Anne-Marie Lambeir

Affiliations

Laboratory of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium.

ORCID: https://orcid.org/0000-0001-9386-3777

Publications (21)

Selective inhibition of carboxypeptidase U may reduce microvascular thrombosis in rat experimental stroke.

Journal of thrombosis and haemostasis : JTH

Avec: Joachim C Mertens , William Boisseau , Dorien Leenaerts , Lucas Di Meglio , Stéphane Loyau , Anne-Marie Lambeir , Célina Ducroux , Martine Jandrot-Perrus , Jean-Baptiste Michel , Mikael Mazighi , Dirk Hendriks , Jean-Philippe Desilles

Study of the Conformational Dynamics of Prolyl Oligopeptidase by Mass Spectrometry: Lessons Learned.

Journal of medicinal chemistry

Avec: Roos Van Elzen , Anne-Marie Lambeir

Metal ions shape α-synuclein.

Scientific reports

Avec: Rani Moons , Albert Konijnenberg , Carl Mensch , Roos Van Elzen , Christian Johannessen , Stuart Maudsley , Anne-Marie Lambeir , Frank Sobott

Chemically diverse activity-based probes with unexpected inhibitory mechanisms targeting trypsin-like serine proteases.

Frontiers in chemistry

Avec: Alba Ramos-Llorca , Lisse Decraecker , Valérie M Y Cacheux , Irena Zeiburlina , Michelle De Bruyn , Louise Battut , Carlos Moreno-Cinos , Davide Ceradini , Eric Espinosa , Gilles Dietrich , Maya Berg , Ingrid De Meester , Pieter Van Der Veken , Guy Boeckxstaens , Anne-Marie Lambeir , Alexandre Denadai-Souza , Koen Augustyns

Proteolytic Cleavage of Bioactive Peptides and Protease-Activated Receptors in Acute and Post-Colitis.

International journal of molecular sciences

Avec: Michelle De Bruyn , Hannah Ceuleers , Nikita Hanning , Maya Berg , Joris G De Man , Paco Hulpiau , Cedric Hermans , Ulf-Håkan Stenman , Hannu Koistinen , Anne-Marie Lambeir , Benedicte Y De Winter , Ingrid De Meester

The C-terminal cleavage of angiotensin II and III is mediated by prolyl carboxypeptidase in human umbilical vein and aortic endothelial cells.

Biochemical pharmacology

Avec: Emilie De Hert , An Bracke , Anne-Marie Lambeir , Pieter Van der Veken , Ingrid De Meester

Prolyl Carboxypeptidase Mediates the C-Terminal Cleavage of (Pyr)-Apelin-13 in Human Umbilical Vein and Aortic Endothelial Cells.

International journal of molecular sciences

Avec: Emilie De Hert , An Bracke , Isabel Pintelon , Eline Janssens , Anne-Marie Lambeir , Pieter Van Der Veken , Ingrid De Meester

Frontiers in chemistry

Avec: Yentl Van Rymenant , Muhammet Tanc , Roos Van Elzen , An Bracke , Olivier De Wever , Koen Augustyns , Anne-Marie Lambeir , Mark Kockx , Ingrid De Meester , Pieter Van Der Veken

Inhibition of the procarboxypeptidase U (proCPU, TAFI, proCPB2) system due to hemolysis.

Journal of thrombosis and haemostasis : JTH

Avec: Joachim C Mertens , Karen Claesen , Dorien Leenaerts , Yani Sim , Anne-Marie Lambeir , Dirk Hendriks

Spatiotemporal expression and inhibition of prolyl oligopeptidase contradict its involvement in key pathologic mechanisms of kainic acid-induced temporal lobe epilepsy in rats.

Epilepsia open

Avec: Idrish Ali , Annemie Van Eetveldt , Roos Van Elzen , Tom Kalathil Raju , Pieter Van Der Veken , Anne-Marie Lambeir , Stefanie Dedeurwaerdere

The effect of prolyl oligopeptidase inhibitors on alpha-synuclein aggregation and autophagy cannot be predicted by their inhibitory efficacy.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: Tommi P Kilpeläinen , Laura Hellinen , Johannes Vrijdag , Xu Yan , Reinis Svarcbahs , Kati-Sisko Vellonen , Anne-Marie Lambeir , Henri Huttunen , Arto Urtti , Erik A A Wallen , Timo T Myöhänen

A novel serine protease inhibitor as potential treatment for dry eye syndrome and ocular inflammation.

Scientific reports

Avec: Cedric Joossen , Adrienn Baán , Carlos Moreno-Cinos , Jurgen Joossens , Nathalie Cools , Ellen Lanckacker , Lieve Moons , Kim Lemmens , Anne-Marie Lambeir , Erik Fransen , Peter Delputte , Guy Caljon , Pieter Van Der Veken , Louis Maes , Ingrid De Meester , Filip Kiekens , Koen Augustyns , Paul Cos

Small molecule 3PO inhibits glycolysis but does not bind to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3).

