Ingemar Björkhem

Affiliations

Department of Laboratory Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.

Publications (19)

mRNA as a Novel Treatment Strategy for Hereditary Spastic Paraplegia Type 5.

Molecular therapy. Methods & clinical development

Avec: Stefan Hauser , Marion Poenisch , Yvonne Schelling , Philip Höflinger , Stefanie Schuster , Axel Teegler , Rabea Betten , Jan-Åke Gustafsson , Jeannette Hübener-Schmid , Thomas Schlake , Frédéric Chevessier-Tünnesen , Nigel Horscroft , Ludger Schöls

Dose-response relationship between dietary choline and lipid accumulation in pyloric enterocytes of Atlantic salmon (

The British journal of nutrition

Avec: Anne K G Hansen , Trond M Kortner , Vegard Denstadli , Kjell Måsøval , Hans J Grav , Åshild Krogdahl

24(

The Journal of biological chemistry

Avec: Spyridon Theofilopoulos , Willy Antoni Abreu de Oliveira , Shanzheng Yang , Eylan Yutuc , Ahmed Saeed , Jonas Abdel-Khalik , Abbe Ullgren , Angel Cedazo-Minguez , Yuqin Wang , William J Griffiths , Ernest Arenas

First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography-Urgent need for harmonisation of analytical methods.

The Journal of steroid biochemistry and molecular biology

Avec: Dieter Lütjohann , Silvia Friedrichs , Anja Kerksiek , Anita Lövgren-Sandblom , Wolf-Jochen Geilenkeuser , Robert Ahrends , Isabel Andrade , Diana Ansorena , Iciar Astiasarán , Lucía Baila-Rueda , Bianca Barriuso , Susen Becker , Lionel Bretillon , Richard W Browne , Claudio Caccia , Uta Ceglarek , Ana Cenarro , Peter J Crick , Günter Fauler , Guadalupe Garcia-Llatas , Robert Gray , William J Griffiths , Helena Gylling , Scott Harding , Christin Helmschrodt , Luigi Iuliano , Hans-Gerd Janssen , Peter Jones , Leena Kaipiainen , Frank Kannenberg , María Jesús Lagarda , Valerio Leoni , Ana Maria Lottenberg , Dylan S MacKay , Silke Matysik , Jeff McDonald , Maria Menendez-Carreño , Semone B Myrie , Valéria Sutti Nunes , Richard E Ostlund , Eliana Polisecki , Fernando Ramos , Todd C Rideout , Ernst J Schaefer , Gerd Schmitz , Yuqin Wang , Chiara Zerbinati , Ulf Diczfalusy , Hans-Frieder Schött

Sex difference in flux of 27-hydroxycholesterol into the brain.

British journal of pharmacology

Avec: Cristina Parrado-Fernandez , Valerio Leoni , Ahmed Saeed , Patricia Rodriguez-Rodriguez , Anna Sandebring-Matton , Carmen M Córdoba-Beldad , Paula Bueno , Chaitanya Chakravarthi Gali , Ute Panzenboeck , Angel Cedazo-Minguez ,

Novel findings in a Swedish primary familial brain calcification cohort.

Journal of the neurological sciences

Avec: Stefan Sennfält , Peter Gustavsson , Helena Malmgren , Eric Gilland , Håkan Almqvist , Mikael Oscarson , Martin Engvall , Daniel Nilsson , Kristina Lagerstedt-Robinson , Per Svenningsson , Martin Paucar

Formation and metabolism of oxysterols and cholestenoic acids found in the mouse circulation: Lessons learnt from deuterium-enrichment experiments and the CYP46A1 transgenic mouse.

The Journal of steroid biochemistry and molecular biology

Avec: Peter J Crick , Eylan Yutuc , Jonas Abdel-Khalik , Ahmed Saeed , Christer Betsholtz , Guillem Genove , Yuqin Wang , William J Griffiths

Choline supplementation prevents diet induced gut mucosa lipid accumulation in post-smolt Atlantic salmon (Salmo salar L.).

BMC veterinary research

Avec: Anne Kristine G Hansen , Trond M Kortner , Aleksei Krasnov , Michael Penn , Åshild Krogdahl

Further evidence for a continuous flux of bile acids into the brain: trapping of bile acids in subdural hematomas.

