Christian M Beusch

Affiliations

Division of Physiological Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institute 17176 Stockholm, Sweden.

Publications (17)

Therapy targeting antigen-specific T cells by a peptide-based tolerizing vaccine against autoimmune arthritis.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Vilma Urbonaviciute , Laura Romero-Castillo , Bingze Xu , Huqiao Luo , Nadine Schneider , Sylvia Weisse , Nhu-Nguyen Do , Ana Oliveira-Coelho , Gonzalo Fernandez Lahore , Taotao Li , Pierre Sabatier , Christian M Beusch , Johan Viljanen , Roman A Zubarev , Jan Kihlberg , Johan Bäcklund , Harald Burkhardt , Rikard Holmdahl

Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin.

Redox biology

Avec: Amir Ata Saei , Hjalmar Gullberg , Pierre Sabatier , Christian M Beusch , Katarina Johansson , Bo Lundgren , Per I Arvidsson , Elias S J Arnér , Roman A Zubarev

An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation.

Nature communications

Avec: Pierre Sabatier , Christian M Beusch , Amir A Saei , Mike Aoun , Noah Moruzzi , Ana Coelho , Niels Leijten , Magnus Nordenskjöld , Patrick Micke , Diana Maltseva , Alexander G Tonevitsky , Vincent Millischer , J Carlos Villaescusa , Sandeep Kadekar , Massimiliano Gaetani , Kamilya Altynbekova , Alexander Kel , Per-Olof Berggren , Oscar Simonson , Karl-Henrik Grinnemo , Rikard Holmdahl , Sergey Rodin , Roman A Zubarev

Analysis of local extracellular matrix identifies different aetiologies behind bicuspid and tricuspid aortic valve degeneration and suggests therapies.

Cellular and molecular life sciences : CMLS

Avec: Christian M Beusch , Oscar E Simonson , Johan O Wedin , Pierre Sabatier , Ulrika Felldin , Sandeep Kadekar , Cecilia Österholm , Ákos Végvári , Roman A Zubarev , Karin Fromell , Bo Nilson , Stefan James , Elisabeth Ståhle , Karl-Henrik Grinnemo , Sergey Rodin

ProTargetMiner as a proteome signature library of anticancer molecules for functional discovery.

Nature communications

Avec: Amir Ata Saei , Christian Michel Beusch , Alexey Chernobrovkin , Pierre Sabatier , Bo Zhang , Ülkü Güler Tokat , Eleni Stergiou , Massimiliano Gaetani , Ákos Végvári , Roman A Zubarev

A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis.

Nature communications

Avec: Yibo He , Changrong Ge , Àlex Moreno-Giró , Bingze Xu , Christian M Beusch , Katalin Sandor , Jie Su , Lei Cheng , Erik Lönnblom , Christina Lundqvist , Linda M Slot , Dongmei Tong , Vilma Urbonaviciute , Bibo Liang , Taotao Li , Gonzalo Fernandez Lahore , Mike Aoun , Vivianne Malmström , Theo Rispens , Patrik Ernfors , Camilla I Svensson , Hans Ulrich Scherer , René E M Toes , Inger Gjertsson , Olov Ekwall , Roman A Zubarev , Rikard Holmdahl

System-Wide Profiling by Proteome Integral Solubility Alteration Assay of Drug Residence Times for Target Characterization.

Analytical chemistry

Avec: Pierre Sabatier , Christian M Beusch , Zhaowei Meng , Roman A Zubarev

Proteome Integral Solubility Alteration: A High-Throughput Proteomics Assay for Target Deconvolution.

Journal of proteome research

Avec: Massimiliano Gaetani , Pierre Sabatier , Amir A Saei , Christian M Beusch , Zhe Yang , Susanna L Lundström , Roman A Zubarev

GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics.

Nature communications

Avec: Shane C Wright , Aikaterini Motso , Stefania Koutsilieri , Christian M Beusch , Pierre Sabatier , Alessandro Berghella , Élodie Blondel-Tepaz , Kimberley Mangenot , Ioannis Pittarokoilis , Despoina-Christina Sismanoglou , Christian Le Gouill , Jesper V Olsen , Roman A Zubarev , Nevin A Lambert , Alexander S Hauser , Michel Bouvier , Volker M Lauschke

Antigen-presenting autoreactive B cells activate regulatory T cells and suppress autoimmune arthritis in mice.

The Journal of experimental medicine

Avec: Mike Aoun , Ana Coelho , Alexander Krämer , Amit Saxena , Pierre Sabatier , Christian Michel Beusch , Erik Lönnblom , Manman Geng , Nhu-Nguyen Do , Zhongwei Xu , Jingdian Zhang , Yibo He , Laura Romero Castillo , Hassan Abolhassani , Bingze Xu , Johan Viljanen , Joanna Rorbach , Gonzalo Fernandez Lahore , Inger Gjertsson , Alf Kastbom , Christopher Sjöwall , Jan Kihlberg , Roman A Zubarev , Harald Burkhardt , Rikard Holmdahl

Ultralight Ultrafast Enzymes.

