Claudio Caccia

Affiliations

Medical Genetics and Neurogenetic Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

Publications (23)

A microglial cell model for acyl-CoA oxidase 1 deficiency.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Avec: Q Raas , F-E Saih , C Gondcaille , D Trompier , Y Hamon , V Leoni , C Caccia , B Nasser , M Jadot , F Ménétrier , G Lizard , M Cherkaoui-Malki , P Andreoletti , S Savary

Matrix-assisted laser desorption/ionization mass spectrometry imaging as a new tool for molecular histopathology in epilepsy surgery.

Epilepsia

Avec: Cinzia Cagnoli , Dalia De Santis , Claudio Caccia , Italia Bongarzone , Giulia Capitoli , Laura Rossini , Michele Rizzi , Francesco Deleo , Laura Tassi , Marco de Curtis , Rita Garbelli

CRISPR/Cas9-mediated knockout of Abcd1 and Abcd2 genes in BV-2 cells: novel microglial models for X-linked Adrenoleukodystrophy.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Avec: Q Raas , C Gondcaille , Y Hamon , V Leoni , C Caccia , F Ménétrier , G Lizard , D Trompier , S Savary

Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol.

The Journal of steroid biochemistry and molecular biology

Avec: Randa Sghaier , Thomas Nury , Valerio Leoni , Claudio Caccia , Jean-Paul Pais De Barros , Ameur Cherif , Anne Vejux , Thibault Moreau , Khalifa Limem , Mohammad Samadi , John J Mackrill , Ahmed Slaheddine Masmoudi , Gérard Lizard , Amira Zarrouk

Trend of 25-hydroxycholesterol and 27-hydroxycholesterol plasma levels in patients affected by active chronic hepatitis B virus infection and inactive carriers.

The Journal of steroid biochemistry and molecular biology

Avec: Lucio Boglione , Claudio Caccia , Andrea Civra , Jessica Cusato , Antonio D'Avolio , Fiorella Biasi , David Lembo , Giovanni Di Perri , Giuseppe Poli , Valerio Leoni

Insights into kinetics, release, and behavioral effects of brain-targeted hybrid nanoparticles for cholesterol delivery in Huntington's disease.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Giulia Birolini , Marta Valenza , Ilaria Ottonelli , Alice Passoni , Monica Favagrossa , Jason T Duskey , Mauro Bombaci , Maria Angela Vandelli , Laura Colombo , Renzo Bagnati , Claudio Caccia , Valerio Leoni , Franco Taroni , Flavio Forni , Barbara Ruozi , Mario Salmona , Giovanni Tosi , Elena Cattaneo

SREBP2 gene therapy targeting striatal astrocytes ameliorates Huntington's disease phenotypes.

Brain : a journal of neurology

Avec: Giulia Birolini , Gianluca Verlengia , Francesca Talpo , Claudia Maniezzi , Lorena Zentilin , Mauro Giacca , Paola Conforti , Chiara Cordiglieri , Claudio Caccia , Valerio Leoni , Franco Taroni , Gerardo Biella , Michele Simonato , Elena Cattaneo , Marta Valenza

The role of glutamatergic neurotransmission in the motor and non-motor symptoms in Parkinson's disease: Clinical cases and a review of the literature.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Avec: Javier Pagonabarraga , Michele Tinazzi , Carla Caccia , Wolfgang H Jost

Molecular Genetics of Niemann-Pick Type C Disease in Italy: An Update on 105 Patients and Description of 18

Journal of clinical medicine

Avec: Andrea Dardis , Stefania Zampieri , Cinzia Gellera , Rosalba Carrozzo , Silvia Cattarossi , Paolo Peruzzo , Rosalia Dariol , Annalisa Sechi , Federica Deodato , Claudio Caccia , Daniela Verrigni , Serena Gasperini , Agata Fiumara , Simona Fecarotta , Miryam Carecchio , Massimiliano Filosto , Lucia Santoro , Barbara Borroni , Andrea Bordugo , Francesco Brancati , Cinzia V Russo , Maja Di Rocco , Antonio Toscano , Maurizio Scarpa , Bruno Bembi

The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients.

