonen , Timo T Myöhänen , Erik A A Wallén

Réseau de co-auteurs

Tommi P Kilpeläinen 4 collaborations

Timo T Myöhänen 4 collaborations

Teppo O Leino 4 collaborations

Henri T Pätsi 3 collaborations

Samuli Auno 3 collaborations

Jari Yli-Kauhaluoma 3 collaborations

Maija K Lahtela-Kakkonen 2 collaborations

Tony S Eteläinen 2 collaborations

Hengjing Cui 2 collaborations

Nina Sipari 2 collaborations

Ainoleena Turku 2 collaborations

Jyrki P Kukkonen 2 collaborations

Henri Xhaard 2 collaborations

Tina Seifert 1 collaboration

Marcus Malo 1 collaboration

Tarja Kokkola 1 collaboration

E Johanna L Stéen 1 collaboration

Kristian Meinander 1 collaboration

Elina M Jarho 1 collaboration

Kristina Luthman 1 collaboration

Jonna K Tyni 1 collaboration

Pyry M J Dillemuth 1 collaboration

Khaled Arja 1 collaboration

Reinis Svarcbahs 1 collaboration

Ulrika H Julku 1 collaboration

Susanna Norrbacka 1 collaboration

Maria Jäntti 1 collaboration

Lasse Karhu 1 collaboration

Peter Sieger 1 collaboration

Jörg T Kley 1 collaboration

Lauri Urvas 1 collaboration

Karuna Adhikari 1 collaboration

Jouni Oksanen 1 collaboration

Yana Steynen 1 collaboration

Mikael Jumppanen 1 collaboration

Johanna Uhari-Väänänen 1 collaboration

Pieter Van Wielendaele 1 collaboration

Francesca De Lorenzo 1 collaboration

Janne Saharinen 1 collaboration

Erin Seppälä 1 collaboration

Juha Savinainen 1 collaboration

Ingrid De Meester 1 collaboration

Anne-Marie Lambeir 1 collaboration

Maija Lahtela-Kakkonen 1 collaboration