FEBS letters

Avec: Besa Emini Veseli , Paola Perrotta , Pieter Van Wielendaele , Anne-Marie Lambeir , Anahita Abdali , Stefano Bellosta , Giovanni Monaco , Geert Bultynck , Wim Martinet , Guido R Y De Meyer

Dysregulated activities of proline-specific enzymes in septic shock patients (sepsis-2).

PloS one

Avec: Gwendolyn Vliegen , Kaat Kehoe , An Bracke , Emilie De Hert , Robert Verkerk , Erik Fransen , Bart 's Jongers , Esther Peters , Anne-Marie Lambeir , Samir Kumar-Singh , Peter Pickkers , Philippe G Jorens , Ingrid De Meester

Novel Small Molecule-Derived, Highly Selective Substrates for Fibroblast Activation Protein (FAP).

ACS medicinal chemistry letters

Avec: An De Decker , Gwendolyn Vliegen , Dries Van Rompaey , Anke Peeraer , An Bracke , Line Verckist , Koen Jansen , Ruth Geiss-Friedlander , Koen Augustyns , Hans De Winter , Ingrid De Meester , Anne-Marie Lambeir , Pieter Van der Veken

Efforts towards an On-Target Version of the Groebke-Blackburn-Bienaymé (GBB) Reaction for Discovery of Druglike Urokinase (uPA) Inhibitors.

Chemistry (Weinheim an der Bergstrasse, Germany)

Avec: Rafaela Gladysz , Johannes Vrijdag , Dries Van Rompaey , Anne-Marie Lambeir , Koen Augustyns , Hans De Winter , Pieter Van der Veken

DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages.

Life science alliance

Avec: Nathalia M de Vasconcelos , Gwendolyn Vliegen , Amanda Gonçalves , Emilie De Hert , Rosa Martín-Pérez , Nina Van Opdenbosch , Anvesh Jallapally , Ruth Geiss-Friedlander , Anne-Marie Lambeir , Koen Augustyns , Pieter Van Der Veken , Ingrid De Meester , Mohamed Lamkanfi

The development and validation of a combined kinetic fluorometric activity assay for fibroblast activation protein alpha and prolyl oligopeptidase in plasma.

Clinica chimica acta; international journal of clinical chemistry

Avec: An Bracke , Roos Van Elzen , Pieter Van Der Veken , Koen Augustyns , Ingrid De Meester , Anne-Marie Lambeir

Effects of Detergent on α-Synuclein Structure. A Native MS-Ion Mobility Study.

International journal of molecular sciences

Avec: Rani Moons , Renate van der Wekken-de Bruijne , Stuart Maudsley , Filip Lemière , Anne-Marie Lambeir , Frank Sobott

5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein-Protein Interaction-Derived Functions.

Journal of medicinal chemistry

Avec: Henri T Pätsi , Tommi P Kilpeläinen , Mikael Jumppanen , Johanna Uhari-Väänänen , Pieter Van Wielendaele , Francesca De Lorenzo , Hengjing Cui , Samuli Auno , Janne Saharinen , Erin Seppälä , Nina Sipari , Juha Savinainen , Ingrid De Meester , Anne-Marie Lambeir , Maija Lahtela-Kakkonen , Timo T Myöhänen , Erik A A Wallén

Development of caspase-3-selective activity-based probes for PET imaging of apoptosis.

EJNMMI radiopharmacy and chemistry

Avec: Louis Lauwerys , Lucas Beroske , Angelo Solania , Christel Vangestel , Alan Miranda , Nele Van Giel , Karuna Adhikari , Anne-Marie Lambeir , Leonie Wyffels , Dennis Wolan , Pieter Van der Veken , Filipe Elvas