Redox biology

Avec: Alessandro Marcello , Andrea Civra , Rafaela Milan Bonotto , Lais Nascimento Alves , Sreejith Rajasekharan , Chiara Giacobone , Claudio Caccia , Roberta Cavalli , Marco Adami , Paolo Brambilla , David Lembo , Giuseppe Poli , Valerio Leoni

Octadecaneuropeptide (ODN) Induces N2a Cells Differentiation through a PKA/PLC/PKC/MEK/ERK-Dependent Pathway: Incidence on Peroxisome, Mitochondria, and Lipid Profiles.

Molecules (Basel, Switzerland)

Avec: Amira Namsi , Thomas Nury , Amira S Khan , Jérôme Leprince , David Vaudry , Claudio Caccia , Valerio Leoni , Atanas G Atanasov , Marie-Christine Tonon , Olfa Masmoudi-Kouki , Gérard Lizard

Antiviral oxysterols are present in human milk at diverse stages of lactation.

The Journal of steroid biochemistry and molecular biology

Avec: Andrea Civra , Valerio Leoni , Claudio Caccia , Stefano Sottemano , Paola Tonetto , Alessandra Coscia , Chiara Peila , Guido E Moro , Pietro Gaglioti , Enrico Bertino , Giuseppe Poli , David Lembo

First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography-Urgent need for harmonisation of analytical methods.

The Journal of steroid biochemistry and molecular biology

Avec: Dieter Lütjohann , Ingemar Björkhem , Silvia Friedrichs , Anja Kerksiek , Anita Lövgren-Sandblom , Wolf-Jochen Geilenkeuser , Robert Ahrends , Isabel Andrade , Diana Ansorena , Iciar Astiasarán , Lucía Baila-Rueda , Bianca Barriuso , Susen Becker , Lionel Bretillon , Richard W Browne , Claudio Caccia , Uta Ceglarek , Ana Cenarro , Peter J Crick , Günter Fauler , Guadalupe Garcia-Llatas , Robert Gray , William J Griffiths , Helena Gylling , Scott Harding , Christin Helmschrodt , Luigi Iuliano , Hans-Gerd Janssen , Peter Jones , Leena Kaipiainen , Frank Kannenberg , María Jesús Lagarda , Valerio Leoni , Ana Maria Lottenberg , Dylan S MacKay , Silke Matysik , Jeff McDonald , Maria Menendez-Carreño , Semone B Myrie , Valéria Sutti Nunes , Richard E Ostlund , Eliana Polisecki , Fernando Ramos , Todd C Rideout , Ernst J Schaefer , Gerd Schmitz , Yuqin Wang , Chiara Zerbinati , Ulf Diczfalusy , Hans-Frieder Schött

Hsp22 overexpression induces myocardial hypertrophy, senescence and reduced life span through enhanced oxidative stress.

Free radical biology & medicine

Avec: Didier Morin , Romain Long , Mathieu Panel , Lydie Laure , Adela Taranu , Cindy Gueguen , Sandrine Pons , Valerio Leoni , Claudio Caccia , Stephen F Vatner , Dorothy E Vatner , Hongyu Qiu , Christophe Depre , Alain Berdeaux , Bijan Ghaleh

Safinamide inhibits in vivo glutamate release in a rat model of Parkinson's disease.

Neuropharmacology

Avec: Clarissa A Pisanò , Alberto Brugnoli , Salvatore Novello , Carla Caccia , Charlotte Keywood , Elsa Melloni , Silvia Vailati , Gloria Padoani , Michele Morari

Striatal infusion of cholesterol promotes dose-dependent behavioral benefits and exerts disease-modifying effects in Huntington's disease mice.

EMBO molecular medicine

Avec: Giulia Birolini , Marta Valenza , Eleonora Di Paolo , Elena Vezzoli , Francesca Talpo , Claudia Maniezzi , Claudio Caccia , Valerio Leoni , Franco Taroni , Vittoria D Bocchi , Paola Conforti , Elisa Sogne , Lara Petricca , Cristina Cariulo , Margherita Verani , Andrea Caricasole , Andrea Falqui , Gerardo Biella , Elena Cattaneo

Preclinical study of the antimyotonic efficacy of safinamide in the myotonic mouse model.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Avec: Ileana Canfora , Concetta Altamura , Jean-Francois Desaphy , Brigida Boccanegra , Silvia Vailati , Carla Caccia , Elsa Melloni , Gloria Padoani , Annamaria De Luca , Sabata Pierno

Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2.