Scandinavian journal of clinical and laboratory investigation

Avec: Emanuele Porru , Erik Edström , Ahmed A Saeed , Gösta Eggertsen , Anita Lövgren-Sandblom , Aldo Roda ,

Longitudinal Data in Patients with Niemann-Pick Type C Disease Under Combined High Intrathecal and Low Intravenous Dose of 2-hydroxylpropyl-β-cyclodextrin.

Innovations in clinical neuroscience

Avec: Evangelia Bountouvi , Melpomeni Giorgi , Anna Papadopoulou , Kaj Blennow , Maria Tsirouda , Spyridon Kanellakis , Andreas Fryganas , Maria Spanou , Ioanna Georgaki , Sofia Asprogeraka , Argyrios Dinopoulos

CYP46A1-mediated cholesterol turnover induces sex-specific changes in cognition and counteracts memory loss in ovariectomized mice.

Science advances

Avec: María Latorre-Leal , Patricia Rodriguez-Rodriguez , Luca Franchini , Orestis Nikolidakis , Makrina Daniilidou , Ljerka Delac , Mukesh K Varshney , Luis E Arroyo-García , Francesca Eroli , Bengt Winblad , Kaj Blennow , Henrik Zetterberg , Miia Kivipelto , Manuela Pacciarini , Yuqin Wang , William J Griffiths , Anna Matton , Ivan Nalvarte , Paula Merino-Serrais , Angel Cedazo-Minguez , Silvia Maioli

Ventriculoperitoneal Shunt Treatment Increases 7 Alpha Hy-Droxy-3-Oxo-4-Cholestenoic Acid and 24-Hydroxycholesterol Concentrations in Idiopathic Normal Pressure Hydrocephalus.

Brain sciences

Avec: Emanuele Porru , Erik Edström , Lisa Arvidsson , Adrian Elmi-Terander , Alexander Fletcher-Sandersjöö , Anita Lövgren Sandblom , Magnus Hansson , Frida Duell ,

27-Hydroxycholesterol Induces Aberrant Morphology and Synaptic Dysfunction in Hippocampal Neurons.

Cerebral cortex (New York, N.Y. : 1991)

Avec: Paula Merino-Serrais , Raul Loera-Valencia , Patricia Rodriguez-Rodriguez , Cristina Parrado-Fernandez , Muhammad A Ismail , Silvia Maioli , Eduardo Matute , Eva Maria Jimenez-Mateos , Javier DeFelipe , Angel Cedazo-Minguez

On the fluxes of side-chain oxidized oxysterols across blood-brain and blood-CSF barriers and origin of these steroids in CSF (Review).

The Journal of steroid biochemistry and molecular biology

Avec: Valerio Leoni , Per Svenningsson

27-Hydroxycholesterol, cognition, and brain imaging markers in the FINGER randomized controlled trial.

Alzheimer's research & therapy

Avec: Anna Sandebring-Matton , Julen Goikolea , Laura Paternain , Nina Kemppainen , Tiina Laatikainen , Tiia Ngandu , Juha Rinne , Hilkka Soininen , Angel Cedazo-Minguez , Alina Solomon , Miia Kivipelto

Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: Potential importance of pathway intermediates.

The Journal of steroid biochemistry and molecular biology

Avec: Jonas Abdel-Khalik , Thomas Hearn , Alison L Dickson , Peter J Crick , Eylan Yutuc , Karl Austin-Muttitt , Brian W Bigger , Andrew A Morris , Cedric H Shackleton , Peter T Clayton , Takashi Iida , Ria Sircar , Rajat Rohatgi , Hanns-Ulrich Marschall , Jan Sjövall , Jonathan G L Mullins , William J Griffiths , Yuqin Wang

Hypercholesterolemia and 27-Hydroxycholesterol Increase S100A8 and RAGE Expression in the Brain: a Link Between Cholesterol, Alarmins, and Neurodegeneration.

Molecular neurobiology

Avec: Raúl Loera-Valencia , Muhammad-Al-Mustafa Ismail , Julen Goikolea , Maria Lodeiro , Laura Mateos , Elena Puerta , Mariana A Romão , Cláudio M Gomes , Paula Merino-Serrais , Silvia Maioli , Angel Cedazo-Minguez

Different effects of CYP27A1 and CYP7B1 on cognitive function: Two mouse models in comparison.