Angewandte Chemie (International ed. in English)

Avec: Xuepei Zhang , Zhaowei Meng , Christian M Beusch , Hassan Gharibi , Qing Cheng , Hezheng Lyu , Luciano Di Stefano , Jijing Wang , Amir A Saei , Ákos Végvári , Massimiliano Gaetani , Roman A Zubarev

Copper(I)-nitrene platform for chemoproteomic profiling of methionine.

Nature communications

Avec: Samrat Sahu , Benjamin Emenike , Christian Michel Beusch , Pritha Bagchi , David Ezra Gordon , Monika Raj

Comprehensive chemical proteomics analyses reveal that the new TRi-1 and TRi-2 compounds are more specific thioredoxin reductase 1 inhibitors than auranofin.

Redox biology

Avec: Pierre Sabatier , Christian M Beusch , Radosveta Gencheva , Qing Cheng , Roman Zubarev , Elias S J Arnér

System-wide identification and prioritization of enzyme substrates by thermal analysis.

Nature communications

Avec: Amir Ata Saei , Christian M Beusch , Pierre Sabatier , Juan Astorga Wells , Hassan Gharibi , Zhaowei Meng , Alexey Chernobrovkin , Sergey Rodin , Katja Näreoja , Ann-Gerd Thorsell , Tobias Karlberg , Qing Cheng , Susanna L Lundström , Massimiliano Gaetani , Ákos Végvári , Elias S J Arnér , Herwig Schüler , Roman A Zubarev

Ion-Based Proteome-Integrated Solubility Alteration Assays for Systemwide Profiling of Protein-Molecule Interactions.

Analytical chemistry

Avec: Christian M Beusch , Pierre Sabatier , Roman A Zubarev

Wnt/β-catenin and NFκB signaling synergize to trigger growth-factor-free regeneration of adult primary human hepatocytes.

Hepatology (Baltimore, Md.)

Avec: Nuria Oliva-Vilarnau , Christian M Beusch , Pierre Sabatier , Eirini Sakaraki , Amelie Tjaden , Lukas Graetz , Florian A Büttner , Debra Dorotea , My Nguyen , Filip Bergqvist , Yvonne Sundström , Susanne Müller , Roman A Zubarev , Gunnar Schulte , Claudia Tredup , Roberto Gramignoli , Uwe J F Tietge , Volker M Lauschke

Distinct SIV-specific CD8

Nature immunology

Avec: Zachary Strongin , Laurence Raymond Marchand , Claire Deleage , M Betina Pampena , Maria Andrea Cardenas , Christian Michel Beusch , Timothy N Hoang , Elizabeth A Urban , Mael Gourves , Kevin Nguyen , Gregory K Tharp , Stacey Lapp , Andrew R Rahmberg , Justin Harper , Perla M Del Rio Estrada , Mauricio Gonzalez-Navarro , Fernanda Torres-Ruiz , Yara Andrea Luna-Villalobos , Santiago Avila-Rios , Gustavo Reyes-Teran , Rafick Sekaly , Guido Silvestri , Deanna A Kulpa , Asier Saez-Cirion , Jason M Brenchley , Steven E Bosinger , David Ezra Gordon , Michael R Betts , Haydn T Kissick , Mirko Paiardini