Redox biology

Avec: Erica Staurenghi , Valentina Cerrato , Paola Gamba , Gabriella Testa , Serena Giannelli , Valerio Leoni , Claudio Caccia , Annalisa Buffo , Wendy Noble , Beatriz Gomez Perez-Nievas , Gabriella Leonarduzzi

Effects of safinamide on the glutamatergic striatal network in experimental Parkinson's disease.

Neuropharmacology

Avec: Miriam Sciaccaluga , Petra Mazzocchetti , Guendalina Bastioli , Veronica Ghiglieri , Antonella Cardinale , Paolo Mosci , Carla Caccia , Charlotte Keywood , Elsa Melloni , Gloria Padoani , Silvia Vailati , Barbara Picconi , Paolo Calabresi , Alessandro Tozzi

Purple corn extract induces long-lasting reprogramming and M2 phenotypic switch of adipose tissue macrophages in obese mice.

Journal of translational medicine

Avec: Federica Tomay , Alessandra Marinelli , Valerio Leoni , Claudio Caccia , Andrea Matros , Hans-Peter Mock , Chiara Tonelli , Katia Petroni

Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration.

Free radical biology & medicine

Avec: D Rossin , I H K Dias , M Solej , I Milic , A R Pitt , N Iaia , L Scoppapietra , A Devitt , M Nano , M Degiuli , M Volante , C Caccia , V Leoni , H R Griffiths , C M Spickett , G Poli , F Biasi

Involvement of 27-Hydroxycholesterol in Mitotane Action on Adrenocortical Carcinoma.

Cells

Avec: Antonina Germano , Daniela Rossin , Valerio Leoni , Noemi Iaia , Laura Saba , Vittoria Basile , Soraya Puglisi , Claudio Caccia , Giuseppe Poli , Fiorella Biasi , Massimo Terzolo

Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo.

Experimental neurology

Avec: Jean-François Desaphy , Alessandro Farinato , Concetta Altamura , Michela De Bellis , Paola Imbrici , Nancy Tarantino , Carla Caccia , Elsa Melloni , Gloria Padoani , Silvia Vailati , Charlotte Keywood , Maria Rosaria Carratù , Annamaria De Luca , Diana Conte , Sabata Pierno