The Journal of steroid biochemistry and molecular biology

Avec: Julen Goikolea , Maria Latorre-Leal , Christina Tsagkogianni , Sonja Pikkupeura , Balazs Gulyas , Angel Cedazo-Minguez , Raul Loera-Valencia , Patricia Rodriguez Rodriguez , Silvia Maioli

27-hydroxycholesterol promotes oligodendrocyte maturation: Implications for hypercholesterolemia-associated brain white matter changes.

Glia

Avec: Vilma Alanko , Adhara Gaminde-Blasco , Tania Quintela-López , Raúl Loera-Valencia , Alina Solomon , Angel Cedazo-Minguez , Silvia Maioli , Graziella Tabacaru , María Latorre-Leal , Carlos Matute , Miia Kivipelto , Elena Alberdi , Anna Sandebring-Matton

Réseau de co-auteurs

Angel Cedazo-Minguez 8 collaborations

Yuqin Wang 5 collaborations

William J Griffiths 5 collaborations

Silvia Maioli 5 collaborations

Eylan Yutuc 3 collaborations

Ahmed Saeed 3 collaborations

Jonas Abdel-Khalik 3 collaborations

Peter J Crick 3 collaborations

Valerio Leoni 3 collaborations

Patricia Rodriguez-Rodriguez 3 collaborations

Anna Sandebring-Matton 3 collaborations

Miia Kivipelto 3 collaborations

Paula Merino-Serrais 3 collaborations

Julen Goikolea 3 collaborations

Trond M Kortner 2 collaborations

Åshild Krogdahl 2 collaborations

Anita Lövgren-Sandblom 2 collaborations

Cristina Parrado-Fernandez 2 collaborations

Per Svenningsson 2 collaborations

Emanuele Porru 2 collaborations

Erik Edström 2 collaborations

Kaj Blennow 2 collaborations

María Latorre-Leal 2 collaborations

Raul Loera-Valencia 2 collaborations

Alina Solomon 2 collaborations

Raúl Loera-Valencia 2 collaborations

Stefan Hauser 1 collaboration

Marion Poenisch 1 collaboration

Yvonne Schelling 1 collaboration

Philip Höflinger 1 collaboration

Stefanie Schuster 1 collaboration

Axel Teegler 1 collaboration

Rabea Betten 1 collaboration

Jan-Åke Gustafsson 1 collaboration

Jeannette Hübener-Schmid 1 collaboration

Thomas Schlake 1 collaboration

Frédéric Chevessier-Tünnesen 1 collaboration

Nigel Horscroft 1 collaboration

Ludger Schöls 1 collaboration

Anne K G Hansen 1 collaboration

Vegard Denstadli 1 collaboration

Kjell Måsøval 1 collaboration

Hans J Grav 1 collaboration

Spyridon Theofilopoulos 1 collaboration

Willy Antoni Abreu de Oliveira 1 collaboration

Shanzheng Yang 1 collaboration

Abbe Ullgren 1 collaboration

Ernest Arenas 1 collaboration

Dieter Lütjohann 1 collaboration

Silvia Friedrichs 1 collaboration

Anja Kerksiek 1 collaboration

Wolf-Jochen Geilenkeuser 1 collaboration

Robert Ahrends 1 collaboration

Isabel Andrade 1 collaboration

Diana Ansorena 1 collaboration

Iciar Astiasarán 1 collaboration

Lucía Baila-Rueda 1 collaboration

Bianca Barriuso 1 collaboration

Susen Becker 1 collaboration

Lionel Bretillon 1 collaboration

Richard W Browne 1 collaboration

Claudio Caccia 1 collaboration

Uta Ceglarek 1 collaboration

Ana Cenarro 1 collaboration

Günter Fauler 1 collaboration

Guadalupe Garcia-Llatas 1 collaboration

Robert Gray 1 collaboration

Helena Gylling 1 collaboration

Scott Harding 1 collaboration

Christin Helmschrodt 1 collaboration

Luigi Iuliano 1 collaboration

Hans-Gerd Janssen 1 collaboration

Peter Jones 1 collaboration

Leena Kaipiainen 1 collaboration

Frank Kannenberg 1 collaboration

María Jesús Lagarda 1 collaboration

Ana Maria Lottenberg 1 collaboration

Dylan S MacKay 1 collaboration

Silke Matysik 1 collaboration

Jeff McDonald 1 collaboration

Maria Menendez-Carreño 1 collaboration