Réseau de co-auteurs

Ingrid De Meester 11 collaborations

Pieter Van Der Veken 7 collaborations

Koen Augustyns 7 collaborations

An Bracke 6 collaborations

Roos Van Elzen 5 collaborations

Emilie De Hert 4 collaborations

Pieter Van der Veken 4 collaborations

Gwendolyn Vliegen 3 collaborations

Joachim C Mertens 2 collaborations

Dorien Leenaerts 2 collaborations

Dirk Hendriks 2 collaborations

Rani Moons 2 collaborations

Stuart Maudsley 2 collaborations

Frank Sobott 2 collaborations

Michelle De Bruyn 2 collaborations

Carlos Moreno-Cinos 2 collaborations

Maya Berg 2 collaborations

Tommi P Kilpeläinen 2 collaborations

Johannes Vrijdag 2 collaborations

Timo T Myöhänen 2 collaborations

Erik Fransen 2 collaborations

Pieter Van Wielendaele 2 collaborations

Dries Van Rompaey 2 collaborations

Ruth Geiss-Friedlander 2 collaborations

Hans De Winter 2 collaborations

William Boisseau 1 collaboration

Lucas Di Meglio 1 collaboration

Stéphane Loyau 1 collaboration

Célina Ducroux 1 collaboration

Martine Jandrot-Perrus 1 collaboration

Jean-Baptiste Michel 1 collaboration

Mikael Mazighi 1 collaboration

Jean-Philippe Desilles 1 collaboration

Albert Konijnenberg 1 collaboration

Carl Mensch 1 collaboration

Christian Johannessen 1 collaboration

Alba Ramos-Llorca 1 collaboration

Lisse Decraecker 1 collaboration

Valérie M Y Cacheux 1 collaboration

Irena Zeiburlina 1 collaboration

Louise Battut 1 collaboration

Davide Ceradini 1 collaboration

Eric Espinosa 1 collaboration

Gilles Dietrich 1 collaboration

Guy Boeckxstaens 1 collaboration

Alexandre Denadai-Souza 1 collaboration

Hannah Ceuleers 1 collaboration

Nikita Hanning 1 collaboration

Joris G De Man 1 collaboration

Paco Hulpiau 1 collaboration

Cedric Hermans 1 collaboration

Ulf-Håkan Stenman 1 collaboration

Hannu Koistinen 1 collaboration

Benedicte Y De Winter 1 collaboration

Isabel Pintelon 1 collaboration

Eline Janssens 1 collaboration

Yentl Van Rymenant 1 collaboration

Muhammet Tanc 1 collaboration

Olivier De Wever 1 collaboration

Mark Kockx 1 collaboration

Karen Claesen 1 collaboration

Yani Sim 1 collaboration

Idrish Ali 1 collaboration

Annemie Van Eetveldt 1 collaboration

Tom Kalathil Raju 1 collaboration

Stefanie Dedeurwaerdere 1 collaboration

Laura Hellinen 1 collaboration

Xu Yan 1 collaboration

Reinis Svarcbahs 1 collaboration

Kati-Sisko Vellonen 1 collaboration

Henri Huttunen 1 collaboration

Arto Urtti 1 collaboration

Erik A A Wallen 1 collaboration

Cedric Joossen 1 collaboration

Adrienn Baán 1 collaboration

Jurgen Joossens 1 collaboration

Nathalie Cools 1 collaboration

Ellen Lanckacker 1 collaboration

Lieve Moons 1 collaboration

Kim Lemmens 1 collaboration

Peter Delputte 1 collaboration

Guy Caljon 1 collaboration

Louis Maes 1 collaboration

Filip Kiekens 1 collaboration

Paul Cos 1 collaboration

Besa Emini Veseli 1 collaboration

Paola Perrotta 1 collaboration

Anahita Abdali 1 collaboration

Stefano Bellosta 1 collaboration

Giovanni Monaco 1 collaboration

Geert Bultynck 1 collaboration

Wim Martinet 1 collaboration

Guido R Y De Meyer 1 collaboration

Kaat Kehoe 1 collaboration

Robert Verkerk 1 collaboration

Bart 's Jongers 1 collaboration

Esther Peters 1 collaboration

Samir Kumar-Singh 1 collaboration

Peter Pickkers 1 collaboration

Philippe G Jorens 1 collaboration

An De Decker 1 collaboration

Anke Peeraer 1 collaboration

Line Verckist 1 collaboration

Koen Jansen 1 collaboration

Rafaela Gladysz 1 collaboration

Nathalia M de Vasconcelos 1 collaboration

Amanda Gonçalves 1 collaboration

Rosa Martín-Pérez 1 collaboration

Nina Van Opdenbosch 1 collaboration

Anvesh Jallapally 1 collaboration

Mohamed Lamkanfi 1 collaboration

Renate van der Wekken-de Bruijne 1 collaboration

Filip Lemière 1 collaboration

Henri T Pätsi 1 collaboration

Mikael Jumppanen 1 collaboration

Johanna Uhari-Väänänen 1 collaboration

Francesca De Lorenzo 1 collaboration

Hengjing Cui 1 collaboration

Samuli Auno 1 collaboration

Janne Saharinen 1 collaboration

Erin Seppälä 1 collaboration

Nina Sipari 1 collaboration

Juha Savinainen 1 collaboration

Maija Lahtela-Kakkonen 1 collaboration

Erik A A Wallén 1 collaboration

Louis Lauwerys 1 collaboration

Lucas Beroske 1 collaboration

Angelo Solania 1 collaboration

Christel Vangestel 1 collaboration

Alan Miranda 1 collaboration

Nele Van Giel 1 collaboration

Karuna Adhikari 1 collaboration

Leonie Wyffels 1 collaboration

Dennis Wolan 1 collaboration

Filipe Elvas 1 collaboration