Réseau de co-auteurs

Valerio Leoni 13 collaborations

Carla Caccia 5 collaborations

Giuseppe Poli 4 collaborations

Elsa Melloni 4 collaborations

Silvia Vailati 4 collaborations

Gloria Padoani 4 collaborations

V Leoni 3 collaborations

C Caccia 3 collaborations

Andrea Civra 3 collaborations

David Lembo 3 collaborations

Giulia Birolini 3 collaborations

Marta Valenza 3 collaborations

Franco Taroni 3 collaborations

Elena Cattaneo 3 collaborations

Charlotte Keywood 3 collaborations

Q Raas 2 collaborations

C Gondcaille 2 collaborations

D Trompier 2 collaborations

Y Hamon 2 collaborations

F Ménétrier 2 collaborations

G Lizard 2 collaborations

S Savary 2 collaborations

Thomas Nury 2 collaborations

Gérard Lizard 2 collaborations

Fiorella Biasi 2 collaborations

Francesca Talpo 2 collaborations

Claudia Maniezzi 2 collaborations

Paola Conforti 2 collaborations

Gerardo Biella 2 collaborations

Concetta Altamura 2 collaborations

Annamaria De Luca 2 collaborations

Sabata Pierno 2 collaborations

F-E Saih 1 collaboration

B Nasser 1 collaboration

M Jadot 1 collaboration

M Cherkaoui-Malki 1 collaboration

P Andreoletti 1 collaboration

Cinzia Cagnoli 1 collaboration

Dalia De Santis 1 collaboration

Italia Bongarzone 1 collaboration

Giulia Capitoli 1 collaboration

Laura Rossini 1 collaboration

Michele Rizzi 1 collaboration

Francesco Deleo 1 collaboration

Laura Tassi 1 collaboration

Marco de Curtis 1 collaboration

Rita Garbelli 1 collaboration

Randa Sghaier 1 collaboration

Jean-Paul Pais De Barros 1 collaboration

Ameur Cherif 1 collaboration

Anne Vejux 1 collaboration

Thibault Moreau 1 collaboration

Khalifa Limem 1 collaboration

Mohammad Samadi 1 collaboration

John J Mackrill 1 collaboration

Ahmed Slaheddine Masmoudi 1 collaboration

Amira Zarrouk 1 collaboration

Lucio Boglione 1 collaboration

Jessica Cusato 1 collaboration

Antonio D'Avolio 1 collaboration

Giovanni Di Perri 1 collaboration

Ilaria Ottonelli 1 collaboration

Alice Passoni 1 collaboration

Monica Favagrossa 1 collaboration

Jason T Duskey 1 collaboration

Mauro Bombaci 1 collaboration

Maria Angela Vandelli 1 collaboration

Laura Colombo 1 collaboration

Renzo Bagnati 1 collaboration

Flavio Forni 1 collaboration

Barbara Ruozi 1 collaboration

Mario Salmona 1 collaboration

Giovanni Tosi 1 collaboration

Gianluca Verlengia 1 collaboration

Lorena Zentilin 1 collaboration

Mauro Giacca 1 collaboration

Chiara Cordiglieri 1 collaboration

Michele Simonato 1 collaboration

Javier Pagonabarraga 1 collaboration

Michele Tinazzi 1 collaboration

Wolfgang H Jost 1 collaboration

Andrea Dardis 1 collaboration

Stefania Zampieri 1 collaboration

Cinzia Gellera 1 collaboration

Rosalba Carrozzo 1 collaboration

Silvia Cattarossi 1 collaboration

Paolo Peruzzo 1 collaboration

Rosalia Dariol 1 collaboration

Annalisa Sechi 1 collaboration

Federica Deodato 1 collaboration

Daniela Verrigni 1 collaboration

Serena Gasperini 1 collaboration

Agata Fiumara 1 collaboration

Simona Fecarotta 1 collaboration

Miryam Carecchio 1 collaboration

Massimiliano Filosto 1 collaboration

Lucia Santoro 1 collaboration

Barbara Borroni 1 collaboration

Andrea Bordugo 1 collaboration

Francesco Brancati 1 collaboration

Cinzia V Russo 1 collaboration

Maja Di Rocco 1 collaboration

Antonio Toscano 1 collaboration

Maurizio Scarpa 1 collaboration

Bruno Bembi 1 collaboration

Alessandro Marcello 1 collaboration

Rafaela Milan Bonotto 1 collaboration

Lais Nascimento Alves 1 collaboration

Sreejith Rajasekharan 1 collaboration

Chiara Giacobone 1 collaboration

Roberta Cavalli 1 collaboration

Marco Adami 1 collaboration

Paolo Brambilla 1 collaboration

Amira Namsi 1 collaboration

Amira S Khan 1 collaboration

Jérôme Leprince 1 collaboration

David Vaudry 1 collaboration

Atanas G Atanasov 1 collaboration

Marie-Christine Tonon 1 collaboration

Olfa Masmoudi-Kouki 1 collaboration

Stefano Sottemano 1 collaboration

Paola Tonetto 1 collaboration

Alessandra Coscia 1 collaboration

Chiara Peila 1 collaboration

Guido E Moro 1 collaboration

Pietro Gaglioti 1 collaboration

Enrico Bertino 1 collaboration

Dieter Lütjohann 1 collaboration