Réseau de co-auteurs

Roman A Zubarev 14 collaborations

Pierre Sabatier 13 collaborations

Massimiliano Gaetani 5 collaborations

Rikard Holmdahl 4 collaborations

Ákos Végvári 4 collaborations

Christian Michel Beusch 4 collaborations

Bingze Xu 3 collaborations

Gonzalo Fernandez Lahore 3 collaborations

Amir Ata Saei 3 collaborations

Elias S J Arnér 3 collaborations

Amir A Saei 3 collaborations

Mike Aoun 3 collaborations

Sergey Rodin 3 collaborations

Zhaowei Meng 3 collaborations

Qing Cheng 3 collaborations

Vilma Urbonaviciute 2 collaborations

Nhu-Nguyen Do 2 collaborations

Taotao Li 2 collaborations

Johan Viljanen 2 collaborations

Jan Kihlberg 2 collaborations

Harald Burkhardt 2 collaborations

Ana Coelho 2 collaborations

Sandeep Kadekar 2 collaborations

Karl-Henrik Grinnemo 2 collaborations

Alexey Chernobrovkin 2 collaborations

Yibo He 2 collaborations

Erik Lönnblom 2 collaborations

Inger Gjertsson 2 collaborations

Susanna L Lundström 2 collaborations

Volker M Lauschke 2 collaborations

Hassan Gharibi 2 collaborations

David Ezra Gordon 2 collaborations

Laura Romero-Castillo 1 collaboration

Huqiao Luo 1 collaboration

Nadine Schneider 1 collaboration

Sylvia Weisse 1 collaboration

Ana Oliveira-Coelho 1 collaboration

Johan Bäcklund 1 collaboration

Hjalmar Gullberg 1 collaboration

Katarina Johansson 1 collaboration

Bo Lundgren 1 collaboration

Per I Arvidsson 1 collaboration

Noah Moruzzi 1 collaboration

Niels Leijten 1 collaboration

Magnus Nordenskjöld 1 collaboration

Patrick Micke 1 collaboration

Diana Maltseva 1 collaboration

Alexander G Tonevitsky 1 collaboration

Vincent Millischer 1 collaboration

J Carlos Villaescusa 1 collaboration

Kamilya Altynbekova 1 collaboration

Alexander Kel 1 collaboration

Per-Olof Berggren 1 collaboration

Oscar Simonson 1 collaboration

Oscar E Simonson 1 collaboration

Johan O Wedin 1 collaboration

Ulrika Felldin 1 collaboration

Cecilia Österholm 1 collaboration

Karin Fromell 1 collaboration

Bo Nilson 1 collaboration

Stefan James 1 collaboration

Elisabeth Ståhle 1 collaboration

Bo Zhang 1 collaboration

Ülkü Güler Tokat 1 collaboration

Eleni Stergiou 1 collaboration

Changrong Ge 1 collaboration

Àlex Moreno-Giró 1 collaboration

Katalin Sandor 1 collaboration

Jie Su 1 collaboration

Lei Cheng 1 collaboration

Christina Lundqvist 1 collaboration

Linda M Slot 1 collaboration

Dongmei Tong 1 collaboration

Bibo Liang 1 collaboration

Vivianne Malmström 1 collaboration

Theo Rispens 1 collaboration

Patrik Ernfors 1 collaboration

Camilla I Svensson 1 collaboration

Hans Ulrich Scherer 1 collaboration

René E M Toes 1 collaboration

Olov Ekwall 1 collaboration

Zhe Yang 1 collaboration

Shane C Wright 1 collaboration

Aikaterini Motso 1 collaboration

Stefania Koutsilieri 1 collaboration

Alessandro Berghella 1 collaboration

Élodie Blondel-Tepaz 1 collaboration

Kimberley Mangenot 1 collaboration

Ioannis Pittarokoilis 1 collaboration

Despoina-Christina Sismanoglou 1 collaboration

Christian Le Gouill 1 collaboration

Jesper V Olsen 1 collaboration

Nevin A Lambert 1 collaboration

Alexander S Hauser 1 collaboration

Michel Bouvier 1 collaboration

Alexander Krämer 1 collaboration

Amit Saxena 1 collaboration

Manman Geng 1 collaboration

Zhongwei Xu 1 collaboration

Jingdian Zhang 1 collaboration

Laura Romero Castillo 1 collaboration

Hassan Abolhassani 1 collaboration

Joanna Rorbach 1 collaboration

Alf Kastbom 1 collaboration

Christopher Sjöwall 1 collaboration

Xuepei Zhang 1 collaboration

Hezheng Lyu 1 collaboration

Luciano Di Stefano 1 collaboration

Jijing Wang 1 collaboration

Samrat Sahu 1 collaboration

Benjamin Emenike 1 collaboration

Pritha Bagchi 1 collaboration

Monika Raj 1 collaboration

Radosveta Gencheva 1 collaboration

Roman Zubarev 1 collaboration

Juan Astorga Wells 1 collaboration

Katja Näreoja 1 collaboration

Ann-Gerd Thorsell 1 collaboration

Tobias Karlberg 1 collaboration

Herwig Schüler 1 collaboration

Nuria Oliva-Vilarnau 1 collaboration

Eirini Sakaraki 1 collaboration

Amelie Tjaden 1 collaboration

Lukas Graetz 1 collaboration

Florian A Büttner 1 collaboration

Debra Dorotea 1 collaboration

My Nguyen 1 collaboration

Filip Bergqvist 1 collaboration

Yvonne Sundström 1 collaboration

Susanne Müller 1 collaboration

Gunnar Schulte 1 collaboration

Claudia Tredup 1 collaboration

Roberto Gramignoli 1 collaboration

Uwe J F Tietge 1 collaboration

Zachary Strongin 1 collaboration

Laurence Raymond Marchand 1 collaboration

Claire Deleage 1 collaboration

M Betina Pampena 1 collaboration

Maria Andrea Cardenas 1 collaboration

Timothy N Hoang 1 collaboration

Elizabeth A Urban 1 collaboration

Mael Gourves 1 collaboration

Kevin Nguyen 1 collaboration

Gregory K Tharp 1 collaboration

Stacey Lapp 1 collaboration

Andrew R Rahmberg 1 collaboration

Justin Harper 1 collaboration

Perla M Del Rio Estrada 1 collaboration

Mauricio Gonzalez-Navarro 1 collaboration

Fernanda Torres-Ruiz 1 collaboration

Yara Andrea Luna-Villalobos 1 collaboration

Santiago Avila-Rios 1 collaboration

Gustavo Reyes-Teran 1 collaboration

Rafick Sekaly 1 collaboration

Guido Silvestri 1 collaboration

Deanna A Kulpa 1 collaboration

Asier Saez-Cirion 1 collaboration

Jason M Brenchley 1 collaboration

Steven E Bosinger 1 collaboration

Michael R Betts 1 collaboration

Haydn T Kissick 1 collaboration

Mirko Paiardini 1 collaboration