Semone B Myrie 1 collaboration

Valéria Sutti Nunes 1 collaboration

Richard E Ostlund 1 collaboration

Eliana Polisecki 1 collaboration

Fernando Ramos 1 collaboration

Todd C Rideout 1 collaboration

Ernst J Schaefer 1 collaboration

Gerd Schmitz 1 collaboration

Chiara Zerbinati 1 collaboration

Ulf Diczfalusy 1 collaboration

Hans-Frieder Schött 1 collaboration

Carmen M Córdoba-Beldad 1 collaboration

Paula Bueno 1 collaboration

Chaitanya Chakravarthi Gali 1 collaboration

Ute Panzenboeck 1 collaboration

Stefan Sennfält 1 collaboration

Peter Gustavsson 1 collaboration

Helena Malmgren 1 collaboration

Eric Gilland 1 collaboration

Håkan Almqvist 1 collaboration

Mikael Oscarson 1 collaboration

Martin Engvall 1 collaboration

Daniel Nilsson 1 collaboration

Kristina Lagerstedt-Robinson 1 collaboration

Martin Paucar 1 collaboration

Christer Betsholtz 1 collaboration

Guillem Genove 1 collaboration

Anne Kristine G Hansen 1 collaboration

Aleksei Krasnov 1 collaboration

Michael Penn 1 collaboration

Ahmed A Saeed 1 collaboration

Gösta Eggertsen 1 collaboration

Aldo Roda 1 collaboration

Evangelia Bountouvi 1 collaboration

Melpomeni Giorgi 1 collaboration

Anna Papadopoulou 1 collaboration

Maria Tsirouda 1 collaboration

Spyridon Kanellakis 1 collaboration

Andreas Fryganas 1 collaboration

Maria Spanou 1 collaboration

Ioanna Georgaki 1 collaboration

Sofia Asprogeraka 1 collaboration

Argyrios Dinopoulos 1 collaboration

Luca Franchini 1 collaboration

Orestis Nikolidakis 1 collaboration

Makrina Daniilidou 1 collaboration

Ljerka Delac 1 collaboration

Mukesh K Varshney 1 collaboration

Luis E Arroyo-García 1 collaboration

Francesca Eroli 1 collaboration

Bengt Winblad 1 collaboration

Henrik Zetterberg 1 collaboration

Manuela Pacciarini 1 collaboration

Anna Matton 1 collaboration

Ivan Nalvarte 1 collaboration

Lisa Arvidsson 1 collaboration

Adrian Elmi-Terander 1 collaboration

Alexander Fletcher-Sandersjöö 1 collaboration

Anita Lövgren Sandblom 1 collaboration

Magnus Hansson 1 collaboration

Frida Duell 1 collaboration

Muhammad A Ismail 1 collaboration

Eduardo Matute 1 collaboration

Eva Maria Jimenez-Mateos 1 collaboration

Javier DeFelipe 1 collaboration

Laura Paternain 1 collaboration

Nina Kemppainen 1 collaboration

Tiina Laatikainen 1 collaboration

Tiia Ngandu 1 collaboration

Juha Rinne 1 collaboration

Hilkka Soininen 1 collaboration

Thomas Hearn 1 collaboration

Alison L Dickson 1 collaboration

Karl Austin-Muttitt 1 collaboration

Brian W Bigger 1 collaboration

Andrew A Morris 1 collaboration

Cedric H Shackleton 1 collaboration

Peter T Clayton 1 collaboration

Takashi Iida 1 collaboration

Ria Sircar 1 collaboration

Rajat Rohatgi 1 collaboration

Hanns-Ulrich Marschall 1 collaboration

Jan Sjövall 1 collaboration

Jonathan G L Mullins 1 collaboration

Muhammad-Al-Mustafa Ismail 1 collaboration

Maria Lodeiro 1 collaboration

Laura Mateos 1 collaboration

Elena Puerta 1 collaboration

Mariana A Romão 1 collaboration

Cláudio M Gomes 1 collaboration

Maria Latorre-Leal 1 collaboration

Christina Tsagkogianni 1 collaboration

Sonja Pikkupeura 1 collaboration

Balazs Gulyas 1 collaboration

Patricia Rodriguez Rodriguez 1 collaboration

Vilma Alanko 1 collaboration

Adhara Gaminde-Blasco 1 collaboration

Tania Quintela-López 1 collaboration

Graziella Tabacaru 1 collaboration

Carlos Matute 1 collaboration

Elena Alberdi 1 collaboration