Ingemar Björkhem 1 collaboration

Silvia Friedrichs 1 collaboration

Anja Kerksiek 1 collaboration

Anita Lövgren-Sandblom 1 collaboration

Wolf-Jochen Geilenkeuser 1 collaboration

Robert Ahrends 1 collaboration

Isabel Andrade 1 collaboration

Diana Ansorena 1 collaboration

Iciar Astiasarán 1 collaboration

Lucía Baila-Rueda 1 collaboration

Bianca Barriuso 1 collaboration

Susen Becker 1 collaboration

Lionel Bretillon 1 collaboration

Richard W Browne 1 collaboration

Uta Ceglarek 1 collaboration

Ana Cenarro 1 collaboration

Peter J Crick 1 collaboration

Günter Fauler 1 collaboration

Guadalupe Garcia-Llatas 1 collaboration

Robert Gray 1 collaboration

William J Griffiths 1 collaboration

Helena Gylling 1 collaboration

Scott Harding 1 collaboration

Christin Helmschrodt 1 collaboration

Luigi Iuliano 1 collaboration

Hans-Gerd Janssen 1 collaboration

Peter Jones 1 collaboration

Leena Kaipiainen 1 collaboration

Frank Kannenberg 1 collaboration

María Jesús Lagarda 1 collaboration

Ana Maria Lottenberg 1 collaboration

Dylan S MacKay 1 collaboration

Silke Matysik 1 collaboration

Jeff McDonald 1 collaboration

Maria Menendez-Carreño 1 collaboration

Semone B Myrie 1 collaboration

Valéria Sutti Nunes 1 collaboration

Richard E Ostlund 1 collaboration

Eliana Polisecki 1 collaboration

Fernando Ramos 1 collaboration

Todd C Rideout 1 collaboration

Ernst J Schaefer 1 collaboration

Gerd Schmitz 1 collaboration

Yuqin Wang 1 collaboration

Chiara Zerbinati 1 collaboration

Ulf Diczfalusy 1 collaboration

Hans-Frieder Schött 1 collaboration

Didier Morin 1 collaboration

Romain Long 1 collaboration

Mathieu Panel 1 collaboration

Lydie Laure 1 collaboration

Adela Taranu 1 collaboration

Cindy Gueguen 1 collaboration

Sandrine Pons 1 collaboration

Stephen F Vatner 1 collaboration

Dorothy E Vatner 1 collaboration

Hongyu Qiu 1 collaboration

Christophe Depre 1 collaboration

Alain Berdeaux 1 collaboration

Bijan Ghaleh 1 collaboration

Clarissa A Pisanò 1 collaboration

Alberto Brugnoli 1 collaboration

Salvatore Novello 1 collaboration

Michele Morari 1 collaboration

Eleonora Di Paolo 1 collaboration

Elena Vezzoli 1 collaboration

Vittoria D Bocchi 1 collaboration

Elisa Sogne 1 collaboration

Lara Petricca 1 collaboration

Cristina Cariulo 1 collaboration

Margherita Verani 1 collaboration

Andrea Caricasole 1 collaboration

Andrea Falqui 1 collaboration

Ileana Canfora 1 collaboration

Jean-Francois Desaphy 1 collaboration

Brigida Boccanegra 1 collaboration

Erica Staurenghi 1 collaboration

Valentina Cerrato 1 collaboration

Paola Gamba 1 collaboration

Gabriella Testa 1 collaboration

Serena Giannelli 1 collaboration

Annalisa Buffo 1 collaboration

Wendy Noble 1 collaboration

Beatriz Gomez Perez-Nievas 1 collaboration

Gabriella Leonarduzzi 1 collaboration

Miriam Sciaccaluga 1 collaboration

Petra Mazzocchetti 1 collaboration

Guendalina Bastioli 1 collaboration

Veronica Ghiglieri 1 collaboration

Antonella Cardinale 1 collaboration

Paolo Mosci 1 collaboration

Barbara Picconi 1 collaboration

Paolo Calabresi 1 collaboration

Alessandro Tozzi 1 collaboration

Federica Tomay 1 collaboration

Alessandra Marinelli 1 collaboration

Andrea Matros 1 collaboration

Hans-Peter Mock 1 collaboration

Chiara Tonelli 1 collaboration

Katia Petroni 1 collaboration

D Rossin 1 collaboration

I H K Dias 1 collaboration

M Solej 1 collaboration

I Milic 1 collaboration

A R Pitt 1 collaboration

N Iaia 1 collaboration

L Scoppapietra 1 collaboration

A Devitt 1 collaboration

M Nano 1 collaboration

M Degiuli 1 collaboration

M Volante 1 collaboration

H R Griffiths 1 collaboration

C M Spickett 1 collaboration

G Poli 1 collaboration

F Biasi 1 collaboration

Antonina Germano 1 collaboration

Daniela Rossin 1 collaboration

Noemi Iaia 1 collaboration

Laura Saba 1 collaboration

Vittoria Basile 1 collaboration

Soraya Puglisi 1 collaboration

Massimo Terzolo 1 collaboration

Jean-François Desaphy 1 collaboration

Alessandro Farinato 1 collaboration

Michela De Bellis 1 collaboration

Paola Imbrici 1 collaboration

Nancy Tarantino 1 collaboration

Maria Rosaria Carratù 1 collaboration

Diana Conte 1 collaboration